tryptophan has been researched along with Bipolar Disorder in 183 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 96 (52.46) | 18.7374 |
| 1990's | 20 (10.93) | 18.2507 |
| 2000's | 27 (14.75) | 29.6817 |
| 2010's | 25 (13.66) | 24.3611 |
| 2020's | 15 (8.20) | 2.80 |
| Authors | Studies |
|---|---|
| Benedetti, F; Bollettini, I; Colombo, C; Comai, S; Lorenzi, C; Melloni, E; Poletti, S; Vai, B; Valtorta, F; Zanardi, R | 1 |
| Giltay, EJ; Hebbrecht, K; Morrens, M; Sabbe, B; van den Ameele, S; van Nuijs, ALN | 1 |
| Bartoli, F; Callovini, T; Carrà, G; Cavaleri, D; Cioni, RM; Crocamo, C; Misiak, B; Savitz, JB | 2 |
| Coico, R; Pato, M; Sales, PMG; Schrage, E | 1 |
| Coppens, V; de Boer, P; Fransen, E; Lai, FY; Morrens, M; Sabbe, B; Schuermans, J; Timmers, M; van den Ameele, S; van Diermen, L; van Nuijs, AL; Verkerk, R | 1 |
| Aggio, V; Benedetti, F; Colombo, C; Comai, S; Melloni, E; Poletti, S; Valtorta, F | 1 |
| Ballard, ED; Deng, ZD; Farmer, CA; Gold, PW; Henter, ID; Kadriu, B; Kraus, C; Machado-Vieira, R; Moaddel, R; Park, LT; Shovestul, B; Yuan, P; Zarate, CA | 1 |
| Deng, WF; Guo, YY; He, FS; Lai, WT; Li, MZ; Liu, TB; Liu, YH; Rong, H; Tan, ZM; Wang, MB; Wang, S; Xie, XH; Xu, D; Xu, SX; Yang, QF; Yang, YJ; Ye, SW; Zhang, YL; Zhao, J | 1 |
| Benevenuto, D; Fries, GR; Kahlon, R; Kazimi, IF; Kurian, S; Quevedo, J; Saxena, J; Saxena, K; Scaini, G; Soares, JC; Valvassori, SS; Zeni, CP | 1 |
| Brundin, L; Erhardt, S; Khanlarkhani, N; Landén, M; Pålsson, E; Schwieler, L; Sellgren, CM; Trepci, A | 1 |
| Bartoli, F; Callovini, T; Carrà, G; Cavaleri, D; Cioni, RM; Crocamo, C | 1 |
| Coppens, V; De Picker, L; Giltay, EJ; Hebbrecht, K; Morrens, M; Skorobogatov, K | 1 |
| Kopra, E; Mondelli, V; Nikkheslat, N; Pariante, C | 1 |
| Miller, BJ; Wang, AK | 1 |
| Bengesser, SA; Birner, A; Dalkner, N; Fellendorf, FT; Fuchs, D; Hamm, C; Herzog-Eberhard, S; Hörmanseder, C; Kainzbauer, N; Maget, A; Mangge, H; Mansur, RB; McIntyre, RS; Moll, N; Pilz, R; Platzer, M; Queissner, R; Rauch, P; Reininghaus, EZ; Schütze, G; Schwarz, MJ; Zelzer, S | 1 |
| Bengesser, SA; Birner, A; Dalkner, N; Fellendorf, FT; Fuchs, D; Holasek, SJ; Kapfhammer, HP; Mangge, H; Painold, A; Platzer, M; Queissner, R; Reininghaus, B; Reininghaus, EZ | 1 |
| Can, A; Fuchs, D; Groer, M; Krishnamurthy, VB; Millett, CE; Mukherjee, D; Postolache, TT; Reider, A; Saunders, EFH | 1 |
| Fischer, CW; Jensen, E; Kousholt, BS; Larsen, ER; Liebenberg, N; Pereira, VS; Wegener, G | 1 |
| Bengesser, S; Birner, A; Dalkner, N; Fellendorf, F; Gorkiewicz, G; Halwachs, B; Holl, AK; Holzer, P; Kapfhammer, HP; Kashofer, K; Moll, N; Mörkl, S; Painold, A; Platzer, M; Queissner, R; Reininghaus, EZ; Schütze, G; Schwarz, MJ | 1 |
| Guadagno, E; Li, C; Ramamurthy, J; Trakadis, Y; Wang, A; Wang, C; Zhang, E | 1 |
| Amore, M; Baldessarini, RJ; Berardelli, I; Curto, M; Erbuto, D; Forte, A; Girardi, P; Innamorati, M; Lionetto, L; Montebovi, F; Pompili, M; Serafini, G; Seretti, ME; Simmaco, M | 1 |
| Shimizu, F; Takada, A; Takao, T | 1 |
| Chen, L; Li, H; Li, M; Liu, W; Ning, Y; Wang, C; Zhan, Y; Zheng, W; Zhou, Y | 1 |
| Agartz, I; Andreassen, OA; Bogdanov, M; Dieset, I; Djurovic, S; Hope, S; Jönsson, EG; Kaddurah-Daouk, R; Matson, W; Melle, I; Smeland, OB; Steen, NE; Vedal, TSJ | 1 |
| Bhat, M; Blennow, K; Cannon, TD; Engberg, G; Erhardt, S; Hultman, CM; Johansson, V; Kegel, M; Landén, M; Schwieler, L; Wetterberg, L; Zetterberg, H | 1 |
| Kasper, S | 1 |
| Badawy, A | 1 |
| Young, SN | 2 |
| Badawy, AA | 1 |
| Bengesser, SA; Birner, A; Fuchs, D; Geisler, S; Hecht, K; Kapfhammer, HP; Kattnig, F; Lackner, N; Mangge, H; McIntyre, RS; Reininghaus, B; Reininghaus, EZ; Unterweger, R; Zelzer, S | 1 |
| Anderson, G; Maes, M | 1 |
| Anderson, G; Bellivier, F; Geoffroy, PA; Jacob, A | 1 |
| Benedetti, F; Bollettini, I; Colombo, C; Grillitsch, D; Locatelli, C; Mazza, E; Myint, AM; Poletti, S; Schüetze, G; Schwarz, M | 1 |
| Bhat, M; Cannon, TD; Engberg, G; Erhardt, S; Hultman, CM; Johansson, V; Kegel, ME; Landén, M; Schuppe-Koistinen, I; Schwieler, L; Wetterberg, L | 1 |
| Bengesser, SA; Birner, A; Dalkner, N; Fellendorf, FT; Fuchs, D; Hamm, C; Herzog-Eberhard, S; Kapfhammer, HP; Maget, A; Mangge, H; Moll, N; Pilz, R; Platzer, M; Queissner, R; Rauch, P; Reininghaus, B; Reininghaus, EZ; Schütze, G; Schwarz, M; Zelzer, S | 1 |
| Holtmann, M; Poustka, F; Wöckel, L; Zepf, FD | 2 |
| Bjerkenstedt, L; Johansson, J; Persson, ML; Raita, J; Venizelos, N; Vumma, R; Wiesel, FA | 1 |
| Freitag, CM; Herpertz-Dahlmann, B; Poustka, F; Wöckel, L; Zepf, FD | 1 |
| Cooke, RG; Levitan, RD | 1 |
| Hoenders, R; Lake, J; Sarris, J | 1 |
| Ghanizadeh, A; Mohammadynejad, P; Saadat, I; Saadat, M | 1 |
| Deckersbach, T; Nierenberg, AA; Peters, AT; Sylvia, LG | 1 |
| Honig, A; Maes, M; Riedel, WJ; Sobczak, S; van Duinen, MA | 1 |
| Honig, A; Nicolson, NA; Riedel, WJ; Sobczak, S | 1 |
| Kurup, AR; Kurup, PA | 1 |
| Honig, A; Riedel, WJ; Schmitt, JA; Sobczak, S | 1 |
| Harrison, BJ; Nathan, PJ | 1 |
| BURGERMEISTER, JJ; DICK, P; GARONNE, G; GUGGISBERG, M; TISSOT, R | 1 |
| Christophe, A; De Vriese, SA; Helsdingen, RW; Honig, A; Maes, M; Riedel, WJ; Sobczak, S | 1 |
| Joyce, PR; Kennedy, MA; Luty, SE; McKenzie, JM; Miller, AL; Mulder, RT; Porter, RJ | 1 |
| Bell, CJ; Hood, SD; Nutt, DJ | 1 |
| Fekkes, D; Hoekstra, R; Loonen, AJ; Pepplinkhuizen, L; Tuinier, S; Verhoeven, WM | 1 |
| Kim, YK; Leonard, BE; Myint, AM; Park, SH; Scharpé, S; Steinbusch, HW; Verkerk, R | 1 |
| Applebaum, J; Bersudsky, Y; Klein, E | 1 |
| Cwik, M; Llenos, IC; Miller, CL; Walkup, J; Weis, S | 1 |
| Rubin, RT | 1 |
| Anokhina, IP; Gamaleia, NB | 1 |
| Korf, J; van den Burg, W; van den Hoofdakker, RH | 1 |
| Arató, M; Banki, CM; Papp, Z | 1 |
| Banki, CM | 1 |
| Anderson, GM; Cohen, DJ; Fairbanks, L; Gerner, RH; Hare, TA; Linnoila, M; Scheinin, M; Shaywitz, BA; Young, JG | 1 |
| Honoré, P; Larsen, OB; Møller, SE | 1 |
| Dunner, DL; Fieve, RR; Goodnick, PJ; Perel, JM | 1 |
| Brewerton, TD; Reus, VI | 1 |
| Honoré, P; Kirk, L; Møller, SE | 2 |
| Annable, L; Chouinard, G; Young, SN | 2 |
| Rubin, EH; Thomas, JM | 1 |
| Dam, H; Mellerup, ET; Rafaelsen, OJ | 1 |
| de Jong, JT; Thijssen, JH; van Praag, HM; Westenberg, HG | 1 |
| Diamond, JM; Ehrlich, BE | 1 |
| Baloh, RW; Dietz, J; Spooner, JW | 1 |
| Beitman, BD; Dunner, DL | 1 |
| Benyacoub, K; Bousquet, B; Cuche, H; Deniker, P; Dreux, C; Escande, C; Loo, H; Zarifian, E | 1 |
| Benkelfat, C; Ellenbogen, M; Hillel, J; Palmour, RM; Seletti, B; Young, SN | 1 |
| Watanabe, K | 1 |
| Alfano, M; Catalano, M; Lucca, A; Lucini, V; Smeraldi, E | 1 |
| Catalano, M; Lucca, A; Lucini, V; Smeraldi, E | 1 |
| Badawy, AA; Bradley, DM; Mokhtar, AS; Morgan, CJ | 1 |
| Cappiello, A; Heninger, GR; Malison, RT; McDougle, CJ; Price, LH; Sernyak, MJ | 1 |
| McTavish, SF; Reilly, JG; Young, AH | 1 |
| Carroll, BJ; Cassidy, F; Murry, E | 1 |
| Arun, P; Kurup, PA; Leelamma, S; Ravikumar, A | 1 |
| Howson, AL; Knott, VJ; Perugini, M; Ravindran, AV; Young, SN | 1 |
| Dunne, F; Hughes, JH; Young, AH | 1 |
| Shiah, IS; Yatham, LN | 1 |
| Van der Does, AJ | 1 |
| Barrett, C; Sharma, V | 1 |
| Alvarez, JC; Arnulf, I; Barbault, S; Benkelfat, C; Jouvent, R; Launay, JM; Leboyer, M; Perez-Diaz, F; Pointereau-Bellenger, A; Quintin, P; Varoquaux, O | 1 |
| Kirov, G; Lightman, SL; Lowry, CA; O'Donovan, MC; Oldfield, S; Owen, MJ; Stephens, M | 1 |
| Aberg-Wistedt, A; El-Khoury, A; Johnson, L; Mathé, AA; Stain-Malmgren, R | 1 |
| Gallagher, P; Hughes, JH; Young, AH | 1 |
| Aan Het Rot, M; Booij, I; Deutz, NE; Honig, A; Riedel, WJ; Sobczak, S | 1 |
| Ashton, CH; Hughes, JH; Marsh, VR; Young, AH | 1 |
| Leonard, BE | 1 |
| Sourkes, TL | 1 |
| Bohuon, C; Boulu, R; Poitou, P | 1 |
| Luchins, D | 1 |
| Annable, L; Chouinard, G; Kiriakos, RZ; Sourkes, TL; Young, SN | 1 |
| Annable, L; Chouinard, G; Sourkes, TL; Young, SN | 1 |
| Annable, L; Chouinard, G; Jones, BD; Young, SN | 1 |
| Paasche, I | 1 |
| Bunney, WE; Kopanda, RT; Murphy, DL | 1 |
| Cramer, H; Goodwin, FK; Post, RM | 1 |
| Campbell, IC; Costa, JL; Murphy, DL | 1 |
| Gaillard, JM; Tissot, R | 1 |
| Wirz-Justice, A | 1 |
| Boulu, R; Poitou, P | 1 |
| Chambers, CA; Naylor, GJ | 1 |
| Aksenova, IO | 1 |
| Adams, M; Chambers, C; Dick, P; Moody, JP; Naylor, GJ; Peet, M; Smith, A; Worrall, EP | 1 |
| Amdisen, A; Møller, SE | 1 |
| Garfinkel, PE; Stancer, HC; Warsh, JJ | 1 |
| Knapp, S; Mandell, AJ | 3 |
| Kirk, L; Møller, SE | 1 |
| Moody, JP; Naylor, GJ; Peet, M | 1 |
| Kishimoto, H | 1 |
| Bowers, MB; Heninger, GR | 1 |
| Boleaga, B; Castellanos, G; Eisenring, JJ; Estrada, E; Gaillard, JM; Hovaguimian, T; Hyde, A; Miranda, R; Tissot, R | 1 |
| Bech, P; Bock, E; Johannesen, M; Kirkegaard, C; Rafaelsen, OJ | 1 |
| Blazek, R; Francis, AF; Johnson, AL; Michalakeas, AC; Riley, GJ; Shaw, DM; Tidmarsh, SF | 1 |
| Tissot, R | 2 |
| Dunner, DL; Farkas, T; Fieve, RR | 1 |
| Fremming, KH; Kirk, L; Moller, SE | 1 |
| Dunner, DL; Fieve, RR; Gross, HA; Lafleur, D; Meltzer, HL | 1 |
| Lovett Doust, JW | 1 |
| Hullin, RP; Jerram, T | 1 |
| Garfinkel, PE; Sibony, D; Stancer, HC; Warsh, JJ | 1 |
| Dunner, DL; Fieve, RR | 1 |
| Burns, D; Frazer, A; Mendels, J; Stinnett, JL | 1 |
| Frazer, A; Mendels, J | 1 |
| Hewland, HR; Johnson, AL; Macsweeney, DA; Shaw, DM; Woolcock, NE | 1 |
| Moody, JP; Naylor, GJ; Peet, M; Walker, P; Worrall, EP | 1 |
| Kaneko, M; Kumashiro, H; Watanabe, K | 1 |
| Lucca, A; Lucini, V; Piatti, E; Ronchi, P; Smeraldi, E | 1 |
| Candito, M; Chambon, P; Darcourt, G; Iordache, A; Pringuey, D; Souêtre, E | 1 |
| Chalmers, JS; Cohen, PR; Cowen, PJ; Julier, DL; McCance, SL; Ware, CJ | 1 |
| Alvarez, E; Artigas, F; Celada, P; Martínez, E; Sarrias, MJ; Udina, C | 1 |
| Charney, DS; Delgado, PL; Heninger, GR; Price, LH | 2 |
| Berrettini, W; Brittain, H; Lawrence, D; Nurnberger, JI; Simmons-Alling, S | 1 |
| Ardisson, JL; Candito, M; Chambon, P; Darcourt, G; Iordache, A; Pringuey, D; Souêtre, E | 1 |
| Azorin, JM; Barré, A; Bovier, P; Chiaroni, P; Dufour, H; Jeanningros, R; Tatossian, A; Tissot, R; Widmer, J | 1 |
| Maurizi, CP | 1 |
| Meltzer, HL | 1 |
| Alvarez, E; Artigas, F; Gelpí, E; Martínez, E; Sarrias, MJ; Udina, C | 1 |
| Patterson, BD; Srisopark, MM | 1 |
| Sachs, GS | 1 |
| Cookson, JC | 1 |
| Bovier, P; Gaillard, JM; Tissot, R; Widmer, J | 1 |
| Chouinard, G | 1 |
| Chouinard, G; Steinberg, S; Steiner, W | 1 |
| Baxter, LR; Guzé, BH | 1 |
| Lerer, B | 1 |
| Goff, DC | 1 |
| Brooksbank, BW; Coppen, A; Peet, M | 1 |
| Bruce, A; Herrington, RN; Johnstone, EC | 1 |
| Ashcroft, GW; Blackburn, IM; Eccleston, D; Glen, AI; Hartley, W; Kinloch, NE; Lonergan, M; Murray, LG; Pullar, IA | 1 |
| Goodwin, FK; Post, RM | 1 |
| Huttunen, MO | 1 |
| Bunney, WE; Goodwin, FK; Gordon, EK; House, KM; Murphy, DL | 1 |
| Mandell, AJ; Spooner, CE | 1 |
| Allsopp, MN; Hullin, RP; Rees, JR | 1 |
| Bowers, MB | 1 |
| Matussek, N | 1 |
| Sarai, K | 1 |
| Alltop, LB; Lynn, CW; Prange, AJ; Stikeleather, RA; Wilson, IC | 1 |
| Gilmour, DG; Manowitz, P; Racevskis, J | 1 |
| Gayford, JJ; Parker, AL; Phillips, EM; Rowsell, AR | 1 |
| Henry, GM; Murphy, DL; Weingartner, H | 1 |
| Ashcroft, GW; Crawford, TB; Cundall, RL; Davidson, DL; Dobson, J; Dow, RC; Eccleston, D; Loose, RW; Pullar, IA | 1 |
| Frazer, A; Mendels, J; Pandey, GN | 1 |
| Bonkalo, A; Brown, GM; Cookson, BA; Lyall, WA; Quarrington, B; Stancer, HC | 1 |
| Brodie, HK; Bunney, WE; Goodwin, FK; Murphy, DL | 1 |
| Scharfetter, C | 1 |
| Cazzullo, CL; Mangoni, A; Mascherpa, G | 1 |
32 review(s) available for tryptophan and Bipolar Disorder
| Article | Year |
|---|---|
The association of kynurenine pathway metabolites with symptom severity and clinical features of bipolar disorder: An overview.
Topics: Affect; Bipolar Disorder; Humans; Kynurenine; Signal Transduction; Tryptophan | 2022 |
Linking nervous and immune systems in psychiatric illness: A meta-analysis of the kynurenine pathway.
Topics: Bipolar Disorder; Depressive Disorder, Major; Humans; Immune System; Kynurenic Acid; Kynurenine; Tryptophan | 2023 |
The kynurenine pathway in bipolar disorder: a meta-analysis on the peripheral blood levels of tryptophan and related metabolites.
Topics: Adult; Bipolar Disorder; Humans; Kynurenic Acid; Kynurenine; Observational Studies as Topic; Quinolinic Acid; Tryptophan | 2021 |
Tryptophan Catabolites in Bipolar Disorder: A Meta-Analysis.
Topics: Bipolar Disorder; Depression; Humans; Inflammation; Kynurenic Acid; Kynurenine; Tryptophan | 2021 |
Ketamine's effect on inflammation and kynurenine pathway in depression: A systematic review.
Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents; Bipolar Disorder; Cytokines; Depressive Disorder, Major; Humans; Inflammation; Ketamine; Kynurenine; Tryptophan | 2021 |
Meta-analysis of Cerebrospinal Fluid Cytokine and Tryptophan Catabolite Alterations in Psychiatric Patients: Comparisons Between Schizophrenia, Bipolar Disorder, and Depression.
Topics: Bipolar Disorder; Cytokines; Depressive Disorder, Major; Humans; Inflammation; Schizophrenia; Tryptophan | 2018 |
Metabolomics in patients with psychosis: A systematic review.
Topics: 3-Hydroxybutyric Acid; Aspartic Acid; Biomarkers; Bipolar Disorder; Creatine; Female; Glutamic Acid; Glutathione; Humans; Kynurenine; Lactic Acid; Linoleic Acid; Male; Metabolome; Metabolomics; Psychotic Disorders; Schizophrenia; Serine; Tryptophan | 2018 |
Novel nutritional treatment for manic and psychotic disorders: a review of tryptophan and tyrosine depletion studies and the potential of protein-based formulations using glycomacropeptide.
Topics: Bipolar Disorder; Brain; Caseins; Humans; Neuropsychological Tests; Nutritional Requirements; Peptide Fragments; Psychotic Disorders; Tryptophan; Tyrosine | 2013 |
Bipolar disorder: role of immune-inflammatory cytokines, oxidative and nitrosative stress and tryptophan catabolites.
Topics: Bipolar Disorder; Cytokines; Humans; Inflammation; Oxidation-Reduction; Oxidative Stress; Reactive Nitrogen Species; Tryptophan | 2015 |
Bipolar Disorder: The Role of the Kynurenine and Melatonergic Pathways.
Topics: Animals; Bipolar Disorder; Humans; Kynurenine; Melatonin; Signal Transduction; Tryptophan | 2016 |
Bipolar disorder and complementary medicine: current evidence, safety issues, and clinical considerations.
Topics: Acetylcysteine; Acupuncture Therapy; Amino Acids, Branched-Chain; Bipolar Disorder; Complementary Therapies; Dietary Supplements; Drug Therapy, Combination; Fatty Acids, Omega-3; Humans; Integrative Medicine; Magnesium; Micronutrients; Psychotropic Drugs; Tryptophan | 2011 |
Nutrient-based therapies for bipolar disorder: a systematic review.
Topics: Antidepressive Agents, Second-Generation; Bipolar Disorder; Choline; Chromium; Dietary Supplements; Fatty Acids, Omega-3; Folic Acid; Humans; Inositol; Lipotropic Agents; Magnesium; Trace Elements; Tryptophan; Vitamin B Complex | 2013 |
Acute tryptophan depletion. Part II: clinical effects and implications.
Topics: Alleles; Alzheimer Disease; Autistic Disorder; Bipolar Disorder; Cognitive Behavioral Therapy; Depressive Disorder, Major; Disruptive, Impulse Control, and Conduct Disorders; Feeding and Eating Disorders; Female; Humans; Hydroxyindoleacetic Acid; Monoamine Oxidase Inhibitors; Premenstrual Syndrome; Promoter Regions, Genetic; Schizophrenia; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Sleep Wake Disorders; Sleep, REM; Surveys and Questionnaires; Tryptophan | 2005 |
Lithium, membranes, and manic-depressive illness.
Topics: Adenylyl Cyclases; Animals; Biological Transport; Bipolar Disorder; Blood-Brain Barrier; Calcium; Cations; Chemical Phenomena; Chemistry; Choline; Epithelium; Erythrocyte Membrane; Erythrocytes; Humans; Intestinal Absorption; Kidney; Kinetics; Lithium; Magnesium; Membrane Potentials; Muscles; Neurons; Ouabain; Potassium; Salivary Glands; Sodium; Tryptophan | 1980 |
Rapid depletion of plasma tryptophan: a review of studies and experimental methodology.
Topics: Bipolar Disorder; Diet Therapy; Enzyme Inhibitors; Humans; Mental Disorders; Psychotropic Drugs; Tryptophan; Tryptophan Hydroxylase | 1997 |
Serotonin in mania and in the mechanism of action of mood stabilizers: a review of clinical studies.
Topics: Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Blood Platelets; Brain; Clinical Trials as Topic; Humans; Lithium Compounds; Neurotransmitter Agents; Serotonin; Tryptophan | 2000 |
The effects of tryptophan depletion on mood and psychiatric symptoms.
Topics: Anorexia Nervosa; Bipolar Disorder; Brain; Bulimia; Cognition Disorders; Depressive Disorder, Major; Humans; Mood Disorders; Obsessive-Compulsive Disorder; Recurrence; Serotonin; Severity of Illness Index; Substance-Related Disorders; Tryptophan | 2001 |
Neurochemical and neuropharmacological aspects of depression.
Topics: Addison Disease; Adrenal Cortex Hormones; Amphetamines; Animals; Antidepressive Agents, Tricyclic; Bipolar Disorder; Brain; Cushing Syndrome; Cyclic AMP; Depression; Electroconvulsive Therapy; Humans; Lithium; Methyltyrosines; Monoamine Oxidase Inhibitors; Neurotransmitter Agents; Reserpine; Tryptophan | 1975 |
Biochemistry of mental depression.
Topics: Age Factors; Bipolar Disorder; Blood Platelets; Brain; Catechol O-Methyltransferase; Depression; Dopamine; Female; Hormones; Humans; Male; Monoamine Oxidase; Neurotransmitter Agents; Norepinephrine; Serotonin; Sex Factors; Tryptophan | 1977 |
Biogenic amines and affective disorders. A critical analysis.
Topics: 5-Hydroxytryptophan; Affective Symptoms; Antidepressive Agents, Tricyclic; Biogenic Amines; Bipolar Disorder; Brain Chemistry; Clinical Trials as Topic; Depression; Electroconvulsive Therapy; Fenclonine; Fusaric Acid; Humans; Levodopa; Lithium; Methyldopa; Methyltyrosines; Methysergide; Monoamine Oxidase Inhibitors; Phenylketonurias; Reserpine; Tryptophan | 1976 |
The brain serotonergic system in the affective disorders.
Topics: 5-Hydroxytryptophan; Affective Symptoms; Animals; Bipolar Disorder; Brain; Brain Chemistry; Fenclonine; Humans; Receptors, Serotonin; Serotonin; Synaptic Transmission; Tryptophan | 1978 |
[Therapeutically resistant depressive states].
Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depersonalization; Depression; Drug Resistance; Electroconvulsive Therapy; Half-Life; Humans; Hypochondriasis; Levodopa; Middle Aged; Monoamine Oxidase Inhibitors; Sleep Deprivation; Syndrome; Thyrotropin; Tryptophan | 1979 |
The common pathophysiology of monaminergic psychoses: a new hypothesis.
Topics: 5-Hydroxytryptophan; Amino Acids; Biological Transport, Active; Bipolar Disorder; Blood-Brain Barrier; Brain; Catecholamines; Clomipramine; Dihydroxyphenylalanine; Dopamine; Electroconvulsive Therapy; Humans; Lithium; Lysergic Acid Diethylamide; Models, Biological; Monoamine Oxidase Inhibitors; Psychotic Disorders; Schizophrenia; Serotonin; Tranquilizing Agents; Tryptophan; Tyrosine | 1975 |
Adjuncts and alternatives to lithium therapy for bipolar affective disorder.
Topics: Anticonvulsants; Antidepressive Agents; Bipolar Disorder; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Lithium; Thyroid Hormones; Tryptophan | 1989 |
Drug treatment of bipolar depression and mania.
Topics: Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Bromocriptine; Carbamazepine; Cholinesterase Inhibitors; Clonidine; Depressive Disorder; Double-Blind Method; Drug Therapy, Combination; Humans; Lithium; Monoamine Oxidase Inhibitors; Phosphatidylcholines; Tryptophan; Valproic Acid; Verapamil | 1985 |
Clonazepam in acute and maintenance treatment of bipolar affective disorder.
Topics: Acute Disease; Adult; Bipolar Disorder; Clinical Trials as Topic; Clonazepam; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Haloperidol; Humans; Lithium; Male; Middle Aged; Tryptophan | 1987 |
Alternative therapies for bipolar disorder.
Topics: Ascorbic Acid; Bipolar Disorder; Bupropion; Carbamazepine; Choline; Clonazepam; Clonidine; Clorgyline; Demeclocycline; Fenfluramine; Humans; Methylene Blue; Phosphatidylcholines; Physostigmine; Propiophenones; Propranolol; Spironolactone; Thyroxine; Tryptophan; Valproic Acid | 1985 |
[The biochemistry of mental disorders].
Topics: Bipolar Disorder; Catecholamines; Humans; Indoles; Monoamine Oxidase Inhibitors; Receptors, Neurotransmitter; Schizophrenia; Tryptophan | 1970 |
Psychochemical research studies in man.
Topics: Animals; Behavior; Bipolar Disorder; Brain; Brain Chemistry; Depression; Dihydroxyphenylalanine; Hallucinogens; Hartnup Disease; Humans; Imipramine; Metabolism, Inborn Errors; Models, Neurological; Neurons; Neurotransmitter Agents; Norepinephrine; Phenylketonurias; Psychopharmacology; Sleep, REM; Tryptophan | 1968 |
[Biochemistry of depression].
Topics: Animals; Bipolar Disorder; Brain; Central Nervous System; Depression; Dihydroxyphenylalanine; Glycols; Humans; Hydroxyindoleacetic Acid; Norepinephrine; Parkinson Disease; Peripheral Nerves; Phenylacetates; Serotonin; Tryptophan; Tryptophan Hydroxylase | 1972 |
[Biochemical approach to manic-depressive disorders].
Topics: Amines; Amino Acids; Bipolar Disorder; Brain; Brain Chemistry; Catecholamines; Cell Membrane Permeability; Electrolytes; Humans; Serotonin; Stress, Physiological; Tryptophan | 1973 |
[Recent research in the field of affective psychoses, particularly depressions].
Topics: Adolescent; Adult; Age Factors; Bipolar Disorder; Catecholamines; Depression; Female; Humans; Lithium; Male; Middle Aged; Prognosis; Seasons; Serotonin; Sex Factors; Tryptophan | 1971 |
34 trial(s) available for tryptophan and Bipolar Disorder
| Article | Year |
|---|---|
Mood, prolactin and cortisol responses following intravenous L-tryptophan challenge: evidence for serotonergic vulnerability in first-degree relatives of bipolar patients.
Topics: Adult; Affect; Antidepressive Agents, Second-Generation; Bipolar Disorder; Female; Humans; Hydrocortisone; Injections, Intravenous; Male; Prolactin; Psychiatric Status Rating Scales; Tryptophan | 2002 |
Effects of acute tryptophan depletion on mood and cortisol release in first-degree relatives of type I and type II bipolar patients and healthy matched controls.
Topics: Adult; Affect; Bipolar Disorder; Cross-Over Studies; Double-Blind Method; Family; Female; Humans; Hydrocortisone; Linear Models; Male; Middle Aged; Statistics, Nonparametric; Tryptophan | 2002 |
Reversed diurnal variation in depression: associations with a differential antidepressant response, tryptophan: large neutral amino acid ratio and serotonin transporter polymorphisms.
Topics: Adult; Affect; Alleles; Amino Acids; Antidepressive Agents; Bipolar Disorder; Circadian Rhythm; Depressive Disorder, Major; Female; Fluoxetine; Gene Frequency; Genotype; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Nortriptyline; Polymorphism, Genetic; Prognosis; Promoter Regions, Genetic; Serotonin Plasma Membrane Transport Proteins; Treatment Outcome; Tryptophan | 2005 |
Rapid tryptophan depletion as a treatment for acute mania: a double-blind, pilot-controlled study.
Topics: Adult; Analysis of Variance; Bipolar Disorder; Diet, Reducing; Double-Blind Method; Female; Humans; Male; Pilot Projects; Psychiatric Status Rating Scales; Time Factors; Tryptophan | 2007 |
Diminished 5-HT functioning in CBCL pediatric bipolar disorder-profiled ADHD patients versus normal ADHD: susceptibility to rapid tryptophan depletion influences reaction time performance.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Child; Child Behavior Disorders; Cross-Over Studies; Double-Blind Method; Humans; Male; Reaction Time; Serotonin; Tryptophan | 2008 |
Lithium carbonate and L-tryptophan in the treatment of bipolar and schizoaffective disorders.
Topics: Adult; Bipolar Disorder; Clinical Trials as Topic; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Humans; Lithium; Lithium Carbonate; Male; Psychiatric Status Rating Scales; Psychotic Disorders; Tryptophan | 1983 |
Tryptophan depletion in stable lithium-treated patients with bipolar disorder in remission.
Topics: Adult; Bipolar Disorder; Diet; Humans; Lithium Carbonate; Male; Psychiatric Status Rating Scales; Serotonin; Tryptophan | 1995 |
Plasma tryptophan to large neutral amino acids ratio and therapeutic response to a selective serotonin uptake inhibitor.
Topics: Adult; Aged; Amino Acids; Bipolar Disorder; Depressive Disorder; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluvoxamine; Humans; Male; Middle Aged; Personality Inventory; Tryptophan | 1994 |
Effects of acute tryptophan depletion in lithium-remitted manic patients: a pilot study.
Topics: Adult; Antimanic Agents; Bipolar Disorder; Diet; Female; Humans; Lithium; Male; Middle Aged; Pilot Projects; Psychiatric Status Rating Scales; Serotonin; Tryptophan | 1997 |
Tryptophan depletion in recently manic patients treated with lithium.
Topics: Adult; Aged; Antimanic Agents; Bipolar Disorder; Double-Blind Method; Female; Humans; Lithium; Male; Middle Aged; Psychiatric Status Rating Scales; Tryptophan | 1998 |
The effect of acute tryptophan depletion and fenfluramine on quantitative EEG and mood in healthy male subjects.
Topics: Adolescent; Adult; Affect; Amino Acids; Bipolar Disorder; Double-Blind Method; Electroencephalography; Fenfluramine; Health Status; Humans; Male; Pilot Projects; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Single-Blind Method; Tryptophan | 1999 |
Effects of acute tryptophan depletion on mood and suicidal ideation in bipolar patients symptomatically stable on lithium.
Topics: Adult; Affect; Antimanic Agents; Bipolar Disorder; Cross-Over Studies; Double-Blind Method; Female; Humans; Lithium; Lithium Carbonate; Male; Middle Aged; Psychiatric Status Rating Scales; Psychometrics; Serotonin; Suicide; Tryptophan | 2000 |
Clinical and neurochemical effect of acute tryptophan depletion in unaffected relatives of patients with bipolar affective disorder.
Topics: Acute Disease; Adult; Antidepressive Agents, Tricyclic; Bipolar Disorder; Blood Platelets; Brain; Cross-Over Studies; Double-Blind Method; Female; Humans; Imipramine; Male; Serotonin; Synaptic Transmission; Tryptophan | 2001 |
Tryptophan depletion in lithium-stabilized patients with affective disorder.
Topics: Adrenocorticotropic Hormone; Adult; Affect; Aged; Amino Acids; Antimanic Agents; Bipolar Disorder; Double-Blind Method; Female; Humans; Hydrocortisone; Lithium; Male; Middle Aged; Mood Disorders; Prolactin; Serotonin; Tryptophan | 2001 |
Effects of acute tryptophan depletion on cognitive function in euthymic bipolar patients.
Topics: Adult; Analysis of Variance; Bipolar Disorder; Cognition; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Memory; Middle Aged; Neuropsychological Tests; Thymus Gland; Tryptophan | 2002 |
Cognition following acute tryptophan depletion: difference between first-degree relatives of bipolar disorder patients and matched healthy control volunteers.
Topics: Administration, Oral; Adult; Amino Acids; Bipolar Disorder; Cognition Disorders; Double-Blind Method; Female; Frontal Lobe; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Neuropsychological Tests; Risk; Serotonin; Tryptophan | 2002 |
Biogenic amines and affective disorders. A critical analysis.
Topics: 5-Hydroxytryptophan; Affective Symptoms; Antidepressive Agents, Tricyclic; Biogenic Amines; Bipolar Disorder; Brain Chemistry; Clinical Trials as Topic; Depression; Electroconvulsive Therapy; Fenclonine; Fusaric Acid; Humans; Levodopa; Lithium; Methyldopa; Methyltyrosines; Methysergide; Monoamine Oxidase Inhibitors; Phenylketonurias; Reserpine; Tryptophan | 1976 |
Tryptophan-nicotinamide, imipramine and their combination in depression. A controlled study.
Topics: Adult; Bipolar Disorder; Clinical Trials as Topic; Depression; Double-Blind Method; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Female; Humans; Imipramine; Kynurenine; Male; Middle Aged; Niacinamide; Psychiatric Status Rating Scales; Tryptophan | 1979 |
A controlled trial of L-tryptophan in mania.
Topics: Adult; Ascorbic Acid; Bipolar Disorder; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Drug Evaluation; Female; Humans; Placebos; Psychiatric Status Rating Scales; Pyridoxine; Tryptophan | 1978 |
Controlled studies of the acute antidepressant effects of lithium.
Topics: Adult; Aged; Bipolar Disorder; Clinical Trials as Topic; Depression; Double-Blind Method; Drug Combinations; Female; Humans; Imipramine; Lithium; Middle Aged; Random Allocation; Tryptophan | 1979 |
L-tryptophan in depression.
Topics: Adult; Antidepressive Agents, Tricyclic; Biological Transport, Active; Bipolar Disorder; Clinical Trials as Topic; Depression; Female; Humans; Lithium; Male; Middle Aged; Monoamine Oxidase Inhibitors; Phenelzine; Placebos; Psychiatric Status Rating Scales; Time Factors; Tranylcypromine; Tryptophan | 1976 |
Affective disorder: studies with amine precursors.
Topics: Adult; Antidepressive Agents; Biogenic Amines; Bipolar Disorder; Brain; Brain Chemistry; Clinical Trials as Topic; Depression; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Middle Aged; Models, Biological; Placebos; Remission, Spontaneous; Tryptophan | 1975 |
Amine precursors and depression.
Topics: Adult; Aged; Bipolar Disorder; Clinical Trials as Topic; Depression; Humans; Levodopa; Male; Middle Aged; Placebos; Psychiatric Status Rating Scales; Recurrence; Tryptophan | 1975 |
Blunted ACTH and cortisol response to afternoon tryptophan infusion in euthymic bipolar patients.
Topics: Adrenocorticotropic Hormone; Adult; Bipolar Disorder; Circadian Rhythm; Female; Growth Hormone; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Infusions, Intravenous; Male; Pituitary-Adrenal System; Prolactin; Tryptophan | 1990 |
Adjuncts and alternatives to lithium therapy for bipolar affective disorder.
Topics: Anticonvulsants; Antidepressive Agents; Bipolar Disorder; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Lithium; Thyroid Hormones; Tryptophan | 1989 |
Clonazepam in acute and maintenance treatment of bipolar affective disorder.
Topics: Acute Disease; Adult; Bipolar Disorder; Clinical Trials as Topic; Clonazepam; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Haloperidol; Humans; Lithium; Male; Middle Aged; Tryptophan | 1987 |
A controlled clinical trial of L-tryptophan in acute mania.
Topics: Acute Disease; Adolescent; Adult; Bipolar Disorder; Clinical Trials as Topic; Female; Humans; Kinetics; Kynurenine; Male; Middle Aged; Psychiatric Status Rating Scales; Tryptophan | 1985 |
Tryptophan concentration in the cerebrospinal fluid of depressive patients.
Topics: Adult; Aged; Biological Transport; Bipolar Disorder; Clinical Trials as Topic; Depression; Female; Humans; Male; Middle Aged; Tryptophan | 1972 |
Comparative trial of L-tryptophan and E.C.T. in severe depressive illness.
Topics: Administration, Oral; Adult; Aged; Bipolar Disorder; Drug Evaluation; Electroconvulsive Therapy; Evaluation Studies as Topic; Female; Follow-Up Studies; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Sex Factors; Time Factors; Tryptophan | 1974 |
Estimation of brain amine metabolism in affective illness: cerebrospinal fluid studies utilizing probenecid.
Topics: Bipolar Disorder; Brain; Depression; Dihydroxyphenylalanine; Fenclonine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methyltyrosines; Phenylacetates; Placebos; Probenecid; Stimulation, Chemical; Substance-Related Disorders; Tryptophan | 1974 |
The "switch process" in manic-depressive illness. II. Relationship to catecholamines, REM sleep, and drugs.
Topics: Affective Symptoms; Antidepressive Agents; Bipolar Disorder; Catecholamines; Catechols; Dihydroxyphenylalanine; Dopamine; Electroencephalography; Epinephrine; Glycols; Humans; Hydroxyindoleacetic Acid; Norepinephrine; Sleep; Sleep, REM; Tryptophan | 1972 |
L-tryptophan in mania. Contribution to a permissive hypothesis of affective disorders.
Topics: Adult; Affective Symptoms; Amines; Bipolar Disorder; Brain; Catecholamines; Chlorpromazine; Clinical Trials as Topic; Depression; Drug Evaluation; Female; Humans; Indoles; Male; Middle Aged; Placebos; Psychiatric Status Rating Scales; Remission, Spontaneous; Tryptophan | 1974 |
A longitudinal drug study and central amines.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Bipolar Disorder; Blood Pressure; Body Temperature; Body Weight; Brain; Clinical Trials as Topic; Drug Synergism; Electroencephalography; Factor Analysis, Statistical; Female; Humans; Menstruation; Norepinephrine; Placebos; Psychiatric Status Rating Scales; Pulse; Reserpine; Respiration; Serotonin; Sodium; Tranylcypromine; Tryptophan; Water-Electrolyte Balance | 1969 |
Studies of alpha-methyl-para-tyrosine, L-dopa, and L-tryptophan in depression and mania.
Topics: Bipolar Disorder; Catecholamines; Clinical Trials as Topic; Dihydroxyphenylalanine; Dopamine; Humans; Methyltyrosines; Placebos; Tryptophan | 1971 |
120 other study(ies) available for tryptophan and Bipolar Disorder
| Article | Year |
|---|---|
Selective association of cytokine levels and kynurenine/tryptophan ratio with alterations in white matter microstructure in bipolar but not in unipolar depression.
Topics: Biomarkers; Bipolar Disorder; Cytokines; Depressive Disorder, Major; Humans; Kynurenine; Tryptophan; White Matter | 2022 |
The Role of Kynurenines in Cognitive Dysfunction in Bipolar Disorder.
Topics: Bipolar Disorder; Cognitive Dysfunction; Humans; Inflammation; Kynurenic Acid; Kynurenine; Tryptophan | 2022 |
A mood state-specific interaction between kynurenine metabolism and inflammation is present in bipolar disorder.
Topics: Adult; Affect; Biomarkers; Bipolar Disorder; C-Reactive Protein; Depression; Female; Humans; Inflammation; Kynurenine; Male; Middle Aged; Symptom Assessment; Tryptophan | 2020 |
Grey and white matter structure associates with the activation of the tryptophan to kynurenine pathway in bipolar disorder.
Topics: Adult; Biomarkers; Bipolar Disorder; Brain; Female; Gray Matter; Humans; Kynurenine; Magnetic Resonance Imaging; Male; Middle Aged; Organ Size; Tryptophan; White Matter | 2019 |
The kynurenine pathway and bipolar disorder: intersection of the monoaminergic and glutamatergic systems and immune response.
Topics: Adolescent; Adult; Aged; Bipolar Disorder; Humans; Immunity; Kynurenic Acid; Kynurenine; Middle Aged; Tryptophan; Young Adult | 2021 |
Shotgun metagenomics reveals both taxonomic and tryptophan pathway differences of gut microbiota in bipolar disorder with current major depressive episode patients.
Topics: Bipolar Disorder; Cross-Sectional Studies; Depressive Disorder, Major; Gastrointestinal Microbiome; Humans; Metagenomics; Tryptophan | 2021 |
Alterations in plasma kynurenine pathway metabolites in children and adolescents with bipolar disorder and unaffected offspring of bipolar parents: A preliminary study.
Topics: Adolescent; Adult; Bipolar Disorder; Child; Humans; Kynurenic Acid; Kynurenine; Parents; Tryptophan | 2021 |
Central levels of tryptophan metabolites in subjects with bipolar disorder.
Topics: Bipolar Disorder; Chromatography, Liquid; Humans; Kynurenic Acid; Kynurenine; Tandem Mass Spectrometry; Tryptophan | 2021 |
The kynurenine pathway in schizophrenia and other mental disorders: Insight from meta-analyses on the peripheral blood levels of tryptophan and related metabolites.
Topics: Bipolar Disorder; Humans; Kynurenic Acid; Kynurenine; Schizophrenia; Tryptophan | 2021 |
Tryptophan breakdown and cognition in bipolar disorder.
Topics: Adult; Bipolar Disorder; Case-Control Studies; Cognition; Female; Humans; Kynurenic Acid; Kynurenine; Male; Middle Aged; Neuropsychological Tests; Sex Factors; Tryptophan | 2017 |
The role of tryptophan metabolism and food craving in the relationship between obesity and bipolar disorder.
Topics: Adult; Bipolar Disorder; Body Mass Index; Craving; Eating; Energy Metabolism; Female; Food; Humans; Kynurenine; Lipid Metabolism; Male; Middle Aged; Neopterin; Nitrites; Obesity; Sex Factors; Tryptophan; Waist-Hip Ratio | 2018 |
Total sleep time and kynurenine metabolism associated with mood symptom severity in bipolar disorder.
Topics: Adult; Affect; Biomarkers; Bipolar Disorder; Depression; Female; Humans; Inflammation; Kynurenine; Male; Middle Aged; Neopterin; Outcome Assessment, Health Care; Serotonin; Sleep; Sleep Initiation and Maintenance Disorders; Tryptophan | 2018 |
A Preclinical Study of Casein Glycomacropeptide as a Dietary Intervention for Acute Mania.
Topics: Acute Disease; Amino Acids, Branched-Chain; Animals; Behavior, Animal; Bipolar Disorder; Caseins; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Dopamine; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; Serotonin; Tryptophan; Tyrosine | 2018 |
A step ahead: Exploring the gut microbiota in inpatients with bipolar disorder during a depressive episode.
Topics: Biomarkers; Bipolar Disorder; Case-Control Studies; Cross-Sectional Studies; Depression; Depressive Disorder; Gastrointestinal Microbiome; Humans; Inflammation; Inpatients; Kynurenine; Male; Tryptophan | 2019 |
Tryptophan and Kynurenine Metabolites: Are They Related to Depression?
Topics: Adult; Bipolar Disorder; Case-Control Studies; Depressive Disorder, Major; Female; Humans; Hydroxyindoleacetic Acid; Kynurenine; Male; ortho-Aminobenzoates; Suicide, Attempted; Tryptophan; Xanthurenates | 2019 |
[Tryptophan Metabolites in Plasma of Patients with Depression].
Topics: Bipolar Disorder; Depressive Disorder; Humans; Kynurenine; Tryptophan | 2018 |
Antidepressant effect of repeated ketamine administration on kynurenine pathway metabolites in patients with unipolar and bipolar depression.
Topics: Administration, Intravenous; Adult; Antidepressive Agents; Bipolar Disorder; China; Chromatography, Liquid; Depression; Depressive Disorder; Female; Humans; Ketamine; Kynurenic Acid; Kynurenine; Male; Tandem Mass Spectrometry; Tryptophan | 2018 |
Metabolic dysfunctions in the kynurenine pathway, noradrenergic and purine metabolism in schizophrenia and bipolar disorders.
Topics: Adolescent; Adult; Bipolar Disorder; Female; Humans; Kynurenine; Male; Metabolic Networks and Pathways; Metabolomics; Middle Aged; Psychotic Disorders; Schizophrenia; Tryptophan; Tyrosine; Young Adult | 2020 |
Twin study shows association between monocyte chemoattractant protein-1 and kynurenic acid in cerebrospinal fluid.
Topics: Adult; Aged; Bipolar Disorder; Chemokine CCL2; Cohort Studies; Female; Humans; Kynurenic Acid; Male; Middle Aged; Quinolinic Acid; Schizophrenia; Sweden; Tryptophan | 2020 |
Editorial.
Topics: Animals; Antisocial Personality Disorder; Biological Psychiatry; Biomarkers; Bipolar Disorder; Cognition; Depression; Disease Models, Animal; Histocompatibility Antigens Class II; Humans; Mice; Tryptophan | 2019 |
Appropriate amino acid mixtures for tryptophan depletion and tyrosine/phenylalanine depletion and the safety of long-term amino acid depletion in humans.
Topics: Bipolar Disorder; Caseins; Humans; Peptide Fragments; Psychotic Disorders; Tryptophan; Tyrosine | 2013 |
Appropriate amino acid mixtures for tryptophan depletion and tyrosine/phenylalanine depletion and the safety of long-term amino acid depletion in humans: reply.
Topics: Bipolar Disorder; Caseins; Humans; Peptide Fragments; Psychotic Disorders; Tryptophan; Tyrosine | 2013 |
Tryptophan breakdown is increased in euthymic overweight individuals with bipolar disorder: a preliminary report.
Topics: Adult; Bipolar Disorder; Female; Humans; Kynurenine; Male; Middle Aged; Overweight; Tryptophan | 2014 |
Kynurenine pathway and white matter microstructure in bipolar disorder.
Topics: Adult; Bipolar Disorder; Diffusion Tensor Imaging; Female; Humans; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Magnetic Resonance Imaging; Male; Middle Aged; Serotonin; Signal Transduction; Tryptophan; White Matter; Young Adult | 2018 |
Kynurenic acid and psychotic symptoms and personality traits in twins with psychiatric morbidity.
Topics: Bipolar Disorder; Female; Humans; Interleukin-6; Interleukin-8; Kynurenic Acid; Male; Middle Aged; Personality; Psychotic Disorders; Quinolinic Acid; Schizophrenia; Schizophrenic Psychology; Tryptophan; Tumor Necrosis Factor-alpha; Twins | 2017 |
Increased breakdown of kynurenine towards its neurotoxic branch in bipolar disorder.
Topics: Adult; Bipolar Disorder; Brain; Case-Control Studies; Cognition; Depression; Female; Humans; Inflammation; Kynurenic Acid; Kynurenine; Male; Middle Aged; Multivariate Analysis; ortho-Aminobenzoates; Quinolinic Acid; Tryptophan | 2017 |
Dietary tryptophan depletion according to body weight - a new treatment option in acute mania?
Topics: Adolescent; Antimanic Agents; Bipolar Disorder; Body Weight; Child; Feeding Behavior; Humans; Tryptophan | 2009 |
Rapid tryptophan depletion as a treatment for acute mania: safety and mechanism of the therapeutic effect.
Topics: Animals; Bipolar Disorder; Diet, Reducing; Humans; Time Factors; Tryptophan | 2008 |
Aberrant amino acid transport in fibroblasts from patients with bipolar disorder.
Topics: Adult; Biological Transport, Active; Bipolar Disorder; Cells, Cultured; Female; Fibroblasts; Humans; Male; Skin; Tryptophan; Tyrosine | 2009 |
Tryptophan depletion in bipolar mania: reduction of metabolic imbalance by administration according to body weight?
Topics: Bipolar Disorder; Body Weight; Diet, Reducing; Humans; Metabolic Diseases; Tryptophan | 2009 |
Tryptophan for refractory bipolar spectrum disorder and sleep-phase delay.
Topics: Bipolar Disorder; Female; Humans; Middle Aged; Phototherapy; Psychotropic Drugs; Sleep Wake Disorders; Treatment Outcome; Tryptophan | 2010 |
Genetic polymorphisms (at codons 194 and 399) in the DNA repair gene XRCC1 and susceptibility to bipolar disorder.
Topics: Bipolar Disorder; Case-Control Studies; DNA-Binding Proteins; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Glutamine; Humans; Linkage Disequilibrium; Male; Polymorphism, Genetic; Tryptophan; X-ray Repair Cross Complementing Protein 1 | 2012 |
Membrane Na(+)-K+ ATPase mediated cascade in bipolar mood disorder, major depressive disorder, and schizophrenia--relationship to hemispheric dominance.
Topics: Adult; Bipolar Disorder; Depressive Disorder, Major; Digoxin; Dominance, Cerebral; Humans; Hydroxymethylglutaryl CoA Reductases; Magnesium; Sampling Studies; Schizophrenia; Sodium-Potassium-Exchanging ATPase; Tryptophan; Tyrosine | 2002 |
Pronounced cognitive deficits following an intravenous L-tryptophan challenge in first-degree relatives of bipolar patients compared to healthy controls.
Topics: Adult; Bipolar Disorder; Cognition Disorders; Cross-Over Studies; Double-Blind Method; Female; Humans; Infusions, Intravenous; Linear Models; Male; Memory Disorders; Psychomotor Performance; Statistics, Nonparametric; Tryptophan | 2003 |
L-tryptophan challenge and cognitive deficits in bipolar disorder: evidence for hyperserotonergic and hypodopaminergic mechanisms.
Topics: Bipolar Disorder; Cognition Disorders; Dopamine; Humans; Serotonin; Tryptophan | 2003 |
[Urinary excretion of 5-hydroxyindolacetic acid (5-HIAA) in 150 patients with depressive syndrome and maniacal agitation. (Its modifications by 5-hydroxy-tryptophan loading and therapy in the depressive states)].
Topics: Bipolar Disorder; Depression; Depressive Disorder; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Monoamine Oxidase Inhibitors; Tryptophan | 1963 |
Lower high-density lipoprotein cholesterol and increased omega-6 polyunsaturated fatty acids in first-degree relatives of bipolar patients.
Topics: Adult; Analysis of Variance; Bipolar Disorder; Cholesterol; Cholesterol, LDL; Control Groups; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Female; Genetic Markers; Genetic Predisposition to Disease; Humans; Hydrocortisone; Male; Mental Status Schedule; Middle Aged; Netherlands; Nuclear Family; Prolactin; Tryptophan | 2004 |
Bipolar mania and plasma amino acids: increased levels of glycine.
Topics: Adult; Aged; Bipolar Disorder; Case-Control Studies; Female; Glutamic Acid; Glycine; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Tryptophan | 2006 |
Tryptophan breakdown pathway in bipolar mania.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Brief Psychiatric Rating Scale; Female; Gyrus Cinguli; Humans; Kynurenic Acid; Kynurenine; Male; Schizophrenia; Severity of Illness Index; Tryptophan | 2007 |
Alterations in kynurenine precursor and product levels in schizophrenia and bipolar disorder.
Topics: 3-Hydroxyanthranilic Acid; Adult; Biomarkers; Bipolar Disorder; Brain; Chromatography, High Pressure Liquid; Female; Gyrus Cinguli; Humans; Kynurenine; Middle Aged; Niacinamide; Predictive Value of Tests; Schizophrenia; Signal Transduction; Suicide; Tryptophan; Tryptophan Oxygenase | 2008 |
Adrenal cortical activity changes in manic-depressive illness. Influence on intermediary metabolism of tryptophan.
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Bipolar Disorder; Carbon Isotopes; Female; Humans; Kynurenine; Middle Aged; Pituitary-Adrenal Function Tests; Statistics as Topic; Tryptophan; Tryptophan Oxygenase | 1967 |
[Current biochemical conceptions of mental diseases. II. Role of changes in the biogenic amine system in the pathogenesis of affective disorders].
Topics: 3-Methoxy-4-hydroxyphenylethanol; Affective Disorders, Psychotic; Antidepressive Agents, Tricyclic; Biogenic Amines; Bipolar Disorder; Brain; Catechol O-Methyltransferase; Cyclic AMP; Depression; Dopamine; Dopamine beta-Hydroxylase; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Kynurenine; Monoamine Oxidase Inhibitors; Norepinephrine; Receptors, Dopamine; Reserpine; Serotonin; Tryptophan | 1980 |
Acid metabolites and precursor amino acids of 5-hydroxytryptamine and dopamine in affective and other psychiatric disorders.
Topics: Adjustment Disorders; Adult; Aged; Amino Acids; Bipolar Disorder; Depressive Disorder; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Mental Disorders; Middle Aged; Probenecid; Protein Precursors; Psychomotor Agitation; Psychotic Disorders; Serotonin; Tryptophan; Tyrosine | 1983 |
Cerebrospinal fluid biochemical examinations: do they reflect clinical or biological differences?
Topics: Adult; Aged; Alcoholism; Bipolar Disorder; Calcium; Depressive Disorder; Dexamethasone; Female; Homovanillic Acid; Humans; Hydrocortisone; Hydroxyindoleacetic Acid; Middle Aged; Schizophrenia; Tryptophan | 1983 |
Some clinical and biochemical predictors of outcome in depression.
Topics: Adult; Aged; Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Middle Aged; Prognosis; Suicide; Time Factors; Tryptophan | 1984 |
CSF neurochemistry in depressed, manic, and schizophrenic patients compared with that of normal controls.
Topics: Adolescent; Adult; Age Factors; Aged; Bipolar Disorder; Calcium; Choline; Depressive Disorder; Female; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Middle Aged; Research Design; Schizophrenia; Tryptophan; Tyrosine | 1984 |
Tryptophan and tyrosine ratios to neutral amino acids in endogenous depression. Relation to antidepressant response to amitriptyline and lithium + L-tryptophan.
Topics: Amino Acids; Amitriptyline; Bipolar Disorder; Depressive Disorder; Drug Therapy, Combination; Female; Humans; Lithium; Male; Middle Aged; Tryptophan; Tyrosine | 1983 |
CSF AMP in primary affective disorder: effects of probenecid and tryptophan.
Topics: Bipolar Disorder; Cyclic AMP; Depression; Humans; Probenecid; Tryptophan | 1980 |
Relationship between plasma ratio of tryptophan to competing amino acids and the response to L-tryptophan treatment in endogenously depressed patients.
Topics: Adult; Aged; Amino Acids; Bipolar Disorder; Depressive Disorder; Female; Humans; Male; Middle Aged; Tryptophan | 1980 |
Tryptophan in the treatment of depression.
Topics: Allopurinol; Antidepressive Agents, Tricyclic; Ascorbic Acid; Bipolar Disorder; Depression; Electroconvulsive Therapy; Humans; Monoamine Oxidase Inhibitors; Niacinamide; Pyridoxine; Tryptophan | 1981 |
Case report of a toxic reaction from a combination of tryptophan and phenelzine.
Topics: Adult; Bipolar Disorder; Depressive Disorder; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Humans; Male; Movement Disorders; Phenelzine; Tryptophan | 1984 |
Diurnal variation of total plasma tryptophan in depressive patients.
Topics: Adult; Aged; Antidepressive Agents; Bipolar Disorder; Circadian Rhythm; Combined Modality Therapy; Depressive Disorder; Female; Humans; Male; Middle Aged; Sleep Deprivation; Tryptophan | 1984 |
Postsynaptic serotonergic activity in depressive patients: evaluation of the neuroendocrine strategy.
Topics: 5-Hydroxytryptophan; Adult; Bipolar Disorder; Blood Glucose; Depressive Disorder; Female; Growth Hormone; Humans; Hydrocortisone; Male; Middle Aged; Prolactin; Receptors, Serotonin; Serotonin; Synapses; Thyrotropin; Tryptophan | 1982 |
Myoclonus and ocular oscillations induced by L-tryptophan.
Topics: Adult; Bipolar Disorder; Desipramine; Drug Therapy, Combination; Eye Movements; Female; Humans; Myoclonus; Saccades; Tranylcypromine; Tryptophan | 1982 |
L-Tryptophan in the maintenance treatment of bipolar II manic-depressive illness.
Topics: Bipolar Disorder; Female; Humans; Imipramine; Lithium; Middle Aged; Tryptophan | 1982 |
Measurement of the plasmatic level of free and protein-bound tryptophan in mental pathology.
Topics: Bipolar Disorder; Humans; Reference Values; Schizophrenia; Schizophrenic Psychology; Serotonin; Tryptophan | 1980 |
[Analysis of plasma amino acids-tryptophan and tyrosine ratios to other large neutral amino acids in manic-depressive illness].
Topics: Adolescent; Adult; Aged; Amino Acids; Bipolar Disorder; Female; Humans; Male; Middle Aged; Serotonin; Tryptophan; Tyrosine | 1994 |
Predictive value of tryptophan/large neutral amino acids ratio to antidepressant response.
Topics: Adult; Aged; Amino Acids; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depressive Disorder; Female; Humans; Male; Middle Aged; Norepinephrine; Personality Inventory; Selective Serotonin Reuptake Inhibitors; Serotonin; Treatment Outcome; Tryptophan | 1996 |
No early effects of electroconvulsive therapy on tryptophan metabolism and disposition in endogenous depression.
Topics: Adult; Aged; Antidepressive Agents; Bipolar Disorder; Brain; Combined Modality Therapy; Depressive Disorder; Electroconvulsive Therapy; Female; Humans; Male; Middle Aged; Serotonin; Treatment Outcome; Tryptophan | 1997 |
Endogenous alkaloids in the brain of rats loaded with tyrosine/tryptophan & in the serum of patients of neurodegenerative & psychiatric disorders.
Topics: Alkaloids; Animals; Bipolar Disorder; Brain; Chromatography, High Pressure Liquid; Epilepsy; Female; Humans; Parkinson Disease; Rats; Rats, Sprague-Dawley; Tryptophan; Tyrosine | 1998 |
Tryptophan for treatment of rapid-cycling bipolar disorder comorbid with fibromyalgia.
Topics: Adult; Antimanic Agents; Bipolar Disorder; Female; Fibromyalgia; Humans; Periodicity; Tryptophan | 2001 |
Screening ABCG1, the human homologue of the Drosophila white gene, for polymorphisms and association with bipolar affective disorder.
Topics: 3' Untranslated Regions; 5' Flanking Region; Animals; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; Bipolar Disorder; DNA Primers; DNA, Complementary; Drosophila; Drosophila Proteins; Exons; Eye Proteins; Genetic Testing; Genotype; Humans; Insect Proteins; Introns; Linkage Disequilibrium; Microsatellite Repeats; Polymorphism, Single Nucleotide; Tryptophan | 2001 |
Acute tryptophan depletion attenuates auditory event related potentials in bipolar disorder: a preliminary study.
Topics: Adult; Bipolar Disorder; Electroencephalography; Evoked Potentials, Auditory; Female; Humans; Lithium; Male; Middle Aged; Tryptophan | 2002 |
Effect of lithium and other drugs on the amphetamine chlordiazeposice hyperactivity in mice.
Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Bipolar Disorder; Brain Chemistry; Chlordiazepoxide; Disease Models, Animal; Dopamine beta-Hydroxylase; Enzyme Inhibitors; Female; Fenclonine; Humans; Hyperkinesis; Lithium; Mice; Motor Activity; Norepinephrine; Serotonin; Tryptophan | 1975 |
Tryptophan-nicotinamide combination in the treatment of newly admitted depressed patients.
Topics: Adult; Bipolar Disorder; Depression; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Niacinamide; Tryptophan | 1978 |
Potentiation of lithium by tryptophan in a patient with bipolar illness.
Topics: Bipolar Disorder; Drug Synergism; Drug Therapy, Combination; Female; Humans; Lithium; Middle Aged; Niacinamide; Tryptophan | 1979 |
Free and total plasma tryptophan in endogenous depression.
Topics: Adult; Aged; Bipolar Disorder; Depressive Disorder; Humans; Lithium; Middle Aged; Psychiatric Status Rating Scales; Tryptophan | 1979 |
[Biochemistry of depression].
Topics: Adrenocorticotropic Hormone; Bipolar Disorder; Contraceptives, Oral; Cyclic AMP; Depression; Dopamine; Estrogens; Female; Humans; Hydrocortisone; Hydroxyindoleacetic Acid; Norepinephrine; Serotonin; Triiodothyronine; Tryptophan | 1976 |
Sleep and behavioral changes possibly reflecting central receptor hypersensitivity following catecholamine synthesis inhibition in man.
Topics: Behavior; Bipolar Disorder; Dopamine; Humans; Levodopa; Norepinephrine; Receptors, Neurotransmitter; Sleep; Substance Withdrawal Syndrome; Tryptophan; Tyrosine | 1977 |
Cyclic AMP in cerebrospinal fluid of manic and depressive patients.
Topics: Administration, Oral; Amitriptyline; Bipolar Disorder; Cyclic AMP; Depression; Humans; Imipramine; Lithium; Methadone; Methyltyrosines; Physical Exertion; Probenecid; Tryptophan | 1977 |
Blood-brain movements of tryptophan and tyrosine in manic-depressive illness and schizophrenia.
Topics: Adult; Bipolar Disorder; Blood-Brain Barrier; Brain; Dihydroxyphenylalanine; Humans; Middle Aged; Schizophrenia; Serotonin; Tryptophan; Tyrosine | 1979 |
Theoretical and therapeutic potential of indolamine precursors in affective disorders.
Topics: 5-Hydroxytryptophan; Amino Acids; Bipolar Disorder; Depression; Emotions; Female; Humans; Levodopa; Male; Phenylalanine; Serotonin; Sex Factors; Tryptophan; Tyrosine | 1977 |
[Psychopharmacology of tryptophan (author's transl)].
Topics: Animals; Bipolar Disorder; Depression; Humans; Mental Disorders; Parkinson Disease; Schizophrenia; Serotonin; Sleep; Tryptophan | 1977 |
Plasma neutral amino acids in mania and depression: variation during acute and prolonged treatment with L-tryptophan.
Topics: Amino Acids; Bipolar Disorder; Female; Humans; Isoleucine; Kynurenine; Leucine; Middle Aged; Tryptophan; Tyrosine; Valine | 1979 |
Depression: new evidence in support of biological differentiation.
Topics: Adult; Bipolar Disorder; Carbidopa; Depression; Female; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Tryptamines; Tryptophan | 1979 |
Asymmetry and mood, emergent properties of serotonin regulation.
Topics: Affect; Amphetamine; Animals; Bipolar Disorder; Brain; Calcium; Cocaine; Dominance, Cerebral; Humans; Hydroxyindoleacetic Acid; Kinetics; Lithium; Rats; Serotonin; Tryptophan; Tryptophan Hydroxylase | 1979 |
The effect of allopurinol on the kynurenine formation in humans following a tryptophan load.
Topics: Allopurinol; Bipolar Disorder; Humans; Kynurenine; Tryptophan | 1978 |
A study of plasma tryptophan and tyrosine in mania.
Topics: Adolescent; Adult; Aged; Bipolar Disorder; Diet; Female; Humans; Middle Aged; Protein Binding; Remission, Spontaneous; Tryptophan; Tyrosine | 1977 |
[The level and circadian rhythm of plasma tryptophan, tyrosine and cortisol in manic-depressive patients and its clinical significances (author's transl)].
Topics: Adolescent; Adult; Aged; Bipolar Disorder; Circadian Rhythm; Female; Humans; Hydrocortisone; Imipramine; In Vitro Techniques; Male; Middle Aged; Tryptophan; Tyrosine | 1977 |
Lithium: clinical effects and cerebrospinal fluid acid monoamine metabolites.
Topics: Adult; Affective Symptoms; Aged; Biogenic Amines; Bipolar Disorder; Depression; Electroencephalography; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Lithium; Male; Middle Aged; Probenecid; Psychiatric Status Rating Scales; Schizophrenia; Tryptophan | 1977 |
[Uptake of tryptophan and tyrosine in some cases of manic depressive psychosis and schizophrenia (author's transl)].
Topics: Bipolar Disorder; Brain; Humans; Protein Binding; Schizophrenia; Tryptophan; Tyrosine | 1978 |
Hormones, electrolytes, and cerebrospinal fluid proteins in manic-melancholic patients.
Topics: Adolescent; Adult; Aged; Antidepressive Agents, Tricyclic; Bipolar Disorder; Cerebrospinal Fluid Proteins; Electroconvulsive Therapy; Female; Humans; Lithium; Male; Middle Aged; Phosphates; Thyroxine; Tranquilizing Agents; Triiodothyronine; Tryptophan | 1978 |
Multicompartmental analysis of amino acids: II. Tryptophan in affective disorder.
Topics: Adult; Aged; Antidepressive Agents; Bipolar Disorder; Depression; Female; Humans; Kinetics; Lithium; Male; Middle Aged; Protein Binding; Sex Factors; Stress, Psychological; Tryptophan | 1978 |
Plasma amino acids as an index for subgroups in manic depressive psychosis: correlation to effect of tryptophan.
Topics: Amino Acids; Bipolar Disorder; Drug Resistance; Female; Humans; Kynurenine; Male; Serotonin; Tryptophan | 1976 |
Prostaglandin F in patients with primary affective disorder.
Topics: Adult; Aged; Bipolar Disorder; Depression; Female; Humans; Male; Middle Aged; Probenecid; Prostaglandins F; Tryptophan | 1977 |
Cerebral circulation and EEG alpha frequency in relation to daily fluctuations in psychotic behavior.
Topics: Adult; Alpha Rhythm; Bipolar Disorder; Circadian Rhythm; Female; Humans; Longitudinal Studies; Menstruation; Middle Aged; Periodicity; Phenelzine; Psychiatric Status Rating Scales; Psychotic Disorders; Remission, Spontaneous; Schizophrenia; Schizophrenia, Catatonic; Time Factors; Tryptophan | 1976 |
Sexual disinhibition with L-tryptophan.
Topics: Bipolar Disorder; Electroconvulsive Therapy; Female; Humans; Middle Aged; Sexual Behavior; Tryptophan | 1976 |
A neurobiological model for the symmetrical prophylactic action of lithium in bipolar affective disorder.
Topics: Animals; Bipolar Disorder; Brain; Cocaine; Corpus Striatum; Humans; Kinetics; Lithium; Male; Mesencephalon; Models, Biological; Morphine; Rats; Serotonin; Synaptosomes; Time Factors; Tryptophan; Tryptophan Hydroxylase | 1976 |
Total and free plasma tryptophan levels in patients with affective disorders: effects of a peripheral decarboxylase inhibitor.
Topics: Adolescent; Adult; Bipolar Disorder; Carbidopa; Depression; Female; Humans; Hydrazines; Male; Middle Aged; Tryptophan | 1976 |
[Hypothetical concept: the physiopathological entity of monoaminergic psychoses].
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Behavior, Animal; Bipolar Disorder; Blood-Brain Barrier; Catecholamines; Diet; Humans; Levodopa; Neurons; Rats; Schizophrenia; Serotonin; Sexual Behavior; Tryptophan; Tyrosine | 1975 |
Reduced central serotonergic activity in mania: implications for the relationship between depression and mania.
Topics: Bipolar Disorder; Brain; Depression; Disease Models, Animal; Humans; Hydroxyindoleacetic Acid; Hypnotics and Sedatives; Imipramine; Lithium; Methysergide; Monoamine Oxidase Inhibitors; Phenylalanine; Probenecid; Serotonin; Tryptophan | 1975 |
Multicompartmental analysis of amino acid. 1. Preliminary data on concentrations, fluxes, and flow constants of tryptophan in affective illness.
Topics: Antidepressive Agents, Tricyclic; Biological Transport; Bipolar Disorder; Depression; Depression, Chemical; Female; Humans; Lithium; Male; Remission, Spontaneous; Sex Factors; Tryptophan | 1975 |
Current research in the indoleamine hypothesis of affective disorders.
Topics: Affective Symptoms; Animals; Bipolar Disorder; Brain; Cocaine; Humans; Indoles; Lithium; Male; Morphine; Rats; Serotonin; Synaptosomes; Time Factors; Tryptophan; Tryptophan Hydroxylase | 1975 |
Plasma tryptophan concentration in depressive illness and mania.
Topics: Adult; Bipolar Disorder; Depression; Dietary Proteins; Humans; Middle Aged; Nitrazepam; Remission, Spontaneous; Tryptophan | 1976 |
Plasma ratios of tryptophan and tyrosine to other large neutral amino acids in manic-depressive patients.
Topics: Adolescent; Adult; Aged; Amino Acids; Amitriptyline; Antipsychotic Agents; Bipolar Disorder; Dibenzothiepins; Female; Humans; Lithium Carbonate; Male; Mianserin; Middle Aged; Tryptophan; Tyrosine | 1992 |
Plasma tryptophan levels and plasma tryptophan/neutral amino acids ratio in patients with mood disorder, patients with obsessive-compulsive disorder, and normal subjects.
Topics: Adolescent; Adult; Aged; Amino Acids; Bipolar Disorder; Blood-Brain Barrier; Depressive Disorder; Female; Humans; Male; Middle Aged; Obsessive-Compulsive Disorder; Serotonin; Tryptophan | 1992 |
Circadian variation in total plasma tryptophan. Antidepressant treatment: drugs and phase advance.
Topics: Adult; Aged; Bipolar Disorder; Chromatography, High Pressure Liquid; Circadian Rhythm; Female; Humans; Mianserin; Middle Aged; Tryptophan; Viloxazine | 1992 |
Lithium in tricyclic-resistant depression. Correlation of increased brain 5-HT function with clinical outcome.
Topics: Adult; Antidepressive Agents, Tricyclic; Bipolar Disorder; Brain; Depressive Disorder; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Lithium Carbonate; Male; Prolactin; Psychiatric Status Rating Scales; Receptors, Serotonin; Synaptic Transmission; Tryptophan | 1991 |
Plasma free 5HT and platelet 5HT in depression: case-control studies and the effect of antidepressant therapy.
Topics: Antidepressive Agents; Bipolar Disorder; Blood Platelets; Case-Control Studies; Depression; Female; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Lithium; Male; Monoamine Oxidase Inhibitors; Serotonin; Tryptophan | 1991 |
Serotonin function and depression: neuroendocrine and mood responses to intravenous L-tryptophan in depressed patients and healthy comparison subjects.
Topics: Adult; Affect; Bipolar Disorder; Depressive Disorder; Female; Growth Hormone; Humans; Infusions, Intravenous; Male; Middle Aged; Prolactin; Serotonin; Tryptophan | 1991 |
Diurnal variation in total plasma tryptophan in controls and in depression.
Topics: Adult; Bipolar Disorder; Circadian Rhythm; Depressive Disorder; Female; Humans; Male; Middle Aged; Reference Values; Tryptophan | 1990 |
A multivariate analysis of red blood cell membrane transports and plasma levels of L-tyrosine and L-tryptophan in depressed patients before treatment and after clinical improvement.
Topics: Adult; Bipolar Disorder; Depressive Disorder; Erythrocyte Membrane; Female; Follow-Up Studies; Hospitalization; Humans; Male; Multivariate Analysis; Phenylalanine; Psychiatric Status Rating Scales; Tryptophan; Tyrosine | 1990 |
The therapeutic potential for tryptophan and melatonin: possible roles in depression, sleep, Alzheimer's disease and abnormal aging.
Topics: Aging; Animals; Bipolar Disorder; Dementia; Depressive Disorder; Humans; Melatonin; Mental Disorders; Sleep Wake Disorders; Tryptophan | 1990 |
Lithium mechanisms in bipolar illness and altered intracellular calcium functions.
Topics: Adenylyl Cyclases; Bipolar Disorder; Calcium; Calcium-Transporting ATPases; Enzyme Activation; gamma-Aminobutyric Acid; Glycogen Synthase; Humans; Ion Channels; Lithium; Microtubules; Norepinephrine; Phosphoric Monoester Hydrolases; Synaptic Transmission; Tryptophan; Tyrosine 3-Monooxygenase | 1986 |
Increased plasma free serotonin but unchanged platelet serotonin in bipolar patients treated chronically with lithium.
Topics: Adult; Bipolar Disorder; Blood Platelets; Chromatography, High Pressure Liquid; Female; Humans; Hydroxyindoleacetic Acid; Lithium; Male; Middle Aged; Serotonin; Tryptophan | 1989 |
Severe anorexia and possible psychosis or hypomania after trazodone-tryptophan treatment of aggression.
Topics: Adult; Aggression; Anorexia Nervosa; Bipolar Disorder; Drug Therapy, Combination; Female; Humans; Psychoses, Substance-Induced; Trazodone; Tryptophan | 1989 |
Lithium treatment and serotoninergic function. Neuroendocrine and behavioral responses to intravenous tryptophan in affective disorder.
Topics: Adult; Affect; Bipolar Disorder; Depressive Disorder; Dexamethasone; Drug Interactions; Female; Humans; Hydrocortisone; Infusions, Intravenous; Lithium; Male; Middle Aged; Prolactin; Serotonin; Time Factors; Tryptophan | 1989 |
Evolution of red blood cell membrane transport and plasma level of L-tyrosine and L-tryptophan in depressed treated patients according to clinical improvement.
Topics: Adult; Aged; Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Desipramine; Erythrocyte Membrane; Female; Fluvoxamine; Humans; Imipramine; Male; Middle Aged; Oximes; Psychological Tests; Tryptophan; Tyrosine | 1988 |
Estrogen-progesterone combination: another mood stabilizer?
Topics: Bipolar Disorder; Drug Therapy, Combination; Estrogens; Female; Humans; Lithium; Middle Aged; Progesterone; Tryptophan | 1987 |
The serotonin syndrome: case responsive to propranolol.
Topics: Adult; Bipolar Disorder; Female; Humans; Propranolol; Serotonin; Syndrome; Tryptophan | 1986 |
Two cases of hypomania following the addition of L-tryptophan to a monoamine oxidase inhibitor.
Topics: Adult; Bipolar Disorder; Depressive Disorder; Drug Therapy, Combination; Female; Humans; Monoamine Oxidase Inhibitors; Phenelzine; Sleep Initiation and Maintenance Disorders; Tranylcypromine; Tryptophan | 1985 |
Changes on recovery in the concentrations of tryptophan and the biogenic amine metabolites in the cerebrospinal fluid of patients with affective illness.
Topics: Adult; Affective Symptoms; Antipsychotic Agents; Biogenic Amines; Bipolar Disorder; Butyrophenones; Depression; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Phenothiazines; Receptors, Drug; Serotonin; Tryptophan | 1973 |
Plasma concentrations of tryptophan and other amino acids in manic-depressive patients.
Topics: Alanine; Arginine; Aspartic Acid; Bipolar Disorder; Emotions; Glutamates; Glycine; Humans; Isoleucine; Leucine; Methionine; Psychology; Serine; Threonine; Tryptophan; Tyrosine | 1974 |
Fluorometric measurement of 5-hydroxyindoleacetic acid (5HIAA) and tryptophan in human CSF: effects of high doses of probenecid.
Topics: Administration, Oral; Adolescent; Adult; Bipolar Disorder; Brain Chemistry; Depression; Female; Fluorometry; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Probenecid; Schizophrenia; Tryptophan | 1974 |
Low plasma tryptophan levels in recently hospitalized schizophrenics.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Bipolar Disorder; Chronic Disease; Depression; Diet; Female; Hospitalization; Humans; Length of Stay; Male; Middle Aged; Phenylalanine; Racial Groups; Schizophrenia; Sex Factors; Tryptophan; Tyrosine | 1973 |
Whole blood 5 -hydroxytryptamine during treatment of endogenous depressive illness.
Topics: Adult; Aged; Amitriptyline; Bipolar Disorder; Electroconvulsive Therapy; Female; Humans; Male; Middle Aged; Phenelzine; Remission, Spontaneous; Serotonin; Tryptophan | 1973 |
Influence of affective states and psychoactive drugs on verbal learning and memory.
Topics: Bipolar Disorder; Carbonates; Depression; Dihydroxyphenylalanine; Humans; Imipramine; Lithium; Memory; Methyltyrosines; Serial Learning; Tryptophan; Verbal Learning; Word Association Tests | 1973 |
5-Hydroxytryptamine metabolism in affective illness: the effect of tryptophan administration.
Topics: Adult; Affective Symptoms; Age Factors; Aged; Bipolar Disorder; Depression; Female; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Tryptophan; Tryptophan Hydroxylase | 1973 |
Metabolism of tryptophan in depressive disease.
Topics: Adult; Bipolar Disorder; Depression; Humans; Hydroxyindoleacetic Acid; Kynurenine; Male; Metabolic Clearance Rate; Middle Aged; Personality Disorders; Pyridoxine; Tryptamines; Tryptophan | 1973 |
Tryptophan metabolism in affective psychoses.
Topics: Adult; Amitriptyline; Antidepressive Agents; Bipolar Disorder; Female; Humans; Hydroxyindoleacetic Acid; Imipramine; Male; Middle Aged; Tranylcypromine; Tryptophan; Xanthurenates | 1966 |