tryptophan and Autism

tryptophan has been researched along with Autism in 43 studies

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-199012 (27.91)18.7374
1990's7 (16.28)18.2507
2000's11 (25.58)29.6817
2010's10 (23.26)24.3611
2020's3 (6.98)2.80

Authors

AuthorsStudies
Betti, L; Carmassi, C; Carpita, B; Cremone, IM; Dell'Osso, L; Giannaccini, G; Massimetti, G; Nardi, B; Palego, L1
Cheng, B; Li, X; Sun, Q; Wang, S; Wei, X; Xiao, M1
Chen, W; Kong, Q; Li, X; Tian, P; Wang, B; Wang, G; Zhang, H; Zhao, J1
Wu, WL1
Agus, A; Planchais, J; Sokol, H1
Hagino, Y; Hall, FS; Ikeda, K; Inagaki, M; Kasai, S; Kashii, H; Kotajima-Murakami, H; Mizuguchi, M; Murphy, D; Nishito, Y; Sato, A; Sora, I; Takamatsu, Y; Tanaka, M; Uhl, GR1
Borre, Y; de Theije, CG; Garssen, J; Kas, MJ; Koelink, PJ; Korte, SM; Korte-Bouws, GA; Kraneveld, AD; Lopes da Silva, S; Olivier, B; Wu, J1
Brammer, M; Cleare, A; Craig, M; Daly, E; Deeley, Q; Ecker, C; Giampietro, V; Gillan, N; Gudbrandsen, M; Hallahan, B; Johnston, P; Lamar, M; Murphy, C; Murphy, DG; Page, L; Robertson, D; Rubia, K; Schmitz, N; Spain, D; Toal, F1
Cryan, JF; Dinan, TG1
Abramson, RK; Anderson, BM; Bartlett, J; Cuccaro, ML; Gilbert, JR; Haines, JL; Pericak-Vance, MA; Schnetz-Boutaud, NC; Wotawa, AM; Wright, HH1
Beretich, GR1
Bolliger, MF; Boucard, AA; Carter, AS; Ko, J; Maher, TA; Milunsky, JM; Newton, S; Powell, CM; Südhof, TC; Tager-Flusberg, H; Zhang, C; Zhao, G1
Anderson, GM; Kema, IP; Kemperman, RF; Minderaa, RB; Mulder, EJ; Oosterloo-Duinkerken, A1
Kałuzna-Czaplinska, J; Michalska, M; Rynkowski, J1
Clayton, TA1
Brammer, M; Cleare, A; Craig, M; Daly, EM; Deeley, Q; Ecker, C; Giampietro, V; Gillan, N; Hallahan, B; Johnston, P; Lamar, M; Murphy, C; Murphy, DG; Page, L; Spain, D; Surguladze, S; Toal, F1
READ, JH; SUTTON, HE1
Kurup, PA; Kurup, RK1
Sanders-Bush, E; Sodhi, MS1
Chugani, DC1
Bell, CJ; Hood, SD; Nutt, DJ1
Carroll, RC; Connors, SL; Lozzio, CB; Matteson, KJ; Sega, GA; Zimmerman, AW1
Anderson, GM; Janusonis, S; Rakic, P; Shifrovich, I1
Hoshino, Y; Kaneko, M; Kumashiro, H; Ono, Y; Tachibana, R; Watanabe, M; Yamamoto, T1
Debray Ritzen, P; Douay, O; Kamoun, P1
Celli, M; D'Eufemia, P; Finocchiaro, R; Giardini, O; Monteleone, D; Viozzi, L1
Cohen, DJ; Goodman, WK; McDougle, CJ; Naylor, ST; Price, LH; Volkmar, FR1
Aghajanian, GK; Cohen, DJ; Heninger, GR; McDougle, CJ; Naylor, ST; Price, LH1
Doan, RJ1
Croonenberghs, J; Deboutte, D; Delmeire, L; Lin, AH; Maes, M; Meskal, A; Neels, H; Pison, G; Scharpe, S; Van der Planken, M; Verkerk, R1
Asano, E; Behen, M; Chakraborty, PK; Chugani, DC; Chugani, HT; Janisse, J; Mangner, TJ; Muzik, O; Rothermel, R1
Honda, K; Hoshino, Y; Kaneko, M; Kumashiro, H; Numata, Y; Tachibana, R; Watanabe, M; Yashima, Y1
Freedman, DX; Hanley, HG; Stahl, SM1
Ritvo, ER1
Guthrie, RD; Wyatt, RJ1
Anderson, GM; Cook, EH; Fletcher, KE; Freedman, DX; Heninger, GR; Leventhal, BL1
Anderson, GM1
Comings, BG; Comings, DE1
Akkerhuis, GW; Anderson, GM; Cohen, DJ; Minderaa, RB; Volkmar, FR1
Hayashi, T; Nakane, A; Naruse, H; Takesada, M; Yamazaki, K1
Akkerhuis, GW; Anderson, GM; Cohen, DJ; Harcherick, D; Minderaa, RB; Volkmar, FR1
Anderson, GM; Cohen, DJ; Freedman, DX; Hansen, CR; Hoder, EL; McPhedran, P; Minderaa, RB; Volkmar, FR; Young, JG1
Hoshino, Y; Kaneko, M; Kumashiro, H; Yamamoto, T1

Reviews

7 review(s) available for tryptophan and Autism

ArticleYear
Gut Microbiota Regulation of Tryptophan Metabolism in Health and Disease.
    Cell host & microbe, 2018, 06-13, Volume: 23, Issue:6

    Topics: Autistic Disorder; Colitis; Communicable Diseases; Crohn Disease; Gastrointestinal Microbiome; Gastrointestinal Tract; Humans; Indoles; Inflammatory Bowel Diseases; Kynurenine; Metabolic Syndrome; Obesity; Serotonin; Short Bowel Syndrome; Tryptophan

2018
The Microbiome-Gut-Brain Axis in Health and Disease.
    Gastroenterology clinics of North America, 2017, Volume: 46, Issue:1

    Topics: Animals; Autistic Disorder; Brain; Cytokines; Depression; Fatty Acids, Volatile; gamma-Aminobutyric Acid; Gastrointestinal Microbiome; Gastrointestinal Tract; Humans; Irritable Bowel Syndrome; Parkinson Disease; Prebiotics; Probiotics; Tryptophan; Vagus Nerve

2017
Serotonin and brain development.
    International review of neurobiology, 2004, Volume: 59

    Topics: Animals; Anxiety; Autistic Disorder; Brain; Brain Chemistry; Down Syndrome; Humans; Learning; Models, Animal; Mood Disorders; Neuronal Plasticity; Receptors, Serotonin; Schizophrenia; Serotonin; Stress, Physiological; Synapses; Tryptophan

2004
Serotonin in autism and pediatric epilepsies.
    Mental retardation and developmental disabilities research reviews, 2004, Volume: 10, Issue:2

    Topics: Animals; Autistic Disorder; Brain; Child; Electroencephalography; Epilepsy; Humans; Kynurenine; Magnetic Resonance Imaging; Mice; Positron-Emission Tomography; Serotonin; Tryptophan

2004
Acute tryptophan depletion. Part II: clinical effects and implications.
    The Australian and New Zealand journal of psychiatry, 2005, Volume: 39, Issue:7

    Topics: Alleles; Alzheimer Disease; Autistic Disorder; Bipolar Disorder; Cognitive Behavioral Therapy; Depressive Disorder, Major; Disruptive, Impulse Control, and Conduct Disorders; Feeding and Eating Disorders; Female; Humans; Hydroxyindoleacetic Acid; Monoamine Oxidase Inhibitors; Premenstrual Syndrome; Promoter Regions, Genetic; Schizophrenia; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Sleep Wake Disorders; Sleep, REM; Surveys and Questionnaires; Tryptophan

2005
Biochemistry and schizophrenia III. A review of childhood psychosis.
    Schizophrenia bulletin, 1975,Spring, Issue:12

    Topics: Autistic Disorder; Blood Platelets; Brain; Bufotenin; Child; Child, Preschool; Creatine Kinase; Dimethoxyphenylethylamine; Endocrine System Diseases; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Nicotinic Acids; Schizophrenia, Childhood; Serotonin; Sialic Acids; Tryptophan

1975
Signal-to-noise optimization of HPLC-fluorometric systems and their application to the analysis of indoles.
    Advances in experimental medicine and biology, 1991, Volume: 294

    Topics: Animals; Autistic Disorder; Chromatography, High Pressure Liquid; Fluorometry; Humans; Indoles; Rats; Tryptophan

1991

Trials

4 trial(s) available for tryptophan and Autism

ArticleYear
Serotonin and the neural processing of facial emotions in adults with autism: an fMRI study using acute tryptophan depletion.
    Archives of general psychiatry, 2012, Volume: 69, Issue:10

    Topics: Adolescent; Adult; Autistic Disorder; Brain; Cross-Over Studies; Double-Blind Method; Emotions; Facial Expression; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Serotonin; Tryptophan; Young Adult

2012
Acute tryptophan depletion in autistic disorder: a controlled case study.
    Biological psychiatry, 1993, Apr-01, Volume: 33, Issue:7

    Topics: Adult; Amino Acids; Autistic Disorder; Brain; Female; Humans; Serotonin; Social Behavior; Tryptophan

1993
Effects of tryptophan depletion in drug-free adults with autistic disorder.
    Archives of general psychiatry, 1996, Volume: 53, Issue:11

    Topics: Adult; Amino Acids, Essential; Autistic Disorder; Child; Double-Blind Method; Female; Humans; Male; Placebos; Psychiatric Status Rating Scales; Serotonin; Severity of Illness Index; Tryptophan

1996
[Metabolic changes in aromatic amino acids and monoamines in infantile autism and development of new treatment related to the finding].
    No to hattatsu = Brain and development, 1989, Volume: 21, Issue:2

    Topics: 5-Hydroxytryptophan; Amino Acids; Autistic Disorder; Biogenic Monoamines; Biopterins; Carbon Isotopes; Child; Child, Preschool; Clinical Trials as Topic; Deuterium; Double-Blind Method; Humans; Levodopa; Phenylalanine; Tryptophan

1989

Other Studies

32 other study(ies) available for tryptophan and Autism

ArticleYear
Kynurenine pathway and autism spectrum phenotypes: an investigation among adults with autism spectrum disorder and their first-degree relatives.
    CNS spectrums, 2023, Volume: 28, Issue:3

    Topics: Autism Spectrum Disorder; Autistic Disorder; Humans; Kynurenic Acid; Kynurenine; Phenotype; Tryptophan

2023
Vitamin A deficiency from maternal gestation may contribute to autistic-like behaviors and gastrointestinal dysfunction in rats through the disrupted purine and tryptophan metabolism.
    Behavioural brain research, 2023, 08-24, Volume: 452

    Topics: Animals; Autism Spectrum Disorder; Autistic Disorder; Female; Gastrointestinal Diseases; Pregnancy; Purines; Rats; Tryptophan; Vitamin A Deficiency

2023
Daily intake of Lactobacillus alleviates autistic-like behaviors by ameliorating the 5-hydroxytryptamine metabolic disorder in VPA-treated rats during weaning and sexual maturation.
    Food & function, 2021, Mar-21, Volume: 12, Issue:6

    Topics: Animals; Autistic Disorder; Behavior, Animal; Butyric Acid; Disease Models, Animal; Fatty Acids, Volatile; Gastrointestinal Microbiome; Lactobacillus; Probiotics; Rats; Serotonin; Sexual Maturation; Tryptophan; Valproic Acid; Weaning

2021
Association Among Gut Microbes, Intestinal Physiology, and Autism.
    EBioMedicine, 2017, Volume: 25

    Topics: Animals; Autistic Disorder; Bile Acids and Salts; Intestines; Mice; Microbiota; Tryptophan

2017
Brain hyperserotonemia causes autism-relevant social deficits in mice.
    Molecular autism, 2018, Volume: 9

    Topics: Animals; Autistic Disorder; Brain; Female; Male; Mice; Mice, Inbred C57BL; Serotonin; Serotonin Plasma Membrane Transport Proteins; Social Behavior; Tryptophan

2018
Autistic-like behavioural and neurochemical changes in a mouse model of food allergy.
    Behavioural brain research, 2014, Mar-15, Volume: 261

    Topics: Age Factors; Animals; Autistic Disorder; Biogenic Monoamines; Brain; Chromatography, High Pressure Liquid; Disease Models, Animal; Food Hypersensitivity; Grooming; Homovanillic Acid; Interpersonal Relations; Male; Maze Learning; Mice; Mice, Inbred C3H; Milk; Proto-Oncogene Proteins c-fos; Statistics, Nonparametric; Tryptophan

2014
Response inhibition and serotonin in autism: a functional MRI study using acute tryptophan depletion.
    Brain : a journal of neurology, 2014, Volume: 137, Issue:Pt 9

    Topics: Adolescent; Adult; Autistic Disorder; Brain; Cross-Over Studies; Double-Blind Method; Female; Humans; Magnetic Resonance Imaging; Male; Neural Inhibition; Photic Stimulation; Reaction Time; Serotonin; Tryptophan; Young Adult

2014
Examination of association of genes in the serotonin system to autism.
    Neurogenetics, 2009, Volume: 10, Issue:3

    Topics: Adolescent; Autistic Disorder; Child; Child, Preschool; Genetic Predisposition to Disease; Humans; Linkage Disequilibrium; Molecular Sequence Data; Molecular Structure; Polymorphism, Single Nucleotide; Serotonin; Tryptophan; Young Adult

2009
Reversal of autistic symptoms by removal of low-relative tryptophan foods: case report.
    Medical hypotheses, 2009, Volume: 73, Issue:5

    Topics: Autistic Disorder; Child, Preschool; Female; Humans; Tryptophan

2009
A neuroligin-4 missense mutation associated with autism impairs neuroligin-4 folding and endoplasmic reticulum export.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, Sep-02, Volume: 29, Issue:35

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Autistic Disorder; Carrier Proteins; Cell Adhesion Molecules, Neuronal; Cell Line; Child, Preschool; Chlorocebus aethiops; COS Cells; Endoplasmic Reticulum; Female; Humans; Male; Membrane Proteins; Mice; Molecular Sequence Data; Mutation, Missense; Protein Folding; Protein Transport; Tryptophan

2009
Urinary excretion of 5-hydroxyindoleacetic acid, serotonin and 6-sulphatoxymelatonin in normoserotonemic and hyperserotonemic autistic individuals.
    Neuropsychobiology, 2010, Volume: 61, Issue:1

    Topics: Adolescent; Age Factors; Autistic Disorder; Creatinine; Humans; Hydroxyindoleacetic Acid; Male; Melatonin; Serotonin; Tryptophan

2010
Determination of tryptophan in urine of autistic and healthy children by gas chromatography/mass spectrometry.
    Medical science monitor : international medical journal of experimental and clinical research, 2010, Volume: 16, Issue:10

    Topics: Autistic Disorder; Calibration; Case-Control Studies; Child; Female; Gas Chromatography-Mass Spectrometry; Humans; Limit of Detection; Male; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Serotonin; Time Factors; Tryptophan

2010
Metabolic differences underlying two distinct rat urinary phenotypes, a suggested role for gut microbial metabolism of phenylalanine and a possible connection to autism.
    FEBS letters, 2012, Apr-05, Volume: 586, Issue:7

    Topics: Animals; Autistic Disorder; Bacterial Proteins; Biomarkers; Chlorogenic Acid; Clostridium; Disease Models, Animal; Fungal Proteins; Glycine; Hippurates; Humans; Intestines; Phenylalanine; Phenylalanine Ammonia-Lyase; Rats; Stereoisomerism; Systems Biology; Tryptophan; Tyrosine; Yeasts

2012
Abnormal amino acid metabolism in a case suggesting autism.
    A.M.A. journal of diseases of children, 1958, Volume: 96, Issue:1

    Topics: Autistic Disorder; Behavior; Biochemical Phenomena; Humans; Tryptophan

1958
A hypothalamic digoxin-mediated model for autism.
    The International journal of neuroscience, 2003, Volume: 113, Issue:11

    Topics: Adolescent; Autistic Disorder; Child; Digoxin; Dolichols; Female; Humans; Hypothalamus; Magnesium; Male; Sodium-Potassium-Exchanging ATPase; Tryptophan; Tyrosine; Ubiquinone

2003
Plasma serotonin in autism.
    Pediatric neurology, 2006, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Autistic Disorder; Case-Control Studies; Child; Child, Preschool; Fathers; Female; Humans; Male; Middle Aged; Mothers; Pilot Projects; Serotonin; Siblings; Tryptophan

2006
Ontogeny of brain and blood serotonin levels in 5-HT receptor knockout mice: potential relevance to the neurobiology of autism.
    Journal of neurochemistry, 2006, Volume: 99, Issue:3

    Topics: Animals; Autistic Disorder; Blood Platelets; Brain; Brain Chemistry; Central Nervous System; Chromatography, High Pressure Liquid; Female; Genotype; Hydroxyindoleacetic Acid; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peripheral Nervous System; Receptor, Serotonin, 5-HT1A; Reverse Transcriptase Polymerase Chain Reaction; Serotonin; Tryptophan

2006
Blood serotonin and free tryptophan concentration in autistic children.
    Neuropsychobiology, 1984, Volume: 11, Issue:1

    Topics: Autistic Disorder; Brain; Child; Child, Preschool; Female; Humans; Hydroxyindoleacetic Acid; Male; Psychiatric Status Rating Scales; Serotonin; Tryptophan

1984
[Blood serotonin and tryptophan in autism].
    Annales de biologie clinique, 1980, Volume: 38, Issue:4

    Topics: Adolescent; Autistic Disorder; Child; Humans; Serotonin; Tryptophan

1980
Low serum tryptophan to large neutral amino acids ratio in idiopathic infantile autism.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1995, Volume: 49, Issue:6

    Topics: Adolescent; Amino Acids; Autistic Disorder; Central Nervous System; Child; Female; Humans; Male; Serotonin; Tryptophan

1995
Risperidone for insomnia in PDDs.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1998, Volume: 43, Issue:10

    Topics: Antipsychotic Agents; Autistic Disorder; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Hypnotics and Sedatives; Risperidone; Sleep Initiation and Maintenance Disorders; Tryptophan

1998
Peripheral markers of serotonergic and noradrenergic function in post-pubertal, caucasian males with autistic disorder.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2000, Volume: 22, Issue:3

    Topics: Adolescent; Autistic Disorder; Belgium; Biomarkers; Child; Dopamine; Epinephrine; Humans; Hydroxyindoleacetic Acid; Intelligence; Male; Netherlands; Norepinephrine; Paroxetine; Puberty; Serotonin; Tryptophan; Tyrosine; White People; Yohimbine

2000
Autism in tuberous sclerosis complex is related to both cortical and subcortical dysfunction.
    Neurology, 2001, Oct-09, Volume: 57, Issue:7

    Topics: Adolescent; Autistic Disorder; Carbon Radioisotopes; Cerebellar Nuclei; Cerebral Cortex; Child; Child, Preschool; Female; Fluorodeoxyglucose F18; Glucose; Humans; Infant; Male; Radiopharmaceuticals; Spasms, Infantile; Tomography, Emission-Computed; Tryptophan; Tuberous Sclerosis

2001
Serum serotonin, free tryptophan and plasma cyclic AMP levels in autistic children -with special reference to their relation to hyperkinesia.
    Fukushima journal of medical science, 1979, Volume: 26, Issue:3-4

    Topics: Adult; Autistic Disorder; Child; Child, Preschool; Cyclic AMP; Female; Humans; Hyperkinesis; Male; Serotonin; Tryptophan

1979
Hyperserotonemia and amine metabolites in autistic and retarded children.
    Archives of general psychiatry, 1977, Volume: 34, Issue:5

    Topics: Adolescent; Adult; Age Factors; Autistic Disorder; Child; Child, Institutionalized; Child, Preschool; Humans; Hydroxyindoleacetic Acid; Intellectual Disability; Intelligence; Motor Activity; Reserpine; Serotonin; Tryptamines; Tryptophan; Vanilmandelic Acid

1977
Biochemical studies of children with the syndromes of autism, childhood schizophrenia and related developmental disabilities: a review.
    Journal of child psychology and psychiatry, and allied disciplines, 1977, Volume: 18, Issue:4

    Topics: Autistic Disorder; Blood Platelets; Brain; Bufotenin; Child; Dopamine beta-Hydroxylase; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Intellectual Disability; Monoamine Oxidase; Schizophrenia, Childhood; Serotonin; Tryptophan

1977
Tryptophan loading in hyperserotonemic and normoserotonemic adults.
    Biological psychiatry, 1992, Mar-01, Volume: 31, Issue:5

    Topics: Administration, Oral; Adult; Arousal; Autistic Disorder; Blood Platelets; Dose-Response Relationship, Drug; Humans; Infusions, Intravenous; Male; Serotonin; Tryptophan

1992
Clinical and genetic relationships between autism-pervasive developmental disorder and Tourette syndrome: a study of 19 cases.
    American journal of medical genetics, 1991, May-01, Volume: 39, Issue:2

    Topics: Adolescent; Adult; Autistic Disorder; Child; Child Development Disorders, Pervasive; Child, Preschool; Female; Genes, Dominant; Genes, Recessive; Humans; Male; Pedigree; Serotonin; Tourette Syndrome; Tryptophan

1991
Urinary 5-hydroxyindoleacetic acid and whole blood serotonin and tryptophan in autistic and normal subjects.
    Biological psychiatry, 1987, Volume: 22, Issue:8

    Topics: Adolescent; Adult; Autistic Disorder; Female; Humans; Hydroxyindoleacetic Acid; Male; Serotonin; Tryptophan

1987
Whole blood serotonin and tryptophan in autism: temporal stability and the effects of medication.
    Journal of autism and developmental disorders, 1989, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Anticonvulsants; Autistic Disorder; Female; Haloperidol; Humans; Male; Phenothiazines; Platelet Count; Serotonin; Time Factors; Tryptophan

1989
Whole blood serotonin in autistic and normal subjects.
    Journal of child psychology and psychiatry, and allied disciplines, 1987, Volume: 28, Issue:6

    Topics: Adolescent; Adult; Anticonvulsants; Autistic Disorder; Blood Platelets; Child; Child, Preschool; Chromatography, High Pressure Liquid; Female; Haloperidol; Humans; Infant; Male; Platelet Count; Serotonin; Sex Factors; Thioridazine; Tryptophan

1987
Plasma free tryptophan concentration in autistic children.
    Brain & development, 1986, Volume: 8, Issue:4

    Topics: Adolescent; Adult; Autistic Disorder; Brain; Child; Child, Preschool; Female; Humans; Male; Serotonin; Tryptophan

1986