Compounds > tryptophan

tryptophan and Chronic Disease

tryptophan has been researched along with Chronic Disease in 130 studies

Research

Studies (130)

TimeframeStudies, this research(%)All Research%
pre-199058 (44.62)18.7374
1990's20 (15.38)18.2507
2000's20 (15.38)29.6817
2010's22 (16.92)24.3611
2020's10 (7.69)2.80

Authors

AuthorsStudies
Ayada, I; Bakkali, A; Benninga, MA; Claesen, J; de Boer, NKH; de Meij, TGJ; Jagt, JZ; Jansen, EEW; Struys, EA; van Limbergen, JE1
Bos, S; Bossuyt, P; Cremer, A; De Vos, M; Dewint, P; Dewit, O; Ferrante, M; Gonzales, GB; Holvoet, T; Lambrecht, G; Laukens, D; Lobatón, T; Louis, E; Muls, V; Peeters, A; Peeters, H; Pouillon, L; Rahier, JF; Truyens, M; Vandermeulen, L; Vermeire, S1
Deyn, PP; Kema, IP; Naudé, PJW; Nollen, EA; Sorgdrager, FJH1
Achasova, KM; Babochkina, TI; Borisova, MA; Kozhevnikova, EN; Litvinova, EA; Pindyurin, AV; Snytnikova, OA; Tsentalovich, YP1
Bigot, M; Chevalier, G; Eberl, G; Katsimpardi, L; Lledo, PM; Moigneu, C; Saha, S; Siopi, E1
Chang, Q; Gan, L; Jiang, N; Li, CC; Liu, XM; Pan, RL; Zhao, MJ1
Abadir, PM; Chung, T; de Cabo, R; Ferrucci, L; Hoke, A; Joca, H; Khadeer, M; Le, A; Lovett, J; Moaddel, R; Tian, J; Walston, J; Ward, C; Westbrook, R; Xue, QL; Yang, H1
Białek, K; Bijak, M; Czarny, P; Gruca, P; Jóźwiak, P; Papp, M; Sliwinski, T; Synowiec, E; Szemraj, J; Wigner, P2
Abreu, K; Cao, Q; Cheng, J; Chitaman, JM; Dietz, DM; Duffney, LJ; Feng, J; Jasrotia, RS; Liu, A; Pang, X; Waddell, NJ; Wang, ZJ; Wei, J; Yan, Z; Zhang, J1
Braidy, N; Guillemin, GJ; Joisten, N; Ruas, JL; Zimmer, P1
Gelpi, M; Hartling, HJ; Nielsen, SD; Trøseid, M; Ueland, PM; Ullum, H1
Maeda, S; Matsuki, N; Sakai, K; Yonezawa, T1
Caso, JR; García-Bueno, B; Leza, JC; Madrigal, JLM; Martín-Hernández, D; Tendilla-Beltrán, H1
Bell, JT; Bowyer, RCE; Livshits, G; Malkin, I; Menni, C; Steves, CJ; Verdi, S; Williams, FMK1
Blauth, M; Fuchs, D; Hüfner, K; Sperner-Unterweger, B1
Dantzer, R; Kelley, KW; Lawson, MA; McCusker, RH; O'Connor, JC; Rodriguez-Zas, SL1
Anraku, M; Chuang, VT; Ishima, Y; Jinnouchi, H; Kadowaki, D; Kubota, K; Maruyama, T; Matsushita, K; Nagumo, K; Otagiri, M; Sasaki, Y; Setoyama, H; Tanaka, M; Watanabe, H; Yamada, N; Yoshida, A1
Connor, TJ; Fagan, EM; Gibney, SM; Harkin, A; O'Byrne, J; Waldron, AM1
Barker, CJ; Chacko, A; Huston, WM; Timms, P1
Ballesteros, I; Cuartero, MI; de la Parra, J; García-Culebras, A; Lizasoain, I; Moro, MÁ1
Abdelmoaty, S; Bhat, M; Dahl, ML; Engberg, G; Erhardt, S; Finn, A; Kegel, ME; Larsson, MK; Lundberg, K; Orhan, F; Samuelsson, M; Schuppe-Koistinen, I; Schwieler, L; Sellgren, C; Skogh, E; Svensson, C1
Barone, PR; Belzung, C; Callebert, J; Guillemin, GJ; Laugeray, A; Launay, JM; Mutlu, O1
Brzozowski, T; Burnat, G; Konturek, PC; Konturek, SJ; Zopf, Y1
Greco, A; Guidobono, F; Lattuada, N; Pagani, F; Sibilia, V1
Mysliwiec, M; Pawlak, D; Pawlak, K; Tankiewicz, J1
Aparicio, M; Chauveau, P; Fouque, D1
Fuchs, D; Gluhcheva, Y; Konwalinka, G; Kurz, K; Zvetkova, E1
Chen, TC; Chong, IW; Huang, MS; Lien, CT; Lu, PL; Tasi, YM; Yang, CJ1
Barone, PR; Belzung, C; Callebert, J; Laugeray, A; Launay, JM; Surget, A1
Bercik, P; Bergonzelli, GE; Blennerhassett, P; Cherbut, C; Collins, SM; Corthesy-Theulaz, I; Foster, JA; Huang, X; Jackson, W; Khan, WI; Lu, J; Macri, J; Malinowski, P; Neufeld, KA; Potter, M; Verdu, EF1
Mandik-Nayak, L; Muller, AJ; Prendergast, GC1
Aubert, A; Barberger-Gateau, P; Capuron, L; Féart, C; Fuchs, D; Higueret, D; Layé, S; Schroecksnadel, S1
Escobar, A; Flores-Cruz, GM1
Hahm, DH; Kim, M; Kim, ST; Kwon, S; Lee, B; Lee, H; Park, HJ; Sur, BJ; Yeom, M1
Luukkainen, A; Toppila-Salmi, S1
Barth, H; Raghuraman, S1
Boivin, M; D'Souza, D; Diksic, M; Kersey, K; Kumakura, Y; Nakai, A; Rosa, P1
Kurup, PA; Kurup, RK1
Fuchs, D; Schroecksnadel, K; Wirleitner, B1
Fuchs, D; Konwalinka, G; Mattle, V; Schroecksnadel, K; Weiss, G; Winkler, C1
Le Floc'h, N; Melchior, D; Sève, B2
Cernevskis, H; Martinsons, A; Mihailova, I; Rudzite, V; Smeltere, Z1
Hecht, T; Hudson, C; Hudson, SP; MacKenzie, J1
Alcaro, MC; Bendinelli, M; Giannecchini, S; Isola, P; Papini, AM; Pistello, M; Rovero, P; Sichi, O1
Christofides, J; Darlington, LG; Egerton, M; Forrest, CM; Mackay, GM; Stone, TW; Stoy, N1
Popov, A; Schultze, JL1
Bistoni, F; D'Angelo, C; De Luca, A; Fallarino, F; Fioretti, MC; Grohmann, U; Montagnoli, C; Puccetti, P; Romani, L; Segal, BH; Vacca, C; Zelante, T1
Akhtari, M; Bragin, A; Brenker, F; Cohen, M; Engel, J; Lynch, MD; Moats, R; Vinters, HV1
Blahníková, L; Horký, J; Vojtĕchovský, M1
Marcus, R; Seltzer, S; Stoch, R1
Stein, JM; Warfield, CA1
Barker, WA; Eccleston, D1
Hirayama, C; Yoshida, K1
Hartmann, EL; Lindsley, JG; Mitchell, W1
Einhäupl, K; Hippius, H; Hoff, P; Nedopil, N; Oefele, K; Rüther, E; Steinberg, R1
Hartmann, E; Lindsley, JG; Spinweber, C1
Hedaya, RJ1
Schneider-Helmert, D1
Belendiuk, GW; Belendiuk, K; Crayton, JW; Freedman, DX1
Borisenko, KK; Guseĭnova, RS1
Arend, RA; Brown, RR; Byrne, GI; Kalayoglu, MV; Meyer, KC; Rosenthal, NS1
Bengtsson, F; Bergqvist, PB; Bosman, DK; Chamuleau, RA; Hjorth, S; Maas, MA; Vogels, BA1
Apelqvist, G; Bengtsson, F; Bergqvist, PB; Bugge, M; Wachter, H; Werner, ER1
al Mardini, H; Bartlett, K; Harrison, EJ; Ince, PG; Record, CO1
Berg, PA; Klein, R1
Bartko, JJ; Freedman, R; Gamache, PH; Gerhardt, GA; Issa, F; Kirch, DG; Lynch, M; Suddath, RL; Wyatt, RJ1
Demisch, L; Engelhardt, W; Fischer, PA; Ott, M1
Heininger, K1
Arango, V; Fontenot, MB; Kaplan, JR; Mann, JJ; Manuck, SB1
Apelqvist, G; Bengtsson, F; Bergqvist, PB; Hjorth, S1
Cangiano, C; Cascino, A; Laviano, A; Muscaritoli, M; Preziosa, I; Rossi Fanelli, F1
Branigan, PJ; Drommer, W; Gérard, HC; Hudson, AP; Koehler, L; Nettelnbreker, E; Ott, N; Schumacher, HR; Zeidler, H1
Bonerandi, JJ; Giravalli, P; Grob, JJ; Hesse, S; Jeanningros, R; Noe, C; Richard, MA; Serres, F1
Falkenhagen, D; Gerner, FJ; Linsberger, I; Schoenhofen, M; Schrefl, A; Strobl, W; Vogt, G1
Bratslavska, O; Fuchs, D; Groma, V; Martinsons, A; Rudzite, V; Widner, B1
Ashur, Y; Berry, EM; Ilan, Y; Sasson, O; Sobol, T1
Baker, HF; Cross, AJ; Crow, TJ; Glover, V; Joseph, MH; Killpack, WS; Lofthouse, R; Longden, A; Owen, F; Riley, GJ1
Chan, W; Kopple, JD; Siassi, F; Swendseid, ME; Tam, CF; Vyhmeister, I; Wang, M1
Guseĭnova, RS1
Kopple, JD; Siassi, F; Swendseid, ME; Wang, M1
Ax, AF; Frohman, CE; Gorham, JC; Novelly, RA1
Davis, M; Labadarios, D; Rossouw, JE; Williams, R1
Gillin, JC; Kaplan, JA; Wyatt, RJ1
Shastin, NN; Vilenchuk, RE1
Doust, JW; Huszka, L; Zabek, DH1
Bender, DA; Gruzelier, J; Hammond, N; Pigache, RM1
Bennert, KW; Cooper, GS; De Schryver-Kecskemeti, K; Yang, P1
Gregersen, PK; Gruber, BL; Kaufman, LD1
Haze, JJ1
Eccleston, D; Ferrier, IN; Moore, PB; Wood, KA1
Gon, J; Kitano, T; Maeda, H; Nakagawa, T; Nakamura, K; Sakuma, H; Tagami, T1
Cammisuli, S; Feurer, C; Honegger, CG; Krenger, W1
Boroń, P; Farbiszewski, R; Flisiak, R; Nowak, H; Pytel, B; Szpakowicz, T; Zimnoch, L1
Gross, AJ; McCall, D; Stockstill, JW1
Hamamoto, K; Iio, A; Itoh, H; Kataoka, M; Kawamura, M; Ohshima, K; Shimono, R; Sugawara, T; Takahashi, N; Tsuda, T1
Goodman, SI; Kleinman, JE; Korpi, ER; Wyatt, RJ1
Spinweber, CL1
Barker, WA; Eccleston, D; Scott, J1
Buzdin, VV; Ivanova, NA; Nikitina, ZS; Ryzhov, IV1
Hayakawa, T; Hoshino, M; Katagiri, K; Kawamura, Y; Miyani, M; Nakai, T; Ohnishi, H; Shiraka, S; Takeshima, A; Tsukada, K1
Hamamoto, K; Itoh, H; Shimono, R1
Bauer, J; Demisch, K; Demisch, L; Georgi, K1
Bauer, J; Demisch, K; Georgi, K1
Akamatsu, K; Hamamoto, K; Hirabayashi, S; Iio, A; Ishine, M; Itoh, H; Shimono, R; Watanabe, S1
Millinger, GS1
Bridges, PK; Hale, AS; Procter, AW1
Seltzer, S2
Frohman, CE; Gottlieb, JS; Harmison, CR1
Belokhvostova, AT; Benteleva, TA; Kliucharev, BV; Korosteleva, TA; Syromiatnikov, AA1
Aksenova, OV; Cherntsvoa, TA; Ivanova, VD1
Hardy, J; Heeley, AF; Heeley, ME; Soothill, JF1
Galushkin, IP; Pavel'eva, NI; Survillo, ON1
Cerone, G; Feriozzi, F; Mancini, GM; Murri, L; Nurzia, A1
Bamji, AN; Bender, DA1
Asafov, GB; Ekisenina, NI; Ivanova, LM; Lumel'skiĭ, VIa; Smagin, VG1
Domino, EF; Krause, RR2
Gilmour, DG; Manowitz, P; Racevskis, J1
Frosch, WA; Gilmour, DG; Manowitz, P; Shopsin, B1
Ginter, E1
Cotzias, GC; Düby, S; Ginos, J; Papavasiliou, PS; Steck, A1
Kondrat'ev, VG; Kontsevaia, NG1
Hirayama, C1
Aviram, A; Gulyassy, PF; Peters, JH1
Knapp, A; Posch, W; Wolfram, G1
Bissanti, A; Cozzolino, G; Rottini, E; Scianaro, L1

Reviews

13 review(s) available for tryptophan and Chronic Disease

ArticleYear
Tryptophan Metabolism in Inflammaging: From Biomarker to Therapeutic Target.
    Frontiers in immunology, 2019, Volume: 10

    Topics: Aging; Animals; Biomarkers; Chronic Disease; Disease Susceptibility; Humans; Immunomodulation; Inflammation; Molecular Targeted Therapy; Tryptophan

2019
The kynurenine pathway in chronic diseases: a compensatory mechanism or a driving force?
    Trends in molecular medicine, 2021, Volume: 27, Issue:10

    Topics: Chronic Disease; Humans; Kynurenic Acid; Kynurenine; Quinolinic Acid; Tryptophan

2021
Evolution to a chronic disease niche correlates with increased sensitivity to tryptophan availability for the obligate intracellular bacterium Chlamydia pneumoniae.
    Journal of bacteriology, 2014, Volume: 196, Issue:11

    Topics: Animals; Chlamydophila pneumoniae; Chronic Disease; Humans; Species Specificity; Tryptophan

2014
The Kynurenine Pathway in the Acute and Chronic Phases of Cerebral Ischemia.
    Current pharmaceutical design, 2016, Volume: 22, Issue:8

    Topics: Acute Disease; Brain Ischemia; Chronic Disease; Humans; Kynurenine; Metabolic Networks and Pathways; Tryptophan

2016
Indoleamine 2,3-dioxygenase expression is associated with chronic rhinosinusitis: review of the evidence.
    Current opinion in allergy and clinical immunology, 2013, Volume: 13, Issue:1

    Topics: Animals; Chronic Disease; Humans; Immune Tolerance; Indoleamine-Pyrrole 2,3,-Dioxygenase; Infections; Rhinitis; Sinusitis; Th2 Cells; Tryptophan

2013
Persistent infectious diseases say - IDO. Role of indoleamine-2,3-dioxygenase in disease pathogenesis and implications for therapy.
    Critical reviews in microbiology, 2014, Volume: 40, Issue:4

    Topics: Animals; Chronic Disease; Communicable Diseases; Humans; Immunomodulation; Immunotherapy; Indoleamine-Pyrrole 2,3,-Dioxygenase; Metabolic Networks and Pathways; Tryptophan

2014
IDO-expressing regulatory dendritic cells in cancer and chronic infection.
    Journal of molecular medicine (Berlin, Germany), 2008, Volume: 86, Issue:2

    Topics: Animals; Chronic Disease; Communicable Diseases; Cytokines; Dendritic Cells; Enzyme Induction; Humans; Immune Tolerance; Immunity, Cellular; Indoleamine-Pyrrole 2,3,-Dioxygenase; Neoplasms; Signal Transduction; T-Lymphocytes; Tryptophan; Tumor Escape

2008
Perspectives in the control of chronic pain by nutritional manipulation.
    Pain, 1981, Volume: 11, Issue:2

    Topics: Animals; Antidepressive Agents; Brain; Chronic Disease; Humans; Leucine; Migraine Disorders; Neurotransmitter Agents; Pain; Phenylalanine; Rats; Sensory Thresholds; Serotonin; Tryptophan

1981
[In-vitro and in-vivo studies on the selective immunoadsorption treatment of neurological diseases].
    Schriftenreihe Neurologie, 1993, Volume: 33

    Topics: Adolescent; Adult; Aged; Autoantibodies; Chronic Disease; Female; Humans; Immunosorbent Techniques; In Vitro Techniques; Male; Middle Aged; Myasthenia Gravis; Plasma Exchange; Polyneuropathies; Polyvinyl Alcohol; Receptors, Cholinergic; Tryptophan

1993
Tryptophan and secondary anorexia.
    Advances in experimental medicine and biology, 1996, Volume: 398

    Topics: Anorexia; Brain; Chronic Disease; Humans; Neoplasms; Serotonin; Tryptophan

1996
Toward an understanding of the rationale for the use of dietary supplementation for chronic pain management: the serotonin model.
    Cranio : the journal of craniomandibular practice, 1991, Volume: 9, Issue:4

    Topics: Chronic Disease; Endorphins; Enkephalins; Food, Fortified; Headache; Humans; Neurotransmitter Agents; Pain, Intractable; Serotonin; Tryptophan

1991
Neutral amino acid therapy for the management of chronic pain.
    Cranio : the journal of craniomandibular practice, 1986, Volume: 4, Issue:2

    Topics: Animals; Chronic Disease; Enkephalins; Humans; Pain; Phenylalanine; Serotonin; Transcutaneous Electric Nerve Stimulation; Tryptophan

1986
Metabolic modification of Parkinson's disease and of chronic manganese poisoning.
    Annual review of medicine, 1971, Volume: 22

    Topics: Animals; Brain; Choline; Chronic Disease; Dihydroxyphenylalanine; Drug Synergism; Humans; Manganese Poisoning; Melatonin; Methionine; Monoamine Oxidase Inhibitors; Parkinson Disease; Phenylalanine; Poisoning; Pyridoxine; Tryptophan; Tyrosine

1971

Trials

14 trial(s) available for tryptophan and Chronic Disease

ArticleYear
Effect of 5-Hydroxytryptophan on Fatigue in Quiescent Inflammatory Bowel Disease: A Randomized Controlled Trial.
    Gastroenterology, 2022, Volume: 163, Issue:5

    Topics: 5-Hydroxytryptophan; Chronic Disease; Fatigue; Humans; Inflammatory Bowel Diseases; Serotonin; Tryptophan

2022
Protein source tryptophan versus pharmaceutical grade tryptophan as an efficacious treatment for chronic insomnia.
    Nutritional neuroscience, 2005, Volume: 8, Issue:2

    Topics: Avena; Biological Availability; Blood-Brain Barrier; Chronic Disease; Cucurbita; Dietary Carbohydrates; Dietary Proteins; Double-Blind Method; Female; Humans; Male; Middle Aged; Pharmaceutical Preparations; Placebos; Seeds; Sleep; Sleep Initiation and Maintenance Disorders; Time Factors; Tryptophan; Twin Studies as Topic; Wakefulness

2005
Selectivity in response to L-tryptophan among insomniac subjects: a preliminary report.
    Sleep, 1983, Volume: 6, Issue:3

    Topics: Adolescent; Adult; Aged; Chronic Disease; Clinical Trials as Topic; Female; Flurazepam; Humans; Hypnotics and Sedatives; Male; Middle Aged; Outcome and Process Assessment, Health Care; Secobarbital; Sleep Initiation and Maintenance Disorders; Tryptophan

1983
[Chronic hyposomnias in ambulatory sleep care service].
    Der Nervenarzt, 1984, Volume: 55, Issue:9

    Topics: Adult; Ambulatory Care; Chronic Disease; Clinical Trials as Topic; Combined Modality Therapy; Diagnosis, Differential; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Oxprenolol; Sleep Initiation and Maintenance Disorders; Sleep Stages; Tryptophan

1984
Chronic insomnia: effects of tryptophan, flurazepam, secobarbital, and placebo.
    Psychopharmacology, 1983, Volume: 80, Issue:2

    Topics: Adult; Chronic Disease; Clinical Trials as Topic; Female; Flurazepam; Humans; Male; Placebos; Secobarbital; Sleep; Sleep Initiation and Maintenance Disorders; Time Factors; Tryptophan

1983
Interval therapy with L-tryptophan in severe chronic insomniacs. A predictive laboratory study.
    International pharmacopsychiatry, 1981, Volume: 16, Issue:3

    Topics: Adult; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; MMPI; Placebos; Sleep Initiation and Maintenance Disorders; Tryptophan

1981
A comparative study on antibodies to nucleoli and 5-hydroxytryptamine in patients with fibromyalgia syndrome and tryptophan-induced eosinophilia-myalgia syndrome.
    The Clinical investigator, 1994, Volume: 72, Issue:7

    Topics: Acute Disease; Adult; Aged; Antibodies, Antiphospholipid; Autoantibodies; Blotting, Western; Cell Nucleolus; Chronic Disease; Eosinophilia-Myalgia Syndrome; Female; Fibromyalgia; Follow-Up Studies; G(M1) Ganglioside; Humans; Male; Middle Aged; Serotonin; Tryptophan

1994
A multidimensional approach to analysis of cerebrospinal fluid biogenic amines in schizophrenia: I. Comparisons with healthy control subjects and neuroleptic-treated/unmedicated pairs analyses.
    Psychiatry research, 1994, Volume: 52, Issue:3

    Topics: Adult; Biogenic Amines; Chromatography, High Pressure Liquid; Chronic Disease; Dopamine; Double-Blind Method; Female; Haloperidol; Humans; Kynurenine; Male; Norepinephrine; Schizophrenia; Schizophrenic Psychology; Serotonin; Tryptophan; Tyrosine

1994
A balanced 5:1 carbohydrate:protein diet: a new method for supplementing protein to patients with chronic liver disease.
    Journal of gastroenterology and hepatology, 2000, Volume: 15, Issue:12

    Topics: Adult; Amino Acids; Amino Acids, Branched-Chain; Behavior; Blood Glucose; Chronic Disease; Dietary Carbohydrates; Dietary Proteins; Female; Humans; Insulin; Liver Diseases; Male; Middle Aged; Tryptophan; Tyrosine

2000
Clinical effects of tryptophan in chronic schizophrenic patients.
    Biological psychiatry, 1976, Volume: 11, Issue:5

    Topics: Adult; Chronic Disease; Clinical Trials as Topic; Drug Evaluation; Humans; Male; Placebos; Pyridoxine; Schizophrenia; Tryptophan

1976
L-tryptophan administered to chronic sleep-onset insomniacs: late-appearing reduction of sleep latency.
    Psychopharmacology, 1986, Volume: 90, Issue:2

    Topics: Adult; Arousal; Chronic Disease; Electroencephalography; Emotions; Heart Rate; Humans; Male; Psychomotor Performance; Sleep; Sleep Initiation and Maintenance Disorders; Tryptophan

1986
The Newcastle chronic depression study: results of a treatment regime.
    International clinical psychopharmacology, 1987, Volume: 2, Issue:3

    Topics: Adult; Behavior Therapy; Cardiovascular Diseases; Chronic Disease; Cognition; Combined Modality Therapy; Depressive Disorder; Drug Therapy, Combination; Female; Humans; Lithium; Lithium Carbonate; Male; Middle Aged; Phenelzine; Tryptophan; Vanadium

1987
Treatment of severe chronic insomnia with L-tryptophan: results of a double-blind cross-over study.
    Pharmacopsychiatry, 1987, Volume: 20, Issue:6

    Topics: Adult; Aged; Chronic Disease; Double-Blind Method; Female; Humans; Male; Middle Aged; Sleep Initiation and Maintenance Disorders; Tryptophan

1987
Free and bound serum tryptophan in drug-free normal controls and chronic schizophrenic patients.
    Biological psychiatry, 1974, Volume: 8, Issue:3

    Topics: Adult; Chronic Disease; Clinical Trials as Topic; Drug Tolerance; Fasting; Fluorometry; Humans; Male; Middle Aged; Protein Binding; Schizophrenia; Time Factors; Tryptophan

1974

Other Studies

103 other study(ies) available for tryptophan and Chronic Disease

ArticleYear
Fecal Amino Acid Analysis in Newly Diagnosed Pediatric Inflammatory Bowel Disease: A Multicenter Case-Control Study.
    Inflammatory bowel diseases, 2022, 05-04, Volume: 28, Issue:5

    Topics: Amino Acids; Case-Control Studies; Child; Chronic Disease; Colitis, Ulcerative; Crohn Disease; Feces; Histidine; Humans; Inflammatory Bowel Diseases; Tryptophan; Valine

2022
Fucose Ameliorates Tryptophan Metabolism and Behavioral Abnormalities in a Mouse Model of Chronic Colitis.
    Nutrients, 2020, Feb-11, Volume: 12, Issue:2

    Topics: Animals; Behavior, Animal; Bifidobacterium; Chronic Disease; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Escherichia coli; Fucose; Gastrointestinal Microbiome; Inflammation; Intestinal Mucosa; Male; Mice, Inbred C57BL; Social Behavior; Tryptophan

2020
Changes in Gut Microbiota by Chronic Stress Impair the Efficacy of Fluoxetine.
    Cell reports, 2020, 03-17, Volume: 30, Issue:11

    Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Cell Differentiation; Chronic Disease; Depression; Fluoxetine; Gastrointestinal Microbiome; Hippocampus; Male; Mice, Inbred C57BL; Neural Stem Cells; Neurogenesis; Serotonin; Stress, Psychological; Treatment Outcome; Tryptophan

2020
Peripheral and cerebral abnormalities of the tryptophan metabolism in the depression-like rats induced by chronic unpredicted mild stress.
    Neurochemistry international, 2020, Volume: 138

    Topics: Animals; Cerebral Cortex; Chronic Disease; Colon; Depression; Hippocampus; Male; Rats; Rats, Sprague-Dawley; Stress, Psychological; Tryptophan

2020
Kynurenines link chronic inflammation to functional decline and physical frailty.
    JCI insight, 2020, 08-20, Volume: 5, Issue:16

    Topics: Adult; Aged; Aged, 80 and over; Animals; Arginine; Chronic Disease; Cytokines; Disease Models, Animal; Female; Frail Elderly; Humans; Inflammation; Interleukin-10; Kynurenine; Male; Mice, Inbred C57BL; Middle Aged; Neuromuscular Junction; Serotonin; Tryptophan; Walking Speed; Young Adult

2020
The Impact of Chronic Mild Stress and Agomelatine Treatment on the Expression Level and Methylation Status of Genes Involved in Tryptophan Catabolic Pathway in PBMCs and Brain Structures.
    Genes, 2020, 09-18, Volume: 11, Issue:9

    Topics: Acetamides; Acetyltransferases; Animals; Brain; Chronic Disease; DNA Methylation; Gene Expression Regulation; Hypnotics and Sedatives; Indoleamine-Pyrrole 2,3,-Dioxygenase; Leukocytes, Mononuclear; Male; Rats; Rats, Wistar; Stress, Psychological; Tryptophan; Tryptophan Hydroxylase

2020
DNA Methyltransferase 3A Is Involved in the Sustained Effects of Chronic Stress on Synaptic Functions and Behaviors.
    Cerebral cortex (New York, N.Y. : 1991), 2021, 03-05, Volume: 31, Issue:4

    Topics: Animals; Chronic Disease; DNA Methyltransferase 3A; Exploratory Behavior; Locomotion; Male; Mice; Phthalimides; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Stress, Psychological; Synapses; Tryptophan

2021
The Effect of Chronic Mild Stress and Escitalopram on the Expression and Methylation Levels of Genes Involved in the Oxidative and Nitrosative Stresses as Well as Tryptophan Catabolites Pathway in the Blood and Brain Structures.
    International journal of molecular sciences, 2020, Dec-22, Volume: 22, Issue:1

    Topics: Animals; Antidepressive Agents, Second-Generation; Brain; Catalase; Chronic Disease; Citalopram; Depression; DNA Methylation; Gene Expression Regulation; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Leukocytes, Mononuclear; Male; Metabolic Networks and Pathways; Nitric Oxide Synthase Type I; Nitrosative Stress; Oxidative Stress; Rats, Wistar; Stress, Psychological; Tryptophan; Tryptophan Hydroxylase

2020
Tryptophan catabolism and immune activation in primary and chronic HIV infection.
    BMC infectious diseases, 2017, 05-16, Volume: 17, Issue:1

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Chronic Disease; Female; HIV Infections; Humans; Kynurenine; Male; Middle Aged; Prospective Studies; Tryptophan

2017
Decreased plasma amino acid concentrations in cats with chronic gastrointestinal diseases and their possible contribution in the inflammatory response.
    Veterinary immunology and immunopathology, 2018, Volume: 195

    Topics: Amino Acids; Animals; Cat Diseases; Cats; Chronic Disease; Female; Gastrointestinal Diseases; Histidine; Inflammation; Interleukin-8; Macrophages; Male; Tryptophan

2018
Chronic Mild Stress Alters Kynurenine Pathways Changing the Glutamate Neurotransmission in Frontal Cortex of Rats.
    Molecular neurobiology, 2019, Volume: 56, Issue:1

    Topics: Animals; Antidepressive Agents; Chronic Disease; Cytokines; Frontal Lobe; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation Mediators; Kynurenic Acid; Kynurenine; Male; Metabolic Networks and Pathways; Quinolinic Acid; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Stress, Psychological; Synaptic Transmission; Tryptophan

2019
Multi-OMICS analyses of frailty and chronic widespread musculoskeletal pain suggest involvement of shared neurological pathways.
    Pain, 2018, Volume: 159, Issue:12

    Topics: Absorptiometry, Photon; Adolescent; Adult; Aged; Chronic Disease; Computational Biology; Epigenomics; Female; Frailty; Genome; Genome-Wide Association Study; Glycine; Humans; Metabolomics; Middle Aged; Musculoskeletal Pain; Severity of Illness Index; Surveys and Questionnaires; Tryptophan; Uridine; Young Adult

2018
How acute and chronic physical disease may influence mental health - An Analysis of neurotransmitter precursor amino acid levels.
    Psychoneuroendocrinology, 2019, Volume: 106

    Topics: Acute Disease; Adult; Aged; Amino Acids; Anxiety Disorders; C-Reactive Protein; Chronic Disease; Depression; Depressive Disorder; Female; Humans; Inflammation; Kynurenine; Male; Mental Disorders; Mental Health; Middle Aged; Neurotransmitter Agents; Phenylalanine; Prospective Studies; Tryptophan; Tyrosine

2019
Aging leads to prolonged duration of inflammation-induced depression-like behavior caused by Bacillus Calmette-Guérin.
    Brain, behavior, and immunity, 2013, Volume: 32

    Topics: Aging; Anhedonia; Animals; Behavior, Animal; Body Weight; Chronic Disease; Depression; Hindlimb Suspension; Illness Behavior; Inflammation; Kynurenine; Lung; Mice; Mice, Inbred BALB C; Motor Activity; Mycobacterium bovis; Mycobacterium Infections; Spleen; Tryptophan

2013
Cys34-cysteinylated human serum albumin is a sensitive plasma marker in oxidative stress-related chronic diseases.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Aged; Amino Acids, Branched-Chain; Bilirubin; Biomarkers; Chronic Disease; Cysteine; Diabetes Mellitus; Diazepam; Female; Glycation End Products, Advanced; Humans; Liver Cirrhosis; Male; Middle Aged; Models, Molecular; Oxidation-Reduction; Oxidative Stress; Protein Binding; Renal Insufficiency; Serum Albumin; Spectrometry, Mass, Electrospray Ionization; Tryptophan; Warfarin

2014
Inhibition of stress-induced hepatic tryptophan 2,3-dioxygenase exhibits antidepressant activity in an animal model of depressive behaviour.
    The international journal of neuropsychopharmacology, 2014, Volume: 17, Issue:6

    Topics: Allopurinol; Animals; Antidepressive Agents; Cerebral Cortex; Chronic Disease; Corticosterone; Depressive Disorder; Disease Models, Animal; Enzyme Inhibitors; Kynurenine; Liver; Male; Neuropsychological Tests; Rats, Sprague-Dawley; Restraint, Physical; RNA, Messenger; Stress, Psychological; Tryptophan; Tryptophan Oxygenase; Weight Gain

2014
Increased levels of IL-6 in the cerebrospinal fluid of patients with chronic schizophrenia--significance for activation of the kynurenine pathway.
    Journal of psychiatry & neuroscience : JPN, 2015, Volume: 40, Issue:2

    Topics: Adult; Astrocytes; Cells, Cultured; Cerebral Cortex; Chronic Disease; Female; Humans; Interleukin-6; Interleukin-8; Kynurenic Acid; Kynurenine; Male; Middle Aged; Schizophrenia; Tryptophan; Young Adult

2015
Chronic Treatment with the IDO1 Inhibitor 1-Methyl-D-Tryptophan Minimizes the Behavioural and Biochemical Abnormalities Induced by Unpredictable Chronic Mild Stress in Mice - Comparison with Fluoxetine.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: Animals; Antidepressive Agents, Second-Generation; Chronic Disease; Cytokines; Depression; Fluoxetine; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation Mediators; Kynurenine; Male; Mice, Inbred BALB C; Signal Transduction; Stress, Psychological; Time Factors; Tryptophan

2016
Tryptophan free diet delays healing of chronic gastric ulcers in rat.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2008, Volume: 59 Suppl 2

    Topics: Animals; Anti-Ulcer Agents; Blotting, Western; Chronic Disease; Cyclooxygenase 2; Diet; Gastric Mucosa; Heat-Shock Proteins; Male; Melatonin; NF-kappa B; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Stomach Ulcer; Tryptophan; Tumor Necrosis Factor-alpha

2008
Linking chronic tryptophan deficiency with impaired bone metabolism and reduced bone accrual in growing rats.
    Journal of cellular biochemistry, 2009, Aug-01, Volume: 107, Issue:5

    Topics: Absorptiometry, Photon; Amino Acids; Animals; Body Weight; Bone and Bones; Bone Development; Bone Remodeling; Chronic Disease; Diet; Feeding Behavior; Femur; Hydroxyindoleacetic Acid; Insulin-Like Growth Factor I; Male; Rats; Rats, Sprague-Dawley; Tibia; Tomography, X-Ray Computed; Tryptophan

2009
Tissue factor/its pathway inhibitor system and kynurenines in chronic kidney disease patients on conservative treatment.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2009, Volume: 20, Issue:7

    Topics: Adult; Aged; Case-Control Studies; Chronic Disease; Female; Humans; Kidney Diseases; Kynurenine; Lipoproteins; Male; Middle Aged; Thromboplastin; Tryptophan

2009
Effect of a very low-protein diet on long-term outcomes.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2009, Volume: 54, Issue:1

    Topics: Chronic Disease; Diet, Protein-Restricted; Humans; Indican; Kidney Diseases; Prognosis; Treatment Outcome; Tryptophan

2009
Interferon-gamma-mediated pathways are induced in human CD34(+) haematopoietic stem cells.
    Immunobiology, 2010, Volume: 215, Issue:6

    Topics: Anemia; Antigens, CD34; Antiviral Agents; Cell Culture Techniques; Cell Proliferation; Cells, Cultured; Chronic Disease; Dose-Response Relationship, Drug; Erythroid Precursor Cells; Erythropoiesis; GTP Cyclohydrolase; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Monocytes; Neopterin; Tryptophan

2010
Chronic kidney disease is a potential risk factor for the development of purple urine bag syndrome.
    Journal of the American Geriatrics Society, 2009, Volume: 57, Issue:10

    Topics: Aged; Bacterial Infections; Chronic Disease; Color; Drainage; Female; Humans; Kidney Diseases; Male; Risk Factors; Syndrome; Tryptophan; Urinary Catheterization; Urinary Tract Infections

2009
Peripheral and cerebral metabolic abnormalities of the tryptophan-kynurenine pathway in a murine model of major depression.
    Behavioural brain research, 2010, Jun-26, Volume: 210, Issue:1

    Topics: Animals; Brain; Chronic Disease; Depressive Disorder, Major; Disease Models, Animal; Hydroxyindoleacetic Acid; Kynurenine; Lung; Male; Metabolic Networks and Pathways; Mice; Mice, Inbred BALB C; Serotonin; Stress, Psychological; Tryptophan

2010
Chronic gastrointestinal inflammation induces anxiety-like behavior and alters central nervous system biochemistry in mice.
    Gastroenterology, 2010, Volume: 139, Issue:6

    Topics: Animals; Anxiety; Behavior, Animal; Brain-Derived Neurotrophic Factor; Chronic Disease; Colitis; Cytokines; Hippocampus; Kynurenine; Male; Mice; Mice, Inbred AKR; Mice, Inbred BALB C; Proteomics; RNA, Messenger; Trichuriasis; Trichuris; Tryptophan; Vagotomy; Vagus Nerve

2010
Beyond immunosuppression: reconsidering indoleamine 2,3-dioxygenase as a pathogenic element of chronic inflammation.
    Immunotherapy, 2010, Volume: 2, Issue:3

    Topics: Arthritis, Rheumatoid; Autoimmunity; Chronic Disease; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Lupus Erythematosus, Systemic; Tryptophan

2010
Chronic low-grade inflammation in elderly persons is associated with altered tryptophan and tyrosine metabolism: role in neuropsychiatric symptoms.
    Biological psychiatry, 2011, Jul-15, Volume: 70, Issue:2

    Topics: Aged; Aged, 80 and over; C-Reactive Protein; Chronic Disease; Enzyme-Linked Immunosorbent Assay; Fasting; Fatigue; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Interleukin-6; Male; Mental Disorders; Movement Disorders; Neopterin; Nitrites; Psychiatric Status Rating Scales; Sleep Wake Disorders; Tryptophan; Tyrosine

2011
Reduction of serotonergic neurons in the dorsal raphe due to chronic prenatal administration of a tryptophan-free diet.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2012, Volume: 30, Issue:2

    Topics: Animals; Animals, Newborn; Chronic Disease; Disease Models, Animal; Female; Fetal Nutrition Disorders; Food, Formulated; Male; Nervous System Malformations; Neural Inhibition; Pregnancy; Raphe Nuclei; Rats; Rats, Wistar; Serotonin; Tryptophan

2012
Modulatory effects of acupuncture on murine depression-like behavior following chronic systemic inflammation.
    Brain research, 2012, Sep-07, Volume: 1472

    Topics: Acupuncture Therapy; Animals; Behavior, Animal; Brain; Chromatography, High Pressure Liquid; Chronic Disease; Depression; Dopamine; Inflammation; Kynurenine; Male; Mice; Mice, Inbred BALB C; Motor Activity; Tryptophan

2012
Sex differences of brain serotonin synthesis in patients with irritable bowel syndrome using alpha-[11C]methyl-L-tryptophan, positron emission tomography and statistical parametric mapping.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2003, Volume: 17, Issue:3

    Topics: Adult; Brain; Chronic Disease; Colonic Diseases, Functional; Female; Free Radical Scavengers; Humans; Male; Middle Aged; Risk Factors; Serotonin; Sex Factors; Tomography, Emission-Computed; Tryptophan

2003
Hypothalamic digoxin, hemispheric chemical dominance, and addictive behavior.
    The International journal of neuroscience, 2003, Volume: 113, Issue:2

    Topics: Behavior, Addictive; Chronic Disease; Digoxin; Dopamine; Functional Laterality; Humans; Hypothalamus; Serotonin; Sodium-Potassium-Exchanging ATPase; Tryptophan; Tyrosine

2003
Anemia and congestive heart failure.
    Circulation, 2003, Aug-12, Volume: 108, Issue:6

    Topics: Anemia; Causality; Cell Division; Chronic Disease; Comorbidity; Dioxygenases; Heart Failure; Hematopoiesis; Hemoglobins; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynurenine; Neopterin; Oxygenases; Prevalence; Tryptophan

2003
Possible role of cytokine-induced tryptophan degradation in anaemia of inflammation.
    European journal of haematology, 2004, Volume: 72, Issue:2

    Topics: Aged; Aged, 80 and over; Anemia; Chronic Disease; Cytokines; Female; Humans; Inflammation; Male; Reference Values; Th1 Cells; Tryptophan

2004
Chronic lung inflammation affects plasma amino acid concentrations in pigs.
    Journal of animal science, 2004, Volume: 82, Issue:4

    Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Chronic Disease; Female; Freund's Adjuvant; Haptoglobins; Injections, Intravenous; Male; Nutritional Requirements; Pneumonia; Random Allocation; Swine; Swine Diseases; Tryptophan; Tuberculosis

2004
The influence of L-tryptophan peroral load on glomerular filtration rate in chronic glomerulonephritis and chronic renal failure.
    Advances in experimental medicine and biology, 2003, Volume: 527

    Topics: Administration, Oral; Case-Control Studies; Chronic Disease; Creatinine; Glomerular Filtration Rate; Glomerulonephritis; Humans; Kidney Failure, Chronic; Serum Albumin; Tryptophan

2003
Effects of chronic lung inflammation on tryptophan metabolism in piglets.
    Advances in experimental medicine and biology, 2003, Volume: 527

    Topics: Animals; Chronic Disease; Freund's Adjuvant; Kynurenine; Pneumonia; Sus scrofa; Swine Diseases; Tryptophan

2003
Feline immunodeficiency virus plasma load reduction by a retroinverso octapeptide reproducing the Trp-rich motif of the transmembrane glycoprotein.
    Antiviral therapy, 2005, Volume: 10, Issue:5

    Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Antiviral Agents; Cats; Cell Line, Tumor; Chronic Disease; Drug Evaluation, Preclinical; Feline Acquired Immunodeficiency Syndrome; Female; Immunodeficiency Virus, Feline; Molecular Sequence Data; Oligopeptides; Tryptophan; Viral Load

2005
National Institutes of Health State of the Science Conference statement on Manifestations and Management of Chronic Insomnia in Adults, June 13-15, 2005.
    Sleep, 2005, Volume: 28, Issue:9

    Topics: Adult; Antidepressive Agents; Benzodiazepines; Chronic Disease; Cognition Disorders; Cognitive Behavioral Therapy; Comorbidity; Cost of Illness; Depression; Humans; Incidence; Prevalence; Sleep Initiation and Maintenance Disorders; Tryptophan

2005
Tryptophan metabolism and oxidative stress in patients with chronic brain injury.
    European journal of neurology, 2006, Volume: 13, Issue:1

    Topics: Adult; Aged; Brain Injuries; Chromatography, High Pressure Liquid; Chronic Disease; Enzyme-Linked Immunosorbent Assay; Female; Gas Chromatography-Mass Spectrometry; Humans; Kynurenine; Lipid Peroxidation; Male; Middle Aged; Models, Chemical; Neopterin; Nerve Growth Factors; Oxidative Stress; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Time Factors; Tryptophan

2006
Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease.
    Nature, 2008, Jan-10, Volume: 451, Issue:7175

    Topics: Animals; Aspergillosis; Aspergillus fumigatus; Chronic Disease; Disease Models, Animal; Granulomatous Disease, Chronic; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Interferon-gamma; Interleukin-17; Kynurenine; Lung; Lung Diseases, Fungal; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Reactive Oxygen Species; Receptors, Antigen, T-Cell, gamma-delta; Superoxides; T-Lymphocytes; Tryptophan

2008
Functionalized magnetonanoparticles for MRI diagnosis and localization in epilepsy.
    Epilepsia, 2008, Volume: 49, Issue:8

    Topics: Acute Disease; Animals; Blood-Brain Barrier; Chronic Disease; Densitometry; Epilepsy, Temporal Lobe; Glial Fibrillary Acidic Protein; Magnetic Resonance Imaging; Magnetics; Magnetoencephalography; Metal Nanoparticles; Rats; Tryptophan

2008
[Contribution on EEG changes in chronic liver diseases].
    Gastroenterologia, 1967, Volume: 108, Issue:3

    Topics: Anabolic Agents; Brain; Chlortetracycline; Chronic Disease; Dietary Proteins; Electroencephalography; Humans; Liver Cirrhosis; Liver Diseases; Sleep; Tryptophan

1967
The nutritional treatment of pain.
    Hospital practice (Office ed.), 1983, Volume: 18, Issue:7

    Topics: Adult; Brain Chemistry; Chronic Disease; Female; Humans; Male; Neurotransmitter Agents; Pain; Serotonin; Tryptophan

1983
The treatment of chronic depression. An illustrative case.
    The British journal of psychiatry : the journal of mental science, 1984, Volume: 144

    Topics: Carbamazepine; Chronic Disease; Depressive Disorder; Drug Therapy, Combination; Female; Humans; Lithium; Middle Aged; Phenelzine; Tranylcypromine; Tryptophan; Zimeldine

1984
Clinical evaluation of serum levels of tryptophan in hepatobiliary disease.
    Clinica chimica acta; international journal of clinical chemistry, 1980, Feb-28, Volume: 101, Issue:2-3

    Topics: Acute Disease; Adult; Aged; Bile Duct Neoplasms; Biliary Tract Diseases; Carcinoma, Hepatocellular; Cholestasis; Chronic Disease; Fatty Acids, Nonesterified; Hepatic Encephalopathy; Hepatitis; Humans; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Middle Aged; Pancreatic Neoplasms; Serum Albumin; Tryptophan

1980
Pharmacokinetic factors in the clinical use of tryptophan.
    Journal of clinical psychopharmacology, 1984, Volume: 4, Issue:6

    Topics: Adult; Chronic Disease; Cyclothymic Disorder; Depressive Disorder; Diet; Female; Half-Life; Humans; Kinetics; Pain; Tryptophan

1984
Blood tryptophan metabolism in chronic schizophrenics.
    Archives of general psychiatry, 1981, Volume: 38, Issue:6

    Topics: Adult; Blood Platelets; Chronic Disease; Humans; Male; Monoamine Oxidase; Oxidoreductases Acting on CH-NH Group Donors; Schizophrenia; Schizophrenia, Paranoid; Serotonin; Tryptophan

1981
[Tryptophan metabolism in psoriasis].
    Vestnik dermatologii i venerologii, 1981, Issue:9

    Topics: Adult; Chronic Disease; Circadian Rhythm; Female; Humans; Kynurenine; Male; Middle Aged; Psoriasis; Tryptophan; Xanthurenates

1981
Tryptophan metabolism in chronic inflammatory lung disease.
    The Journal of laboratory and clinical medicine, 1995, Volume: 126, Issue:6

    Topics: Actins; Adult; Bronchoalveolar Lavage Fluid; Chromatography, High Pressure Liquid; Chronic Disease; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Leukocyte Count; Lung Diseases, Interstitial; Macrophages; Male; Middle Aged; RNA, Messenger; Sarcoidosis; Smoking; Synovitis; Tryptophan; Tryptophan Oxygenase

1995
Neocortical dialysate monoamines of rats after acute, subacute, and chronic liver shunt.
    Journal of neurochemistry, 1995, Volume: 64, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acute Disease; Amino Acids; Ammonia; Animals; Biogenic Monoamines; Body Weight; Cerebral Cortex; Chronic Disease; Dialysis; Disease Models, Animal; Dopamine; Extracellular Space; Hepatic Encephalopathy; Hydroxyindoleacetic Acid; Male; Norepinephrine; Phenylalanine; Rats; Rats, Wistar; Serotonin; Tryptophan; Tyrosine

1995
Brain biopterin metabolism in chronic experimental hepatic encephalopathy.
    Metabolic brain disease, 1995, Volume: 10, Issue:2

    Topics: Animals; Biopterins; Body Weight; Brain Chemistry; Chronic Disease; Exploratory Behavior; GTP Cyclohydrolase; Hepatic Encephalopathy; Male; Motor Activity; Organ Size; Rats; Rats, Sprague-Dawley; Serotonin; Tryptophan

1995
Brain indoles in human hepatic encephalopathy.
    Hepatology (Baltimore, Md.), 1993, Volume: 17, Issue:6

    Topics: 5-Hydroxytryptophan; Adult; Aged; Brain; Chronic Disease; Female; Hepatic Encephalopathy; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Indoles; Liver Diseases; Male; Middle Aged; Protein Precursors; Serotonin; Tissue Distribution; Tryptophan

1993
Interleukin-2, soluble interleukin-2-receptor, neopterin, L-tryptophan and beta 2-microglobulin levels in CSF and serum of patients with relapsing-remitting or chronic-progressive multiple sclerosis.
    Journal of neurology, 1993, Volume: 241, Issue:2

    Topics: Acute Disease; Adult; beta 2-Microglobulin; Biomarkers; Biopterins; Blood Proteins; Cerebrospinal Fluid Proteins; Chronic Disease; Female; Humans; Interleukin-2; Male; Middle Aged; Multiple Sclerosis; Neopterin; Receptors, Interleukin-2; Recurrence; Sensitivity and Specificity; Tryptophan

1993
Long-term effects of chronic social stress on serotonergic indices in the prefrontal cortex of adult male cynomolgus macaques.
    Brain research, 1995, Dec-24, Volume: 705, Issue:1-2

    Topics: Animals; Biogenic Monoamines; Chronic Disease; Dopamine; Hydroxyindoleacetic Acid; Macaca fascicularis; Male; Prefrontal Cortex; Serotonin; Social Behavior; Stress, Physiological; Time Factors; Tryptophan

1995
Acute effects of L-tryptophan on brain extracellular 5-HT and 5-HIAA levels in chronic experimental portal-systemic encephalopathy.
    Metabolic brain disease, 1996, Volume: 11, Issue:3

    Topics: Animals; Brain Chemistry; Chronic Disease; Extracellular Space; Hepatic Encephalopathy; Hydroxyindoleacetic Acid; Male; Microdialysis; Portacaval Shunt, Surgical; Portal System; Rats; Rats, Sprague-Dawley; Serotonin; Tryptophan

1996
Ultrastructural and molecular analyses of the persistence of Chlamydia trachomatis (serovar K) in human monocytes.
    Microbial pathogenesis, 1997, Volume: 22, Issue:3

    Topics: Antibodies, Blocking; Bacterial Outer Membrane Proteins; Cell Membrane; Cells, Cultured; Chlamydia Infections; Chlamydia trachomatis; Chronic Disease; Cytoplasm; DNA, Bacterial; Humans; Interferon-alpha; Interferon-gamma; Lipopolysaccharides; Microscopy, Electron; Microscopy, Immunoelectron; Monocytes; Polymerase Chain Reaction; RNA, Bacterial; RNA, Transfer; Transcription, Genetic; Tryptophan; Tumor Necrosis Factor-alpha

1997
[Plasma tryptophan bioavailability during chronic urticaria].
    Annales de dermatologie et de venereologie, 1998, Volume: 125, Issue:3

    Topics: Adolescent; Adult; Biological Availability; Biological Transport; Biomarkers; Brain Chemistry; Case-Control Studies; Chronic Disease; Erythrocytes; Female; Homeostasis; Humans; Male; Middle Aged; Psychological Tests; Psychoneuroimmunology; Serotonin; Tryptophan; Urticaria

1998
Fractionated plasma separation and adsorption system: a novel system for blood purification to remove albumin bound substances.
    Artificial organs, 1999, Volume: 23, Issue:1

    Topics: Acute Disease; Adsorption; Bilirubin; Biocompatible Materials; Chronic Disease; Dialysis; Equipment Design; Equipment Safety; Fibrinogen; Filtration; Hemodiafiltration; Humans; Immunoglobulin G; Immunoglobulin M; Liver Diseases; Membranes, Artificial; Molecular Weight; Polymers; Protein Binding; Serum Albumin; Sulfones; Tryptophan

1999
Kynurenine and neopterin in chronic glomerulonephritis.
    Advances in experimental medicine and biology, 1999, Volume: 467

    Topics: Biomarkers; Chronic Disease; Creatinine; Fasting; Glomerular Filtration Rate; Glomerulonephritis; Glomerulonephritis, Membranous; Humans; Immunity, Cellular; Kidney; Kidney Failure, Chronic; Kynurenine; Neopterin; Tryptophan

1999
Monoamine mechanisms in chronic schizophrenia: post-mortem neurochemical findings.
    The British journal of psychiatry : the journal of mental science, 1979, Volume: 134

    Topics: Aged; Brain Chemistry; Catechol O-Methyltransferase; Chronic Disease; Dopamine; Dopamine beta-Hydroxylase; Female; Humans; Hydroxyindoleacetic Acid; Kynurenine; Male; Monoamine Oxidase; Norepinephrine; Phenylacetates; Schizophrenia; Serotonin; Tryptophan; Tyrosine 3-Monooxygenase

1979
Amino acid metabolism in the chronically uremic rat.
    Clinical nephrology, 1975, Volume: 3, Issue:6

    Topics: Amine Oxidase (Copper-Containing); Amines; Amino Acids; Animals; Argininosuccinate Lyase; Argininosuccinate Synthase; Brain; Chronic Disease; Citrulline; Dietary Proteins; Disease Models, Animal; Hydroxyindoleacetic Acid; Kidney; Liver; Monoamine Oxidase; Multienzyme Complexes; Muscles; Myocardium; Ornithine Carbamoyltransferase; Phenylalanine; Phenylalanine Hydroxylase; Rats; Tryptophan; Tryptophan Oxygenase; Tyrosine Transaminase; Uremia

1975
[Tryptophan metabolic indices in allergic dermatoses].
    Vestnik dermatologii i venerologii, 1979, Issue:4

    Topics: Chronic Disease; Dermatitis, Atopic; Female; Humans; Kynurenic Acid; Kynurenine; Male; Prurigo; Pyridoxal Phosphate; Tryptophan; Urticaria; Xanthurenates

1979
Plasma tryptophan levels and brain serotonin metabolism in chronically uremic rats.
    The Journal of nutrition, 1977, Volume: 107, Issue:5

    Topics: Animals; Brain; Caseins; Chronic Disease; Dietary Proteins; DNA; Female; Humans; Hydroxyindoleacetic Acid; Kidney; Ligation; Nephrectomy; Rats; Renal Artery; Serotonin; Tryptophan; Uremia

1977
Classically conditioned autonomic discrimination and tryptophan uptake in chronic schizophrenia.
    Psychophysiology, 1978, Volume: 15, Issue:2

    Topics: Adult; Autonomic Nervous System; Chronic Disease; Conditioning, Classical; Discrimination Learning; Humans; Male; Schizophrenia; Tryptophan

1978
The degradation of tryptophan in severe liver disease.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1978, Volume: 48, Issue:3

    Topics: Acute Disease; Chronic Disease; Humans; Kynurenine; Liver Diseases; Tryptophan; Vitamins

1978
[Change in serotonin metabolism in chronic liver diseases].
    Terapevticheskii arkhiv, 1976, Volume: 48, Issue:3

    Topics: Chronic Disease; Hepatitis; Humans; Hydroxyindoleacetic Acid; Liver Cirrhosis; Liver Diseases; Serotonin; Tryptophan

1976
Urinary excretion of n,n-dimethylated tryptamines in chronic schizophrenia. A review of the present status of the hypothesis.
    Canadian Psychiatric Association journal, 1976, Volume: 21, Issue:8

    Topics: 5-Methoxytryptamine; Adult; Bufotenin; Chronic Disease; Epinephrine; Female; Humans; Hydroxyindoleacetic Acid; Methylation; Middle Aged; N,N-Dimethyltryptamine; Norepinephrine; Phenelzine; Schizophrenia; Serotonin; Tryptamines; Tryptophan

1976
Changes in serum tryptophan and albumin binding of tryptophan in chlorpromazine-treated chronic schizophrenics on withdrawal and restoration of drug therapy.
    Psychological medicine, 1975, Volume: 5, Issue:4

    Topics: Adult; Amino Acids; Brain; Chlorpromazine; Chronic Disease; Fatty Acids, Nonesterified; Humans; Male; Middle Aged; Placebos; Protein Binding; Schizophrenia; Serotonin; Serum Albumin; Tryptophan

1975
Gastrointestinal involvement in L-tryptophan (L-Trp) associated eosinophilia-myalgia syndrome (EMS).
    Digestive diseases and sciences, 1992, Volume: 37, Issue:5

    Topics: Biopsy; Chronic Disease; Diagnosis, Differential; Diarrhea; Digestive System; Eosinophilia-Myalgia Syndrome; Female; Gastrointestinal Diseases; Humans; Middle Aged; Tryptophan; Weight Loss

1992
Clinical follow-up and immunogenetic studies of 32 patients with eosinophilia-myalgia syndrome.
    Lancet (London, England), 1991, May-04, Volume: 337, Issue:8749

    Topics: Adult; Aged; Chronic Disease; Eosinophilia; Erythema; Female; Follow-Up Studies; HLA-DR4 Antigen; Humans; Male; Middle Aged; Muscular Diseases; Pain; Prognosis; Prospective Studies; Syndrome; Tryptophan

1991
Relapse in chronic depressives on withdrawal of L-tryptophan.
    Lancet (London, England), 1990, Aug-11, Volume: 336, Issue:8711

    Topics: Chronic Disease; Depressive Disorder; Humans; Recurrence; Tryptophan

1990
[Measurement of intrahepatic shunt using Rutland method].
    Kaku igaku. The Japanese journal of nuclear medicine, 1991, Volume: 28, Issue:1

    Topics: Chronic Disease; Hepatitis; Humans; Liver Circulation; Liver Cirrhosis; Organotechnetium Compounds; Pyridoxal; Radioisotope Renography; Tryptophan

1991
Changes of neurotransmitter systems in chronic relapsing experimental allergic encephalomyelitis in rat brain and spinal cord.
    Journal of neurochemistry, 1986, Volume: 47, Issue:4

    Topics: Animals; Brain; Chronic Disease; Dopamine; Encephalomyelitis, Autoimmune, Experimental; Female; Hydroxyindoleacetic Acid; Neurotransmitter Agents; Norepinephrine; Rats; Recurrence; Serotonin; Spinal Cord; Tissue Distribution; Tryptophan; Tyrosine

1986
[Studies of the effect of a protein-free diet and branched-chain amino acids (preparation Aminosteril-Hepa) on selected biochemical indicators in chronic experimental hepatic encephalopathy].
    Neuropatologia polska, 1989, Volume: 27, Issue:3

    Topics: Amino Acids; Amino Acids, Branched-Chain; Ammonia; Animals; Chronic Disease; Dietary Proteins; Hepatic Encephalopathy; Male; Parenteral Nutrition; Phenols; Phenylalanine; Rats; Rats, Inbred Strains; Thioacetamide; Tryptophan; Tyrosine

1989
L-tryptophan.
    Journal of the American Dental Association (1939), 1989, Volume: 119, Issue:6

    Topics: Chronic Disease; Humans; Placebos; Temporomandibular Joint Dysfunction Syndrome; Tryptophan

1989
Assessment of hepatic excretory function in chronic liver disease by hepatobiliary scintigraphy.
    Annals of nuclear medicine, 1989, Volume: 3, Issue:3

    Topics: Adolescent; Adult; Aged; Chronic Disease; Female; Humans; Liver; Liver Diseases; Liver Function Tests; Male; Middle Aged; Organotechnetium Compounds; Pyridoxal; Radionuclide Imaging; Tryptophan

1989
Neurotransmitter amino acids in post-mortem brains of chronic schizophrenic patients.
    Psychiatry research, 1987, Volume: 22, Issue:4

    Topics: Adult; Aged; Amino Acids; Amygdala; Brain Chemistry; Chronic Disease; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neurotransmitter Agents; Postmortem Changes; Schizophrenia; Tryptophan

1987
[Elevated kynurenine concentration in the blood serum of children with epilepsy and bronchial asthma].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1988, Volume: 88, Issue:6

    Topics: Adolescent; Asthma; Child; Child, Preschool; Chronic Disease; Epilepsy; Female; Humans; Kynurenine; Male; Pneumonia; Spectrophotometry; Tryptophan

1988
[The influence of ursodeoxycholic acid on hepatobiliary scintigraphy with 99mTc-N-pyridoxyl-5-methyltryptophan in chronic liver diseases].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1988, Volume: 85, Issue:11

    Topics: Adult; Biliary Tract; Chronic Disease; Deoxycholic Acid; Female; Humans; Liver; Liver Diseases; Male; Middle Aged; Organometallic Compounds; Organotechnetium Compounds; Pyridoxal; Radionuclide Imaging; Tryptophan; Ursodeoxycholic Acid

1988
Evaluation of common bile duct stenosis in chronic pancreatitis using cholescintigraphy.
    European journal of nuclear medicine, 1988, Volume: 14, Issue:3

    Topics: Adult; Aged; Chronic Disease; Common Bile Duct; Common Bile Duct Diseases; Constriction, Pathologic; Female; Humans; Male; Middle Aged; Organometallic Compounds; Organotechnetium Compounds; Pancreatitis; Pyridoxal; Radionuclide Imaging; Technetium; Tryptophan

1988
Treatment of severe chronic insomnia with L-tryptophan and varying sleeping times.
    Pharmacopsychiatry, 1987, Volume: 20, Issue:6

    Topics: Adult; Affect; Aged; Chronic Disease; Combined Modality Therapy; Female; Humans; Male; Middle Aged; Sleep; Sleep Initiation and Maintenance Disorders; Time Factors; Tryptophan

1987
[Biliary kinetic study in chronic pancreatitis using cholescintigraphy].
    Kaku igaku. The Japanese journal of nuclear medicine, 1987, Volume: 24, Issue:9

    Topics: Biliary Tract; Chronic Disease; Female; Gallbladder; Humans; Kinetics; Male; Middle Aged; Organometallic Compounds; Organotechnetium Compounds; Pancreatitis; Radionuclide Imaging; Tryptophan

1987
Clomipramine, tryptophan and lithium in combination for resistant endogenous depression: seven case studies.
    The British journal of psychiatry : the journal of mental science, 1987, Volume: 151

    Topics: Adult; Antidepressive Agents, Tricyclic; Chronic Disease; Clomipramine; Depressive Disorder; Drug Resistance; Drug Therapy, Combination; Female; Humans; Lithium; Male; Middle Aged; Tryptophan

1987
Dietary control of chronic maxillofacial pain.
    Endodontics & dental traumatology, 1985, Volume: 1, Issue:3

    Topics: Chronic Disease; Dietary Carbohydrates; Double-Blind Method; Face; Humans; Pain; Placebos; Tryptophan

1985
Pain relief by dietary manipulation and tryptophan supplements.
    Journal of endodontics, 1985, Volume: 11, Issue:10

    Topics: Chronic Disease; Facial Pain; Female; Humans; Male; Tryptophan

1985
Schizophrenia--new concepts.
    Southern medical journal, 1971, Volume: 64, Issue:6

    Topics: Alpha-Globulins; Brain; Chronic Disease; Humans; Lipoproteins; Schizophrenia; Synaptic Transmission; Tryptophan

1971
[Determination of 3-oxyanthranilic acid in the blood serum in the immunodiagnosis of precancerous changes in the mucous membrane of the urinary bladder].
    Biulleten' eksperimental'noi biologii i meditsiny, 1974, Volume: 78, Issue:12

    Topics: Adult; Aged; Carcinogens; Chronic Disease; Coloring Agents; Environmental Exposure; Humans; Immunodiffusion; Middle Aged; Occupational Diseases; ortho-Aminobenzoates; Precancerous Conditions; Tryptophan; Urinary Bladder Neoplasms

1974
[Apropos of the use of vitamins in the treatment of chronic leukemia at its early stage. II].
    Problemy gematologii i perelivaniia krovi, 1966, Volume: 11, Issue:5

    Topics: Ascorbic Acid; Chronic Disease; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Niacinamide; Pyridoxine; Riboflavin; Thiamine; Tryptophan; Vitamin B 12; Vitamin B 6 Deficiency; Vitamins

1966
A disorder of tryptophan metabolism in chronic granulomatous disease.
    Archives of disease in childhood, 1970, Volume: 45, Issue:242

    Topics: Child; Child, Preschool; Chromatography, Paper; Chronic Disease; Granuloma; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infections; Kynurenic Acid; Kynurenine; Lymphadenitis; Male; Niacinamide; Pyridoxine; Tryptophan; Xanthurenates

1970
[The mucous membrane of the small intestine in different phases of the course of non-specific ulcerative colitis].
    Arkhiv patologii, 1972, Volume: 34, Issue:10

    Topics: Chromaffin System; Chronic Disease; Colitis, Ulcerative; Glycosaminoglycans; Humans; Intestinal Mucosa; Intestine, Small; Mitosis; Recurrence; Remission, Spontaneous; Sulfhydryl Compounds; Tryptophan

1972
[Effect of tryptophan on the somatotropic hormone during sleep in schizophrenics].
    Bollettino della Societa italiana di biologia sperimentale, 1973, Dec-30, Volume: 49, Issue:24

    Topics: Adult; Chronic Disease; Circadian Rhythm; Growth Hormone; Humans; Middle Aged; Pituitary Gland; Schizophrenia; Sleep; Sleep Stages; Sleep, REM; Tryptophan

1973
Serum tryptophan binding in chlorpromazine-treated chronic schizophrenics.
    Journal of neurochemistry, 1974, Volume: 22, Issue:5

    Topics: Chlorpromazine; Chronic Disease; Diffusion; Fatty Acids, Nonesterified; Humans; Liver; Male; Orphenadrine; Protein Binding; Schizophrenia; Serum Albumin; Time Factors; Tryptophan; Tryptophan Oxygenase

1974
[Amino acid levels in the blood serum of patients with chronic colitis].
    Terapevticheskii arkhiv, 1974, Volume: 46, Issue:4

    Topics: Adult; Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Betaine; Chronic Disease; Citrulline; Colitis; Glutamates; Glutamine; Glycine; Histidine; Humans; Middle Aged; Ornithine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tryptophan; Tyrosine; Urea

1974
Plasma tryptophan tolerance curves in drug free normal controls, schizophrenic patients and prisoner volunteers.
    Journal of psychiatric research, 1974, Volume: 10, Issue:3-4

    Topics: Acute Disease; Administration, Oral; Adult; Chlorpromazine; Chronic Disease; Circadian Rhythm; Depression; Fasting; Food; Half-Life; Humans; Male; Middle Aged; Personality Disorders; Prisoners; Schizophrenia; Tryptophan

1974
Low plasma tryptophan levels in recently hospitalized schizophrenics.
    Biological psychiatry, 1973, Volume: 6, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Bipolar Disorder; Chronic Disease; Depression; Diet; Female; Hospitalization; Humans; Length of Stay; Male; Middle Aged; Phenylalanine; Racial Groups; Schizophrenia; Sex Factors; Tryptophan; Tyrosine

1973
Association of plasma tryptophan levels with clinical change in female schizophrenic patients.
    Biological psychiatry, 1973, Volume: 6, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aged; Chronic Disease; Female; Hospitalization; Humans; Length of Stay; Male; Middle Aged; Phenylalanine; Racial Groups; Remission, Spontaneous; Schizophrenia; Sex Factors; Tryptophan; Tyrosine

1973
[New biochemical conception of chronic alcoholism].
    Ceskoslovenska psychiatrie, 1973, Volume: 69, Issue:5

    Topics: Alcoholism; Biogenic Amines; Chronic Disease; Ethanol; Humans; Tryptophan; Tyrosine

1973
[Balance and metabolism of tryptophan in pneumonia].
    Terapevticheskii arkhiv, 1971, Volume: 43, Issue:5

    Topics: Adult; Chronic Disease; Focal Infection; Humans; Kynurenine; Male; Pneumonia; Spectrophotometry; Tryptophan

1971
Tryptophan metabolism in liver disease.
    Clinica chimica acta; international journal of clinical chemistry, 1971, Volume: 32, Issue:2

    Topics: Adult; Aged; Amino Acids; Ammonia; Brain Diseases; Chronic Disease; Diabetes Complications; Diabetes Mellitus; Fasting; Female; Hepatic Encephalopathy; Hepatitis; Humans; Liver Cirrhosis; Liver Function Tests; Male; Methenolone; Middle Aged; Peptic Ulcer; Prednisolone; Syphilis; Tolbutamide; Tryptophan

1971
Evaluation of amino acid and protein requirements in chronic uremia.
    Archives of internal medicine, 1970, Volume: 126, Issue:5

    Topics: Amino Acids; Biological Transport; Carbon Isotopes; Chronic Disease; Creatinine; Dietary Proteins; Glomerular Filtration Rate; Humans; Intestinal Absorption; Intestine, Small; Kidney Concentrating Ability; Nutritional Requirements; Proteins; Renal Aminoacidurias; Time Factors; Tryptophan; Uremia

1970
[Chronic urticaria and vitamin B6 dependent disorders in tryptophan metabolism].
    Dermatologische Monatschrift, 1970, Volume: 156, Issue:3

    Topics: Adolescent; Adult; Aged; Child; Chronic Disease; Female; Humans; Kynurenine; Male; Middle Aged; Pyridoxine; Tryptophan; Urticaria; Xanthurenates

1970
[Biochemical findings on tryptophan-nicotinic acid metabolism during acute and chronic hepatopathies].
    Acta vitaminologica et enzymologica, 1968, Volume: 22, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Aged; Chronic Disease; Female; Humans; Liver Diseases; Male; Middle Aged; Nicotinic Acids; Tryptophan

1968