tryptophan has been researched along with Astrocytoma, Grade IV in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (6.90) | 18.7374 |
| 1990's | 3 (10.34) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 15 (51.72) | 24.3611 |
| 2020's | 9 (31.03) | 2.80 |
| Authors | Studies |
|---|---|
| Acharya, R; Bao, R; Bell, A; Bollu, L; Chen, P; Clark, SJ; Genet, M; Griffiths, J; Horbinski, C; Kim, M; Ladomersky, E; Lauing, KL; Lukas, RV; Mi, X; Nguyen, B; Schiltz, GE; Schipma, MJ; Unwin, RD; Wainwright, DA; Wray, B; Wu, JD; Zhai, L | 1 |
| Hosseinalizadeh, H; Mahmoodpour, M; Roudkenar, MH; Samadani, AA | 1 |
| Morawiak, M; Sowińska, M; Szeliga, M; Urbanczyk-Lipkowska, Z; Zabłocka, B | 1 |
| Buelow, KL; Chinnaiyan, P; Kant, S; Kesarwani, P; Miller, CR; Prabhu, A; Zhao, Y | 1 |
| Boucher, P; Chiocca, EA; Finkelberg, T; Jimenez-Macias, JL; Koch, MS; Lawler, SE; Li, W; Ling, AL; Manz, KE; Nowicki, MO; Pennell, KD; Piranlioglu, R; Takeda, Y; Wu, B; Zdioruk, M | 1 |
| Dietze, J; Heiland, I; Mohapatra, SR; Opitz, CA; Poschet, G; Sadik, A; Tykocinski, LO | 1 |
| Classen, CF; Domanska, G; Gesche, J; Irmscher, N; Junghanss, C; Kehnscherper, H; Maletzki, C; Riess, C; Schneider, B; Shokraie, F; Strüder, D; Wirthgen, E; Zimpfer, A | 1 |
| Ahlstedt, J; Ceberg, C; Konradsson, E; Redebrandt, HN | 1 |
| Choudhuri, KSR; Mishra, S | 1 |
| Morawiak, M; Sowińska, M; Szeliga, M; Urbańczyk-Lipkowska, Z; Zabłocka, B; Ziemińska, E | 1 |
| Helson, L; Sordillo, LA; Sordillo, PP | 1 |
| Chinnaiyan, P; Kant, S; Kesarwani, P; Prabhu, A | 2 |
| Ahlstedt, J; Ceberg, C; Chakwizira, A; Nittby Redebrandt, H | 1 |
| Amit-Yousif, AJ; Barger, GR; Bosnyák, E; John, F; Juhász, C; Klinger, NV; Michelhaugh, SK; Mittal, S; Robinette, NL; Shah, KD | 1 |
| James, CD; Juhász, C; Kennedy, E; Lesniak, MS; Lukas, RV; Stupp, R; Wainwright, DA | 1 |
| Blaes, J; Bunse, L; Litzenburger, UM; Ochs, K; Opitz, CA; Ott, M; Platten, M; Pusch, S; Rauschenbach, KJ; Sahm, F; von Deimling, A; Wick, W | 1 |
| Bloch, O; Dey, M; Dostal, CR; Gritsina, G; Kaur, R; Lauing, KL; Lukas, RV; McCusker, RH; Nicholas, MK; Parsa, AT; Rademaker, AW; Raizer, JJ; Wainwright, DA; Zhai, L | 1 |
| Barger, GR; Bosnyák, E; Juhász, C; Kamson, DO; Mittal, S; Robinette, NL | 1 |
| Bassett, E; Chakravarti, A; Fischer, SM; Gordon, N; Jacob, JR; Kanji, S; Lautenschlaeger, T; Litzenberg, KT; Palanichamy, K; Patel, D; Ramasubramanian, B; Ray-Chaudhury, A; Sebastian, N; Singh, R; Thirumoorthy, K | 1 |
| Guastella, AR; Juhász, C; Klinger, NV; Kupsky, WJ; Michelhaugh, SK; Mittal, S; Muzik, O; Polin, LA | 1 |
| Genet, M; Gritsina, G; James, CD; Ladomersky, E; Lauing, KL; Wainwright, DA; Wu, M; Zhai, L | 1 |
| Barger, GR; Bosnyák, E; Juhász, C; Kamson, DO; Klinger, NV; Michelhaugh, SK; Mittal, S | 1 |
| Colman, H; Conrad, CA; Devakumar, A; Dillon, R; Greig, M; Ji, Y; Kaboord, BJ; Kilmer, G; Krastins, B; Lang, FF; Lopez, M; Major, M; Nilsson, CL; Prakash, A; Priebe, W; Rezai, T; Rogers, JC; Rosenblatt, M; Sarracino, D; Shi, SD | 1 |
| Gibbs, WD; Hübner, KF; King, P; Mahaley, SM; Partain, CL; Purvis, JT; Robertson, JT; Rogers, S | 1 |
| Boni, RL; Markey, SP; Naritsin, DB; Saito, K; Simpson, JT | 1 |
| Däubener, W; Hadding, U; Mackenzie, C; Nockemann, S; Pilz, K; Remscheid, C; Seghrouchni, S | 1 |
| Däubener, W; Mackenzie, CR; Willberg, CB | 1 |
| Abdullakhozhaeva, MS; Dimant, IN; Faĭn, NG | 1 |
3 review(s) available for tryptophan and Astrocytoma, Grade IV
| Article | Year |
|---|---|
The immunosuppressive role of indoleamine 2, 3-dioxygenase in glioblastoma: mechanism of action and immunotherapeutic strategies.
Topics: Adult; Brain Neoplasms; Glioblastoma; Humans; Immunotherapy; Indoleamine-Pyrrole 2,3,-Dioxygenase; Prospective Studies; Tryptophan | 2022 |
The Kynurenine Pathway: A Primary Resistance Mechanism in Patients with Glioblastoma.
Topics: Animals; Antineoplastic Agents; Cytokines; Drug Resistance, Neoplasm; Glioblastoma; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Signal Transduction; Tryptophan; Tryptophan Oxygenase | 2017 |
The interplay between metabolic remodeling and immune regulation in glioblastoma.
Topics: Glioblastoma; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Signal Transduction; Tryptophan; Tryptophan Oxygenase | 2017 |
26 other study(ies) available for tryptophan and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Tumor Cell IDO Enhances Immune Suppression and Decreases Survival Independent of Tryptophan Metabolism in Glioblastoma.
Topics: Animals; Glioblastoma; Glioma; Humans; Immunosuppression Therapy; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Tryptophan | 2021 |
Design, Synthesis and Activity of New
Topics: Antioxidants; Cell Line, Tumor; Dendrimers; Glioblastoma; Humans; Peptides; Reactive Oxygen Species; Tryptophan | 2022 |
Quinolinate promotes macrophage-induced immune tolerance in glioblastoma through the NMDAR/PPARγ signaling axis.
Topics: Animals; Biological Products; Brain Neoplasms; Glioblastoma; Immune Tolerance; Macrophages; Mice; Neurodegenerative Diseases; PPAR gamma; Quinolinic Acid; Receptors, N-Methyl-D-Aspartate; Tryptophan; Tumor Microenvironment | 2023 |
PPRX-1701, a nanoparticle formulation of 6'-bromoindirubin acetoxime, improves delivery and shows efficacy in preclinical GBM models.
Topics: Animals; Glioblastoma; Kynurenine; Mice; Oximes; Tryptophan | 2023 |
Hypoxia Inducible Factor 1α Inhibits the Expression of Immunosuppressive Tryptophan-2,3-Dioxygenase in Glioblastoma.
Topics: Brain Neoplasms; Cell Hypoxia; Cell Line, Tumor; Gene Expression Regulation, Enzymologic; Glioblastoma; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immune Tolerance; Kynurenine; Lymphocyte Activation; T-Lymphocytes; Tryptophan; Tryptophan Oxygenase | 2019 |
Activation of the Kynurenine Pathway in Human Malignancies Can Be Suppressed by the Cyclin-Dependent Kinase Inhibitor Dinaciclib.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Squamous Cell; Cell Line, Tumor; Cyclic N-Oxides; Cyclin-Dependent Kinases; Gene Expression Regulation, Neoplastic; Glioblastoma; Head and Neck Neoplasms; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Indolizines; Interferon-gamma; Kynurenine; Metabolic Networks and Pathways; Neoplasms; Pyridinium Compounds; Tryptophan; Tryptophan Oxygenase | 2020 |
Increased effect of two-fraction radiotherapy in conjunction with IDO1 inhibition in experimental glioblastoma.
Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Enzyme Inhibitors; Gene Expression; Glioblastoma; Indoleamine-Pyrrole 2,3,-Dioxygenase; Rats; Rats, Inbred F344; Tryptophan; Tumor Microenvironment | 2020 |
Structural basis of BMP-2 and BMP-7 interactions with antagonists Gremlin-1 and Noggin in Glioblastoma tumors.
Topics: Binding Sites; Bone Morphogenetic Protein 2; Bone Morphogenetic Protein 7; Carrier Proteins; Glioblastoma; Histidine; Humans; Intercellular Signaling Peptides and Proteins; Models, Molecular; Protein Binding; Protein Conformation; Thermodynamics; Tryptophan | 2020 |
Peptide Dendrimers with Non-Symmetric Bola Structure Exert Long Term Effect on Glioblastoma and Neuroblastoma Cell Lines.
Topics: Animals; Antioxidants; Carbon-13 Magnetic Resonance Spectroscopy; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dendrimers; Free Radical Scavengers; Glioblastoma; Humans; Neuroblastoma; Neurons; Peptides; Proton Magnetic Resonance Spectroscopy; Rats, Wistar; Reactive Oxygen Species; Tryptophan | 2021 |
Mathematical modelling of the synergistic combination of radiotherapy and indoleamine-2,3-dioxygenase (IDO) inhibitory immunotherapy against glioblastoma.
Topics: Animals; Combined Modality Therapy; Disease Models, Animal; Dose Fractionation, Radiation; Glioblastoma; Immunotherapy; Indoleamine-Pyrrole 2,3,-Dioxygenase; Models, Theoretical; Rats; Rats, Inbred F344; Tryptophan | 2018 |
Multimodal imaging-defined subregions in newly diagnosed glioblastoma: impact on overall survival.
Topics: Diffusion Magnetic Resonance Imaging; Disease Progression; Female; Follow-Up Studies; Glioblastoma; Humans; Male; Middle Aged; Multimodal Imaging; Neoplasm Recurrence, Local; Positron-Emission Tomography; Prognosis; Survival Rate; Tryptophan | 2019 |
Imaging tryptophan uptake with positron emission tomography in glioblastoma patients treated with indoximod.
Topics: Adult; Brain; Brain Neoplasms; Female; Glioblastoma; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Magnetic Resonance Imaging; Male; Middle Aged; Positron-Emission Tomography; Tryptophan | 2019 |
Metabolic remodeling contributes towards an immune-suppressive phenotype in glioblastoma.
Topics: Adenosine; Adult; Animals; Brain; Brain Neoplasms; Cell Line, Tumor; Gene Expression Profiling; Glioblastoma; Humans; Macrophages; Metabolic Networks and Pathways; Metabolome; Metabolomics; Mice; Mice, Inbred C57BL; T-Lymphocytes, Regulatory; Tryptophan | 2019 |
Suppression of TDO-mediated tryptophan catabolism in glioblastoma cells by a steroid-responsive FKBP52-dependent pathway.
Topics: Aging; Animals; Cell Line, Tumor; Dexamethasone; Glioblastoma; Humans; Mice; Signal Transduction; Tacrolimus; Tacrolimus Binding Proteins; Tryptophan; Tryptophan Oxygenase | 2015 |
The kynurenine to tryptophan ratio as a prognostic tool for glioblastoma patients enrolling in immunotherapy.
Topics: Adult; Aged; Biomarkers, Tumor; Female; Glioblastoma; Humans; Immunotherapy; Kynurenine; Male; Middle Aged; Prognosis; Treatment Outcome; Tryptophan | 2015 |
Tryptophan PET predicts spatial and temporal patterns of post-treatment glioblastoma progression detected by contrast-enhanced MRI.
Topics: Aged; Brain; Brain Neoplasms; Contrast Media; Disease Progression; Female; Glioblastoma; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Multimodal Imaging; Positron-Emission Tomography; Tryptophan | 2016 |
Methionine and Kynurenine Activate Oncogenic Kinases in Glioblastoma, and Methionine Deprivation Compromises Proliferation.
Topics: Astrocytes; Biomarkers, Tumor; Carcinogenesis; Cell Line; Cell Proliferation; Chromatography, High Pressure Liquid; Glioblastoma; Humans; Kynurenine; Mass Spectrometry; Metabolomics; Methionine; Oncogenes; Purine-Nucleoside Phosphorylase; Tryptophan; Tumor Cells, Cultured | 2016 |
Tryptophan PET Imaging of the Kynurenine Pathway in Patient-Derived Xenograft Models of Glioblastoma.
Topics: Aged; Animals; Biosynthetic Pathways; Brain Neoplasms; Carbon Radioisotopes; Cell Line, Tumor; Female; Glioblastoma; Humans; Kynurenine; Male; Mice; Middle Aged; Molecular Imaging; Neoplasm Transplantation; Positron-Emission Tomography; Tryptophan | 2016 |
Advanced age negatively impacts survival in an experimental brain tumor model.
Topics: Aging; Animals; Brain Neoplasms; Cell Line, Tumor; Disease Models, Animal; Glioblastoma; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Lymphocytes, Tumor-Infiltrating; Mice; Mice, Inbred C57BL; Survival Analysis; Tryptophan | 2016 |
Prognostic Molecular and Imaging Biomarkers in Primary Glioblastoma.
Topics: Aged; Biomarkers, Tumor; Carbon Radioisotopes; Central Nervous System Neoplasms; DNA Methylation; ErbB Receptors; Female; Glioblastoma; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Mutation; Positron-Emission Tomography; Prognosis; Promoter Regions, Genetic; Tryptophan | 2017 |
Quantitative phosphoproteomic analysis of the STAT3/IL-6/HIF1alpha signaling network: an initial study in GSC11 glioblastoma stem cells.
Topics: Blotting, Western; Chemokines; Chromatography, Liquid; Glioblastoma; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Interleukin-6; Models, Biological; Neoplastic Stem Cells; Nitric Oxide Synthase Type II; Phosphopeptides; Phosphoproteins; Phosphorylation; Proteome; Signal Transduction; STAT3 Transcription Factor; Tandem Mass Spectrometry; Tryptophan | 2010 |
Brain tumor imaging by positron emission computed tomography using 11C-labeled amino acids.
Topics: Adult; Aged; Amino Acids; Astrocytoma; Brain Neoplasms; Carbon Radioisotopes; Ependymoma; Female; Glioblastoma; Glioma; Humans; Male; Meningioma; Middle Aged; Tomography, Emission-Computed; Tryptophan; Valine | 1982 |
Quantification of L-tryptophan and L-kynurenine by liquid chromatography/electron capture negative ion chemical ionization mass spectrometry.
Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Chromatography, Liquid; Fluorobenzenes; Gerbillinae; Glioblastoma; Humans; In Vitro Techniques; Interferon-gamma; Kynurenine; Lung; Mass Spectrometry; Mice; Mice, Inbred C57BL; Monocytes; Nervous System Neoplasms; Reference Standards; Spectrophotometry, Ultraviolet; Tryptophan; Tumor Cells, Cultured | 1994 |
Anti-parasitic effector mechanisms in human brain tumor cells: role of interferon-gamma and tumor necrosis factor-alpha.
Topics: Animals; Astrocytes; Brain Neoplasms; Drug Synergism; Enzyme Induction; Glioblastoma; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Toxoplasma; Tryptophan; Tryptophan Oxygenase; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1996 |
Inhibition of group B streptococcal growth by IFN gamma-activated human glioblastoma cells.
Topics: Glioblastoma; Humans; Interferon-gamma; Meningitis, Bacterial; Streptococcus agalactiae; Streptococcus pneumoniae; Tryptophan; Tryptophan Oxygenase; Tumor Cells, Cultured | 1998 |
[Data towards the histochemical characteristics of brain tumors in rats].
Topics: Animals; Arachnoid; Astrocytoma; Brain Neoplasms; DNA; Ependymoma; Glioblastoma; Glioma; Hemangioendothelioma; Histidine; Neoplasms, Experimental; Oligodendroglioma; Protein Biosynthesis; Rats; RNA; Tryptophan; Tyrosine | 1966 |