tryptophan has been researched along with Chemical Dependence in 38 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (44.74) | 18.7374 |
| 1990's | 7 (18.42) | 18.2507 |
| 2000's | 6 (15.79) | 29.6817 |
| 2010's | 3 (7.89) | 24.3611 |
| 2020's | 5 (13.16) | 2.80 |
| Authors | Studies |
|---|---|
| Apostolopoulos, V; Davidson, M; Hossain, MK; Nurgali, K; Rashidi, N; Raza, A | 1 |
| Araos, P; Castilla-Ortega, E; Flores-López, M; García-Marchena, N; Pavón-Morón, FJ; Pedraza, C; Requena-Ocaña, N; Rodríguez de Fonseca, F; Serrano, A; Wallace, A | 1 |
| Fan, N; Lu, H; Luo, Y; Ni, X; Wen, Y; Zhang, M; Zhang, Z | 1 |
| Carrico, AW; Chahine, A; Cohn, M; Dilworth, SE; Fuchs, D; Gouse, H; Lee, J; Lee, JY; Magidson, JF; Meade, CS | 1 |
| Cisneros, IE; Cunningham, KA | 1 |
| Benkelfat, C; Booij, L; Diksic, M; Gravel, P; Leyton, M; Pihl, RO; Regoli, M; Soucy, JP; Young, SN | 1 |
| Cumming, P | 1 |
| He, W; Li, W; Song, F; Wang, D; Wang, Z; Wei, W; Xiao, Y; Yang, L; Yu, J | 1 |
| Dougherty, DA; Lester, HA; Puskar, NL; Shanata, JA; Xiu, X | 1 |
| Carhart-Harris, RL; Christmas, DM; Munafo, MR; Nutt, DJ; Wilson, SJ | 1 |
| Cook, LJ; Cooper, JD; Roiser, JP; Rubinsztein, DC; Sahakian, BJ | 1 |
| Hayakawa, K; Kato, N; Kojima, T; Nishimura, H; Ohta, H; Toriba, A; Yoshiyagawa, S | 1 |
| Brandacher, G; Fuchs, D; Hoeller, E; Weiss, HG | 1 |
| Leccese, AP; Lyness, WH | 1 |
| Badawy, AA; Evans, M; Punjani, NF | 1 |
| Aronson, SC; Black, JE; Heninger, GR; Jatlow, P; Kosten, TR; McDougle, CJ; Price, LH; Scanley, BE | 1 |
| Charney, DS; Delgado, PL; Kosten, TR; Krystal, JH; Satel, SL | 1 |
| Benkelfat, C; Dean, P; Ellenbogen, MA; Palmour, RM; Young, SN | 1 |
| Chiu, C; Comings, DE; Dietz, G; Ferry, L; Gade, R; Johnson, JP; Lesieur, HR; MacMurray, JP; Muhleman, D; Rosenthal, RJ; Rugle, L; Spence, M; Sverd, J; To, M; Winn-Deen, E; Wu, S | 1 |
| Brammer, GL; Caspi, A; Fawcett, JP; Moffitt, TE; Raleigh, M; Silva, P; Yuwiler, A | 1 |
| Van der Does, AJ | 1 |
| Kuschinsky, G | 1 |
| Huidobro, F; Huidobro-Toro, JP; Leong Way, E | 1 |
| Barthelemy, L; Degiovanni, A; Sizaret, P | 1 |
| Chadwick, MJ; Gregory, DL; Wendling, G | 1 |
| Kamei, J; Kasuya, Y; Mori, T | 1 |
| Heninger, GR; Krystal, JH; Price, LH; Ricaurte, GA | 2 |
| Comings, BG; Comings, DE; Knell, E | 1 |
| Pike, RF | 1 |
| During, MJ; Freese, A | 1 |
| Berman, ML; Tennant, F | 1 |
| Schneider-Helmert, D | 1 |
| Karacan, I; Williams, RL | 1 |
| Goodwin, FK; Post, RM | 1 |
| Oswald, I | 1 |
| Lovenberg, W; Schechter, PJ; Sjoerdsma, A | 1 |
| Gershon, ES; Shader, RI | 1 |
6 review(s) available for tryptophan and Chemical Dependence
| Article | Year |
|---|---|
Tryptophan and Substance Abuse: Mechanisms and Impact.
Topics: Animals; Behavior, Addictive; Brain; Central Nervous System Stimulants; Humans; Mammals; Methamphetamine; Substance-Related Disorders; Tryptophan | 2023 |
Covid-19 interface with drug misuse and substance use disorders.
Topics: Adaptation, Psychological; Angiotensin-Converting Enzyme 2; Animals; Axons; Comorbidity; COVID-19; Disease Susceptibility; Drug Misuse; Endothelial Cells; Humans; Immunity, Innate; Inflammation; Kynurenine; Neurons; Neurotransmitter Agents; Olfactory Mucosa; Pandemics; SARS-CoV-2; Social Isolation; Stress, Psychological; Substance-Related Disorders; Tryptophan; Viral Tropism | 2021 |
Chronic immune activation underlies morbid obesity: is IDO a key player?
Topics: Adipose Tissue; Animals; Bariatric Surgery; Ghrelin; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Leptin; Macrophages; Obesity, Morbid; Peptide Hormones; Serotonin; Substance-Related Disorders; Tryptophan; Weight Loss | 2007 |
The effects of tryptophan depletion on mood and psychiatric symptoms.
Topics: Anorexia Nervosa; Bipolar Disorder; Brain; Bulimia; Cognition Disorders; Depressive Disorder, Major; Humans; Mood Disorders; Obsessive-Compulsive Disorder; Recurrence; Serotonin; Severity of Illness Index; Substance-Related Disorders; Tryptophan | 2001 |
[Pharmacology of hypnotics].
Topics: Barbiturates; Benzodiazepines; Bromisovalum; Chloral Hydrate; Half-Life; Humans; Hypnotics and Sedatives; Methaqualone; Piperidones; Sleep; Substance-Related Disorders; Tryptophan; Urea | 1976 |
Recent developments in the diagnosis and treatment of sleep disorders.
Topics: Aged; Antidepressive Agents; Biological Clocks; Circadian Rhythm; Depressive Disorder; Drug Interactions; Electroencephalography; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Sleep; Sleep Apnea Syndromes; Sleep Initiation and Maintenance Disorders; Sleep Wake Disorders; Sleep, REM; Substance-Related Disorders; Tryptophan; United States | 1985 |
8 trial(s) available for tryptophan and Chemical Dependence
| Article | Year |
|---|---|
Tryptophan for the sleeping disorder and mental symptom of new-type drug dependence: A randomized, double-blind, placebo-controlled trial.
Topics: Adult; China; Double-Blind Method; Female; Humans; Male; Sleep Wake Disorders; Substance-Related Disorders; Surveys and Questionnaires; Treatment Outcome; Tryptophan | 2016 |
Equivalent effects of acute tryptophan depletion on REM sleep in ecstasy users and controls.
Topics: Adult; Cross-Over Studies; Double-Blind Method; Hallucinogens; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Pain Measurement; Polysomnography; Reaction Time; Sleep, REM; Substance-Related Disorders; Time Factors; Tryptophan; Young Adult | 2009 |
Serotonergic mechanisms of cocaine effects in humans.
Topics: Adult; Affect; Cocaine; Depression, Chemical; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Serotonin; Substance-Related Disorders; Time Factors; Tryptophan | 1995 |
Tryptophan depletion and attenuation of cue-induced craving for cocaine.
Topics: Adult; Amino Acids; Cocaine; Cues; Double-Blind Method; Drinking; Habituation, Psychophysiologic; Hospitalization; Humans; Male; Middle Aged; Placebos; Racial Groups; Recurrence; Serotonin; Substance Abuse, Intravenous; Substance-Related Disorders; Treatment Outcome; Tryptophan | 1995 |
Mood-lowering effect of tryptophan depletion. Enhanced susceptibility in young men at genetic risk for major affective disorders.
Topics: Adolescent; Adult; Affect; Alcoholism; Amino Acids; Depressive Disorder; Double-Blind Method; Family; Genetic Markers; Humans; Male; Phenotype; Placebos; Psychiatric Status Rating Scales; Serotonin; Substance-Related Disorders; Tryptophan | 1994 |
Whole blood serotonin relates to violence in an epidemiological study.
Topics: Adult; Alcohol Drinking; Biomarkers; Body Weight; Crime; Female; Humans; Illicit Drugs; Male; New Zealand; Platelet Count; Psychotic Disorders; Serotonin; Sex Characteristics; Smoking; Socioeconomic Factors; Substance-Related Disorders; Tryptophan; Violence | 1998 |
A double-blind amino acids, L-tryptophan and L-tyrosine, and placebo study with cocaine-dependent subjects in an inpatient chemical dependency treatment center.
Topics: Adolescent; Adult; Cocaine; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; MMPI; Substance Withdrawal Syndrome; Substance-Related Disorders; Tryptophan; Tyrosine | 1990 |
Estimation of brain amine metabolism in affective illness: cerebrospinal fluid studies utilizing probenecid.
Topics: Bipolar Disorder; Brain; Depression; Dihydroxyphenylalanine; Fenclonine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methyltyrosines; Phenylacetates; Placebos; Probenecid; Stimulation, Chemical; Substance-Related Disorders; Tryptophan | 1974 |
24 other study(ies) available for tryptophan and Chemical Dependence
| Article | Year |
|---|---|
Plasma Lysophosphatidic Acid Concentrations in Sex Differences and Psychiatric Comorbidity in Patients with Cocaine Use Disorder.
Topics: Child; Cocaine; Comorbidity; Cross-Sectional Studies; Female; Humans; Male; Sex Characteristics; Substance-Related Disorders; Tryptophan | 2023 |
Preliminary comparative analysis of kynurenine pathway metabolites in chronic ketamine users, schizophrenic patients, and healthy controls.
Topics: Adult; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Humans; Ketamine; Kynurenic Acid; Kynurenine; Male; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia; Substance-Related Disorders; Tandem Mass Spectrometry; Time Factors; Tryptophan; Young Adult | 2020 |
Tryptophan degradation is associated with risk-taking propensity in methamphetamine users with treated HIV infection.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Biotransformation; Cross-Sectional Studies; HIV Infections; Homosexuality, Male; Humans; Impulsive Behavior; Kynurenine; Male; Methamphetamine; Middle Aged; Phenylalanine; Psychological Tests; Risk-Taking; Substance-Related Disorders; Tryptophan; Tyrosine; Viral Load | 2020 |
Brain serotonin synthesis in MDMA (ecstasy) polydrug users: an alpha-[(11) C]methyl-l-tryptophan study.
Topics: Adult; Antidepressive Agents, Second-Generation; Brain; Brain Mapping; Female; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Positron-Emission Tomography; Self Report; Serotonin; Sex Factors; Substance-Related Disorders; Tryptophan; Young Adult | 2014 |
Measuring effects of MDMA (ecstasy) abuse on the rate of cerebral serotonin synthesis.
Topics: Brain; Female; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Serotonin; Substance-Related Disorders; Tryptophan | 2014 |
Nicotine binding to brain receptors requires a strong cation-pi interaction.
Topics: Acetylcholine; Animals; Binding Sites; Brain; Cations; Halogenation; Mice; Models, Molecular; Nicotine; Nicotinic Agonists; Oocytes; Organ Specificity; Protein Binding; Protein Conformation; Rats; Receptors, Nicotinic; Smoking; Substance-Related Disorders; Tryptophan; Xenopus laevis | 2009 |
Association of a functional polymorphism in the serotonin transporter gene with abnormal emotional processing in ecstasy users.
Topics: Adult; Affective Symptoms; Depressive Disorder; Diagnosis, Dual (Psychiatry); Female; Genotype; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Neuropsychological Tests; Personality Inventory; Polymorphism, Genetic; Serotonin Plasma Membrane Transport Proteins; Substance-Related Disorders; Tryptophan | 2005 |
Rapid and sensitive determination of tryptophan, serotonin and psychoactive tryptamines by thin-layer chromatography/fluorescence detection.
Topics: Chromatography, Thin Layer; Humans; Molecular Structure; Reproducibility of Results; Serotonin; Spectrometry, Fluorescence; Substance-Related Disorders; Tryptamines; Tryptophan | 2007 |
The effects of putative 5-hydroxytryptamine receptor active agents on D-amphetamine self-administration in controls and rats with 5,7-dihydroxytryptamine median forebrain bundle lesions.
Topics: 5,7-Dihydroxytryptamine; Animals; Cyproheptadine; Dextroamphetamine; Fluoxetine; Humans; Male; Medial Forebrain Bundle; Methysergide; Neural Pathways; Quipazine; Rats; Rats, Inbred Strains; Serotonin; Substance-Related Disorders; Tryptophan | 1984 |
Reversal by naloxone of the effects of chronic administration of drugs of dependence on rat liver and brain tryptophan metabolism.
Topics: Animals; Brain; Corticosterone; Ethanol; Humans; Liver; Naloxone; Nicotine; Phenobarbital; Rats; Serotonin; Substance-Related Disorders; Tryptophan | 1981 |
Exon and intron variants in the human tryptophan 2,3-dioxygenase gene: potential association with Tourette syndrome, substance abuse and other disorders.
Topics: Electrophoresis, Polyacrylamide Gel; Exons; Humans; Introns; Polymorphism, Genetic; Serotonin; Substance-Related Disorders; Tourette Syndrome; Tryptophan; Tryptophan Oxygenase | 1996 |
Studies on tolerance development to single doses of morphine in mice.
Topics: 5,6-Dihydroxytryptamine; Animals; Brain; Cyclic AMP; Cycloheximide; Drug Tolerance; Female; Humans; Hydroxydopamines; Male; Methadone; Mice; Morphine; Pain; Reaction Time; Substance-Related Disorders; Time Factors; Tryptophan | 1976 |
[Schizophrenia and addiction].
Topics: Adult; Amphetamines; Cybernetics; Dopamine; Endorphins; Humans; Lysergic Acid Diethylamide; Male; Norepinephrine; Receptors, Dopamine; Receptors, Serotonin; Schizophrenia; Schizophrenic Psychology; Substance-Related Disorders; Tryptophan | 1978 |
Effects of L-tryptophan on the effects of antitussives.
Topics: Animals; Antitussive Agents; Brain; Codeine; Dextromethorphan; Drug Interactions; Male; Noscapine; Rats; Rats, Inbred Strains; Serotonin; Substance-Related Disorders; Tryptophan | 1990 |
Neuroendocrine and mood responses to intravenous L-tryptophan in 3,4-methylenedioxymethamphetamine (MDMA) users. Preliminary observations.
Topics: 3,4-Methylenedioxyamphetamine; Adult; Affect; Amphetamines; Designer Drugs; Female; Humans; Infusions, Intravenous; Male; Middle Aged; N-Methyl-3,4-methylenedioxyamphetamine; Prolactin; Serotonin; Substance-Related Disorders; Tryptophan | 1989 |
Responses to i.v. L-tryptophan in MDMA users.
Topics: 3,4-Methylenedioxyamphetamine; Adult; Affect; Amphetamines; Designer Drugs; Female; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Prolactin; Receptors, Serotonin; Substance-Related Disorders; Tryptophan | 1989 |
Hypothesis: homozygosity in Tourette syndrome.
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Child; Epistasis, Genetic; Female; Genetic Linkage; Homozygote; Humans; Male; Mental Disorders; Obsessive-Compulsive Disorder; Panic; Pedigree; Serotonin; Substance-Related Disorders; Tic Disorders; Tourette Syndrome; Tryptophan | 1989 |
Cocaine withdrawal. An effective three-drug regimen.
Topics: Amantadine; Cocaine; Humans; Lorazepam; Substance Withdrawal Syndrome; Substance-Related Disorders; Tryptophan | 1989 |
Is L-tryptophan safe?
Topics: Humans; Substance-Related Disorders; Tryptophan | 1988 |
Stepwise detoxification from cocaine. A promising regimen.
Topics: Adolescent; Adult; Amantadine; Bromocriptine; Cocaine; Desipramine; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Middle Aged; Substance Withdrawal Syndrome; Substance-Related Disorders; Tryptophan; Tyrosine | 1988 |
[Treatment of sleep disorders with L-tryptophan. Uses of interval therapy in severe insomnia and hypnotic dependence].
Topics: Drug Administration Schedule; Humans; Hypnotics and Sedatives; Sleep Initiation and Maintenance Disorders; Substance-Related Disorders; Tryptophan | 1987 |
Sleep.
Topics: Amobarbital; Appetite Depressants; Barbiturates; Dreams; Electroencephalography; Fenfluramine; Fluorine; Humans; Methysergide; Narcolepsy; Phenethylamines; Sleep; Sleep Stages; Sleep, REM; Substance-Related Disorders; Time Factors; Tranylcypromine; Tryptophan | 1969 |
Dissociation of morphine tolerance and dependence from brain serotonin synthesis rate in mice.
Topics: Animals; Behavior, Animal; Brain; Brain Chemistry; Drug Tolerance; Humans; Kinetics; Male; Mice; Mixed Function Oxygenases; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Morphine; Pargyline; Serotonin; Substance-Related Disorders; Tryptophan | 1972 |
Screening for aminoacidurias in psychiatric inpatients.
Topics: Affective Symptoms; Amino Acid Metabolism, Inborn Errors; Brain Damage, Chronic; Depression; Drug Synergism; Hartnup Disease; Homocystinuria; Hospitals, Psychiatric; Humans; Intellectual Disability; Mass Screening; Massachusetts; Mental Disorders; Methionine; Monoamine Oxidase Inhibitors; Neurotic Disorders; Personality Disorders; Phenylketonurias; Schizophrenia; Substance-Related Disorders; Tryptophan | 1969 |