tryptophan and Cataract

tryptophan has been researched along with Cataract in 96 studies

Research

Studies (96)

Timeframe	Studies, this research(%)	All Research%
pre-1990	52 (54.17)	18.7374
1990's	14 (14.58)	18.2507
2000's	13 (13.54)	29.6817
2010's	15 (15.63)	24.3611
2020's	2 (2.08)	2.80

Authors

Authors	Studies
Clark, R; Dyba, M; Hejtmancik, JF; Ostrowski, C; Tarasov, SG; Vendra, VPR	1
Butts, CT; Freites, JA; Prytkova, V; Tobias, DJ; Wong, EK	1
Abu-Hussien, M; Gazit, E; Haj, E; Paul, A; Segal, D; Viswanathan, GK	1
Erichsen, JH; Kessel, L; Mensah, A	1
Chen, XJ; Xu, J; Yan, YB; Yao, K; Zhao, WJ	1
Huynh, T; King, JA; Xia, Z; Yang, Z; Zhou, R	2
Srinivasan, K; Suresha, BS	1
King, J; Schafheimer, N; Schey, K; Wang, Z	1
Caceres, MA; Chang, ML; David, LL; Liu, K; Shang, F; Taylor, A; Wawrousek, E; Wilmarth, PA	1
Chaudhury, S; Dasgupta, S; Ghosh, I; Saha, G	1
Davies, MJ; Hawkins, CL; Janmie, JF; Truscott, RJ; Tweeddale, HJ	1
Hemmateenejad, B; Khoshaman, K; Masoudi, R; Yousefi, R; Zm, SZ	1
Buttenschön, KK; Daly, DJ; Dhillon, B; Duncan, RR; Gakamsky, A; Gakamsky, D; Howarth, NM	1
GEIGER, E; SCHAEFFER, AJ	1
Butler, H; Caprara, MH; Doller, C; Howell, S; Mailankot, M; Nagaraj, RH; Reneker, LW; Staniszewska, MM; Wang, B	1
Kanth, VR; Lavanya, K; Raju, TN; Srinivas, J	1
Barton, KA; Bhagyalaxmi, SG; Bhanuprakash Reddy, G; Kumar, KR; Padma, T; Petrash, JM; Srinivas, P; Vidyavathi, M	1
Hu, S; Qi, Y; Zhang, C; Zhao, L; Zhou, G; Zhou, N	1
Babraj, J; Dhillon, B; Gakamsky, DM; Shelton, M; Smith, SD	1
Mamata, M; Nagaraju, T; Padma, T; Reddy, KR; Sridhar, G	1
KAHNEMANN, F	1
DISCHE, Z; ELLIOTT, J; MERRIAM, GR; PEARSON, E	1
KNOX, WE; RIVLIN, RS	1
BARBIROLI, G; CIUSA, W; CRISTINI, G	1
PIKE, RL	1
Fukao, M; Miwa, S; Takikawa, O; Truscott, RJ	1
Fuchs, D; Laganovska, G; Martinsons, A; Pitrans, B; Widner, B	1
MURRAY, JD; SCHAEFFER, AJ	1
Jamie, JF; Streete, IM; Truscott, RJ	1
Backlund, PS; Bityurin, NM; Chelnokov, EV; Hejtmancik, JF; Ostrovsky, MA; Sergeev, YV; Soustov, LV; Wingfield, PT	1
Aquilina, JA; Hains, PG; Korlimbinis, A; Truscott, RJ	1
Korlimbinis, A; Truscott, RJ	1
Kanth, VR; Raju, TN; Reddy, PU	1
Dillon, JP; Gaillard, ER; Garland, DL; Merriam, JC; Paik, DC; Rousseva, LA; Ryzhov, V	1
Cotlier, E; Sharma, YR	2
Allegri, G; Angi, MR	1
Chadwick, C; Phipps, DA; Powell, C	1
Auricchio, G; Libondi, T	1
Dillon, J; Garcia Castineiras, S; Santiago, MA; Spector, A	1
Borkman, RF	1
Auricchio, G; Della Pietra, F; Libondi, T; Menzione, M; Miele, L; Pulcino, D; Rinaldi, E	1
Dillon, J	1
Carreau, JP; Chaudun, E; Counis, MF; Courtois, Y	1
Augusteyn, RC; McNamara, M	1
Bours, J; Dragomirescu, V; Hockwin, O; Koch, HR; Ohrloff, C; Riemann, G	1
Allegri, G; Angi, MR; Costa, C; De Carli, M; Vanzan, S	1
Allegri, G; Angi, MR; Costa, C; Vanzan, S	1
Cotlier, E; Irvine, J; Pucklin, J; Sharma, YR; Teasley, B; Zuckerman, J	1
Cotlier, E	1
Haverkamp, J; Hoenders, HJ; van Haard, PM; Wollensak, J	1
Gafni, A; Schauerte, JA	1
Elderfield, AJ; Truscott, RJ	3
Truscott, RJ; Wood, AM	1
Kamei, A	1
Fukuda, R; Iwase, T; Matsukawa, S; Shirao, E; Shirao, Y	1
Birlouez-Aragon, I; Junes, P; Lecerf, JM; Mondon, H; Moreaux, V; Tessier, F	1
Manabe, S; Takahashi, T; Urban, RC; Yuan, J	1
Birlouez-Aragon, I; Junes, P; Mondon, H; Moreaux, V; Tessier, F	1
Richer, SP; Rose, RC	1
Dillon, J; Paik, DC	1
Atwood, CS; Bowden, EF; Bush, AI; Chylack, LT; Faget, KY; Goldstein, LE; Hartshorn, M; Huang, X; Leopold, MC; Lim, JT; Muffat, JA; Saunders, AJ; Scarpa, RC; Tanzi, RE	1
Finch, ED; Weiter, JJ	1
Zigman, S	2
Borkman, RF; Lerman, S	1
Subramanian, S; Weiter, JJ	1
Bours, J; Hockwin, O; Koch, HR; Ohrloff, C; Stoffel, C; Wefers, U	1
Dillon, J; Garcia-Castineiras, S; Spector, A	2
Bunce, GE; Fillnow, GM; Hess, JL	1
Azari, P; Takemoto, LJ	1
van Heyningen, R	1
Bours, J; Hockwin, O; Koch, HR; Ohrloff, C; Stoffel, C	1
Dilley, KJ	1
Bunce, GE; Hess, JL	1
Elderfield, A; Truscott, R	1
Franke, G; Grimm, U; Knapp, A; Mellenthin, R; Seidlitz, G	1
Bazin, M; Cirne de Castro, J; Conte, J; Lawrence, D; Ribeiro, L; Sa e Melo, T; Santus, R	1
Martin, F; Truscott, RJ	1
Hockwin, O; Schmidt, J; Schmitt, C; Wegener, A	1
Chylack, LT; Liang, JN	1
Bessems, GJ; Hoenders, HJ	1
Augusteyn, RC; Boyd, A; Carroll, N; Maclean, H; Merkrebs, J	1
Bender, DA; McCreanor, GM; Salih, MA	1
Nance, WE; Paulson, GW; Son, CD	1
Borkman, RF; Kurzel, RB; Staton, GW; Wolbarsht, M; Yamanashi, BS	1
Kurzel, RB; Wolbarsht, ML; Yamanashi, BS	1
Bunce, GE; Caasi, P; Chaves, N; Hall, B	1
Binazzi, M; Calandra, P	1
Pirie, A	1
Bertelsen, TI; Ehlers, N	1
Barber, GW	1

Reviews

3 review(s) available for tryptophan and Cataract

Article	Year
The physiologic and pharmacologic factors protecting the lens transparency and the update approach to the prevention of experimental cataracts: a review. Metabolic, pediatric, and systemic ophthalmology, 1983, Volume: 7, Issue:2 Topics: Animals; Cataract; Flavonoids; Humans; Lens, Crystalline; Lysophosphatidylcholines; Osmosis; Oxidation-Reduction; Tryptophan; Ultraviolet Rays; Vitamin E	1983
Ocular hazards and potential uses of near-ultraviolet light. Eye, ear, nose & throat monthly, 1976, Volume: 55, Issue:3 Topics: Animals; Cataract; Crystallins; Eye; Humans; Keratitis, Dendritic; Lens, Crystalline; Neoplasms, Experimental; Radiation Injuries; Radiation Injuries, Experimental; Radiodermatitis; Simplexvirus; Skin Neoplasms; Tryptophan; Ultraviolet Therapy	1976
Ultraviolet radiation as a risk factor in cataractogenesis. Developments in ophthalmology, 1989, Volume: 17 Topics: Cataract; Epidemiologic Methods; Humans; Risk Factors; Tryptophan; Ultraviolet Rays	1989

Other Studies

93 other study(ies) available for tryptophan and Cataract

Article	Year
The Y46D Mutation Destabilizes Dense Packing of the Second Greek Key Pair of Human γC-Crystallin Causing Congenital Nuclear Cataracts. Biochemistry, 2023, 06-20, Volume: 62, Issue:12 Topics: Cataract; Escherichia coli; gamma-Crystallins; Humans; Mutation; Tryptophan	2023
Molecular Mechanism of Aggregation of the Cataract-Related γD-Crystallin W42R Variant from Multiscale Atomistic Simulations. Biochemistry, 2019, 09-03, Volume: 58, Issue:35 Topics: Amino Acid Substitution; Arginine; Cataract; gamma-Crystallins; Humans; Hydrophobic and Hydrophilic Interactions; Lens, Crystalline; Models, Molecular; Molecular Dynamics Simulation; Mutant Proteins; Protein Aggregates; Protein Aggregation, Pathological; Protein Conformation; Protein Denaturation; Protein Folding; Protein Multimerization; Tryptophan	2019
An amyloidogenic hexapeptide from the cataract-associated γD-crystallin is a model for the full-length protein and is inhibited by naphthoquinone-tryptophan hybrids. International journal of biological macromolecules, 2020, Aug-15, Volume: 157 Topics: Amino Acid Sequence; Amyloid; Cataract; Dose-Response Relationship, Drug; gamma-Crystallins; Humans; Models, Molecular; Molecular Conformation; Naphthalenes; Oligopeptides; Protein Aggregates; Protein Aggregation, Pathological; Recombinant Proteins; Structure-Activity Relationship; Tryptophan	2020
Non-invasive tryptophan fluorescence measurements as a novel method of grading cataract. Experimental eye research, 2017, Volume: 165 Topics: Aged; Aged, 80 and over; Cataract; Diagnostic Techniques, Ophthalmological; Female; Fluorescence; Humans; Male; Middle Aged; Phacoemulsification; Photography; Tryptophan	2017
Introduction of an extra tryptophan fluorophore by cataract-associating mutations destabilizes βB2-crystallin and promotes aggregation. Biochemical and biophysical research communications, 2018, 10-12, Volume: 504, Issue:4 Topics: beta-Crystallin B Chain; Cataract; Evolution, Molecular; Fluorescence; Humans; Molecular Dynamics Simulation; Protein Denaturation; Protein Stability; Spectrophotometry, Ultraviolet; Tryptophan; Ultraviolet Rays	2018
UV-radiation induced disruption of dry-cavities in human γD-crystallin results in decreased stability and faster unfolding. Scientific reports, 2013, Volume: 3 Topics: Cataract; gamma-Crystallins; Humans; Hydrophobic and Hydrophilic Interactions; Kynurenine; Molecular Dynamics Simulation; Protein Stability; Protein Unfolding; Tryptophan; Tyrosine; Ultraviolet Rays	2013
Antioxidant potential of fungal metabolite nigerloxin during eye lens abnormalities in galactose-fed rats. Current eye research, 2013, Volume: 38, Issue:10 Topics: Aldehyde Reductase; Animals; Antioxidants; Aspergillus niger; Benzoates; Cataract; Diabetes Mellitus, Experimental; Galactose; Glutathione; Lens, Crystalline; Lipid Peroxidation; Male; Oxidative Stress; Polymers; Propane; Rats; Rats, Wistar; Sulfhydryl Compounds; Tryptophan	2013
Dissecting the contributions of β-hairpin tyrosine pairs to the folding and stability of long-lived human γD-crystallins. Nanoscale, 2014, Volume: 6, Issue:3 Topics: Alanine; Cataract; Cations; gamma-Crystallins; Humans; Hydrophobic and Hydrophilic Interactions; Kynurenine; Models, Molecular; Molecular Dynamics Simulation; Mutation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Tryptophan; Tyrosine; Ultraviolet Rays	2014
Tyrosine/cysteine cluster sensitizing human γD-crystallin to ultraviolet radiation-induced photoaggregation in vitro. Biochemistry, 2014, Feb-18, Volume: 53, Issue:6 Topics: Amino Acid Substitution; Cataract; Cysteine; gamma-Crystallins; Humans; Lens, Crystalline; Protein Denaturation; Protein Folding; Protein Structure, Quaternary; Tryptophan; Tyrosine; Ultraviolet Rays	2014
Newborn mouse lens proteome and its alteration by lysine 6 mutant ubiquitin. Journal of proteome research, 2014, Mar-07, Volume: 13, Issue:3 Topics: Amino Acid Substitution; Animals; Animals, Newborn; Cataract; Eye Proteins; Gene Expression Profiling; Gene Expression Regulation, Developmental; Lens, Crystalline; Lysine; Mice; Mice, Transgenic; Mutagenesis, Site-Directed; Proteasome Endopeptidase Complex; Proteome; Tryptophan; Ubiquitin	2014
EGCG prevents tryptophan oxidation of cataractous ocular lens human γ-crystallin in presence of H2O2. International journal of biological macromolecules, 2015, Volume: 77 Topics: Cataract; Catechin; gamma-Crystallins; Humans; Hydrogen Peroxide; Lens, Crystalline; Middle Aged; Molecular Docking Simulation; Oxidation-Reduction; Protein Conformation; Tryptophan	2015
Cross-linking of lens crystallin proteins induced by tryptophan metabolites and metal ions: implications for cataract development. Free radical research, 2016, Volume: 50, Issue:10 Topics: Cataract; Crystallins; Humans; Lens, Crystalline; Tryptophan	2016
The structural alteration and aggregation propensity of glycated lens crystallins in the presence of calcium: Importance of lens calcium homeostasis in development of diabetic cataracts. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2017, Jan-05, Volume: 170 Topics: Animals; Benzothiazoles; Calcium; Cataract; Cattle; Chymotrypsin; Circular Dichroism; Cross-Linking Reagents; Crystallins; Diabetes Mellitus; Dynamic Light Scattering; Fluorescence; Glycosylation; Homeostasis; Ions; Kinetics; Lens, Crystalline; Molecular Weight; Protein Aggregates; Protein Conformation; Protein Stability; Proteolysis; Thiazoles; Tryptophan	2017
Tryptophan and Non-Tryptophan Fluorescence of the Eye Lens Proteins Provides Diagnostics of Cataract at the Molecular Level. Scientific reports, 2017, 01-10, Volume: 7 Topics: Animals; Cataract; Chromatography, High Pressure Liquid; Crystallins; Fluorescence; Humans; Lens, Crystalline; Mass Spectrometry; Protein Processing, Post-Translational; Spectrometry, Fluorescence; Swine; Tryptophan; Ultraviolet Rays	2017
Cataract development in animals with delayed supplementation of tryptophane. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1947, Volume: 66, Issue:2 Topics: Cataract; Dietary Supplements; Tryptophan	1947
Indoleamine 2,3-dioxygenase overexpression causes kynurenine-modification of proteins, fiber cell apoptosis and cataract formation in the mouse lens. Laboratory investigation; a journal of technical methods and pathology, 2009, Volume: 89, Issue:5 Topics: Animals; Apoptosis; Cataract; Glutathione; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Lens, Crystalline; Mice; Mice, Transgenic; Tryptophan	2009
Elevated Expression of indoleamine 2,3-dioxygenase (IDO) and accumulation of kynurenic acid in the pathogenesis of STZ-induced diabetic cataract in Wistar rats. Current eye research, 2009, Volume: 34, Issue:4 Topics: Animals; Cataract; Diabetes Mellitus, Experimental; Down-Regulation; Glutathione; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynurenic Acid; Lens, Crystalline; Male; Oxidative Stress; Oxidoreductases; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Tryptophan	2009
A novel mutation (F71L) in alphaA-crystallin with defective chaperone-like function associated with age-related cataract. Biochimica et biophysica acta, 2009, Volume: 1792, Issue:10 Topics: Aging; alpha-Crystallin A Chain; Amino Acid Substitution; Base Sequence; Case-Control Studies; Cataract; Chromatography, Gel; Circular Dichroism; DNA Mutational Analysis; Electrophoresis, Polyacrylamide Gel; Exons; Female; Genetic Predisposition to Disease; Humans; Light; Male; Middle Aged; Molecular Sequence Data; Mutant Proteins; Mutation; Protein Structure, Quaternary; Scattering, Radiation; Spectrometry, Fluorescence; Time Factors; Tryptophan	2009
A missense mutation in CRYBA4 associated with congenital cataract and microcornea. Molecular vision, 2010, Jun-05, Volume: 16 Topics: Adolescent; Adult; Amino Acid Substitution; Base Sequence; beta-Crystallin A Chain; Cataract; Child; Child, Preschool; Cornea; Eye Abnormalities; Female; Glycine; Guanine; Humans; Male; Models, Chemical; Molecular Biology; Mutation, Missense; Pedigree; Thymine; Tryptophan; Young Adult	2010
Exploring the possibility of early cataract diagnostics based on tryptophan fluorescence. Journal of the Royal Society, Interface, 2011, Nov-07, Volume: 8, Issue:64 Topics: Animals; Cataract; Dose-Response Relationship, Radiation; Fluorescence; Humans; Sus scrofa; Tryptophan; Ultraviolet Rays	2011
Is the variant c.422+90G → A in intron 4 of indoleamine 2, 3 -dioxygenase (IDO) gene related to age related cataracts? Molecular vision, 2011, Volume: 17 Topics: Age of Onset; Aged; Aged, 80 and over; Aging; Body Mass Index; Case-Control Studies; Cataract; Exons; Eye; Eye Proteins; Female; Humans; India; Indoleamine-Pyrrole 2,3,-Dioxygenase; Introns; Lens, Crystalline; Male; Middle Aged; Polymorphism, Restriction Fragment Length; Restriction Mapping; Risk Factors; Sex Factors; Smoking; Tryptophan	2011
[Tryptophan content of human crystalline lens in normal conditions and in cataract demonstrated by the Adams method; histochemical study]. Annali di ottalmologia e clinica oculistica, 1957, Volume: 83, Issue:11 Topics: Cataract; Humans; Lens, Crystalline; Tryptophan	1957
Changes in proteins and protein synthesis; in tryptophane deficiency and radiation cataracts of rats. American journal of ophthalmology, 1959, Volume: 47, Issue:1 Pt 2 Topics: Animals; Cataract; Proteins; Rats; Tryptophan; X-Rays	1959
Effects of age, body size and growth hormone on level of tryptophan peroxidase-oxidase in rat liver. The American journal of physiology, 1959, Volume: 197, Issue:1 Topics: Aging; Animals; Body Size; Body Weight; Cataract; Growth Hormone; Human Growth Hormone; Liver; Oxidoreductases; Peroxidase; Peroxidases; Rats; Tryptophan	1959
THE TRANSMETHYLATION PROCESSES IN THE AQUEOUS HUMOUR AND IN THE LENS. Experimental eye research, 1964, Volume: 3 Topics: Aqueous Humor; Cataract; Lens, Crystalline; Metabolism; Niacin; Nicotinic Acids; Research; Tryptophan	1964
Congenital cataract in albino rats fed different amounts of tryphophan and niacin. The Journal of nutrition, 1951, Volume: 44, Issue:2 Topics: Animals; Cataract; Niacin; Nicotinic Acids; Rats; Tryptophan	1951
Age-related nuclear cataract and indoleamine 2,3-dioxygenase-initiated tryptophan metabolism in the human lens. Advances in experimental medicine and biology, 2003, Volume: 527 Topics: Adult; Aged; Aged, 80 and over; Aging; Blotting, Western; Cataract; Chromatography, High Pressure Liquid; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Lens, Crystalline; Middle Aged; Tryptophan; Tryptophan Oxygenase; Ultraviolet Rays	2003
Kynurenine and neopterin in the aqueous humor of the anterior chamber of the eye and in serum of cataract patients. Advances in experimental medicine and biology, 2003, Volume: 527 Topics: Aged; Aged, 80 and over; Aqueous Humor; Cataract; Exfoliation Syndrome; Humans; Kynurenine; Neopterin; Oxidative Stress; Selenium; Tryptophan	2003
Tryptophan determination in cataract due to deficiency or delayed supplementation of tryptophan. Archives of ophthalmology (Chicago, Ill. : 1929), 1950, Volume: 43, Issue:2 Topics: Cataract; Dietary Supplements; Humans; Tryptophan	1950
Lenticular levels of amino acids and free UV filters differ significantly between normals and cataract patients. Investigative ophthalmology & visual science, 2004, Volume: 45, Issue:11 Topics: Adult; Aged; Aged, 80 and over; Cataract; Chromatography, High Pressure Liquid; Glucosides; Humans; Kynurenine; Lens, Crystalline; Middle Aged; Phenylbutyrates; Tryptophan; Tyrosine; Ultraviolet Rays; Uric Acid	2004
Increased sensitivity of amino-arm truncated betaA3-crystallin to UV-light-induced photoaggregation. Investigative ophthalmology & visual science, 2005, Volume: 46, Issue:9 Topics: Aging; Animals; Baculoviridae; beta-Crystallin A Chain; Blotting, Western; Cataract; Chromatography, Gel; Crystallins; Electrophoresis, Polyacrylamide Gel; Gene Expression; Light; Methionine; Mice; Oxidation-Reduction; Photochemistry; Photolysis; Protein Denaturation; Recombinant Proteins; Scattering, Radiation; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tryptophan; Ultraviolet Rays	2005
3-Hydroxykynurenine oxidizes alpha-crystallin: potential role in cataractogenesis. Biochemistry, 2006, Feb-14, Volume: 45, Issue:6 Topics: alpha-Crystallins; Animals; Catalysis; Cataract; Cattle; Chromatography, High Pressure Liquid; Cysteine; Humans; Kynurenine; Lens, Crystalline; Mass Spectrometry; Methionine; Oxidation-Reduction; Oxidative Stress; Sunscreening Agents; Tryptophan; Ultraviolet Rays	2006
Identification of 3-hydroxykynurenine bound to proteins in the human lens. A possible role in age-related nuclear cataract. Biochemistry, 2006, Feb-14, Volume: 45, Issue:6 Topics: Aging; Animals; Butterflies; Cataract; Humans; Kynurenine; Lens, Crystalline; Moths; Oxidation-Reduction; Peptides; Pigmentation; Protein Binding; Proteins; Solubility; Sunscreening Agents; Time Factors; Tryptophan; Ultraviolet Rays	2006
Influence of kynurenines in pathogenesis of cataract formation in tryptophan-deficient regimen in Wistar rats. Indian journal of experimental biology, 2007, Volume: 45, Issue:6 Topics: Animals; Antioxidants; Cataract; Diet; Kynurenine; Lens, Crystalline; Microscopy, Fluorescence; Oxidative Stress; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Tryptophan	2007
Oxindolealanine in age-related human cataracts. Experimental eye research, 2007, Volume: 85, Issue:6 Topics: Aged; Aged, 80 and over; Alanine; alpha-Crystallins; Animals; Biomarkers; Cataract; Cattle; Chromatography, High Pressure Liquid; Humans; Indoles; Lens Cortex, Crystalline; Lens Nucleus, Crystalline; Lens, Crystalline; Oxidation-Reduction; Oxindoles; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Tryptophan	2007
Plasma tryptophan in senile cataract. Lancet (London, England), 1980, Mar-15, Volume: 1, Issue:8168 Pt 1 Topics: Aged; Aspirin; Cataract; Humans; Tryptophan	1980
Free and total serum tryptophan in senile cataract. Lancet (London, England), 1981, Jul-18, Volume: 2, Issue:8238 Topics: Aged; Cataract; Humans; Tryptophan	1981
Senile cataract and plasma tryptophan. Lancet (London, England), 1981, Sep-05, Volume: 2, Issue:8245 Topics: Aged; Cataract; Humans; Tryptophan	1981
Serum tryptophan and cataract. Lancet (London, England), 1981, Sep-12, Volume: 2, Issue:8246 Topics: Aged; Cataract; Female; Humans; Male; Middle Aged; Tryptophan	1981
The endopeptidase-resistant protein fraction from human cataractous lenses. Experimental eye research, 1984, Volume: 39, Issue:1 Topics: Amino Acids; Cataract; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, High Pressure Liquid; Crystallins; Endopeptidases; Humans; In Vitro Techniques; Kynurenine; Oxindoles; Spectrophotometry; Tryptophan	1984
Cataracts and photochemical damage in the lens. Ciba Foundation symposium, 1984, Volume: 106 Topics: Animals; Cataract; Crystallins; Dose-Response Relationship, Radiation; In Vitro Techniques; Lasers; Lens, Crystalline; Radiation Injuries, Experimental; Rats; Rats, Inbred Strains; Tryptophan; Ultraviolet Rays	1984
Serum tryptophan in humans with senile cataracts. Metabolic, pediatric, and systemic ophthalmology, 1983, Volume: 7, Issue:2 Topics: Aged; Cataract; Female; Humans; Male; Protein Binding; Tryptophan	1983
Photolytic changes in lens proteins. Current eye research, 1984, Volume: 3, Issue:1 Topics: Adolescent; Aged; Aging; Animals; Cataract; Cattle; Crystallins; Glucosides; Humans; In Vitro Techniques; Kynurenine; Lens, Crystalline; Photochemistry; Photolysis; Tryptophan	1984
Changes in the DNA breakage and crystallin synthesis of embryonic chicken lenses cultured in a tryptophan-deficient medium. Experimental eye research, 1984, Volume: 38, Issue:1 Topics: Animals; Cataract; Cells, Cultured; Centrifugation, Density Gradient; Chick Embryo; Crystallins; DNA; Electrophoresis, Polyacrylamide Gel; Lens, Crystalline; Molecular Weight; Tryptophan	1984
The effects of hydrogen peroxide on lens proteins: a possible model for nuclear cataract. Experimental eye research, 1984, Volume: 38, Issue:1 Topics: Amino Acids; Cataract; Crystallins; Humans; Hydrogen Peroxide; In Vitro Techniques; Lens Nucleus, Crystalline; Lens, Crystalline; Methionine; Models, Biological; Peptide Fragments; Protein Conformation; Solubility; Spectrometry, Fluorescence; Spectrophotometry; Sulfhydryl Compounds; Tryptophan	1984
Separation of lens proteins in rats with tryptophan deficiency cataracts. Experimental eye research, 1982, Volume: 34, Issue:4 Topics: Animals; Body Water; Body Weight; Cataract; Crystallins; Isoelectric Focusing; Lens, Crystalline; Organ Size; Rats; Rats, Inbred Strains; Tryptophan	1982
Metabolism and serum levels of tryptophan in senile cataract patients. Bollettino della Societa italiana di biologia sperimentale, 1982, Mar-30, Volume: 58, Issue:6 Topics: Age Factors; Aged; Cataract; Female; Humans; Kynurenine; Male; Middle Aged; Sex Factors; Tryptophan	1982
Tryptophan lens levels in senile cataract. Bollettino della Societa italiana di biologia sperimentale, 1982, Mar-30, Volume: 58, Issue:6 Topics: Aged; Cataract; Female; Humans; Kynurenine; Lens, Crystalline; Male; Middle Aged; Oxidation-Reduction; Photochemistry; Tryptophan	1982
Plasma tryptophan in humans with diabetic and senile cataracts. Experimental eye research, 1981, Volume: 33, Issue:3 Topics: Adult; Aged; Aphakia, Postcataract; Cataract; Diabetes Complications; Diabetes Mellitus; Humans; Middle Aged; Tryptophan	1981
Senile cataracts: evidence for acceleration by diabetes and deceleration by salicylate. Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1981, Volume: 16, Issue:3 Topics: Age Factors; Aged; Aspirin; Cataract; Diabetes Complications; Humans; Middle Aged; Osteoarthritis; Time Factors; Tryptophan	1981
Pyrolysis mass spectra, sulfhydryl and tryptophan content of the embryonic nuclei from adult human normal and nuclear-cataractous lenses. Biochimica et biophysica acta, 1980, Aug-01, Volume: 631, Issue:1 Topics: Cataract; Computers; Humans; Lens, Crystalline; Mass Spectrometry; Pyrroles; Sulfhydryl Compounds; Tryptophan	1980
Photodegradation of tryptophan residues and attenuation of molecular chaperone activity in alpha-crystallin are correlated. Biochemical and biophysical research communications, 1995, Jul-26, Volume: 212, Issue:3 Topics: Aging; Animals; Cataract; Crystallins; Hot Temperature; Humans; In Vitro Techniques; Molecular Chaperones; Photochemistry; Protein Conformation; Rabbits; Spectrometry, Fluorescence; Tryptophan; Ultraviolet Rays	1995
Serum tryptophan and age-related cataract. Developments in ophthalmology, 1994, Volume: 26 Topics: Age Factors; Aged; Cataract; Chromatography, High Pressure Liquid; Female; Humans; Male; Middle Aged; Tryptophan	1994
Tryptophan metabolism and the reactive metabolite hypothesis for human cataract. Developments in ophthalmology, 1994, Volume: 26 Topics: Cataract; Humans; Lens, Crystalline; Tryptophan	1994
Glutathione levels of the human crystalline lens in aging and its antioxidant effect against the oxidation of lens proteins. Biological & pharmaceutical bulletin, 1993, Volume: 16, Issue:9 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Antioxidants; Cataract; Child; Chromatography, High Pressure Liquid; Circular Dichroism; Crystallins; Glutathione; Glutathione Reductase; Humans; Lens, Crystalline; Middle Aged; Oxidation-Reduction; Protein Binding; Thiobarbituric Acid Reactive Substances; Tryptophan; Tyrosine	1993
Relationship between serum tryptophan and tryptophan metabolite levels after tryptophan ingestion in normal subjects and age-related cataract patients. Clinical science (London, England : 1979), 1995, Volume: 89, Issue:6 Topics: Age Factors; Aged; Aged, 80 and over; Case-Control Studies; Cataract; Fasting; Female; Humans; Kynurenine; Male; Middle Aged; ortho-Aminobenzoates; Tryptophan; Xanthurenates	1995
[Comparison of free non-tryptophan fluorescent substances in water-soluble fraction of brunescent and non-brunescent human cataract]. Nippon Ganka Gakkai zasshi, 1996, Volume: 100, Issue:5 Topics: Cataract; Chromatography, High Pressure Liquid; Fluorescence; Glucosides; Humans; Kynurenine; Lens, Crystalline; Solubility; Tryptophan	1996
Is an altered tryptophan metabolism responsible for age-related cataract? Advances in experimental medicine and biology, 1996, Volume: 398 Topics: 3-Hydroxyanthranilic Acid; Aged; Cataract; Chromatography, High Pressure Liquid; Female; Humans; Kynurenine; Male; Reference Values; Sensitivity and Specificity; Tryptophan	1996
Trp oxidation by copper-ascorbate under physiological conditions. Advances in experimental medicine and biology, 1996, Volume: 398 Topics: Adult; Aged; Aged, 80 and over; Ascorbic Acid; Cardiovascular Diseases; Cataract; Copper; Diabetes Mellitus; Diet; Humans; Lens, Crystalline; Middle Aged; Oxidation-Reduction; Peptides; Reference Values; Regression Analysis; Tryptophan	1996
Age-related accumulation of 1-methyl-1,2,3,4-tetrahydro-beta-carboline-3- carboxylic acid in human lens. Experimental eye research, 1996, Volume: 63, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Carbolines; Cataract; Chromatography, High Pressure Liquid; Glucose; Hot Temperature; Humans; In Vitro Techniques; Lens, Crystalline; Middle Aged; Tryptophan	1996
Decrease in vitamin C concentration in human lenses during cataract progression. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1998, Volume: 68, Issue:5 Topics: Ascorbic Acid; Cataract; Disease Progression; Female; Fructose; Humans; Lens Nucleus, Crystalline; Lysine; Male; Sensitivity and Specificity; Tryptophan	1998
Water soluble antioxidants in mammalian aqueous humor: interaction with UV B and hydrogen peroxide. Vision research, 1998, Volume: 38, Issue:19 Topics: Aged; Analysis of Variance; Animals; Antioxidants; Aqueous Humor; Ascorbic Acid; Cataract; Chromatography, High Pressure Liquid; Cysteine; Disease Models, Animal; Female; Glutathione; Humans; Hydrogen Peroxide; Mammals; Oxidants; Rabbits; Rats; Rats, Sprague-Dawley; Tryptophan; Tyrosine; Ultraviolet Rays; Uric Acid	1998
The Nitrite/alpha crystallin reaction: a possible mechanism in lens matrix damage. Experimental eye research, 2000, Volume: 70, Issue:1 Topics: Aging; Animals; Cataract; Cattle; Chromatography, High Pressure Liquid; Crystallins; Electrophoresis, Polyacrylamide Gel; Humans; Kynurenine; Lens, Crystalline; Nitrites; Oxidation-Reduction; Smoking; Spectrophotometry, Ultraviolet; Tryptophan; Ultraviolet Rays	2000
3-Hydroxykynurenine and 3-hydroxyanthranilic acid generate hydrogen peroxide and promote alpha-crystallin cross-linking by metal ion reduction. Biochemistry, 2000, Jun-20, Volume: 39, Issue:24 Topics: 3-Hydroxyanthranilic Acid; Animals; Ascorbic Acid; Cataract; Cattle; Copper; Crystallins; Electrochemistry; Humans; Hydrogen Peroxide; Iron; Kynurenine; Lens, Crystalline; Metals; Oxidation-Reduction; Superoxides; Tryptophan	2000
Paramagnetic species in cataractous human lenses. Nature, 1975, Apr-10, Volume: 254, Issue:5500 Topics: Cataract; Crystallins; Electron Spin Resonance Spectroscopy; Humans; Lens, Crystalline; Tryptophan	1975
Evidence for a free radical mechanism in aging and u.v.-irradiated ocular lenses. Experimental eye research, 1977, Volume: 25, Issue:3 Topics: Aging; Animals; Cataract; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Lens, Crystalline; Penicillamine; Rats; Tryptophan; Ultraviolet Rays	1977
Free radicals produced in human lenses by a biphotonic process. Investigative ophthalmology & visual science, 1978, Volume: 17, Issue:9 Topics: Aged; Cataract; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Lens, Crystalline; Middle Aged; Spectrophotometry, Ultraviolet; Tryptophan; Ultraviolet Rays	1978
Experimental cataracts in rats due to tryptophan-free diet. Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1978, Jan-31, Volume: 205, Issue:2 Topics: Animals; Body Weight; Cataract; Deficiency Diseases; Female; Isoelectric Focusing; Lens, Crystalline; Organ Size; Rats; Tryptophan	1978
Effects of reduction on absorption and fluorescence of human lens protein. Experimental eye research, 1979, Volume: 29, Issue:5 Topics: Aging; Cataract; Crystallins; Humans; Oxidation-Reduction; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tryptophan	1979
Investigation of low tryptophan induced cataract in weanling rats. Experimental eye research, 1978, Volume: 26, Issue:4 Topics: Animals; Cataract; Crystallins; Lens, Crystalline; Male; Rats; Tryptophan; Weaning	1978
Non-tryptophan fluorescence associated with human lens protein; apparent complexity and isolation of bityrosine and anthranilic acid. Experimental eye research, 1978, Volume: 26, Issue:4 Topics: Cataract; Crystallins; Humans; Lens, Crystalline; ortho-Aminobenzoates; Spectrometry, Fluorescence; Tryptophan; Tyrosine	1978
Amino acid composition of normal and cataractous human lens proteins. Experimental eye research, 1976, Volume: 23, Issue:1 Topics: Aged; Amino Acids; Cataract; Crystallins; Cysteine; Cystine; Glutathione; Humans; Middle Aged; Tryptophan	1976
Experimental studies on cataract. Investigative ophthalmology & visual science, 1976, Volume: 15, Issue:9 Topics: Aging; Animals; Ascorbic Acid; Cataract; Crystallins; Diabetic Retinopathy; Humans; Lens, Crystalline; Naphthalenes; Naphthoquinones; Peptide Hydrolases; Sorbitol; Tryptophan	1976
Proceedings: Experimental cataracts induced by a tryptophan-free diet. Experimental eye research, 1975, Volume: 20, Issue:2 Topics: Animals; Cataract; Crystallins; Diet; Lens, Crystalline; Rats; Tryptophan	1975
Letter: Ultraviolet light and human cataract. Nature, 1975, Sep-04, Volume: 257, Issue:5521 Topics: Cataract; Free Radicals; Humans; Radiation Effects; Tryptophan; Ultraviolet Rays	1975
Lenticular opacities in young rats as a consequence of maternal diets low in tryptopham and/or vitamin E. The Journal of nutrition, 1976, Volume: 106, Issue:2 Topics: Animals; Cataract; Female; Lactation; Lens, Crystalline; Maternal-Fetal Exchange; Pregnancy; Pregnancy Complications; Rats; Tryptophan; Vitamin E Deficiency	1976
Tryptophan metabolism in senile cataract patients assessed by high-performance liquid chromatography. Advances in experimental medicine and biology, 1991, Volume: 294 Topics: Aging; Cataract; Chromatography, High Pressure Liquid; Humans; Kynurenic Acid; Kynurenine; Tryptophan	1991
Tryptophan metabolic studies in patients with presenile cataracts. Biomedica biochimica acta, 1990, Volume: 49, Issue:7 Topics: Adolescent; Adult; Cataract; Female; Humans; Kynurenine; Male; Pyridoxine; Tryptophan; Xanthurenates	1990
Degradation of crystallins from a psoriatic patient undergoing PUVA therapy. FEBS letters, 1990, Jul-30, Volume: 268, Issue:1 Topics: Aging; Cataract; Crystallins; Eye Proteins; Humans; Lens, Crystalline; Molecular Weight; Psoriasis; PUVA Therapy; Solubility; Spectrometry, Fluorescence; Tryptophan	1990
The reaction of proteins with 3-hydroxyanthranilic acid as a possible model for senile nuclear cataract in man. Experimental eye research, 1989, Volume: 49, Issue:6 Topics: 3-Hydroxyanthranilic Acid; Animals; Cataract; Cattle; Chromatography, Gel; Color; Crystallins; Humans; Hydrogen Peroxide; Lysine; Methionine; Models, Biological; Molecular Weight; ortho-Aminobenzoates; Oxidation-Reduction; Serum Albumin, Bovine; Sulfhydryl Compounds; Time Factors; Tryptophan	1989
Spectroscopic study on the effects of nonenzymatic glycation in human alpha-crystallin. Investigative ophthalmology & visual science, 1987, Volume: 28, Issue:5 Topics: Aged; Aged, 80 and over; Anilino Naphthalenesulfonates; Cataract; Circular Dichroism; Crystallins; Diabetes Complications; Diabetes Mellitus; Fluorometry; Glucose; Glycosylation; Humans; Lens Cortex, Crystalline; Lens, Crystalline; Naphthalenesulfonates; Protein Conformation; Protein Processing, Post-Translational; Spectrophotometry; Tryptophan	1987
Distribution of aromatic and fluorescent compounds within single human lenses. Experimental eye research, 1987, Volume: 44, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Aging; Cataract; Chromatography, High Pressure Liquid; Fluorescence; Humans; Lens, Crystalline; Middle Aged; Tryptophan; Tyrosine; Uric Acid	1987
Serum tryptophan and cataract. Australian and New Zealand journal of ophthalmology, 1987, Volume: 15, Issue:3 Topics: Adult; Aged; Cataract; Humans; Osmolar Concentration; Reference Values; Tryptophan	1987
Lethal familial pellagra-like skin lesion associated with neurologic and developmental impairment and the development of cataracts. Pediatrics, 1985, Volume: 76, Issue:5 Topics: Amino Acid Metabolism, Inborn Errors; Cataract; Cerebellar Ataxia; Child, Preschool; Consanguinity; Diagnosis, Differential; Female; Humans; Infant; Intellectual Disability; Male; Pedigree; Pellagra; Skin; Syndrome; Tryptophan	1985
Neurologic aspects of typical and atypical Down's syndrome. Diseases of the nervous system, 1969, Volume: 30, Issue:9 Topics: Cataract; Chromosome Aberrations; Down Syndrome; Gait; Humans; Hydroxyindoleacetic Acid; Intelligence; Mosaicism; Neurologic Manifestations; Seizures; Speech Disorders; Strabismus; Trisomy; Tryptophan; Uric Acid	1969
Tryptophan excited states and cataracts in the human lens. Nature, 1973, Jan-12, Volume: 241, Issue:5385 Topics: Cataract; Crystallins; Humans; Lens, Crystalline; Spectrometry, Fluorescence; Tryptophan	1973
Spectral studies on normal and cataractous intact human lenses. Experimental eye research, 1973, Oct-10, Volume: 17, Issue:1 Topics: Cataract; Crystallins; Humans; Kynurenine; Lens, Crystalline; Pigmentation; Spectrum Analysis; Tryptophan	1973
Prevention of cataract in the progeny of rats fed a maternal diet based on vegetable proteins. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 140, Issue:3 Topics: Abnormalities, Drug-Induced; Animals; Cataract; Dietary Proteins; Female; Maternal-Fetal Exchange; Methionine; Nicotinic Acids; Plant Proteins; Pregnancy; Rats; Tryptophan; Vitamin E	1972
Identification of an error in the tryptophan--niacin pathway in carriers of some dermatoses conditioned or aggravated by sunlight. Archiv fur klinische und experimentelle Dermatologie, 1971, Volume: 239, Issue:4 Topics: Adult; Aged; Animals; Atrophy; Cataract; Female; Gastric Juice; Humans; Hydrolases; Kynurenine; Light; Lupus Erythematosus, Discoid; Male; Middle Aged; Nicotinic Acids; Pellagra; Pigmentation Disorders; Porphyrias; Rats; Rothmund-Thomson Syndrome; Skin; Skin Diseases; Sunlight; Transaminases; Tryptophan; Urticaria	1971
Formation of N'-formylkynurenine in proteins from lens and other sources by exposure to sunlight. The Biochemical journal, 1971, Volume: 125, Issue:1 Topics: Animals; Cataract; Cattle; Chromatography; Crystallins; Electrophoresis; Fluorescence; Humans; In Vitro Techniques; Kynurenine; Muramidase; Oxidation-Reduction; Serum Albumin; Spectrophotometry; Sunlight; Tryptophan	1971
Morphological and histochemical studies on fibrillopathia epitheliocapsularis. Acta ophthalmologica, 1969, Volume: 47, Issue:3 Topics: Aged; Amylases; Arginine; Cataract; Cysteine; Cystine; Endopeptidases; Epithelium; Eye Diseases; Histocytochemistry; Humans; Hyaluronoglucosaminidase; In Vitro Techniques; Lens, Crystalline; Microscopy, Electron; Middle Aged; Ribonucleases; Time Factors; Tryptophan; Tyrosine	1969
Eye lens color: formation and function. Science (New York, N.Y.), 1971, Feb-26, Volume: 171, Issue:3973 Topics: Aging; Aminobenzoates; Animals; Cataract; Crystallins; Eye Proteins; Fluorescence; Lens, Crystalline; Photochemistry; Pigments, Biological; Radiation Effects; Sharks; Spectrophotometry; Tryptophan; Ultraviolet Rays	1971
Free amino acids in senile cataractous lenses: possible osmotic etiology. Investigative ophthalmology, 1968, Volume: 7, Issue:5 Topics: Adult; Age Factors; Aged; Amino Acids; Animals; Aqueous Humor; Biological Transport, Active; Cataract; Chromatography; Crystallins; Diabetes Mellitus, Experimental; Female; Guinea Pigs; Humans; Lens, Crystalline; Male; Middle Aged; Osmosis; Protein Biosynthesis; Protein Deficiency; Rabbits; Tissue Banks; Tryptophan; Vision, Ocular; Water; Water-Electrolyte Balance; Weights and Measures	1968