tryptophan has been researched along with Breast Neoplasms in 88 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 25 (28.41) | 18.7374 |
1990's | 3 (3.41) | 18.2507 |
2000's | 10 (11.36) | 29.6817 |
2010's | 29 (32.95) | 24.3611 |
2020's | 21 (23.86) | 2.80 |
Authors | Studies |
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Fan, D; Fang, J; Feng, C; He, L; Liang, W; Qin, X; Wang, Q | 1 |
Almeida, MAP; Batista, AA; Burikhanov, R; Castro, CH; de Sousa, MAM; Delmond, KA; Gomes, CC; Guedes, APM; Matuda, L; Mello-Andrade, F; Melo-Reis, P; Menck, CFM; Mendes, D; Molina, MS; Pires, WC; Rangnekar, VM; Silveira-Lacerda, E; Velozo-Sá, VS | 1 |
Piyu, J; Song, J; Yi, X; Zang, X | 1 |
Baumann, L; Gahlawat, AW; Hauke, J; Nees, J; Okun, JG; Schuhn, A; Tobar, TW | 1 |
Ardestani, MS; Balouchi, EN; Salehi, Z; Seyyedi Zadeh, E; Tokmedash, MA | 1 |
Danciu, OC; Doorenbos, AZ; Li, H; Liu, T; Lockwood, MB; Schlaeger, JM | 1 |
Azimnasab-Sorkhabi, P; Kfoury Junior, JR; Massoco, CO; Soltani-Asl, M; Yoshinaga, TT | 1 |
Ahn, SB; Girithar, HN; Gluch, L; Guillemin, GJ; Heng, B; Staats Pires, A | 1 |
Dhandapani, H; Karadkar, S; Siddiqui, A; Tayalia, P | 1 |
Abdel-Aal, FAM; Abdeltawab, AA; Kamel, RM; Mohamed, AI; Mohamed, FA | 1 |
Bein, K; Castaneda, AR; Garrity, N; Haarmann-Stemmann, T; Ishihara, Y; Kado, SY; Pouraryan, AA; Rossi, A; Sweeney, CA; Vogel, CFA | 1 |
Deng, G; Hussain, A; Kang, X; Xie, L | 1 |
Aprile, S; Del Grosso, E; Di Martino, RMC; Fallarini, S; Rezzi, SJ; Villani, S | 1 |
Liu, L; Luo, D; Qian, Y; Wang, C; Xue, L; Yang, X; Zhang, S; Zhu, W | 1 |
Rachwał, K; Sadok, I; Staniszewska, M | 1 |
Amaro, F; Duarte, D; Fresco, P; Gonçalves, J; Oliveira, JC; Reguengo, H; Silva, D; Silva, I; Vale, N | 1 |
Bhattacharyya, A; Chatterjee, S; Kumar, S; Manna, D; Morla, S; Panda, S; Pradhan, N; Roy, A; Saha, A | 1 |
Chen, C; Du, W; Fan, C; Jiang, X; Liu, Y; Sun, P; Wu, J; Yan, C; Zhang, J; Zhang, R; Zhang, S; Zhang, X | 1 |
Dashti, S; Ghafouri-Fard, S; Kholghi Oskooei, V; Samsami, M; Taheri, M; Taherian-Esfahani, Z | 1 |
Danciu, O; Dillon, P; Gilman, P; Han, H; Ibrahim, NK; Ismail-Khan, R; Kennedy, E; Link, C; Mariotti, V; Melin, S; Montero, AJ; Poklepovic, A; Schuster, S; Smith, C; Soliman, H; Tang, SC; Tennant, L; Vahanian, N | 1 |
Chan, TH; Chen, T; Chow, LMC; Chow, TS; Choy, KY; He, Y; Li, P; Su, X; Sun, W; Wong, ILK; Yang, X | 1 |
Alonso Garcia, A; Caminero Cuevas, M; Costilla García, S; Fernández Rivero, G; Iglesias Agüeraa, A; Juan Rijo, G; Orduz Arena, A; Peña Vivas, J | 1 |
Alharbi, KH; Alharbi, W; Alhazza, IM; Alsalme, A; Bin Sharfan, II; Ebaid, H; Hassan, I; Khan, RA; Parveen, S | 1 |
Wu, KK | 1 |
Bieche, I; Castagnet, P; Chemlali, W; Lallemand, F; Meseure, D; Perrot-Applanat, M; Pocard, M; Vacher, S | 1 |
Li, F; Li, M; Liu, J; Ren, X; Wei, F; Wei, L; Zhu, S | 1 |
Borges, VF; Bruno, TC; Christenson, JL; Culp-Hill, R; D'Alessandro, A; Greene, LI; Richer, JK; Slansky, JE; Torkko, K | 1 |
Chen, SJ; Li, GS; Li, SY; Mai, HF; Wu, HC; Zhen, JX | 1 |
Boemer, F; Bours, V; Jerusalem, G; Josse, C; Leduc, S; Onesti, CE | 1 |
Alfano, RR; Budansky, Y; Pu, Y; Sordillo, LA; Sordillo, PP | 2 |
Boyle, NT; Collier, S; Connor, TJ; Harkin, A; Hevey, D; Hughes, MM; Kennedy, MJ; O'Dwyer, AM; Pertl, MM | 1 |
Amano, S; Enomoto, K; Fujisaki, S; Hara, Y; Hirano, T; Maeda, T; Nagashima, S; Sakurai, K; Suzuki, S; Tomita, R | 2 |
Borges, S; Döppler, HR; Storz, P | 1 |
Achilefu, S; Alfano, RR; Pratavieira, S; Pu, Y; Xu, B; Xue, J; Zhang, L | 1 |
Almendro, V; Carranza, A; Coveñas, R; Garcia-Recio, S; González-Ortega, A; Muñoz, M; Salinas-Martín, MV | 1 |
Bessede, A; Bodet, D; Debled, M; Eimer, S; Fallarino, F; Guillemin, GJ; Italiano, A; MacGrogan, G; Platten, M; Prendergast, GC; Puccetti, P; Soubeyran, I; Velasco, V; Veldhoen, M | 1 |
da Cunha Bianchi, PK; Gebrim, LH; Kfoury, JR; Salvadori, ML; Silva, RS | 1 |
Cao, ZG; Liu, FF; Qin, XB; Zhou, LL | 1 |
Ash, A; Caruso, D; Corona, G; Crivellari, D; Giordano, A; Lombardi, D; Miolo, G; Muraro, E; Rizzolio, F; Scalone, S | 1 |
Abdi, M; Amini, S; Ghaderi, B; Jalali, C; Roshani, D | 1 |
Chen, GY; Kuo, CH; Liao, HW; Liao, WC; Lin, CH; Wu, MS | 1 |
Brandsch, M; Budisa, N; Giese, C; Lepthien, S; Lilie, H; Metzner, L | 1 |
Bom, AP; Cordeiro, Y; Ferraz, D; Freitas, MS; Gomes, AM; Moreira, FS; Sanches, D; Silva, JL; Valente, AP | 1 |
Amano, S; Enomoto, K; Kitajima, A; Matsuo, S; Sakurai, K; Tani, M | 1 |
Carpenter, JS; Milata, J; Moser, L; Ryker, K; Schneider, B; Skaar, T; Storniolo, AM; Unverzagt, F; Von Ah, D; Wu, J; Yu, M | 1 |
Amano, S; Enomoto, K; Sakurai, K | 1 |
Alfano, RR; Pu, Y; Savage, HE; Schantz, SP; Tang, GC; Wang, WB | 1 |
Babu, E; Coothankandaswamy, V; Elangovan, S; Ganapathy, V; Gnanaprakasam, JP; Gurav, A; Karunakaran, S; Periyasamy-Thandavan, S; Prasad, PD; Ramachandran, S; Schoenlein, PV; Singh, N; Thangaraju, M | 1 |
Ali-Fehmi, R; Bandyopadhyay, S; Chakraborty, PK; Chugani, DC; Janabi, MZ; Juhász, C; Mangner, TJ; Mittal, S; Muzik, O; Nahleh, Z; Zitron, I | 1 |
Alfano, RR; Pu, Y; Wang, W; Yang, Y | 1 |
Finney, M; Harding, KG; Iorwerth, A; Jones, PW; Taylor, DM; Webster, D; Williams, DR | 1 |
Barber, MC; Gow, IF; Shennan, DB; Thomson, J; Travers, MT | 1 |
CURTIS, MR; DUNNING, WF; MAUN, ME | 1 |
Arrowsmith, CH; Ayed, A; Chakrabartty, A; Laister, R; Liao, JC; Lu, Y; Mark, WY; Szymczyna, B | 1 |
Frankenne, F; Kersemans, V; Labied, S; Noël, A; Oltenfreiter, R; Slegers, G; Staelens, L; Van de Wiele, C | 1 |
Banerjee, T; DuHadaway, J; Hou, DY; Johnson, M; Mellor, AL; Muller, AJ; Munn, DH; Prendergast, GC; Sharma, MD | 1 |
Balbín, M; Ferrando, AA; Fueyo, A; Hannon, GJ; López-Otín, C; Pendás, AM; Vizoso, F | 1 |
Dogasaki, C; Fukuoka, H; Kikuchi, K; Mori, M; Nishizawa, M; Ojika, M; Sahara, H; Sato, N; Takahashi, N | 1 |
Pham, HT; Ruediger, R; Walter, G | 1 |
Campbell, IT; Harvie, MN; Howell, A; Thatcher, N | 1 |
von Werder, K | 1 |
Bell, ED | 1 |
Basu, TK | 1 |
Knapp, A; Teichmann, E; Teichmann, W | 1 |
Bell, ED; Bulbrook, RD; Hayward, JL; Tong, D | 1 |
Brown, RR | 1 |
Howell, MA | 1 |
Raub, W | 1 |
Cangiano, C; Cascino, A; Ceci, F; Laviano, A; Mulieri, M; Muscaritoli, M; Rossi-Fanelli, F | 1 |
Bloomer, WD; Brown, RR; Dalton, J; Kalnicki, S; Lee, CM; Lehrer, S; Lipsztein, R; Song, HK | 1 |
Dickerson, JW; Poulter, JM; White, WF | 1 |
Rose, DP | 3 |
Bahn, RC; Silverstein, MN; Wakim, KG | 1 |
McGinty, F; Rose, DP | 1 |
Böttcher, RF; Wolff, H | 1 |
Brown, RR; Fahl, WE; Liskowski, L; Rose, DP | 1 |
Brown, RR; Leklem, JE | 1 |
Brown, RR; Carlson, IH; Davis, HL; Leklem, J | 1 |
Randall, ZC; Rose, DP | 3 |
Brown, RR; DeGeorge, FV | 1 |
Bell, EM; Bulbrook, RD; Hayward, JL; Mainwaring, WI; Tong, D | 1 |
Galt, RM; Knock, FE; Oester, YT; Renaud, OV; Sylvester, R | 1 |
5 review(s) available for tryptophan and Breast Neoplasms
Article | Year |
---|---|
Involvement of the kynurenine pathway in breast cancer: updates on clinical research and trials.
Topics: Breast Neoplasms; Female; Humans; Kynurenine; Tryptophan | 2023 |
Cytoguardin: A Tryptophan Metabolite against Cancer Growth and Metastasis.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Cyclooxygenase 2; Fibroblasts; Humans; Liver Neoplasms; Matrix Metalloproteinases; Mice; Neoplasm Metastasis; Neoplasms; Pancreatic Neoplasms; Serotonin; Tryptophan | 2021 |
[Hormonal therapy of metastizing breast cancer].
Topics: Adrenalectomy; Adult; Age Factors; Androgens; Breast Neoplasms; Castration; Culture Techniques; Estrogens; Female; Growth Hormone; Hormones; Humans; Hydrocortisone; Hypophysectomy; Middle Aged; Neoplasm Metastasis; Palliative Care; Prolactin; Receptors, Cell Surface; Sex Chromatin; Tryptophan | 1976 |
Significance of vitamins in cancer.
Topics: Antineoplastic Agents; Ascorbic Acid; Bone Neoplasms; Brain Neoplasms; Breast Neoplasms; Bronchial Neoplasms; Humans; Neoplasms; Nutritional Physiological Phenomena; Tryptophan; Vitamin A; Vitamin B Complex; Vitamin B Deficiency; Vitamins | 1976 |
Aspects of tryptophan metabolism in health and disease: a review.
Topics: Brain; Breast Neoplasms; Contraceptives, Oral; Depression; Endocrine System Diseases; Female; Glucocorticoids; Humans; Kidney Neoplasms; Male; Nicotinic Acids; Prostatic Neoplasms; Pyridoxine; Ribonucleotides; Serotonin; Tryptophan; Urinary Bladder Neoplasms; Vitamin B 6 Deficiency | 1972 |
1 trial(s) available for tryptophan and Breast Neoplasms
Article | Year |
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Effect of Taxane Chemotherapy With or Without Indoximod in Metastatic Breast Cancer: A Randomized Clinical Trial.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Middle Aged; Prospective Studies; Taxoids; Tryptophan | 2021 |
82 other study(ies) available for tryptophan and Breast Neoplasms
Article | Year |
---|---|
Injectable Micelle-Incorporated Hydrogels for the Localized Chemo-Immunotherapy of Breast Tumors.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Chondroitin Sulfates; Delayed-Action Preparations; Deoxycytidine; Enzyme Inhibitors; Female; Gemcitabine; Hydrogels; Immunotherapy; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice, Inbred BALB C; Micelles; Neoplasm Metastasis; Poloxamer; Tryptophan; Tumor Microenvironment | 2021 |
Ru(II)/amino acid complexes inhibit the progression of breast cancer cells through multiple mechanism-induced apoptosis.
Topics: Animals; Apoptosis; BALB 3T3 Cells; Breast Neoplasms; Chlorocebus aethiops; Coordination Complexes; Female; Humans; Methionine; Mice; Neoplasm Proteins; Rubidium; Tryptophan; Vero Cells | 2022 |
Polymeric indoximod based prodrug nanoparticles with doxorubicin entrapment for inducing immunogenic cell death and improving the immunotherapy of breast cancer.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Doxorubicin; Female; Humans; Immunogenic Cell Death; Immunologic Factors; Immunotherapy; Mice; Nanoparticles; Polymers; Prodrugs; Tryptophan; Tumor Microenvironment; Vascular Endothelial Growth Factor A | 2022 |
Potential of blood-based biomarker approaches in endometrium and breast cancer: a case-control comparison study.
Topics: Biomarkers, Tumor; Breast Neoplasms; Case-Control Studies; Endometrial Neoplasms; Endometrium; Female; Humans; MicroRNAs; ROC Curve; Tryptophan | 2022 |
Synthesis of smart carriers based on tryptophan-functionalized magnetic nanoparticles and its application in 5-fluorouracil delivery.
Topics: Breast Neoplasms; Drug Carriers; Drug Delivery Systems; Female; Fluorouracil; HEK293 Cells; Humans; Magnetite Nanoparticles; Nanoparticles; Tryptophan | 2022 |
Tryptophan and Kynurenine Pathway Metabolites and Psychoneurological Symptoms Among Breast Cancer Survivors.
Topics: Breast Neoplasms; Cancer Survivors; Cross-Sectional Studies; Female; Humans; Kynurenine; Tryptophan | 2023 |
IDO blockade negatively regulates the CTLA-4 signaling in breast cancer cells.
Topics: Animals; Breast Neoplasms; CTLA-4 Antigen; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Signal Transduction; Tryptophan | 2023 |
In Vitro 3D Spheroid Model Preserves Tumor Microenvironment of Hot and Cold Breast Cancer Subtypes.
Topics: Breast Neoplasms; Cell Line, Tumor; Female; Humans; Leukocytes, Mononuclear; Spheroids, Cellular; Tryptophan; Tumor Microenvironment | 2023 |
Polypyrrole/carbon dot nanocomposite as an electrochemical biosensor for liquid biopsy analysis of tryptophan in the human serum of normal and breast cancer women.
Topics: Biosensing Techniques; Breast Neoplasms; Carbon; Electrochemical Techniques; Electrodes; Female; Graphite; Humans; Nanocomposites; Polymers; Pyrroles; Tryptophan | 2023 |
Regulation of IDO2 by the Aryl Hydrocarbon Receptor (AhR) in Breast Cancer.
Topics: Breast Neoplasms; Cell Differentiation; Female; Humans; Immune Tolerance; Indoleamine-Pyrrole 2,3,-Dioxygenase; Receptors, Aryl Hydrocarbon; Tryptophan; Tumor Microenvironment | 2023 |
Common alterations in plasma free amino acid profiles and gut microbiota-derived tryptophan metabolites of five types of cancer patients.
Topics: Amino Acids; Arginine; Breast Neoplasms; Female; Gastrointestinal Microbiome; Humans; Tryptophan; Tumor Microenvironment | 2023 |
Selective inhibition of indoleamine and tryptophan 2,3-dioxygenases: Comparative study on kynurenine pathway in cell lines via LC-MS/MS-based targeted metabolomics.
Topics: Breast Neoplasms; Cell Line; Chromatography, Liquid; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Tandem Mass Spectrometry; Tryptophan; Tryptophan Oxygenase | 2024 |
Tryptophan metabolism regulates inflammatory macrophage polarization as a predictive factor for breast cancer immunotherapy.
Topics: Breast Neoplasms; CD8-Positive T-Lymphocytes; Female; Humans; Immunotherapy; Macrophages; Tryptophan; Tumor Microenvironment | 2023 |
Application of the optimized and validated LC-MS method for simultaneous quantification of tryptophan metabolites in culture medium from cancer cells.
Topics: Acetaldehyde; Breast Neoplasms; Cell Line, Tumor; Chromatography, High Pressure Liquid; Culture Media; Female; Humans; Kynurenic Acid; Limit of Detection; Metabolic Networks and Pathways; Metabolomics; Ovarian Neoplasms; Tandem Mass Spectrometry; Tryptophan | 2019 |
Carbidopa Alters Tryptophan Metabolism in Breast Cancer and Melanoma Cells Leading to the Formation of Indole-3-Acetonitrile, a Pro-Proliferative Metabolite.
Topics: Breast Neoplasms; Carbidopa; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromatography, High Pressure Liquid; Female; Humans; Indoles; Melanoma; Skin Neoplasms; Spectrometry, Mass, Electrospray Ionization; Tryptophan | 2019 |
4,5-Disubstituted 1,2,3-triazoles: Effective Inhibition of Indoleamine 2,3-Dioxygenase 1 Enzyme Regulates T cell Activity and Mitigates Tumor Growth.
Topics: Animals; Antineoplastic Agents, Immunological; Breast Neoplasms; Carcinoma, Ehrlich Tumor; Cell Line, Tumor; Drug Screening Assays, Antitumor; Enzyme Assays; Female; HEK293 Cells; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inhibitory Concentration 50; Kynurenine; Metabolic Networks and Pathways; Mice; Molecular Docking Simulation; Primary Cell Culture; Recombinant Proteins; T-Lymphocytes, Cytotoxic; Triazoles; Tryptophan; Tryptophan Oxygenase; Tumor Escape | 2019 |
Eliciting an immune hot tumor niche with biomimetic drug-based multi-functional nanohybrids augments immune checkpoint blockade-based breast cancer therapy.
Topics: Animals; Biomimetic Materials; Breast Neoplasms; Female; Humans; MCF-7 Cells; Mice, Inbred BALB C; Nanoparticles; Oxaliplatin; Tryptophan; Tumor Microenvironment; Xenograft Model Antitumor Assays | 2020 |
Gene expression of indoleamine and tryptophan dioxygenases and three long non-coding RNAs in breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Breast Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Indoles; Kynurenine; Metabolic Networks and Pathways; MicroRNAs; Middle Aged; RNA, Long Noncoding; Tryptophan; Tryptophan Oxygenase | 2020 |
Disruption of SND1-MTDH Interaction by a High Affinity Peptide Results in SND1 Degradation and Cytotoxicity to Breast Cancer Cells
Topics: Animals; Breast Neoplasms; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Surface Display Techniques; Down-Regulation; Endonucleases; Female; Humans; Membrane Proteins; Mice, Inbred BALB C; Mice, Nude; Models, Biological; Peptides; Protein Binding; Proteolysis; RNA-Binding Proteins; Tryptophan | 2021 |
[L-tryptophan as dietetic supplement and treatment for hot flashes, astenia, and insomnia in cancer patients].
Topics: Asthenia; Breast Neoplasms; Dietary Supplements; Female; Hot Flashes; Humans; Male; Prostatic Neoplasms; Quality of Life; Sleep Initiation and Maintenance Disorders; Treatment Outcome; Tryptophan; Uterine Cervical Neoplasms | 2021 |
Bioactive Tryptophan-Based Copper Complex with Auxiliary β-Carboline Spectacle Potential on Human Breast Cancer Cells: In Vitro and In Vivo Studies.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Carbolines; Cell Line; Cell Line, Tumor; Comet Assay; Copper; DNA Damage; Female; Glutathione; HEK293 Cells; Hep G2 Cells; Humans; Lipid Peroxidation; MCF-7 Cells; Oxidative Stress; Rats; Reactive Oxygen Species; Tryptophan; Zinc | 2021 |
High AHR expression in breast tumors correlates with expression of genes from several signaling pathways namely inflammation and endogenous tryptophan metabolism.
Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Cell Line, Tumor; Estrogen Receptor alpha; Female; Humans; Inflammation; Middle Aged; Real-Time Polymerase Chain Reaction; Receptors, Aryl Hydrocarbon; RNA, Messenger; Signal Transduction; Tryptophan | 2018 |
High Indoleamine 2,3-Dioxygenase Is Correlated With Microvessel Density and Worse Prognosis in Breast Cancer.
Topics: Adult; Aged; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Coculture Techniques; Endoglin; Female; Human Umbilical Vein Endothelial Cells; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Microvessels; Middle Aged; Neovascularization, Pathologic; Prognosis; Tryptophan | 2018 |
A Role for Tryptophan-2,3-dioxygenase in CD8 T-cell Suppression and Evidence of Tryptophan Catabolism in Breast Cancer Patient Plasma.
Topics: Breast Neoplasms; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Female; Humans; Kynurenine; Lymphocytes, Tumor-Infiltrating; Tryptophan; Tryptophan Oxygenase | 2019 |
Microarray-based analysis of whole-genome DNA methylation profiling in early detection of breast cancer.
Topics: Adult; Aged; Biomarkers, Tumor; Breast Neoplasms; Databases, Nucleic Acid; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Early Detection of Cancer; Female; Gene Expression Regulation, Neoplastic; Genome, Human; Homeodomain Proteins; Humans; Insulin-Like Growth Factor I; MCF-7 Cells; Middle Aged; Oligonucleotide Array Sequence Analysis; Phthalimides; Signal Transduction; Transcription Factors; Transcriptome; Tryptophan; Up-Regulation | 2019 |
Tryptophan catabolism increases in breast cancer patients compared to healthy controls without affecting the cancer outcome or response to chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Breast Neoplasms; Case-Control Studies; Cell Differentiation; Chemotherapy, Adjuvant; Female; Humans; Immunosuppressive Agents; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kaplan-Meier Estimate; Kynurenine; Middle Aged; Proportional Hazards Models; Prospective Studies; T-Lymphocytes; Tandem Mass Spectrometry; Treatment Outcome; Tryptophan | 2019 |
Optical spectral fingerprints of tissues from patients with different breast cancer histologies using a novel fluorescence spectroscopic device.
Topics: Adult; Aged; Area Under Curve; Breast; Breast Neoplasms; Carcinoma; Collagen; Discriminant Analysis; Elastin; Female; Humans; Middle Aged; Optical Imaging; ROC Curve; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 2013 |
C-reactive protein predicts fatigue independently of depression in breast cancer patients prior to chemotherapy.
Topics: Biomarkers; Breast Neoplasms; C-Reactive Protein; Cytokines; Depression; Fatigue; Female; Humans; Inflammation; Kynurenine; Middle Aged; Tryptophan | 2013 |
[Indoleamine 2, 3-dioxygenase activity during neoadjuvant chemotherapy in patients with breast cancer].
Topics: Adult; Aged; Breast Neoplasms; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Tryptophan | 2013 |
A combination treatment with DNA methyltransferase inhibitors and suramin decreases invasiveness of breast cancer cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Decitabine; DNA Methylation; Enzyme Inhibitors; Female; Humans; Immunoblotting; Immunohistochemistry; Immunoprecipitation; Mice; Mice, Nude; Neoplasm Invasiveness; Phthalimides; Reverse Transcriptase Polymerase Chain Reaction; Suramin; Tryptophan; Xenograft Model Antitumor Assays | 2014 |
Tryptophan as the fingerprint for distinguishing aggressiveness among breast cancer cell lines using native fluorescence spectroscopy.
Topics: Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Image Interpretation, Computer-Assisted; Spectrometry, Fluorescence; Support Vector Machine; Tryptophan | 2014 |
The neurokinin-1 receptor antagonist aprepitant is a promising candidate for the treatment of breast cancer.
Topics: Antineoplastic Agents; Aprepitant; Breast Neoplasms; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; MCF-7 Cells; Morpholines; Neurokinin-1 Receptor Antagonists; Piperidines; Receptors, Neurokinin-1; Substance P; Tryptophan | 2014 |
[Indoleamine 2,3-dioxygenase activity in breast cancer patients with local recurrence or distant metastases].
Topics: Adult; Aged; Breast Neoplasms; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Tryptophan | 2014 |
Differences in fluorescence profiles from breast cancer tissues due to changes in relative tryptophan content via energy transfer: tryptophan content correlates with histologic grade and tumor size but not with lymph node metastases.
Topics: Aged; Breast Neoplasms; Case-Control Studies; Female; Humans; Lymph Nodes; Lymphatic Metastasis; Middle Aged; NAD; Optical Imaging; Spectrometry, Fluorescence; Tryptophan | 2014 |
Accumulation of an endogenous tryptophan-derived metabolite in colorectal and breast cancers.
Topics: Breast Neoplasms; Colorectal Neoplasms; Humans; Tryptophan | 2015 |
Effect of the association of 1-methyl-DL-tryptophan with paclitaxel on the expression of indoleamine 2,3-dioxygenase in cultured cancer cells from patients with breast cancer.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Paclitaxel; Tryptophan; Tumor Cells, Cultured | 2015 |
Tryptophan-induced pathogenesis of breast cancer.
Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Breast Neoplasms; Case-Control Studies; CD4-Positive T-Lymphocytes; Depression; Female; Humans; Interleukin-10; Middle Aged; RNA, Messenger; Tryptophan | 2015 |
Pharmacometabolomics study identifies circulating spermidine and tryptophan as potential biomarkers associated with the complete pathological response to trastuzumab-paclitaxel neoadjuvant therapy in HER-2 positive breast cancer.
Topics: Adult; Aged; Antineoplastic Agents; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Least-Squares Analysis; Middle Aged; Neoadjuvant Therapy; Paclitaxel; Pharmacogenetics; Receptor, ErbB-2; ROC Curve; Spermidine; Tandem Mass Spectrometry; Trastuzumab; Treatment Outcome; Tryptophan; Young Adult | 2016 |
Association of XRCC1 Trp194 allele with risk of breast cancer, and Ki67 protein status in breast tumor tissues.
Topics: Adult; Alleles; Breast Neoplasms; Cross-Sectional Studies; DNA-Binding Proteins; Female; Genetic Predisposition to Disease; Humans; Iran; Ki-67 Antigen; Middle Aged; Polymorphism, Single Nucleotide; Tryptophan; X-ray Repair Cross Complementing Protein 1 | 2016 |
Development of a Postcolumn Infused-Internal Standard Liquid Chromatography Mass Spectrometry Method for Quantitative Metabolomics Studies.
Topics: Breast Neoplasms; Calibration; Chromatography, Liquid; Female; Flow Injection Analysis; Humans; Metabolomics; Observer Variation; Phenylalanine; Principal Component Analysis; Reference Standards; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tryptophan | 2017 |
Intracellular uptake and inhibitory activity of aromatic fluorinated amino acids in human breast cancer cells.
Topics: Amino Acid Transport System L; Breast Neoplasms; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; p-Fluorophenylalanine; Stereoisomerism; Structure-Activity Relationship; Time Factors; Tryptophan; Tumor Cells, Cultured | 2008 |
The p53 core domain is a molten globule at low pH: functional implications of a partially unfolded structure.
Topics: Acids; Breast Neoplasms; Cell Compartmentation; Cell Line, Tumor; Female; Humans; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Nuclear Magnetic Resonance, Biomolecular; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Solvents; Transfection; Tryptophan; Tumor Suppressor Protein p53 | 2010 |
[Indoleamine 2,3-dioxygenase activity during chemotherapy in patients with breast cancer].
Topics: Adult; Age Factors; Breast Neoplasms; Chromatography, High Pressure Liquid; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Middle Aged; Tryptophan | 2009 |
Evaluating the role of serotonin on neuropsychological function after breast cancer using acute tryptophan depletion.
Topics: Adult; Breast Neoplasms; Female; Humans; Middle Aged; Neuropsychological Tests; Serotonin; Tryptophan | 2012 |
[Indoleamine 2,3-dioxygenase activity during chemotherapy or hormone therapy in patients with breast cancer].
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Chromatography, High Pressure Liquid; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Letrozole; Middle Aged; Nitriles; Paclitaxel; Triazoles; Tryptophan | 2010 |
Native fluorescence spectroscopic evaluation of chemotherapeutic effects on malignant cells using nonnegative matrix factorization analysis.
Topics: Algorithms; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Female; Flavins; Humans; NAD; Reference Standards; Sensitivity and Specificity; Spectrometry, Fluorescence; Tretinoin; Tryptophan | 2011 |
SLC6A14 (ATB0,+) protein, a highly concentrative and broad specific amino acid transporter, is a novel and effective drug target for treatment of estrogen receptor-positive breast cancer.
Topics: Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Autophagy; Breast Neoplasms; Female; Humans; Mice; Molecular Targeted Therapy; Receptors, Estrogen; Transplantation, Heterologous; Tryptophan; Tumor Cells, Cultured | 2011 |
Tryptophan metabolism in breast cancers: molecular imaging and immunohistochemistry studies.
Topics: Adult; Breast Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kinetics; Large Neutral Amino Acid-Transporter 1; Middle Aged; Positron-Emission Tomography; Tryptophan; Tryptophan Hydroxylase | 2012 |
Stokes shift spectroscopic analysis of multifluorophores for human cancer detection in breast and prostate tissues.
Topics: Biomarkers; Breast Neoplasms; Collagen; Female; Humans; Male; NAD; Optical Imaging; Prostatic Neoplasms; ROC Curve; Sensitivity and Specificity; Tryptophan | 2013 |
Using wound fluid analyses to identify trace element requirements for efficient healing.
Topics: Breast Neoplasms; Copper; Exudates and Transudates; Female; Histidine; Humans; Hydrogen-Ion Concentration; Mastectomy; Monitoring, Physiologic; Potentiometry; Reference Values; Time Factors; Tryptophan; Wound Healing; Zinc | 2001 |
Indoleamine 2,3-dioxygenase activity and L-tryptophan transport in human breast cancer cells.
Topics: Binding, Competitive; Breast Neoplasms; Cell Line, Tumor; Culture Media, Conditioned; Humans; Interferon-gamma; Norbornanes; Receptors, Estrogen; RNA, Messenger; Tryptophan; Tryptophan Oxygenase | 2004 |
The effect of added dietary tryptophane on the occurrence of diethylstilbestrol-induced mammary cancer in rats.
Topics: Animals; Breast Neoplasms; Cell Transformation, Neoplastic; Diet; Diethylstilbestrol; Neoplasms; Rats; Tryptophan | 1950 |
Characterization of segments from the central region of BRCA1: an intrinsically disordered scaffold for multiple protein-protein and protein-DNA interactions?
Topics: Apoptosis; Biophysical Phenomena; Biophysics; BRCA1 Protein; Breast Neoplasms; Cell Cycle; Circular Dichroism; DNA; DNA Repair; Dose-Response Relationship, Drug; Humans; Magnetic Resonance Spectroscopy; Models, Genetic; Mutation, Missense; Polymerase Chain Reaction; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Tertiary; Transcription, Genetic; Tryptophan; Tumor Suppressor Protein p53 | 2005 |
Tryptophane-based biphenylsulfonamide matrix metalloproteinase inhibitors as tumor imaging agents.
Topics: Animals; Biphenyl Compounds; Breast Neoplasms; Cell Line, Tumor; Humans; Iodine Radioisotopes; Matrix Metalloproteinase Inhibitors; Mice; Mice, Nude; Neoplasms; Protease Inhibitors; Sulfonamides; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Tryptophan | 2005 |
Inhibition of indoleamine 2,3-dioxygenase in dendritic cells by stereoisomers of 1-methyl-tryptophan correlates with antitumor responses.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Dendritic Cells; Drug Synergism; Female; HeLa Cells; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Paclitaxel; Stereoisomerism; Tryptophan | 2007 |
Functional analysis of a p21WAF1,CIP1,SDI1 mutant (Arg94 --> Trp) identified in a human breast carcinoma. Evidence that the mutation impairs the ability of p21 to inhibit cyclin-dependent kinases.
Topics: Arginine; Base Sequence; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Cycle; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; DNA Primers; Female; Humans; Molecular Sequence Data; Oncogene Proteins; Point Mutation; Protein Binding; Structure-Activity Relationship; Tryptophan | 1996 |
[Substance isolated from the kelp rhizoid identified as L-tryptophan shows high inhibition of breast cancer].
Topics: Antineoplastic Agents; Breast Neoplasms; Humans; Seaweed; Tryptophan; Tumor Cells, Cultured | 2000 |
Disruption of protein phosphatase 2A subunit interaction in human cancers with mutations in the A alpha subunit gene.
Topics: Amino Acid Sequence; Arginine; Aspartic Acid; Breast Neoplasms; Female; Glutamic Acid; Glycine; Humans; Lung Neoplasms; Melanoma; Molecular Sequence Data; Neoplasms; Peptide Fragments; Phosphoprotein Phosphatases; Point Mutation; Protein Binding; Protein Phosphatase 2; Protein Structure, Secondary; Tryptophan | 2001 |
Acceptability and tolerance of a low tyrosine and phenylalanine diet in patients with advanced cancer -- a pilot study.
Topics: Adult; Aged; Breast Neoplasms; Depression; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Nutritional Status; Phenylalanine; Pilot Projects; Quality of Life; Treatment Outcome; Tryptophan; Tyrosine | 2002 |
Tryptophan metabolism in Japanese and British women and its relationship to endogenous steroid levels.
Topics: 3-Hydroxyanthranilic Acid; Asian People; Breast Neoplasms; Estradiol; Female; Hormones; Humans; Hydrocortisone; Japan; Kynurenine; Menopause; Tryptophan; United Kingdom; White People; Xanthurenates | 1978 |
[Tryptophan metabolism in breast carcinoma].
Topics: Aged; Breast Neoplasms; Female; Humans; Kynurenine; Menopause; Middle Aged; Postoperative Complications; Tryptophan; Xanthurenates | 1976 |
Tryptophan metabolism and recurrence rates of patients with breast cancer after mastectomy.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Age Factors; Aged; Breast Neoplasms; Female; Humans; Kynurenine; Mastectomy; Menopause; Middle Aged; Time Factors; Tryptophan | 1975 |
Twenty years of tryptophan studies in humans.
Topics: Breast Neoplasms; Female; Humans; Hydrocortisone; Kynurenine; Liver; Neoplasm Metastasis; Tryptophan | 1975 |
The association between colorectal cancer and breast cancer.
Topics: Breast Neoplasms; Colonic Neoplasms; Diet; Dietary Fats; Female; Food; Humans; Male; Rectal Neoplasms; Risk; Transients and Migrants; Tryptophan; United States | 1976 |
From the National Institutes of Health.
Topics: Antineoplastic Combined Chemotherapy Protocols; Aortic Aneurysm; Breast Neoplasms; Eosinophilia; Female; Humans; Hypertension; Middle Aged; Muscles; Mutation; Pain; Pregnancy; Pregnancy Complications, Cardiovascular; Procollagen; Syndrome; Tamoxifen; Tryptophan | 1991 |
Plasma and CSF tryptophan in cancer anorexia.
Topics: Aged; Amino Acids; Anorexia; Breast Neoplasms; Feeding and Eating Disorders; Female; Humans; Lung Neoplasms; Male; Middle Aged; Tryptophan | 1990 |
Tryptophan metabolism in women with breast cancer.
Topics: Breast Neoplasms; Female; Humans; Kynurenine; Receptors, Estrogen; Receptors, Progesterone; Tryptophan | 1988 |
Tryptophan metabolism in patients with breast cancer.
Topics: Breast Neoplasms; Female; Fibrocystic Breast Disease; Humans; Tryptophan | 1985 |
Tryptophan metabolism in carcinoma of the breast.
Topics: Adult; Aged; Breast Neoplasms; Chromatography, Thin Layer; Estrogens; Female; Humans; Kynurenine; Middle Aged; ortho-Aminobenzoates; Tryptophan; Xanthurenates | 1967 |
Tryptophan metabolites in hypoglycemia associated with neoplasia.
Topics: Adenoma, Islet Cell; Adrenal Gland Neoplasms; Adult; Breast Neoplasms; Female; Humans; Hypoglycemia; Male; Middle Aged; Neoplasm Metastasis; Tryptophan | 1966 |
The influence of adrenocortical hormones and vitamins upon tryptophan metabolism in man.
Topics: Adrenocorticotropic Hormone; Adult; Benzoates; Breast Neoplasms; Female; Humans; Hydrocortisone; Kynurenine; Liver; Male; Niacinamide; Pyridoxine; Riboflavin; Stimulation, Chemical; Stress, Physiological; Tryptophan; Tryptophan Oxygenase; Xanthurenates | 1968 |
[Significance of tryptophan-perchloric acid reaction in malignant tumors].
Topics: Appendicitis; Breast Neoplasms; Bronchial Neoplasms; Cholelithiasis; Colonic Neoplasms; Esophageal Neoplasms; Hernia, Inguinal; Humans; Indicators and Reagents; Neoplasms; Osteomyelitis; Perchlorates; Rectal Neoplasms; Stomach Neoplasms; Stomach Ulcer; Tryptophan; Tuberculosis, Pulmonary | 1971 |
Tryptophan metabolism and corticosteroids in breast cancer.
Topics: Adult; Aged; Breast Neoplasms; Female; Humans; Hydrocortisone; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Tryptophan | 1974 |
Proceedings: Normal and pathological factors which affect tryptophan metabolism in man.
Topics: Breast Neoplasms; Female; Humans; Kynurenine; Pregnancy; Tryptophan; Tryptophan Oxygenase | 1972 |
Tryptophan metabolism in breast cancer. Correlation with urinary steroid excretion.
Topics: 17-Hydroxycorticosteroids; Adult; Aged; Aminohippuric Acids; Androsterone; Breast Neoplasms; Etiocholanolone; Female; Humans; Kynurenic Acid; Kynurenine; Middle Aged; ortho-Aminobenzoates; Tryptophan; Xanthurenates | 1973 |
Reassessment of tryptophan metabolism in breast cancer five years after an initial study.
Topics: Adult; Age Factors; Aged; Alcohols; Amino Acids; Breast Neoplasms; Castration; Chromatography, Ion Exchange; Chromatography, Thin Layer; Endocrine System Diseases; Female; Follow-Up Studies; Humans; Mastectomy; Middle Aged; ortho-Aminobenzoates; Phenylbutyrates; Time Factors; Tryptophan; Xanthurenates | 1973 |
Influence of the loading dose on the demonstration of abnormal tryptophan metabolism by cancer patients.
Topics: Administration, Oral; Adolescent; Adult; Animals; Breast Neoplasms; Bronchial Neoplasms; Carcinoma; Female; Humans; Male; Middle Aged; Time Factors; Tryptophan; Uterine Cervical Neoplasms | 1973 |
Tryptophan metabolism in early and advanced breast cancer and carcinoma of the cervix.
Topics: Administration, Oral; Adult; Aged; Bone Neoplasms; Breast Neoplasms; Carcinoma; Female; Humans; Kynurenine; Lymphatic Metastasis; Mastectomy; Middle Aged; Neoplasm Metastasis; ortho-Aminobenzoates; Pleural Effusion; Tryptophan; Uterine Cervical Neoplasms; Xanthurenates | 1972 |
Differences in tryptophan metabolism between breast cancer patients with and without cancer at other sites.
Topics: Bone Neoplasms; Brain Neoplasms; Breast Neoplasms; Female; Humans; Kynurenic Acid; Kynurenine; Lung Neoplasms; Male; Neoplasm Metastasis; Ovarian Neoplasms; Tryptophan; Urinary Bladder Neoplasms; Xanthurenates | 1970 |
Relationships between excretion of steroid hormones and tryptophan metabolites in patients with breast cancer.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Administration, Oral; Adult; Age Factors; Breast Neoplasms; Chromatography, Thin Layer; Female; Fluorescence; Humans; Hydrolases; Kynurenine; Middle Aged; Neurospora; ortho-Aminobenzoates; Tryptophan; Xanthurenates | 1971 |
The influence of sex, age and breast cancer on tryptophan metabolism.
Topics: Age Factors; Breast Neoplasms; Estrogens; Female; Kynurenine; Menstruation; ortho-Aminobenzoates; Ovulation; Sex Factors; Tryptophan; Xanthurenates | 1967 |
Cancer chemotherapy aimed at potential cell regulators.
Topics: Arsenicals; Breast Neoplasms; Female; Humans; Hyperbaric Oxygenation; Iodoacetates; Neoplasms; Sulfhydryl Compounds; Tryptophan | 1969 |