tryptophan and Attention Deficit Disorder with Hyperactivity

tryptophan has been researched along with Attention Deficit Disorder with Hyperactivity in 43 studies

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-19908 (18.60)18.7374
1990's3 (6.98)18.2507
2000's7 (16.28)29.6817
2010's19 (44.19)24.3611
2020's6 (13.95)2.80

Authors

AuthorsStudies
Dinu, LM; Dommett, EJ; Phattharakulnij, N1
Anand, NS; Hong, X; Pearson, C; Raghavan, R; Wang, G; Wang, X; Xie, H; Zuckerman, B1
Yamamoto, T1
Baker, NS; Dinu, LM; Dommett, EJ; Georgescu, AL; Overton, PG; Singh, SN1
Abuşoğlu, S; Bilgiç, A; Sağlam, E; Sivrikaya, A; Ünlü, A1
Blanca-Jover, E; Cantarero-Malagón, AM; Checa-Ros, A; Cubero-Millán, I; Fernández-López, L; Jerez-Calero, A; Machado-Casas, I; Molina-Carballo, A; Muñoz-Hoyos, A; Uberos, J1
Brummer, RJM; Sandgren, AM1
Biskup, CS; Dahmen, B; Landgraf, M; Poustka, F; Stadler, C; Wöckel, L; Zepf, FD1
Abdel-Hamid, M; Biskup, CS; Grabemann, M; Kis, B; Mette, C; Uekermann, J; Wiltfang, J; Zepf, FD; Zimmermann, M1
Abdel-Hamid, M; Grabemann, M; Heinrich, V; Kis, B; Mette, C; Uekermann, J; Wiltfang, J; Zepf, FD; Zimmermann, M1
Young, SN1
Abdel-Hamid, M; Biskup, CS; Bubenzer, S; Dahmen, B; Eisert, A; Gaber, TJ; Grabemann, M; Heinrich, V; Helmbold, K; Kis, B; Kötting, WF; Kuhn, CM; Landgraf, M; Mette, C; Poustka, F; Sánchez, CL; Stadler, C; Uekermann, J; Wiltfang, J; Wöckel, L; Zepf, FD; Zimmermann, M1
Biskup, CS; Bubenzer, S; Eisert, A; Gaber, TJ; Helmbold, K; Kötting, WF; von Polier, GG; Zepf, FD1
Dolina, S; Malitsky, S; Margalit, D; Rabinkov, A1
Banerjee, E; Nandagopal, K1
Bergwerff, CE; Blom, HJ; Luman, M; Oosterlaan, J1
Baurmann, D; Biskup, CS; Bubenzer-Busch, S; Fink, GR; Gaber, TJ; Helmbold, K; Klasen, M; Königschulte, W; Zepf, FD1
Holtmann, M; Poustka, F; Stadler, C; Wöckel, L; Zepf, FD1
Holtmann, M; Magnus, S; Poustka, F; Stadler, C; Wöckel, L; Zepf, FD1
Baurmann, D; Bubenzer, S; Gaber, TJ; Herpertz-Dahlmann, B; Konrad, K; Poustka, F; Stadler, C; Wöckel, L; Zepf, FD1
Dauvermann, MR; Myint, AM; Oades, RD; Schimmelmann, BG; Schwarz, MJ2
Oades, RD1
Åhlin, A; Bjerkenstedt, L; Fernell, E; Johansson, J; Landgren, M; Venizelos, N; Vumma, R1
Abdel-Hamid, M; Grabemann, M; Kis, B; Kraemer, M; Mette, C; Ueckermann, J; Uekermann, J; Wiltfang, J; Zepf, FD; Zimmermann, M1
Bubenzer, S; Eisert, A; Gaber, TJ; Helmbold, K; Kötting, WF; Zepf, FD1
Brammer, M; Craig, M; Cutter, WJ; Daly, EM; Lamar, M; Murphy, DG; Rubia, K; Tang, C1
Demisch, L; Landgraf, M; Poustka, F; Schmitt, M; Stadler, C; Zepf, FD2
Demisch, L; Holtmann, M; Poustka, F; Schmitt, M; Stadler, C; Wöckel, L; Zepf, FD1
Dramsdahl, M; Haavik, J; Halmøy, A; Johansson, S; Knappskog, PM; McKinney, J; Winge, I1
Holtmann, M; Poustka, F; Wöckel, L; Zepf, FD1
Ghose, K1
Ferguson, HB; Pappas, BA; Peters, DA; Taub, H; Trites, RL1
Belendiuk, K; Freedman, DX; Irwin, M; McCloskey, K1
Comings, DE2
Brase, DA; Loh, HH1
Baker, GB; Bornstein, RA; Carroll, A; Douglass, AB; King, G; Wong, JT1
Comings, BG; Comings, DE; Knell, E1
Barnhill, JL; Chandler, ML; Gualtieri, CT; Patterson, DR1
Arnold, LE; McConnell, H; Nemzer, ED; Votolato, NA1
Hoshino, Y; Kaneko, M; Kumashiro, H; Ohno, Y; Yamamoto, T1

Reviews

3 review(s) available for tryptophan and Attention Deficit Disorder with Hyperactivity

ArticleYear
Tryptophan modulation in individuals with attention deficit hyperactivity disorder: a systematic review.
    Journal of neural transmission (Vienna, Austria : 1996), 2022, Volume: 129, Issue:4

    Topics: Adult; Aggression; Attention Deficit Disorder with Hyperactivity; Child; Humans; Impulsive Behavior; Tryptophan

2022
Does serotonin deficit mediate susceptibility to ADHD?
    Neurochemistry international, 2015, Volume: 82

    Topics: Adolescent; Animals; Animals, Newborn; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Child, Preschool; Corpus Striatum; Disease Models, Animal; Dopamine; Gene-Environment Interaction; Genetic Association Studies; Genetic Predisposition to Disease; Humans; Inhibition, Psychological; Mice, Knockout; Multifactorial Inheritance; Nerve Tissue Proteins; Neurotransmitter Transport Proteins; Oxidopamine; Prefrontal Cortex; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Serotonin, 5-HT1B; Selective Serotonin Reuptake Inhibitors; Serotonin; Tryptophan

2015
Serotonin and the biochemical genetics of alcoholism: lessons from studies of attention deficit hyperactivity disorder (ADHD) and Tourette syndrome.
    Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, 1993, Volume: 2

    Topics: Adult; Alcoholism; Attention Deficit Disorder with Hyperactivity; Child; Female; Genes, Dominant; Genes, Recessive; Humans; Male; Pedigree; Serotonin; Tourette Syndrome; Tryptophan; Tryptophan Oxygenase

1993

Trials

17 trial(s) available for tryptophan and Attention Deficit Disorder with Hyperactivity

ArticleYear
The effects of tryptophan loading on Attention Deficit Hyperactivity in adults: A remote double blind randomised controlled trial.
    PloS one, 2023, Volume: 18, Issue:11

    Topics: Adult; Aggression; Attention Deficit Disorder with Hyperactivity; Double-Blind Method; Humans; Impulsive Behavior; Serotonin; Tryptophan

2023
No effect of acute tryptophan depletion on verbal declarative memory in young persons with ADHD.
    Acta psychiatrica Scandinavica, 2013, Volume: 128, Issue:2

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Central Nervous System; Child; Cross-Over Studies; Diet Therapy; Double-Blind Method; Humans; Male; Mental Recall; Psychological Techniques; Psychotropic Drugs; Reaction Time; Serotonin; Sex Factors; Synaptic Transmission; Treatment Outcome; Tryptophan; Verbal Behavior

2013
The impact of acute tryptophan depletion on attentional performance in adult patients with ADHD.
    Acta psychiatrica Scandinavica, 2013, Volume: 128, Issue:2

    Topics: Adult; Attention; Attention Deficit Disorder with Hyperactivity; Central Nervous System; Cross-Over Studies; Diet Therapy; Double-Blind Method; Humans; Male; Psychological Techniques; Psychotropic Drugs; Reaction Time; Serotonin; Sex Factors; Synaptic Transmission; Treatment Outcome; Tryptophan

2013
No clear effects of acute tryptophan depletion on processing affective prosody in male adults with ADHD.
    Acta psychiatrica Scandinavica, 2013, Volume: 128, Issue:2

    Topics: Adult; Affect; Attention Deficit Disorder with Hyperactivity; Central Nervous System; Cross-Over Studies; Diet Therapy; Double-Blind Method; Humans; Male; Psychological Techniques; Psychotropic Drugs; Reaction Time; Serotonin; Sex Factors; Synaptic Transmission; Treatment Outcome; Tryptophan

2013
Change in electrodermal activity after acute tryptophan depletion associated with aggression in young people with attention deficit hyperactivity disorder (ADHD).
    Journal of neural transmission (Vienna, Austria : 1996), 2014, Volume: 121, Issue:4

    Topics: Adolescent; Aggression; Analysis of Variance; Attention Deficit Disorder with Hyperactivity; Child; Double-Blind Method; Female; Galvanic Skin Response; Humans; Male; Pilot Projects; Psychometrics; Serotonin; Statistics, Nonparametric; Tryptophan

2014
Reduced serotonergic functioning changes heart rate in ADHD.
    Journal of neural transmission (Vienna, Austria : 1996), 2009, Volume: 116, Issue:1

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Case-Control Studies; Child; Cross-Over Studies; Double-Blind Method; Heart Rate; Humans; Impulsive Behavior; Linear Models; Male; Neuropsychological Tests; Serotonin; Tryptophan

2009
Diminished central nervous 5-HT neurotransmission and mood self-ratings in children and adolescents with ADHD: no clear effect of rapid tryptophan depletion.
    Human psychopharmacology, 2009, Volume: 24, Issue:2

    Topics: Adolescent; Affect; Attention Deficit Disorder with Hyperactivity; Central Nervous System; Child; Cross-Over Studies; Double-Blind Method; Humans; Male; Selection Bias; Serotonin; Severity of Illness Index; Time Factors; Tryptophan

2009
Serotonergic neurotransmission and lapses of attention in children and adolescents with attention deficit hyperactivity disorder: availability of tryptophan influences attentional performance.
    The international journal of neuropsychopharmacology, 2010, Volume: 13, Issue:7

    Topics: Adolescent; Attention; Attention Deficit Disorder with Hyperactivity; Central Nervous System; Child; Cross-Over Studies; Double-Blind Method; Humans; Male; Serotonin; Serotonin Agents; Synaptic Transmission; Time Factors; Tryptophan

2010
The effects of acute tryptophan depletion on reactive aggression in adults with attention-deficit/hyperactivity disorder (ADHD) and healthy controls.
    PloS one, 2012, Volume: 7, Issue:3

    Topics: Adult; Aggression; Attention Deficit Disorder with Hyperactivity; Beverages; Case-Control Studies; Humans; Male; Tryptophan

2012
Effects of tryptophan depletion on reactive aggression and aggressive decision-making in young people with ADHD.
    Acta psychiatrica Scandinavica, 2013, Volume: 128, Issue:2

    Topics: Adolescent; Aggression; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior; Cross-Over Studies; Decision Making; Diet Therapy; Double-Blind Method; Female; Humans; Male; Psychological Techniques; Psychotropic Drugs; Serotonin; Sex Factors; Synaptic Transmission; Treatment Outcome; Tryptophan

2013
Acute tryptophan depletion promotes an anterior-to-posterior fMRI activation shift during task switching in older adults.
    Human brain mapping, 2014, Volume: 35, Issue:2

    Topics: Acute Disease; Affect; Aged; Attention Deficit Disorder with Hyperactivity; Brain Mapping; Cognition; Double-Blind Method; Female; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Middle Aged; Neuropsychological Tests; Oxygen; Prefrontal Cortex; Surveys and Questionnaires; Tryptophan

2014
Serotonergic functioning and trait-impulsivity in attention-deficit/hyperactivity-disordered boys (ADHD): influence of rapid tryptophan depletion.
    Human psychopharmacology, 2008, Volume: 23, Issue:1

    Topics: Aggression; Attention Deficit Disorder with Hyperactivity; Child; Cross-Over Studies; Diet, Reducing; Double-Blind Method; Drug Administration Schedule; Humans; Impulsive Behavior; Male; Psychiatric Status Rating Scales; Reaction Time; Serotonin; Tryptophan

2008
Influence of rapid tryptophan depletion on laboratory-provoked aggression in children with ADHD.
    Neuropsychobiology, 2007, Volume: 56, Issue:2-3

    Topics: Adolescent; Aggression; Attention Deficit Disorder with Hyperactivity; Cross-Over Studies; Double-Blind Method; Food, Formulated; Humans; Male; Multivariate Analysis; Psychometrics; Tryptophan

2007
Diminished serotonergic functioning in hostile children with ADHD: tryptophan depletion increases behavioural inhibition.
    Pharmacopsychiatry, 2008, Volume: 41, Issue:2

    Topics: Aggression; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Cross-Over Studies; Double-Blind Method; Hostility; Humans; Inhibition, Psychological; Linear Models; Male; Methylphenidate; Neuropsychological Tests; Psychiatric Status Rating Scales; Psychometrics; Serotonin; Tryptophan

2008
Diminished 5-HT functioning in CBCL pediatric bipolar disorder-profiled ADHD patients versus normal ADHD: susceptibility to rapid tryptophan depletion influences reaction time performance.
    Human psychopharmacology, 2008, Volume: 23, Issue:4

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Child; Child Behavior Disorders; Cross-Over Studies; Double-Blind Method; Humans; Male; Reaction Time; Serotonin; Tryptophan

2008
l-Tryptophan in hyperactive child syndrome associated with epilepsy: a controlled study.
    Neuropsychobiology, 1983, Volume: 10, Issue:2-3

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Carbamazepine; Child; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Epilepsy; Humans; Male; Tryptophan; Valproic Acid

1983
Amino acid supplementation as therapy for attention deficit disorder.
    Journal of the American Academy of Child Psychiatry, 1986, Volume: 25, Issue:4

    Topics: Attention Deficit Disorder with Hyperactivity; Child; Clinical Trials as Topic; Dextroamphetamine; Double-Blind Method; Female; Humans; Male; Random Allocation; Tryptophan; Tyrosine

1986

Other Studies

23 other study(ies) available for tryptophan and Attention Deficit Disorder with Hyperactivity

ArticleYear
Association between cord blood metabolites in tryptophan pathway and childhood risk of autism spectrum disorder and attention-deficit hyperactivity disorder.
    Translational psychiatry, 2022, 07-09, Volume: 12, Issue:1

    Topics: 5-Hydroxytryptophan; Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder; Child; Fetal Blood; Humans; Infant, Newborn; Prospective Studies; Tryptophan

2022
The relationship between central fatigue and Attention Deficit/Hyperactivity Disorder of the inattentive type.
    Neurochemical research, 2022, Volume: 47, Issue:9

    Topics: Amino Acids, Branched-Chain; Attention Deficit Disorder with Hyperactivity; Cognition; Humans; Kynurenic Acid; Quality of Life; Serotonin; Tryptophan

2022
The role of tryptophan metabolic pathway in children with attention deficit hyperactivity disorder with and without comorbid oppositional defiant disorder and conduct disorder.
    Psychiatry research, 2021, Volume: 298

    Topics: Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyperactivity; Child; Comorbidity; Conduct Disorder; Humans; Metabolic Networks and Pathways; Tryptophan

2021
Methylphenidate ameliorates the homeostatic balance between levels of kynurenines in ADHD children.
    Psychiatry research, 2021, Volume: 303

    Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Humans; Kynurenic Acid; Kynurenine; Methylphenidate; Tryptophan

2021
ADHD-originating in the gut? The emergence of a new explanatory model.
    Medical hypotheses, 2018, Volume: 120

    Topics: Animals; Attention Deficit Disorder with Hyperactivity; Brain; Central Nervous System; Ecosystem; Emotions; Enteric Nervous System; Gastrointestinal Microbiome; Gastrointestinal Tract; Humans; Immune System; Mice; Signal Transduction; Tryptophan

2018
Methodology and interpretation of acute tryptophan depletion studies.
    Acta psychiatrica Scandinavica, 2014, Volume: 129, Issue:2

    Topics: Attention Deficit Disorder with Hyperactivity; Diet Therapy; Humans; Male; Mental Recall; Serotonin; Tryptophan; Verbal Behavior

2014
Acute tryptophan depletion - converging evidence for decreasing central nervous serotonin synthesis in rodents and humans.
    Acta psychiatrica Scandinavica, 2014, Volume: 129, Issue:2

    Topics: Attention Deficit Disorder with Hyperactivity; Diet Therapy; Humans; Male; Mental Recall; Serotonin; Tryptophan; Verbal Behavior

2014
Attention-deficit hyperactivity disorder (ADHD) as a pyridoxine-dependent condition: urinary diagnostic biomarkers.
    Medical hypotheses, 2014, Volume: 82, Issue:1

    Topics: Attention Deficit Disorder with Hyperactivity; Biomarkers; Chromatography, High Pressure Liquid; Humans; Methylphenidate; Models, Biological; Pyridoxine; Tryptophan

2014
No Tryptophan, Tyrosine and Phenylalanine Abnormalities in Children with Attention-Deficit/Hyperactivity Disorder.
    PloS one, 2016, Volume: 11, Issue:3

    Topics: Adolescent; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder; Case-Control Studies; Child; Conduct Disorder; Diet; Dietary Proteins; Female; Humans; Male; Netherlands; Phenylalanine; Surveys and Questionnaires; Tryptophan; Tyrosine

2016
Resting state default mode network connectivity in children and adolescents with ADHD after acute tryptophan depletion.
    Acta psychiatrica Scandinavica, 2016, Volume: 134, Issue:2

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Brain; Brain Mapping; Child; Humans; Magnetic Resonance Imaging; Male; Neural Pathways; Rest; Serotonin; Tryptophan

2016
Attention-deficit hyperactivity disorder (ADHD) and glial integrity: S100B, cytokines and kynurenine metabolism--effects of medication.
    Behavioral and brain functions : BBF, 2010, May-28, Volume: 6

    Topics: Adolescent; Amino Acids; Attention Deficit Disorder with Hyperactivity; Brain; Central Nervous System Stimulants; Child; Cytokines; Energy Metabolism; Female; Humans; Kynurenine; Male; Nerve Growth Factors; Neuroglia; Pilot Projects; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Tryptophan

2010
Attention-deficit hyperactivity disorder (ADHD) and glial integrity: an exploration of associations of cytokines and kynurenine metabolites with symptoms and attention.
    Behavioral and brain functions : BBF, 2010, Jun-09, Volume: 6

    Topics: Adolescent; Attention; Attention Deficit Disorder with Hyperactivity; Case-Control Studies; Child; Cytokines; Female; Humans; Interleukins; Kynurenine; Linear Models; Male; Motor Activity; Neuroglia; Neuropsychological Tests; Psychiatric Status Rating Scales; Psychomotor Performance; Reaction Time; Tryptophan

2010
An exploration of the associations of pregnancy and perinatal features with cytokines and tryptophan/kynurenine metabolism in children with attention-deficit hyperactivity disorder (ADHD).
    Attention deficit and hyperactivity disorders, 2011, Volume: 3, Issue:4

    Topics: Adult; Alcohol Drinking; Attention Deficit Disorder with Hyperactivity; Case-Control Studies; Child; Child Care; Cytokines; Diagnostic and Statistical Manual of Mental Disorders; Female; Humans; Kynurenine; Male; Mothers; Pregnancy; Pregnancy Complications; Smoking; Tryptophan

2011
Altered tryptophan and alanine transport in fibroblasts from boys with attention-deficit/hyperactivity disorder (ADHD): an in vitro study.
    Behavioral and brain functions : BBF, 2011, Sep-24, Volume: 7

    Topics: Alanine; Attention Deficit Disorder with Hyperactivity; Blood-Brain Barrier; Cells, Cultured; Child; Fibroblasts; Humans; Male; Protein Transport; Tryptophan

2011
A loss-of-function mutation in tryptophan hydroxylase 2 segregating with attention-deficit/hyperactivity disorder.
    Molecular psychiatry, 2008, Volume: 13, Issue:4

    Topics: Arginine; Attention Deficit Disorder with Hyperactivity; Base Sequence; Cell Line, Transformed; Family Health; Female; Humans; Male; Mutation; Norway; Tryptophan; Tryptophan Hydroxylase

2008
Plasma free and total tryptophan, blood serotonin, and the hyperactivity syndrome: no evidence for the serotonin deficiency hypothesis.
    Biological psychiatry, 1981, Volume: 16, Issue:3

    Topics: Attention Deficit Disorder with Hyperactivity; Child; Double-Blind Method; Female; Humans; Hydrocortisone; Male; Methylphenidate; Serotonin; Tryptophan

1981
Tryptophan metabolism in children with attentional deficit disorder.
    The American journal of psychiatry, 1981, Volume: 138, Issue:8

    Topics: Adolescent; Adult; Attention; Attention Deficit Disorder with Hyperactivity; Blood Platelets; Child; Child, Preschool; Dextroamphetamine; Humans; Intelligence; Kynurenine; Methylphenidate; Protein Binding; Serotonin; Tryptophan

1981
Possible role of 5-hydroxyptamine in minimal brain dysfunction.
    Life sciences, 1975, Apr-01, Volume: 16, Issue:7

    Topics: Amphetamine; Animal Nutritional Physiological Phenomena; Animals; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Child; Drug Interactions; Fenclonine; Humans; Hyperkinesis; Norepinephrine; Phenylketonurias; Serotonin; Tryptophan

1975
Plasma amino acids in attention deficit disorder.
    Psychiatry research, 1990, Volume: 33, Issue:3

    Topics: Amino Acids; Attention Deficit Disorder with Hyperactivity; Child; Female; Histidine; Humans; Isoleucine; Male; Phenylalanine; Tryptophan; Tyrosine

1990
Blood serotonin and tryptophan in Tourette syndrome.
    American journal of medical genetics, 1990, Volume: 36, Issue:4

    Topics: Adult; Aging; Attention Deficit Disorder with Hyperactivity; Child; Cloning, Molecular; Fasting; Female; Homozygote; Humans; Intestines; Liver; Male; Mental Disorders; Platelet Count; Serotonin; Sex Factors; Tourette Syndrome; Tryptophan; Tryptophan Oxygenase

1990
Hypothesis: homozygosity in Tourette syndrome.
    American journal of medical genetics, 1989, Volume: 34, Issue:3

    Topics: Adult; Attention Deficit Disorder with Hyperactivity; Child; Epistasis, Genetic; Female; Genetic Linkage; Homozygote; Humans; Male; Mental Disorders; Obsessive-Compulsive Disorder; Panic; Pedigree; Serotonin; Substance-Related Disorders; Tic Disorders; Tourette Syndrome; Tryptophan

1989
Tryptophan antagonism of stimulant-induced tics.
    Journal of clinical psychopharmacology, 1989, Volume: 9, Issue:1

    Topics: Attention Deficit Disorder with Hyperactivity; Child; Drug Therapy, Combination; Humans; Male; Methylphenidate; Tic Disorders; Tryptophan

1989
Plasma free tryptophan concentration in children with attention deficit disorder.
    Folia psychiatrica et neurologica japonica, 1985, Volume: 39, Issue:4

    Topics: Attention Deficit Disorder with Hyperactivity; Brain; Child; Child, Preschool; Female; Humans; Male; Serotonin; Tryptophan

1985