tryptophan has been researched along with Chronic Kidney Diseases in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (2.56) | 29.6817 |
| 2010's | 16 (41.03) | 24.3611 |
| 2020's | 22 (56.41) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, L; Fu, P; Guo, F; Ma, L; Ren, Q; Tao, S; Zhang, C | 1 |
| Arinze, N; Belghasem, M; Chitalia, VC; Dember, LM; Lee, N; Lotfollahzadeh, S; Napoleon, MA; Ravid, K; Richards, S; Russell, TL; Walker, JA; Whelan, SA; Yoo, SB | 1 |
| Guo, X; He, S; Li, L; Liang, W; Lin, X; Wang, H; Xiang, S; Xiong, Q; Yao, Y; Ying, C; Zhang, P; Zhao, J; Zuo, X | 1 |
| Anderson, S; Arinze, NV; Belghasem, M; Chitalia, VC; Farber, A; Francis, J; Hamburg, NM; Hassan Kamel, M; Lee, N; Lotfollahzadeh, S; Napoleon, MA; Rahimi, N; Ravid, JD; Richards, S; Sherr, D; Siracuse, JJ; Walker, JA; Whelan, SA; Yin, W | 1 |
| Burtey, S; Cerini, C; McKay, N; Poitevin, S; Vial, R | 1 |
| Burtey, S; Glorieux, G; Nigam, SK; Vanholder, R | 1 |
| Garssen, J; Madella, AM; Masereeuw, R; Overbeek, SA; Van Bergenhenegouwen, J | 1 |
| Falk, RJ; Li, Y; Schroder, M; Sumner, S; Zeitler, EM | 1 |
| Belghasem, M; Chitalia, VC; Jose, A; Lee, N; Lotfollahzadeh, S; Metrikova, E; Meyer, RD; Napoleon, MA; Rahimi, N; Sellinger, IE; Vazirani, A; Whelan, SA; Yang, X; Yin, W; Zhebrun, A | 1 |
| Guo, S; Han, M; Hui, Y; Ning, X; Qin, Y; Sun, S; Wang, A; Wang, Y; Xing, Y; Yu, Z; Yuan, J; Zhang, Y; Zhao, J; Zhao, Y | 1 |
| Ermakov, VS; Granados, JC; Nigam, SK | 1 |
| Adoberg, A; Arduan Ortiz, A; Arund, J; Dhondt, A; Fernström, A; Fridolin, I; Glorieux, G; Gonzalez-Parra, E; Leis, L; Luman, M; Paats, J; Perez-Gomez, VM; Pilt, K; Sanchez-Ospina, D; Segelmark, M; Uhlin, F | 1 |
| Brazier, F; Cheddani, L; Choukroun, G; Glorieux, G; Laville, SM; Liabeuf, S; Massy, ZA; Titeca Beauport, D; Valholder, R | 1 |
| Benvenga, S; Bolignano, D; Buemi, M; Cernaro, V; Cigala, RM; Crea, F; De Stefano, C; Ferlazzo, VT; Gembillo, G; Genovese, ARR; Loddo, S; Macaione, V; Santoro, D; Vita, R | 1 |
| Hsu, CN; Huang, LT; Lin, IC; Tain, YL; Tiao, MM; Yu, HR | 1 |
| Benkowitz, P; Cheng, Y; Köttgen, A; Lamina, C; Li, Y; Sekula, P | 1 |
| Cylwik, B; Domaniewski, T; Kalaska, B; Mor, A; Pawlak, D; Pawlak, K; Sieklucka, B; Zieminska, M | 1 |
| Deng, DQ; Li, P; Liu, JR; Miao, H; Vaziri, ND; Zhao, YY | 1 |
| Chen, C; Duan, J; Guo, J; Jiang, S; Li, J; Lu, J; Peng, Y; Wang, Y; Xu, X; Yu, J; Zhang, S | 1 |
| Hsu, CN; Tain, YL | 1 |
| Hermanowicz, JM; Kwiatkowska, I; Mysliwiec, M; Pawlak, D | 1 |
| Gu, Y; Ji, C; Jie, X; Liu, X; Lu, Z; Mo, Y; Wang, L | 1 |
| Borges, NA; Brito, JS; Esgalhado, M; Mafra, D; Magliano, DC; Soulage, CO | 1 |
| Esteras, R; Fernandez-Prado, R; Gonzalez-Parra, E; Gracia-Iguacel, C; Ortiz, A; Perez-Gomez, MV; Sanchez-Niño, MD; Sanz, AB | 1 |
| Dettmer, K; Eckardt, KU; Ellmann, L; Gronwald, W; Kastenmüller, G; Köttgen, A; Mohney, RP; Oefner, PJ; Sekula, P; Suhre, K; Vogl, FC | 1 |
| Appel, LJ; Arking, DE; Bottinger, E; Coresh, J; Evans, AM; Grams, ME; Inker, LA; Levey, AS; Lipkowitz, MS; Nadkarni, G; Rebholz, CM; Sarnak, MJ; Tin, A; Winkler, CA | 1 |
| Addi, T; Burtey, S; Dou, L | 1 |
| Argyopoulos, CP; Bayliss, GP; Cao, G; Chen, DQ; Chen, H; Chen, L; Cheng, XH; Guo, Y; Kang, H; Li, XR; Liu, D; Ma, SX; Mao, JR; Meng, MX; Samuels, DC; Shang, YQ; Su, W; Vaziri, ND; Wang, M; Ye, F; Yu, H; Yu, XY; Zhang, L; Zhang, Y; Zhao, J; Zhao, S; Zhao, YY; Zhuang, S | 1 |
| Chabielska, E; Kamiński, T; Kramkowski, K; Leszczyńska, A; Marcińczyk, N; Misztal, T; Pawlak, D | 1 |
| Zhao, J | 2 |
| Bao, YS; Ji, Y; Ma, LL; Na, SP; Xie, RJ; Zhao, SL | 1 |
| Brunet, P; Burtey, S; Cerini, C; Dou, L; Poitevin, S; Sallée, M | 1 |
| Carru, C; Mangoni, AA; Sanna, M; Satta, AE; Sotgia, S; Zinellu, A | 1 |
| Kalim, S; Rhee, EP | 1 |
| Davies, N; Hilder, EF; Jose, MD; Karu, N; McKercher, C; Nichols, DS; Shellie, RA | 1 |
| Devlin, AS; Dodd, D; Fischbach, MA; Marcobal, A; Meyer, T; Nayfach, S; Plummer, N; Pollard, KS; Sonnenburg, JL | 1 |
| Fotopoulou, C; Hasper, D; Pschowski, R; Reinke, P; Schefold, JC; Schuett, C; Volk, HD; von Haehling, S; Zeden, JP | 1 |
| Krzyściak, W | 1 |
12 review(s) available for tryptophan and Chronic Kidney Diseases
| Article | Year |
|---|---|
What If Not All Metabolites from the Uremic Toxin Generating Pathways Are Toxic? A Hypothesis.
Topics: Female; Humans; Indican; Liver; Male; Renal Insufficiency, Chronic; Toxins, Biological; Tryptophan; Uremia; Uremic Toxins | 2022 |
Microbial-Derived Tryptophan Catabolites, Kidney Disease and Gut Inflammation.
Topics: Fatty Acids, Volatile; Humans; Indican; Inflammation; Prebiotics; Pregnane X Receptor; Receptors, Aryl Hydrocarbon; Renal Insufficiency, Chronic; Tryptophan | 2022 |
The Role of Tryptophan Metabolism in the Occurrence and Progression of Acute and Chronic Kidney Diseases.
Topics: Acute Kidney Injury; Humans; Kynurenine; Renal Insufficiency, Chronic; Signal Transduction; Tryptophan | 2023 |
Gut microbiota-derived tryptophan metabolism mediates renal fibrosis by aryl hydrocarbon receptor signaling activation.
Topics: Biological Products; Cytochrome P-450 CYP2E1; Gastrointestinal Microbiome; Humans; Indoleacetic Acids; Polycyclic Aromatic Hydrocarbons; Receptors, Aryl Hydrocarbon; Renal Insufficiency, Chronic; Signal Transduction; Tryptophan | 2021 |
Developmental Programming and Reprogramming of Hypertension and Kidney Disease: Impact of Tryptophan Metabolism.
Topics: Animals; Female; Fetal Development; Gastrointestinal Microbiome; Humans; Hypertension; Metabolic Networks and Pathways; Pregnancy; Renal Insufficiency, Chronic; Tryptophan | 2020 |
Oxidative Storm Induced by Tryptophan Metabolites: Missing Link between Atherosclerosis and Chronic Kidney Disease.
Topics: Atherosclerosis; Humans; Metabolome; Models, Biological; Oxidative Stress; Renal Insufficiency, Chronic; Tryptophan | 2020 |
Aryl Hydrocarbon Receptor Activation in Chronic Kidney Disease: Role of Uremic Toxins.
Topics: Animals; Cardiovascular Diseases; Glucuronates; Humans; Indican; Indoleacetic Acids; Indoles; Models, Biological; Receptors, Aryl Hydrocarbon; Renal Insufficiency, Chronic; Toxins, Biological; Tryptophan; Uremia | 2017 |
Nutrients Turned into Toxins: Microbiota Modulation of Nutrient Properties in Chronic Kidney Disease.
Topics: Cardiovascular Diseases; Carnitine; Choline; Diet; Gastrointestinal Microbiome; Humans; Methylamines; Micronutrients; Oxalates; Phosphates; Phosphatidylcholines; Renal Insufficiency, Chronic; Tryptophan; Tyrosine | 2017 |
Tryptophan-Derived Uremic Toxins and Thrombosis in Chronic Kidney Disease.
Topics: Animals; Diet; Humans; Microbiota; Renal Insufficiency, Chronic; Thrombosis; Toxins, Biological; Tryptophan; Uremia | 2018 |
The aryl hydrocarbon receptor-activating effect of uremic toxins from tryptophan metabolism: a new concept to understand cardiovascular complications of chronic kidney disease.
Topics: Animals; Cardiovascular Diseases; Endothelium, Vascular; Humans; Leukocytes; Oxidative Stress; Receptors, Aryl Hydrocarbon; Renal Insufficiency, Chronic; Toxins, Biological; Tryptophan; Uremia | 2014 |
An overview of renal metabolomics.
Topics: Acute Kidney Injury; Analytic Sample Preparation Methods; Cardiovascular Diseases; Diabetic Nephropathies; Humans; Kidney; Magnetic Resonance Spectroscopy; Mass Spectrometry; Metabolome; Metabolomics; Methylamines; Mitochondria; Renal Insufficiency, Chronic; Tryptophan | 2017 |
Activity of selected aromatic amino acids in biological systems.
Topics: Biomarkers; Cardiovascular Diseases; Enzyme Activation; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Levodopa; Melanins; Monophenol Monooxygenase; Nervous System Diseases; Oxidative Stress; Renal Insufficiency, Chronic; Serotonin; Tryptophan; Tyrosine | 2011 |
2 trial(s) available for tryptophan and Chronic Kidney Diseases
| Article | Year |
|---|---|
Plasma kynurenic acid/tryptophan ratio: a sensitive and reliable biomarker for the assessment of renal function.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Female; Humans; Hypertension; Kidney Function Tests; Kynurenic Acid; Kynurenine; Male; Middle Aged; Renal Insufficiency, Chronic; Tryptophan | 2013 |
Impact of cholesterol lowering treatment on plasma kynurenine and tryptophan concentrations in chronic kidney disease: relationship with oxidative stress improvement.
Topics: Aged; Allantoin; Anticholesteremic Agents; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Dose-Response Relationship, Drug; Ezetimibe; Female; Healthy Volunteers; Humans; Inflammation; Kynurenine; Male; Malondialdehyde; Middle Aged; NF-kappa B; Oxidative Stress; Renal Insufficiency, Chronic; Simvastatin; Taurine; Triglycerides; Tryptophan; Uric Acid | 2015 |
25 other study(ies) available for tryptophan and Chronic Kidney Diseases
| Article | Year |
|---|---|
Fisetin Improves Hyperuricemia-Induced Chronic Kidney Disease via Regulating Gut Microbiota-Mediated Tryptophan Metabolism and Aryl Hydrocarbon Receptor Activation.
Topics: Animals; Flavonols; Gastrointestinal Microbiome; Hyperuricemia; Mice; Receptors, Aryl Hydrocarbon; Renal Insufficiency, Chronic; Tryptophan | 2021 |
Indoleamine 2,3-dioxygenase-1, a Novel Therapeutic Target for Post-Vascular Injury Thrombosis in CKD.
Topics: Animals; Aorta; Carotid Artery Injuries; Carotid Artery Thrombosis; Culture Media; Enzyme Induction; Feedback, Physiological; Female; HEK293 Cells; Humans; Indican; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Targeted Therapy; Myocytes, Smooth Muscle; Postoperative Complications; Renal Insufficiency, Chronic; Thromboplastin; Thrombosis; Tryptophan; Uremia; Vascular Surgical Procedures | 2021 |
The Accumulation of Gut Microbiome-derived Indoxyl Sulfate and P-Cresyl Sulfate in Patients With End-stage Renal Disease.
Topics: Cresols; Dialysis Solutions; Gastrointestinal Microbiome; Humans; Indican; Indoles; Kidney Failure, Chronic; Renal Insufficiency, Chronic; RNA, Ribosomal, 16S; Sulfates; Sulfuric Acid Esters; Tryptophan | 2022 |
Tryptophan metabolites suppress the Wnt pathway and promote adverse limb events in chronic kidney disease.
Topics: Aged; Aged, 80 and over; Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Line; Disease Models, Animal; Hindlimb; Humans; Indican; Ischemia; Kynurenine; Mice; Middle Aged; Receptors, Aryl Hydrocarbon; Renal Insufficiency, Chronic; Tryptophan; Wnt Signaling Pathway | 2022 |
Tryptophan Metabolites Regulate Neuropentraxin 1 Expression in Endothelial Cells.
Topics: Animals; C-Reactive Protein; Carbazoles; Cells, Cultured; Disease Models, Animal; Human Umbilical Vein Endothelial Cells; Humans; Indican; Indoleacetic Acids; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Renal Insufficiency, Chronic; Toxins, Biological; Tryptophan; Uremia | 2022 |
Characterizing the metabolic response of the zebrafish kidney to overfeeding.
Topics: Animals; Kidney; Obesity; Renal Insufficiency, Chronic; Tryptophan; Zebrafish | 2023 |
Tryptophan Metabolites Target Transmembrane and Immunoglobulin Domain-Containing 1 Signaling to Augment Renal Tubular Injury.
Topics: Animals; Humans; Immunoglobulin Domains; Kidney; Membrane Glycoproteins; Mice; Renal Insufficiency, Chronic; Tryptophan; Uremic Toxins | 2023 |
Remote effects of kidney drug transporter OAT1 on gut microbiome composition and urate homeostasis.
Topics: Animals; Gastrointestinal Microbiome; Homeostasis; Kidney; Membrane Transport Proteins; Mice; Renal Insufficiency, Chronic; Tryptophan; Uric Acid | 2023 |
Serum Levels and Removal by Haemodialysis and Haemodiafiltration of Tryptophan-Derived Uremic Toxins in ESKD Patients.
Topics: Adult; Aged; Aged, 80 and over; Female; Hemodiafiltration; Humans; Indican; Indoleacetic Acids; Kidney Failure, Chronic; Male; Middle Aged; Prospective Studies; Renal Dialysis; Renal Insufficiency, Chronic; Tryptophan | 2020 |
Difference in Profiles of the Gut-Derived Tryptophan Metabolite Indole Acetic Acid between Transplanted and Non-Transplanted Patients with Chronic Kidney Disease.
Topics: Adult; Aged; Biomarkers; Female; Glomerular Filtration Rate; Graft Survival; Humans; Indoleacetic Acids; Kidney Transplantation; Male; Middle Aged; Prospective Studies; Renal Insufficiency, Chronic; Tryptophan | 2020 |
RAS inhibition modulates kynurenine levels in a CKD population with and without type 2 diabetes mellitus.
Topics: Aged; Aged, 80 and over; Angiotensins; Correlation of Data; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Kynurenine; Male; Renal Insufficiency, Chronic; Renin; Tryptophan | 2020 |
Maternal Tryptophan Supplementation Protects Adult Rat Offspring against Hypertension Programmed by Maternal Chronic Kidney Disease: Implication of Tryptophan-Metabolizing Microbiome and Aryl Hydrocarbon Receptor.
Topics: Animals; Antidepressive Agents, Second-Generation; Dietary Supplements; Female; Gastrointestinal Microbiome; Hypertension; Male; Maternal Exposure; Pregnancy; Prenatal Exposure Delayed Effects; Protective Agents; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon; Renal Insufficiency, Chronic; Tryptophan | 2020 |
The relationship between blood metabolites of the tryptophan pathway and kidney function: a bidirectional Mendelian randomization analysis.
Topics: Biomarkers; Disease Progression; Glomerular Filtration Rate; Humans; Indican; Indoles; Kynurenine; Mendelian Randomization Analysis; Renal Insufficiency, Chronic; Tryptophan | 2020 |
Modulation of the Paracrine Kynurenic System in Bone as a New Regulator of Osteoblastogenesis and Bone Mineral Status in an Animal Model of Chronic Kidney Disease Treated with LP533401.
Topics: Animals; Bone Diseases, Metabolic; Calcification, Physiologic; Kynurenine; Male; Mice; Osteoblasts; Osteogenesis; Paracrine Communication; Pyrimidines; Rats; Rats, Wistar; Renal Insufficiency, Chronic; Serotonin; Serotonin Agents; Tryptophan; Tryptophan Oxygenase; Vitamin D | 2020 |
Targeting the gut microbial metabolic pathway with small molecules decreases uremic toxin production.
Topics: Animals; Bacteria; Electron Transport; Electron Transport Complex I; Escherichia coli; Flavonoids; Gastrointestinal Microbiome; Glycosides; Glycosylation; Humans; Indican; Indoles; Metabolic Networks and Pathways; Mice; Mice, Inbred C57BL; Proton-Motive Force; Quercetin; Rats; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; Structure-Activity Relationship; Toxins, Biological; Tryptophan | 2020 |
Bupi Yishen formula attenuates kidney injury in 5/6 nephrectomized rats via the tryptophan-kynurenic acid-aryl hydrocarbon receptor pathway.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Drugs, Chinese Herbal; Inflammation; Kidney; Kynurenic Acid; Medicine, Chinese Traditional; Metabolome; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon; Renal Insufficiency, Chronic; Tryptophan | 2021 |
From Discovery to Translation: Characterization of C-Mannosyltryptophan and Pseudouridine as Markers of Kidney Function.
Topics: Adult; Biomarkers; Case-Control Studies; Creatinine; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Glomerular Filtration Rate; Humans; Kidney Function Tests; Male; Middle Aged; Prospective Studies; Pseudouridine; Reference Values; Renal Insufficiency, Chronic; Tryptophan | 2017 |
Serum 6-Bromotryptophan Levels Identified as a Risk Factor for CKD Progression.
Topics: Adult; Aged; Alleles; Apolipoprotein L1; Biomarkers; Black or African American; Cohort Studies; Disease Progression; Female; Genotype; Humans; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Renal Insufficiency, Chronic; Risk Factors; Tryptophan; White People | 2018 |
Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan.
Topics: Acetylcarnitine; Animals; Canavanine; Carnitine; Case-Control Studies; Disease Models, Animal; Disease Progression; Fibrosis; Gene Knock-In Techniques; Gene Knockdown Techniques; Humans; I-kappa B Proteins; Inflammation; Kelch-Like ECH-Associated Protein 1; Kidney; Metabolomics; Mice; NF-E2-Related Factor 2; NF-kappa B; Renal Insufficiency, Chronic; Severity of Illness Index; Signal Transduction; Taurine; Tryptophan; Tryptophan Hydroxylase; Ureteral Obstruction | 2019 |
Effect of quinolinic acid - A uremic toxin from tryptophan metabolism - On hemostatic profile in rat and mouse thrombosis models.
Topics: Animals; Fibrinolysis; Hemostasis; Male; Mice; Quinolinic Acid; Rats; Rats, Wistar; Renal Insufficiency, Chronic; Thrombosis; Tryptophan | 2019 |
Serum levels and activity of indoleamine2,3-dioxygenase and tryptophanyl-tRNA synthetase and their association with disease severity in patients with chronic kidney disease.
Topics: Adult; Biomarkers; Case-Control Studies; Female; Glomerular Filtration Rate; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Male; Middle Aged; Renal Insufficiency, Chronic; Tryptophan; Tryptophan-tRNA Ligase | 2013 |
Simultaneous determination of plasma creatinine, uric acid, kynurenine and tryptophan by high-performance liquid chromatography: method validation and in application to the assessment of renal function.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Creatinine; Female; Humans; Hypertension; Kidney Function Tests; Kynurenine; Limit of Detection; Male; Middle Aged; Renal Insufficiency, Chronic; Tryptophan; Uric Acid | 2015 |
Tryptophan metabolism, its relation to inflammation and stress markers and association with psychological and cognitive functioning: Tasmanian Chronic Kidney Disease pilot study.
Topics: Aged; Aged, 80 and over; Anxiety; Biomarkers; Cognition; Cross-Sectional Studies; Depression; Female; Glomerular Filtration Rate; Humans; Hydrocortisone; Indican; Indoleacetic Acids; Inflammation; Kynurenic Acid; Male; Middle Aged; Neopterin; Oxidative Stress; Pilot Projects; Prospective Studies; Renal Insufficiency, Chronic; Surveys and Questionnaires; Tasmania; Tryptophan | 2016 |
Modulation of a Circulating Uremic Solute via Rational Genetic Manipulation of the Gut Microbiota.
Topics: Animal Feed; Animals; Bacteria; Bacteroides; Diet; Disease Models, Animal; Disease Progression; Gastrointestinal Microbiome; Gastrointestinal Tract; Genetic Engineering; Germ-Free Life; Humans; Indican; Indoles; Metagenome; Mice; Microbiota; Renal Insufficiency, Chronic; Toxins, Biological; Tryptophan; Tryptophanase | 2016 |
Increased indoleamine 2,3-dioxygenase (IDO) activity and elevated serum levels of tryptophan catabolites in patients with chronic kidney disease: a possible link between chronic inflammation and uraemic symptoms.
Topics: 5-Hydroxytryptophan; Adult; Aged; C-Reactive Protein; Case-Control Studies; Creatinine; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Inflammation Mediators; Kidney Failure, Chronic; Kynurenic Acid; Kynurenine; Male; Middle Aged; Prognosis; Prospective Studies; Quinolinic Acid; Receptors, Tumor Necrosis Factor, Type I; Renal Dialysis; Renal Insufficiency, Chronic; Serotonin; Tryptophan; Uremia | 2009 |