tryptophan and Anxiety

tryptophan has been researched along with Anxiety in 117 studies

Research

Studies (117)

TimeframeStudies, this research(%)All Research%
pre-199012 (10.26)18.7374
1990's15 (12.82)18.2507
2000's26 (22.22)29.6817
2010's46 (39.32)24.3611
2020's18 (15.38)2.80

Authors

AuthorsStudies
Ataei, S; Azcarate-Peril, A; Carroll, I; Fransson, E; Jin, W; Kimmel, M; Knickmeyer, R; Lun, K; Meltzer-Brody, S; Plantinga, A; Rackers, H; Wu, M; Xia, K1
Ahmad, S; Alam, M; Azizuddin, -; Khaliq, S; Mustafa, S; Raza, U; Samad, N; Yasmin, F1
Aranyi, CS; Bagdy, G; Baksa, D; Dobos, D; Emri, M; Galambos, A; Gecse, K; Juhasz, G; Kocsel, N; Kökönyei, G; Ludányi, K; Pap, D; Szabó, E; Virág, D1
Cheng, HW; Feng, Z; Huang, X1
Bernardoni, F; Boehm, I; Ehrlich, S; King, J; Mannigel, M; Ritschel, F; Roessner, V; Steding, J; Weinert, T; Zepf, F1
Bai, W; Liu, X; Lu, L; Pan, W; Shi, R; Wang, D; Wang, Y; Wu, J; Xia, B; Xie, H; Ye, J; Zhao, B; Zhao, Z; Zhu, P1
Buyukkoruk, M; Candansayar, S; Deveci-Bulut, TS; Gulbahar, O; Kucukkarapinar, M; Senol, E; Yay-Pence, A; Yaz-Aydin, G; Yildiz, Y1
Aguesse, A; Bolaños-Jiménez, F; Cagni, FC; Costa, LRF; Croyal, M; Gavioli, EC; Moura, CA; Reyes-Castro, LA; Tiago, PRF; Zambrano, E1
Bobrovskaya, L; Herselman, MF; Lin, L; Luo, S; Yamanaka, A; Zhou, XF1
Badawy, AA; Bano, S; Hamid, SB; Sajid, F; Sharif, H1
Abed, AK; Al-Hakeim, HK; Almulla, AF; Maes, M; Rouf Moustafa, S1
Cui, C; Li, W; Liu, S; Sun-Waterhouse, D; Tao, Q; Zhu, X1
Barcellos, LJG; Bonan, CD; de Abreu, MS; Genario, R; Giacomini, ACVV; Piassetta, AS; Piato, A1
Erhardt, S; Goiny, M; Imbeault, S; Liu, X1
Leyva-Vela, B; Martínez-Rodríguez, A; Nadal-Nicolás, Y; Ramos-Campo, DJ; Reche-García, C; Rubio-Arias, JÁ1
Comai, S; Frigerio, A; Molteni, M; Nazzari, S; Valtorta, F1
Aprano, S; Barrea, L; Castellucci, B; Colao, A; Laudisio, D; Muscogiuri, G; Pugliese, G; Savastano, S1
Brown, J; Clarke, G; Collins, JM; Cryan, JF; Dinan, TG; Keane, JM; Kenny, LC; Khashan, AS; McCarthy, FP; O'Donovan, S; O'Mahony, SM1
Batelaan, NM; Bosman, RC; Muntingh, ADT; Schopman, SME; van Balkom, AJLM1
Abautret-Daly, Á; Connor, TJ; de Francisco-García, R; Dempsey, E; Harkin, A; Medina, C; Parra-Blanco, A; Riestra, S; Rodrigo, L1
Ahmed, M; Azmat, A1
Chamoto, K; Fagarasan, S; Furukawa, T; Guerrini, MM; Hikida, T; Honda, K; Honjo, T; Ishihama, Y; Ito, S; Maruya, M; Matsuda, F; Miyajima, M; Qin, H; Sanuki, R; Sonomura, K; Suematsu, M; Sugiura, Y; Suzuki, K; Tsutsui, Y; Vogelzang, A; Zhang, B1
Broyd, A; Hince, DA; Hood, SD; Hudaib, AR; Lee, J; Robinson, H1
Carvalho, AF; Geffard, M; Kanchanatawan, B; Maes, M; Sirivichayakul, S; Thika, S1
Funakoshi, H; Hattori, S; Miyakawa, T; Takao, K1
Carvalho, AF; Kanchanatawan, B; Maes, M; Sirivichayakul, S; Thika, S1
Kanchanatawan, B; Maes, M; Sriswasdi, S1
Chang, WH; Chen, KC; Chen, PS; Chi, MH; Lee, IH; Lin, SH; Tsai, HC; Yang, YK1
Allen, PS; Grillon, C; Letkiewicz, A; Overstreet, C; Pine, DS; Robinson, OJ; Vytal, K1
Bialonska, D; Lewellyn, K; Loria, MJ; Sufka, KJ; White, SW; Zjawiony, JK1
Berthoz, S; Bioulac, S; Bouvard, M; Callebert, J; Delorme, M; Falissard, B; Gauthier, C; Gerardin, P; Godart, N; Hassler, C; Lang, F; Launay, JM; Mattar, L; Melchior, JC; Mourier-Soleillant, V; Pommereau, X; Steiger, H1
Aguilera-Pérez, R; Flores-Ramos, M; Heinze, G; Moreno, J; Pellicer Graham, F1
Capello, AE; Markus, CR1
Kato, M; Miyaji, K; Ohta, M; Ohtani, N1
Baker, G; Madsen, KL; Ohland, CL; Pankiv, E1
Bernik, M; Corchs, F; Davies, SJ; Hince, DA; Hood, SD; Nutt, DJ1
Asor, E; Avital, A; Ben-Shachar, D; Klein, E; Ruppin, E; Stempler, S1
Furuse, M; Goda, R; Iwamoto, A; Kawai, M; Mizunoya, W; Oka, Y; Otsuka, T; Shibata, S; Yasuo, S1
Botanas, CJ; Cheong, JH; de la Peña, JB; dela Peña, IJ; Hong, E; Hong, YS; Hwang, YS; Kim, HJ; Moon, BS1
Hoshi, R; Igarashi, T; Kato-Kataoka, A; Kawai, M; Kushiro, A; Kuwano, Y; Miyazaki, K; Nishida, K; Rokutan, K; Shimizu, K; Suda, K; Takada, M; Watanabe, O1
Hanhineva, K; Lehtonen, M; Lohi, H; Puurunen, J; Tiira, K1
Antunes, MS; Boeira, SP; de Oliveira Espinosa, D; Donato, F; Giacomeli, R; Gomes, NS; Jesse, CR; Ruff, JR; Souza, LC1
Chen, KC; Chen, PS; Chi, MH; Hsiao, CY; Lee, IH; Tsai, HC; Yang, YK; Yeh, TL1
Budac, DP; Elfving, B; Eskelund, A; Sanchez, C; Wegener, G1
Argyropoulos, SV; Bell, CJ; Hood, SD; Nutt, DJ1
Baccarelli, AA; Degroote, S; Hunting, DJ; Takser, L1
Dayan, P; Dolan, RJ; Faulkner, P; Lockwood, PL; Mancinelli, F; Matarin, M; Roiser, JP; Wood, NW1
de Rivera, C; Kelly, S; Landsberg, G; Milgram, B; Mougeot, I1
Davies, N; Hilder, EF; Jose, MD; Karu, N; McKercher, C; Nichols, DS; Shellie, RA1
Arboleya, S; Burokas, A; Clarke, G; Cryan, JF; Dinan, TG; Moloney, RD; Murphy, K; Peterson, VL; Stanton, C1
Anderson, G; Carvalho, AF; Geffard, M; Ivanova, R; Kanchanatawan, B; Maes, M; Noto, C; Ruxrungtham, K; Sirivichayakul, S; Thika, S1
Blokland, A; Jans, LA1
Blokland, A; Jans, LA; Korte, SM; Korte-Bouws, GA1
Funakoshi, H; Hayakawa, T; Kanai, M; Matsumoto, K; Mizuno, S; Nakamura, T; Takahashi, H1
Haider, S; Haleem, DJ; Kanwal, S; Perveen, T1
Dunn, AJ; Roberts, AJ; Wang, J; Zhang, H1
Adrover, M; Argyropoulos, S; Bell, C; Frampton, C; Hince, D; Hood, S; Nash, J; Nutt, D; Potokar, J; Rich, A1
Bandelow, B; Engel, K; Falkai, P; Havemann-Reinecke, U; Herchenhein, T; Kirchhainer, J; Malchow, B; Wedekind, D1
Bercik, P; Bergonzelli, GE; Blennerhassett, P; Cherbut, C; Collins, SM; Corthesy-Theulaz, I; Foster, JA; Huang, X; Jackson, W; Khan, WI; Lu, J; Macri, J; Malinowski, P; Neufeld, KA; Potter, M; Verdu, EF1
Benkelfat, C; Coderre, E; Dumas, J; Naylor, M; Newhouse, PA; Sites, CK; Wilkins, H; Young, SN1
Boesmans, W; Geeraerts, B; Tack, J; Van Oudenhove, L; Vanden Berghe, P; Vos, R1
Barone, PR; Belzung, C; Callebert, J; Laugeray, A; Launay, JM; Surget, A1
Ando, Y; Isobe, K; Miura, H; Noda, Y; Ozaki, N1
Amaral, FU; de Oliveira, DL; Giacomini, AC; Guedes, FS; Hansel, G; Hansen, F; Schmidt, KH; Schneider, TJ; Torres, FV; Tumelero, AC1
Clark, L; Crockett, MJ; Robbins, TW; Smillie, LD1
Allen, PS; Grillon, C; Overstreet, C; Pine, DS; Robinson, OJ1
Ali, SF; Fiore, M; Laviola, G; Macrì, S; Zoratto, F1
Coppola, A; Ilkayeva, O; Levin, ED; Maggioni, M; Newgard, CB; Slotkin, TA; Stevens, RD; Wenner, BR1
Bonaccorso, S; Bosmans, E; Maes, M; Ombelet, W; Scharpé, S; Verkerk, R1
Barbarich, NC; Fernstrom, J; Fernstrom, M; Gendall, KA; Kaye, WH; Kishore, A; McConaha, CW; Putnam, K1
Capuron, L; Fuchs, D; Lawson, DH; Miller, AH; Musselman, DL; Nemeroff, CB; Neurauter, G1
Sanders-Bush, E; Sodhi, MS1
Adrover, M; Argyropoulos, SV; Bell, CJ; Hood, SD; Nash, JR; Nutt, DJ; Rich, AS; Rich, NC; Witchel, HJ1
Knechtle, B1
Payne, JK1
Corona-Morales, AA; Escobar, A; Guadarrama, L; Rocha, L; Vega-Gonzalez, A; Zhang, L1
Abrams, JK; Bouwknecht, JA; Evans, AK; Knight, DM; Lowry, CA; Shekhar, A1
Aldinucci, A; Biagiotti, T; Carpendo, R; Cozzi, A; Giannini, C; Laffi, G; Monti, M; Moroni, F; Rosselli, M; Zignego, AL1
Christmas, D; Cirillo, M; Hince, DA; Hood, SD; Kaye, JM; Robinson, H1
Hendry, J; Hince, DA; Hood, S; Morris, K; Nutt, D; Potokar, J; Probert, C; Shufflebotham, J1
Brocke, B; Escher, A; Gross, C; Gutknecht, L; Jacob, C; Kriegebaum, C; Lesch, KP; Markert, C; Mössner, R; Müller, J; Reif, A; Strobel, A; Wendland, J; Zeng, Y1
Blokland, A; Jans, LA; Lieben, CK1
Moreira, JD; Pereira, AG; Perry, ML; Portela, LV; Rieger, DK; Siqueira, IR; Souza, CG; Souza, DO; Souza, TM1
Kopasz, M; Külz, AK; Meinzer, S; Voderholzer, U1
Lue, FA; Moldofsky, H1
Banki, CM; Molnar, G; Vojnik, M1
Hoyse, SE1
Charney, DS; Germine, M; Goddard, AW; Goodman, WK; Heninger, GR; Krystal, JH; Price, LH; Woods, SW1
Bond, AJ; Cleare, AJ1
Clauw, DJ; Hertzman, PA; Kaufman, LD; Love, LA; Mease, PJ; Philen, RM; Pincus, T; Rosenberg, NL; Silver, R; Varga, J1
Fernstrom, JD; Kaye, WH; McConaha, C; Weltzin, TE1
Delgado, PL; Gelenberg, AJ; Laukes, C; Moreno, F; Strayer, L1
Aguerre, S; Berton, O; Chaouloff, F; Mormede, P; Sarrieau, A1
Deutz, NE; Griez, E; Klaassen, T; Klumperbeek, J; van Praag, HM1
Bond, AJ; Cleare, AJ; Sherwood, R; Wingrove, J1
Bond, AJ; Cleare, AJ; Wingrove, J1
Anderson, IM; Mortimore, C1
Baker, GB; Benkelfat, C; Blier, P; Etezadi, S; Lauze, C; Leyton, M; Pihl, RO; Young, SN1
Deutz, NE; Griez, E; Klaassen, T; Overbeek, T; Pols, H; Schruers, K1
dos-Santos, JE; Graeff, FG; Guimarães, FS; Monteiro-dos-Santos, PC; Ribeiro, RP; Zuardi, AW1
Busnello, JV; Forster, L; Izquierdo, I; Kapczinski, F; Quevedo, J; Shansis, FM; Young, S1
Ong, YP; Wong, PT1
Gurevich, KG; Surkina, ID1
Blokland, A; Deutz, NE; Lieben, C1
Allgén, LG; Backman, L; Hallberg, D; Johansson, C; Thor'en, P1
Bartlett, JR; Bellamy, C; Bridges, PK; O'Gormann, P; Patel, VK; Sepping, P; Wood, W1
Erb, JL; Hendrie, HC; Ward, VL1
Bruce, A; Herrington, RN; Johnstone, EC; Lader, MH1
Bjorn-Erik, R; Carlsson, A; Nagy, A; Skott, A; Walinder, J1
Cowen, PJ; Power, AC1
Beams, RM; Critchley, MA; Hodson, HF; Iyer, R; Knowles, RG; Madge, DJ; Pogson, CI; Salter, M1
Bowen, DJ; Fox, E; Spring, B1
Ekblom, A; Hansson, P; Thomsson, M1
Lester, D1
Lader, M1
Angel, C; DeLuca, DC; Murphree, OD1
Cowen, MA1

Reviews

10 review(s) available for tryptophan and Anxiety

ArticleYear
A practical nutritional guide for the management of sleep disturbances in menopause.
    International journal of food sciences and nutrition, 2021, Volume: 72, Issue:4

    Topics: Adult; Aged; Anxiety; Depression; Diet; Female; Humans; Male; Melatonin; Menopause; Middle Aged; Obesity; Sleep; Sleep Wake Disorders; Tryptophan

2021
Effects of tryptophan depletion on anxiety, a systematic review.
    Translational psychiatry, 2021, 02-11, Volume: 11, Issue:1

    Topics: Affect; Anxiety; Anxiety Disorders; Double-Blind Method; Humans; Tryptophan

2021
Don't panic. A guide to tryptophan depletion with disorder-specific anxiety provocation.
    Journal of psychopharmacology (Oxford, England), 2016, Volume: 30, Issue:11

    Topics: Anxiety; Anxiety Disorders; Humans; Male; Paroxetine; Serotonin; Tryptophan

2016
Serotonin and brain development.
    International review of neurobiology, 2004, Volume: 59

    Topics: Animals; Anxiety; Autistic Disorder; Brain; Brain Chemistry; Down Syndrome; Humans; Learning; Models, Animal; Mood Disorders; Neuronal Plasticity; Receptors, Serotonin; Schizophrenia; Serotonin; Stress, Physiological; Synapses; Tryptophan

2004
[Influence of physical activity on mental well-being and psychiatric disorders].
    Praxis, 2004, Aug-25, Volume: 93, Issue:35

    Topics: Adolescent; Adult; Aged; Anxiety; beta-Endorphin; Child; Clinical Trials as Topic; Depression; Exercise; Exercise Therapy; Female; Humans; Male; Mental Disorders; Mental Health; Physical Endurance; Serotonin; Socioeconomic Factors; Sports; Time Factors; Tryptophan

2004
The trajectory of biomarkers in symptom management for older adults with cancer.
    Seminars in oncology nursing, 2006, Volume: 22, Issue:1

    Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Aged; Aging; Anxiety; Biomarkers; Biomarkers, Tumor; Cytokines; Dehydroepiandrosterone; Estrogens; Evidence-Based Medicine; Fatigue; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Lymphocytes; Melatonin; Muscle Weakness; Nausea; Neoplasms; Sleep Wake Disorders; Stress, Psychological; T-Lymphocytes; Testosterone; Tryptophan; Vomiting

2006
The eosinophilia-myalgia syndrome--guidelines for patient care.
    The Journal of rheumatology, 1995, Volume: 22, Issue:1

    Topics: Anxiety; Depression; Eosinophilia-Myalgia Syndrome; Glucocorticoids; Heart Diseases; Humans; Lung Diseases; Mental Processes; Neuromuscular Diseases; Practice Guidelines as Topic; Psychotherapy; Skin Diseases; Tryptophan

1995
5-HT and human anxiety. Evidence from studies using acute tryptophan depletion.
    Advances in experimental medicine and biology, 1999, Volume: 467

    Topics: Anxiety; Brain; Female; Humans; Male; Panic Disorder; Reference Values; Serotonin; Sex Characteristics; Tryptophan

1999
Neuroendocrine challenge tests: assessment of 5-HT function in anxiety and depression.
    Molecular aspects of medicine, 1992, Volume: 13, Issue:3

    Topics: Anxiety; Depression; Humans; Neurosecretory Systems; Obsessive-Compulsive Disorder; Panic Disorder; Serotonin; Synapses; Tryptophan

1992
Research report: Institute of Psychiatry Clinical Psychopharmacology Research Team.
    Psychological medicine, 1974, Volume: 4, Issue:1

    Topics: Antidepressive Agents; Anxiety; Barbiturates; Conversion Disorder; Depression; Drug Combinations; Drug Interactions; Electroencephalography; Humans; Hypnotics and Sedatives; Imipramine; Nitrous Oxide; Psychopharmacology; Psychophysiology; Research; Research Design; Sweat Glands; Tranquilizing Agents; Tryptophan

1974

Trials

32 trial(s) available for tryptophan and Anxiety

ArticleYear
No effects of acute tryptophan depletion on anxiety or mood in weight-recovered female patients with anorexia nervosa.
    European archives of psychiatry and clinical neuroscience, 2023, Volume: 273, Issue:1

    Topics: Anorexia Nervosa; Anxiety; Bayes Theorem; Cross-Over Studies; Double-Blind Method; Female; Humans; Serotonin; Tryptophan

2023
Psychological and Sleep Effects of Tryptophan and Magnesium-Enriched Mediterranean Diet in Women with Fibromyalgia.
    International journal of environmental research and public health, 2020, 03-26, Volume: 17, Issue:7

    Topics: Adult; Anxiety; Diet, Mediterranean; Female; Fibromyalgia; Humans; Magnesium; Middle Aged; Sleep; Tryptophan

2020
Effects of tryptophan depletion on selective serotonin reuptake inhibitor-remitted patients with obsessive compulsive disorder.
    Journal of psychopharmacology (Oxford, England), 2017, Volume: 31, Issue:12

    Topics: Adolescent; Adult; Aged; Anxiety; Blood Pressure; Double-Blind Method; Female; Humans; Male; Middle Aged; Obsessive-Compulsive Disorder; Psychiatric Status Rating Scales; Remission Induction; Selective Serotonin Reuptake Inhibitors; Self-Control; Thinking; Tryptophan; Visual Analog Scale; Young Adult

2017
The role of serotonin in the neurocircuitry of negative affective bias: serotonergic modulation of the dorsal medial prefrontal-amygdala 'aversive amplification' circuit.
    NeuroImage, 2013, Volume: 78

    Topics: Adult; Affect; Affective Symptoms; Amygdala; Anxiety; Bias; Cross-Over Studies; Depression; Double-Blind Method; Emotions; Female; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Male; Neural Pathways; Prefrontal Cortex; Serotonin; Serotonin Receptor Agonists; Tryptophan

2013
Effect of sub chronic tryptophan supplementation on stress-induced cortisol and appetite in subjects differing in 5-HTTLPR genotype and trait neuroticism.
    Psychoneuroendocrinology, 2014, Volume: 45

    Topics: Adult; Affect; Anxiety; Anxiety Disorders; Appetite; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Genotype; Humans; Hydrocortisone; Male; Neuroticism; Quantitative Trait, Heritable; Saliva; Serotonin Plasma Membrane Transport Proteins; Stress, Psychological; Test Anxiety Scale; Tryptophan; Young Adult

2014
Fermented milk containing Lactobacillus casei strain Shirota prevents the onset of physical symptoms in medical students under academic examination stress.
    Beneficial microbes, 2016, Volume: 7, Issue:2

    Topics: Animals; Anxiety; Cultured Milk Products; Double-Blind Method; Female; Fermentation; Humans; Lacticaseibacillus casei; Male; Milk; Probiotics; Stress, Physiological; Students, Medical; Tryptophan; Young Adult

2016
Rapid tryptophan depletion following cognitive behavioural therapy for panic disorder.
    Psychopharmacology, 2011, Volume: 213, Issue:2-3

    Topics: Adult; Anxiety; Cognitive Behavioral Therapy; Cross-Over Studies; Double-Blind Method; Female; Flumazenil; GABA Modulators; Humans; Male; Panic Disorder; Psychiatric Status Rating Scales; Tryptophan; Young Adult

2011
Estrogen treatment impairs cognitive performance after psychosocial stress and monoamine depletion in postmenopausal women.
    Menopause (New York, N.Y.), 2010, Volume: 17, Issue:4

    Topics: Affect; Aged; Aged, 80 and over; Anxiety; Cognition Disorders; Double-Blind Method; Estradiol; Estrogens; Female; Follicle Stimulating Hormone; Humans; Hydrocortisone; Mental Recall; Middle Aged; Neuropsychological Tests; Phenylalanine; Postmenopause; Stress, Psychological; Tryptophan; Tyrosine

2010
Influence of acute tryptophan depletion on gastric sensorimotor function in humans.
    American journal of physiology. Gastrointestinal and liver physiology, 2011, Volume: 300, Issue:2

    Topics: Adult; Anxiety; Compliance; Depression; Diagnostic Techniques, Digestive System; Double-Blind Method; Dyspepsia; Eating; Female; Gastric Mucosa; Gastrointestinal Motility; Gastrointestinal Tract; Humans; Intestinal Mucosa; Male; Sensation; Serotonin; Stomach; Time Factors; Tryptophan

2011
The effects of acute tryptophan depletion on costly information sampling: impulsivity or aversive processing?
    Psychopharmacology, 2012, Volume: 219, Issue:2

    Topics: Adult; Amino Acids; Anxiety; Decision Making; Depression; Female; Humans; Impulsive Behavior; Mental Processes; Psychomotor Performance; Self Report; Tryptophan

2012
Acute tryptophan depletion increases translational indices of anxiety but not fear: serotonergic modulation of the bed nucleus of the stria terminalis?
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012, Volume: 37, Issue:8

    Topics: Adult; Anxiety; Double-Blind Method; Fear; Female; Humans; Male; Reflex, Startle; Septal Nuclei; Serotonin; Tryptophan

2012
Depressive and anxiety symptoms in the early puerperium are related to increased degradation of tryptophan into kynurenine, a phenomenon which is related to immune activation.
    Life sciences, 2002, Sep-06, Volume: 71, Issue:16

    Topics: Adult; Anxiety; Depression; Female; Humans; Immunity; Inflammation; Interleukin-6; Interleukin-8; Kynurenine; Leukemia Inhibitory Factor Receptor alpha Subunit; Menstrual Cycle; Postpartum Period; Pregnancy; Psychiatric Status Rating Scales; Receptors, Cytokine; Receptors, OSM-LIF; Tryptophan

2002
Anxiolytic effects of acute tryptophan depletion in anorexia nervosa.
    The International journal of eating disorders, 2003, Volume: 33, Issue:3

    Topics: Adolescent; Adult; Affect; Anorexia Nervosa; Anxiety; Diet; Diet, Reducing; Double-Blind Method; Female; Humans; Tryptophan

2003
Interferon-alpha-induced changes in tryptophan metabolism. relationship to depression and paroxetine treatment.
    Biological psychiatry, 2003, Nov-01, Volume: 54, Issue:9

    Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Anxiety; Depression; Double-Blind Method; Female; Humans; Interferon-alpha; Kynurenine; Male; Melanoma; Middle Aged; Neopterin; Paroxetine; Selective Serotonin Reuptake Inhibitors; Time Factors; Tryptophan

2003
Tryptophan depletion reverses the therapeutic effect of selective serotonin reuptake inhibitors in social anxiety disorder.
    Biological psychiatry, 2004, Oct-01, Volume: 56, Issue:7

    Topics: Adult; Anxiety; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Middle Aged; Phobic Disorders; Selective Serotonin Reuptake Inhibitors; Serotonin; Tryptophan

2004
Serotonin regulation of the human stress response.
    Psychoneuroendocrinology, 2006, Volume: 31, Issue:9

    Topics: Adult; Anxiety; Arousal; Blood Pressure; Carbon Dioxide; Cross-Over Studies; Double-Blind Method; Female; Heart Rate; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Middle Aged; Pituitary-Adrenal System; Prolactin; Reference Values; Serotonin; Stress, Psychological; Tryptophan

2006
Acute tryptophan depletion alters gastrointestinal and anxiety symptoms in irritable bowel syndrome.
    The American journal of gastroenterology, 2006, Volume: 101, Issue:11

    Topics: Adult; Affect; Anxiety; Cross-Over Studies; Double-Blind Method; Female; Gastrointestinal Tract; Humans; Irritable Bowel Syndrome; Male; Serotonin; Tryptophan

2006
Effects of tryptophan depletion on cognitive functioning, obsessive-compulsive symptoms and mood in obsessive-compulsive disorder: preliminary results.
    Neuropsychobiology, 2007, Volume: 56, Issue:2-3

    Topics: Adult; Affect; Anxiety; Cognition; Cross-Over Studies; Depression; Double-Blind Method; Female; Food, Formulated; Humans; Male; Neuropsychological Tests; Obsessive-Compulsive Disorder; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Statistics, Nonparametric; Tryptophan

2007
Effects of tryptophan depletion on responses to yohimbine in healthy human subjects.
    Biological psychiatry, 1995, Jul-15, Volume: 38, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adult; Anxiety; Arousal; Brain; Fear; Female; Humans; Hydrocortisone; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Serotonin; Tryptophan; Yohimbine

1995
The effect of tryptophan depletion and enhancement on subjective and behavioural aggression in normal male subjects.
    Psychopharmacology, 1995, Volume: 118, Issue:1

    Topics: Adult; Affect; Aggression; Amino Acids; Anger; Anxiety; Galvanic Skin Response; Humans; Male; Reaction Time; Tryptophan

1995
Effects of tryptophan depletion on anxiety and on panic provoked by carbon dioxide challenge.
    Psychiatry research, 1998, Feb-27, Volume: 77, Issue:3

    Topics: Adult; Anxiety; Arousal; Carbon Dioxide; Cross-Over Studies; Double-Blind Method; Humans; Male; Panic; Personality Inventory; Serotonin; Tryptophan

1998
Plasma tryptophan and trait aggression.
    Journal of psychopharmacology (Oxford, England), 1999, Volume: 13, Issue:3

    Topics: Adult; Aggression; Anxiety; Depression; Hostility; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Tryptophan

1999
Tryptophan enhancement/depletion and reactions to failure on a cooperative computer game.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1999, Volume: 21, Issue:6

    Topics: Adult; Affect; Aggression; Analysis of Variance; Anger; Anxiety; Blood Pressure; Depression; Double-Blind Method; Emotions; Hostility; Humans; Male; Play and Playthings; Tryptophan

1999
A comparison of the effects of acute tryptophan depletion and acute phenylalanine/tyrosine depletion in healthy women.
    Advances in experimental medicine and biology, 1999, Volume: 467

    Topics: Adult; Affect; Anxiety; Catecholamines; Double-Blind Method; Female; Heart Rate; Humans; Phenylalanine; Stress, Psychological; Tryptophan; Tyrosine

1999
Effects of tryptophan depletion on carbon dioxide provoked panic in panic disorder patients.
    Psychiatry research, 2000, Apr-10, Volume: 93, Issue:3

    Topics: Adult; Agoraphobia; Anxiety; Arousal; Carbon Dioxide; Double-Blind Method; Female; Humans; Male; Middle Aged; Panic; Panic Disorder; Serotonin; Tryptophan

2000
Effects of tryptophan depletion on anxiety induced by simulated public speaking.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2000, Volume: 33, Issue:5

    Topics: Adolescent; Adult; Amino Acids; Anxiety; Dietary Supplements; Female; Heart Rate; Humans; Male; Self-Assessment; Sensitivity and Specificity; Serotonin; Sex Factors; Speech; Test Anxiety Scale; Tryptophan

2000
Behavioural effects of acute tryptophan depletion in healthy male volunteers.
    Journal of psychopharmacology (Oxford, England), 2000, Volume: 14, Issue:2

    Topics: Adult; Affect; Anxiety; Attention; Behavior; Cross-Over Studies; Diet; Double-Blind Method; Emotions; Humans; Male; Memory; Psychiatric Status Rating Scales; Tryptophan

2000
S-tryptophan concentrations after intestinal bypass in extreme obesity.
    Acta medica Scandinavica, 1977, Volume: 201, Issue:4

    Topics: Administration, Oral; Amino Acids; Anxiety; Body Weight; Clinical Trials as Topic; Depression; Humans; Intestine, Small; Jejunum; Liver; Obesity; Placebos; Postoperative Complications; Serum Albumin; Tryptophan; Water-Electrolyte Imbalance

1977
Studies of endocrine activity, plasma tryptophan and catecholamine excretion on psychosurgical patients.
    Acta psychiatrica Scandinavica, 1977, Volume: 56, Issue:1

    Topics: Adult; Anxiety; Clinical Trials as Topic; Depression; Dexamethasone; Epinephrine; Female; Humans; Hydrocortisone; Middle Aged; Norepinephrine; Obsessive-Compulsive Disorder; Personality Inventory; Psychosurgery; Tryptophan

1977
Comparative trial of L-tryptophan and amitriptyline in depressive illness.
    Psychological medicine, 1976, Volume: 6, Issue:4

    Topics: Adult; Aged; Ambulatory Care; Amitriptyline; Antidepressive Agents; Anxiety; Blood Chemical Analysis; Clinical Trials as Topic; Depression; Drug Evaluation; Female; Follow-Up Studies; Hospitalization; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Time Factors; Tryptophan

1976
Potentiation of the antidepressant action of clomipramine by tryptophan.
    Archives of general psychiatry, 1976, Volume: 33, Issue:11

    Topics: Adolescent; Adult; Aged; Anxiety; Clomipramine; Depression; Dibenzazepines; Drug Synergism; Drug Therapy, Combination; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Placebos; Psychomotor Disorders; Time Factors; Tryptophan

1976
Tryptophan and high-carbohydrate diets as adjuncts to smoking cessation therapy.
    Journal of behavioral medicine, 1991, Volume: 14, Issue:2

    Topics: Adolescent; Adult; Anxiety; Behavior Therapy; Combined Modality Therapy; Diet; Dietary Carbohydrates; Humans; Middle Aged; Nicotine; Placebos; Smoking; Smoking Prevention; Substance Withdrawal Syndrome; Tryptophan; Weight Gain

1991

Other Studies

75 other study(ies) available for tryptophan and Anxiety

ArticleYear
Metabolite trajectories across the perinatal period and mental health: A preliminary study of tryptophan-related metabolites, bile acids and microbial composition.
    Behavioural brain research, 2022, 02-10, Volume: 418

    Topics: Adult; Anxiety; Bile Acids and Salts; Chromatography, Liquid; Depression; Dietary Fiber; Fatty Acids, Volatile; Feasibility Studies; Feces; Female; Gastrointestinal Microbiome; Humans; Kynurenic Acid; Kynurenine; Mental Health; Perinatal Care; Pilot Projects; Pregnancy; Tandem Mass Spectrometry; Tryptophan

2022
Tryptophan lessens reserpine induced anxiety, depression and memory impairment by modulating oxidative stress and serotonergic activity.
    Pakistan journal of pharmaceutical sciences, 2021, Volume: 34, Issue:4(Suppleme

    Topics: Acetylcholinesterase; Animals; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, Second-Generation; Anxiety; Depression; Gene Expression Regulation, Enzymologic; Lipid Peroxidation; Memory Disorders; Oxidative Stress; Rats; Reserpine; Stress, Psychological; Tryptophan

2021
Association of plasma tryptophan concentration with periaqueductal gray matter functional connectivity in migraine patients.
    Scientific reports, 2022, 01-14, Volume: 12, Issue:1

    Topics: Anxiety; Case-Control Studies; Depression; Emotions; Female; Humans; Magnetic Resonance Imaging; Male; Migraine Disorders; Pain Perception; Periaqueductal Gray; Synaptic Transmission; Tryptophan

2022
Perspective: Gestational Tryptophan Fluctuation Altering Neuroembryogenesis and Psychosocial Development.
    Cells, 2022, 04-08, Volume: 11, Issue:8

    Topics: Animals; Anxiety; Chickens; Female; Gastrointestinal Microbiome; Humans; Pregnancy; Serotonin; Tryptophan

2022
Tryptophan-rich diet ameliorates chronic unpredictable mild stress induced depression- and anxiety-like behavior in mice: The potential involvement of gut-brain axis.
    Food research international (Ottawa, Ont.), 2022, Volume: 157

    Topics: Animals; Anxiety; Behavior, Animal; Brain-Gut Axis; Depression; Diet; Mice; Serotonin; Stress, Psychological; Tryptophan

2022
Psychological outcomes of COVID-19 survivors at sixth months after diagnose: the role of kynurenine pathway metabolites in depression, anxiety, and stress.
    Journal of neural transmission (Vienna, Austria : 1996), 2022, Volume: 129, Issue:8

    Topics: Anxiety; Biomarkers; COVID-19; Depression; Humans; Kynurenic Acid; Kynurenine; Survivors; Tryptophan

2022
Maternal Stress during Pregnancy in Mice Induces Sex-Dependent Behavioral Alterations in Offspring along with Impaired Serotonin and Kynurenine Pathways of Tryptophan Metabolism.
    Developmental neuroscience, 2022, Volume: 44, Issue:6

    Topics: Animals; Anxiety; Behavior, Animal; Female; Kynurenine; Mice; Pregnancy; Serotonin; Tryptophan

2022
Sex-Dependent Effects of Chronic Restraint Stress on Mood-Related Behaviours and Neurochemistry in Mice.
    International journal of molecular sciences, 2023, Jun-19, Volume: 24, Issue:12

    Topics: Animals; Anxiety; Behavior, Animal; Catecholamines; Depression; Female; Hippocampus; Male; Mice; Mice, Inbred C57BL; Neurochemistry; Prefrontal Cortex; Restraint, Physical; Stress, Psychological; Tryptophan

2023
Liver tryptophan 2,3-dioxygenase: a determinant of anxiety-like behaviour - studies with chronic nicotine administration in rats.
    Behavioural pharmacology, 2023, 09-01, Volume: 34, Issue:6

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Depression; Dioxygenases; Female; Liver; Male; Mice; Nicotine; Rats; Serotonin; Tryptophan; Tryptophan Oxygenase

2023
Anxiety due to Long COVID is partially driven by activation of the tryptophan catabolite (TRYCAT) pathway.
    Asian journal of psychiatry, 2023, Volume: 88

    Topics: Anxiety; COVID-19; Humans; Kynurenine; Post-Acute COVID-19 Syndrome; Tryptophan

2023
γ-[Glu]n-Trp ameliorates anxiety/depression-like behaviors and its anti-inflammatory effect in an animal model of anxiety/depression.
    Food & function, 2019, Sep-01, Volume: 10, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Anxiety; Behavior, Animal; Depression; Disease Models, Animal; Hippocampus; Humans; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Oligopeptides; Prefrontal Cortex; Tryptophan; Tumor Necrosis Factor-alpha; Whey Proteins

2019
Tryptophan alleviates neuroendocrine and behavioral responses to stress in zebrafish.
    Behavioural brain research, 2020, 01-27, Volume: 378

    Topics: Animals; Anxiety; Behavior, Animal; Disease Models, Animal; Female; Fluoxetine; Hydrocortisone; Male; Serotonin Agents; Stress, Psychological; Tryptophan; Zebrafish

2020
Effects of IDO1 and TDO2 inhibition on cognitive deficits and anxiety following LPS-induced neuroinflammation.
    Acta neuropsychiatrica, 2020, Volume: 32, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Brain; Cognitive Dysfunction; Enzyme Inhibitors; Indoles; Inflammation; Kynurenine; Lipopolysaccharides; Male; Mice; Tryptophan

2020
Prenatal IL-6 levels and activation of the tryptophan to kynurenine pathway are associated with depressive but not anxiety symptoms across the perinatal and the post-partum period in a low-risk sample.
    Brain, behavior, and immunity, 2020, Volume: 89

    Topics: Anxiety; Female; Humans; Interleukin-6; Kynurenine; Postpartum Period; Pregnancy; Tryptophan

2020
Identifying a biological signature of prenatal maternal stress.
    JCI insight, 2021, 01-25, Volume: 6, Issue:2

    Topics: Anxiety; Biomarkers; Chemokines; Cohort Studies; Cytokines; Depression; Female; Fetal Development; Humans; Infant, Newborn; Inflammation Mediators; Irritable Bowel Syndrome; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Stress, Psychological; Tryptophan

2021
Association between psychological measures with inflammatory anddisease-related markers of inflammatory bowel disease.
    International journal of psychiatry in clinical practice, 2017, Volume: 21, Issue:3

    Topics: Adult; Aged; Anxiety; Biomarkers; C-Reactive Protein; Case-Control Studies; Colon; Depression; Female; Gene Expression; Humans; Inflammation; Inflammatory Bowel Diseases; Interferon-gamma; Interleukin-1beta; Interleukin-6; Kynurenine; Male; Matrix Metalloproteinase 9; Middle Aged; Quality of Life; Tryptophan

2017
Decreased brain serotonin turnover rate following administration of Sharbat-e-Ahmed Shah produces antidepressant and anxiolytic effect in rats.
    Metabolic brain disease, 2017, Volume: 32, Issue:6

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Brain; Depression; Medicine, Traditional; Motor Activity; Phytotherapy; Plant Extracts; Rats; Serotonin; Swimming; Tryptophan

2017
Metabolic shift induced by systemic activation of T cells in PD-1-deficient mice perturbs brain monoamines and emotional behavior.
    Nature immunology, 2017, Volume: 18, Issue:12

    Topics: Amino Acids; Animals; Anxiety; Behavior, Animal; Brain; Dopamine; Fear; Interferon-gamma; Kynurenine; Lymph Nodes; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Knockout; Programmed Cell Death 1 Receptor; Serotonin; T-Lymphocytes; Tryptophan; Tyrosine

2017
In Schizophrenia, Depression, Anxiety, and Physiosomatic Symptoms Are Strongly Related to Psychotic Symptoms and Excitation, Impairments in Episodic Memory, and Increased Production of Neurotoxic Tryptophan Catabolites: a Multivariate and Machine Learning
    Neurotoxicity research, 2018, Volume: 33, Issue:3

    Topics: Adolescent; Adult; Aged; Anxiety; Depression; Female; Humans; Machine Learning; Male; Medically Unexplained Symptoms; Memory Disorders; Middle Aged; Multivariate Analysis; Psychiatric Status Rating Scales; Thailand; Tryptophan; Young Adult

2018
Comprehensive behavioral analysis of tryptophan 2,3-dioxygenase (Tdo2) knockout mice.
    Neuropsychopharmacology reports, 2018, Volume: 38, Issue:2

    Topics: Animals; Anxiety; Cognition; Hippocampus; Locomotion; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Serotonin; Social Behavior; Tryptophan; Tryptophan Oxygenase

2018
A New Schizophrenia Model: Immune Activation is Associated with the Induction of Different Neurotoxic Products which Together Determine Memory Impairments and Schizophrenia Symptom Dimensions.
    CNS & neurological disorders drug targets, 2019, Volume: 18, Issue:2

    Topics: Anxiety; Anxiety Disorders; Humans; Memory Disorders; Neuropsychological Tests; Schizophrenia; Tryptophan; Xanthurenates

2019
Supervised machine learning to decipher the complex associations between neuro-immune biomarkers and quality of life in schizophrenia.
    Metabolic brain disease, 2019, Volume: 34, Issue:1

    Topics: Adolescent; Adult; Aged; Anxiety; Biomarkers; Case-Control Studies; Depression; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Quality of Life; Schizophrenia; Schizophrenic Psychology; Supervised Machine Learning; Tryptophan; Young Adult

2019
The association between plasma cholesterol and the effect of tryptophan depletion on heart rate variability.
    The Kaohsiung journal of medical sciences, 2019, Volume: 35, Issue:7

    Topics: Adult; Anxiety; Autonomic Nervous System; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Depression; Female; Heart Rate; Humans; Male; Middle Aged; Serotonin; Tryptophan

2019
In vitro structure-activity relationships of aplysinopsin analogs and their in vivo evaluation in the chick anxiety-depression model.
    Bioorganic & medicinal chemistry, 2013, Nov-15, Volume: 21, Issue:22

    Topics: Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Chickens; Depression; Disease Models, Animal; Humans; Monoamine Oxidase; Protein Binding; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Structure-Activity Relationship; Tryptophan

2013
Symptoms of depression and anxiety in anorexia nervosa: links with plasma tryptophan and serotonin metabolism.
    Psychoneuroendocrinology, 2014, Volume: 39

    Topics: Adolescent; Adult; Anorexia Nervosa; Anxiety; Depression; Female; Humans; Male; Nutritional Status; Serotonin; Surveys and Questionnaires; Tryptophan

2014
Gonadal hormone levels and platelet tryptophan and serotonin concentrations in perimenopausal women with or without depressive symptoms.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2014, Volume: 30, Issue:3

    Topics: Anxiety; Blood Platelets; Depression; Depressive Disorder; Diagnostic and Statistical Manual of Mental Disorders; Female; Gonadal Hormones; Hot Flashes; Humans; Mexico; Middle Aged; Perimenopause; Psychiatric Status Rating Scales; Self Report; Serotonin; Severity of Illness Index; Sleep Initiation and Maintenance Disorders; Tryptophan

2014
Experimental Verification of the Effects on Normal Domestic Cats by Feeding Prescription Diet for Decreasing Stress.
    Journal of applied animal welfare science : JAAWS, 2015, Volume: 18, Issue:4

    Topics: Amino Acids; Animal Feed; Animals; Anxiety; Cat Diseases; Cats; Diet; Female; Hydrocortisone; Male; Stress, Psychological; Tryptophan

2015
Western diet-induced anxiolytic effects in mice are associated with alterations in tryptophan metabolism.
    Nutritional neuroscience, 2016, Volume: 19, Issue:8

    Topics: Animals; Anxiety; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cytokines; Diet, Western; Disease Models, Animal; Exploratory Behavior; Gene Expression Regulation, Enzymologic; Indoleamine-Pyrrole 2,3,-Dioxygenase; Intestinal Mucosa; Intestine, Small; Liver; Male; Metabolic Diseases; Mice, 129 Strain; Nerve Tissue Proteins; Neurons; Prosencephalon; Specific Pathogen-Free Organisms; Tryptophan; Tryptophan Hydroxylase

2016
Evidence for serotonin function as a neurochemical difference between fear and anxiety disorders in humans?
    Journal of psychopharmacology (Oxford, England), 2015, Volume: 29, Issue:10

    Topics: Adult; Anxiety; Anxiety Disorders; Fear; Female; Humans; Male; Panic; Selective Serotonin Reuptake Inhibitors; Serotonin; Tryptophan

2015
The role of branched chain amino acid and tryptophan metabolism in rat's behavioral diversity: Intertwined peripheral and brain effects.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2015, Volume: 25, Issue:10

    Topics: Amino Acids, Branched-Chain; Animals; Anxiety; Blood Glucose; Disease Models, Animal; Exploratory Behavior; Insulin; Kynurenine; Large Neutral Amino Acid-Transporter 1; Male; Maze Learning; Plicamycin; Prefrontal Cortex; Protein Synthesis Inhibitors; Random Allocation; Rats, Wistar; RNA, Messenger; Serotonin; Stress, Psychological; Tryptophan

2015
Dietary protein ingested before and during short photoperiods makes an impact on affect-related behaviours and plasma composition of amino acids in mice.
    The British journal of nutrition, 2015, Nov-28, Volume: 114, Issue:10

    Topics: Amino Acids; Animals; Anxiety; Behavior, Animal; Brain Chemistry; Caseins; Depression; Dietary Proteins; Fatty Acids, Nonesterified; Glutens; Lactalbumin; Male; Mice; Mice, Inbred C57BL; Photoperiod; Seasonal Affective Disorder; Serotonin; Soybean Proteins; Swimming; Tryptophan

2015
Milk Collected at Night Induces Sedative and Anxiolytic-Like Effects and Augments Pentobarbital-Induced Sleeping Behavior in Mice.
    Journal of medicinal food, 2015, Volume: 18, Issue:11

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Cattle; Circadian Rhythm; Hypnotics and Sedatives; Male; Maze Learning; Melatonin; Mice, Inbred ICR; Milk; Motor Activity; Pentobarbital; Sleep; Tryptophan

2015
Non-targeted metabolite profiling reveals changes in oxidative stress, tryptophan and lipid metabolisms in fearful dogs.
    Behavioral and brain functions : BBF, 2016, Feb-12, Volume: 12, Issue:1

    Topics: Animals; Anxiety; Biomarkers; Chromatography, Liquid; Dogs; Fear; Lipid Metabolism; Male; Mass Spectrometry; Metabolomics; Oxidative Stress; Pilot Projects; Tryptophan

2016
Indoleamine-2,3-dioxygenase mediates neurobehavioral alterations induced by an intracerebroventricular injection of amyloid-β1-42 peptide in mice.
    Brain, behavior, and immunity, 2016, Volume: 56

    Topics: Amyloid beta-Peptides; Animals; Anxiety; Behavior, Animal; Depression; Disease Models, Animal; Hippocampus; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Injections, Intraventricular; Kynurenine; Memory Disorders; Mice; Nerve Growth Factors; Peptide Fragments; Prefrontal Cortex; Recognition, Psychology; Tryptophan

2016
The Association between Baseline Subjective Anxiety Rating and Changes in Cardiac Autonomic Nervous Activity in Response to Tryptophan Depletion in Healthy Volunteers.
    Medicine, 2016, Volume: 95, Issue:19

    Topics: Adult; Amino Acids; Anxiety; Autonomic Nervous System; Female; Healthy Volunteers; Heart Rate; Humans; Male; Serotonin; Statistics, Nonparametric; Tryptophan; Visual Analog Scale

2016
Female Flinders Sensitive Line rats show estrous cycle-independent depression-like behavior and altered tryptophan metabolism.
    Neuroscience, 2016, 08-04, Volume: 329

    Topics: 5-Hydroxytryptophan; Animals; Anxiety; Brain; Depressive Disorder; Disease Models, Animal; Estrous Cycle; Female; Kynurenine; Male; Motor Activity; ortho-Aminobenzoates; Quinolinic Acid; Rats; Resilience, Psychological; Sex Characteristics; Tryptophan

2016
Maternal gut and fetal brain connection: Increased anxiety and reduced social interactions in Wistar rat offspring following peri-conceptional antibiotic exposure.
    Progress in neuro-psychopharmacology & biological psychiatry, 2016, 11-03, Volume: 71

    Topics: Acoustic Stimulation; Animals; Animals, Newborn; Anti-Infective Agents; Anxiety; Eating; Exploratory Behavior; Female; Homocysteine; Interpersonal Relations; Male; Maze Learning; Pregnancy; Prenatal Exposure Delayed Effects; Prepulse Inhibition; Rats; Rats, Wistar; Sulfathiazoles; Tryptophan

2016
Peripheral Serotonin 1B Receptor Transcription Predicts the Effect of Acute Tryptophan Depletion on Risky Decision-Making.
    The international journal of neuropsychopharmacology, 2017, 01-01, Volume: 20, Issue:1

    Topics: Adult; Anxiety; Decision Making; Double-Blind Method; Female; Gambling; Humans; Male; Neuropsychological Tests; Reaction Time; Receptor, Serotonin, 5-HT1B; RNA, Messenger; Sex Characteristics; Tryptophan

2017
Therapeutic effects of an alpha-casozepine and L-tryptophan supplemented diet on fear and anxiety in the cat.
    Journal of feline medicine and surgery, 2017, Volume: 19, Issue:6

    Topics: Animal Feed; Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Case-Control Studies; Caseins; Cat Diseases; Cats; Diet; Dietary Supplements; Fear; Female; Male; Peptide Fragments; Tryptophan

2017
Tryptophan metabolism, its relation to inflammation and stress markers and association with psychological and cognitive functioning: Tasmanian Chronic Kidney Disease pilot study.
    BMC nephrology, 2016, 11-10, Volume: 17, Issue:1

    Topics: Aged; Aged, 80 and over; Anxiety; Biomarkers; Cognition; Cross-Sectional Studies; Depression; Female; Glomerular Filtration Rate; Humans; Hydrocortisone; Indican; Indoleacetic Acids; Inflammation; Kynurenic Acid; Male; Middle Aged; Neopterin; Oxidative Stress; Pilot Projects; Prospective Studies; Renal Insufficiency, Chronic; Surveys and Questionnaires; Tasmania; Tryptophan

2016
Targeting the Microbiota-Gut-Brain Axis: Prebiotics Have Anxiolytic and Antidepressant-like Effects and Reverse the Impact of Chronic Stress in Mice.
    Biological psychiatry, 2017, Oct-01, Volume: 82, Issue:7

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Brain; Corticosterone; Depression; Disease Models, Animal; Gastrointestinal Microbiome; Gastrointestinal Tract; Gene Expression; Locomotion; Male; Mice; Mice, Inbred C57BL; Neurotransmitter Agents; Nociception; Oligosaccharides; Prebiotics; Stress, Psychological; Tryptophan

2017
Physio-somatic symptoms in schizophrenia: association with depression, anxiety, neurocognitive deficits and the tryptophan catabolite pathway.
    Metabolic brain disease, 2017, Volume: 32, Issue:4

    Topics: Adolescent; Adult; Aged; Anxiety; Cognition Disorders; Depression; Female; Humans; Male; Middle Aged; Schizophrenia; Schizophrenic Psychology; Symptom Assessment; Tryptophan; Young Adult

2017
Influence of chronic mild stress on the behavioural effects of acute tryptophan depletion induced by a gelatin-based mixture.
    Behavioural pharmacology, 2008, Volume: 19, Issue:7

    Topics: Amino Acids; Animals; Anxiety; Appetitive Behavior; Arousal; Behavior, Animal; Body Weight; Depression; Fear; Male; Maze Learning; Mental Recall; Motivation; Pattern Recognition, Visual; Rats; Serotonin; Social Behavior; Stress, Psychological; Taste; Tryptophan

2008
The effects of acute tryptophan depletion on affective behaviour and cognition in Brown Norway and Sprague Dawley rats.
    Journal of psychopharmacology (Oxford, England), 2010, Volume: 24, Issue:4

    Topics: Affect; Animals; Anxiety; Behavior, Animal; Cognition; Depression; Dietary Carbohydrates; Dietary Proteins; Frontal Lobe; Hippocampus; Hydroxyindoleacetic Acid; Interpersonal Relations; Male; Motor Activity; Rats; Rats, Inbred BN; Rats, Sprague-Dawley; Reaction Time; Recognition, Psychology; Serotonin; Species Specificity; Swimming; Tryptophan

2010
Tryptophan 2,3-dioxygenase is a key modulator of physiological neurogenesis and anxiety-related behavior in mice.
    Molecular brain, 2009, Mar-27, Volume: 2

    Topics: Aging; Animals; Anxiety; Behavior, Animal; Cell Proliferation; Cerebral Ventricles; Dentate Gyrus; Gene Deletion; Gene Targeting; Genetic Loci; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Neural Stem Cells; Neurogenesis; Olfactory Bulb; Serotonin; Tryptophan

2009
Repeated administration of Nigella sativa decreases 5-HT turnover and produces anxiolytic effects in rats.
    Pakistan journal of pharmaceutical sciences, 2009, Volume: 22, Issue:2

    Topics: Administration, Oral; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Brain; Disease Models, Animal; Drug Administration Schedule; Exploratory Behavior; Hydroxyindoleacetic Acid; Motor Activity; Plant Oils; Rats; Rats, Wistar; Serotonin; Tryptophan

2009
Decreased immobility in swimming test by homologous interferon-alpha in mice accompanied with increased cerebral tryptophan level and serotonin turnover.
    Neuroscience letters, 2009, Mar-13, Volume: 452, Issue:2

    Topics: Animals; Anxiety; Anxiety Disorders; Brain; Brain Chemistry; Down-Regulation; Exploratory Behavior; Illness Behavior; Interferon-alpha; Male; Mice; Mice, Inbred C57BL; Motor Activity; Movement; Neuropsychological Tests; Serotonin; Tryptophan

2009
Serotonergic function, substance craving, and psychopathology in detoxified alcohol-addicted males undergoing tryptophan depletion.
    Journal of psychiatric research, 2010, Volume: 44, Issue:16

    Topics: Adult; Alcoholism; Amino Acids; Anxiety; Biogenic Monoamines; Humans; Hydroxyindoleacetic Acid; Inactivation, Metabolic; International Classification of Diseases; Male; Middle Aged; Pain Measurement; Polymorphism, Genetic; Promoter Regions, Genetic; Psychiatric Status Rating Scales; Psychopathology; Retrospective Studies; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tryptophan; Young Adult

2010
Chronic gastrointestinal inflammation induces anxiety-like behavior and alters central nervous system biochemistry in mice.
    Gastroenterology, 2010, Volume: 139, Issue:6

    Topics: Animals; Anxiety; Behavior, Animal; Brain-Derived Neurotrophic Factor; Chronic Disease; Colitis; Cytokines; Hippocampus; Kynurenine; Male; Mice; Mice, Inbred AKR; Mice, Inbred BALB C; Proteomics; RNA, Messenger; Trichuriasis; Trichuris; Tryptophan; Vagotomy; Vagus Nerve

2010
Evidence for a key role of the peripheral kynurenine pathway in the modulation of anxiety- and depression-like behaviours in mice: focus on individual differences.
    Pharmacology, biochemistry, and behavior, 2011, Volume: 98, Issue:1

    Topics: Amygdala; Animals; Anxiety; Brain; Depression; Gyrus Cinguli; Kynurenine; Male; Maze Learning; Mice; Mice, Inbred BALB C; Models, Animal; Serotonin; Signal Transduction; Stress, Physiological; Swimming; Tryptophan

2011
Long-lasting effects of inescapable-predator stress on brain tryptophan metabolism and the behavior of juvenile mice.
    Stress (Amsterdam, Netherlands), 2011, Volume: 14, Issue:3

    Topics: Amygdala; Animals; Anxiety; Behavior, Animal; Brain; Hippocampus; Kynurenine; Male; Mice; Mice, Inbred ICR; Prefrontal Cortex; Raphe Nuclei; Rats; Serotonin; Stress, Psychological; Tryptophan

2011
Effects of chronic administration of tryptophan with or without concomitant fluoxetine in depression-related and anxiety-like behaviors on adult rat.
    Neuroscience letters, 2011, Jul-20, Volume: 499, Issue:2

    Topics: Age Factors; Animals; Anxiety; Depression; Drug Therapy, Combination; Fluoxetine; Male; Rats; Rats, Wistar; Tryptophan

2011
Neonatal tryptophan depletion and corticosterone supplementation modify emotional responses in adult male mice.
    Psychoneuroendocrinology, 2013, Volume: 38, Issue:1

    Topics: Anhedonia; Animals; Animals, Newborn; Animals, Suckling; Anxiety; Brain-Derived Neurotrophic Factor; Corpus Striatum; Corticosterone; Dopamine; Emotions; Exploratory Behavior; Female; Hypothalamo-Hypophyseal System; Hypothalamus; Male; Maternal Behavior; Mice; Pituitary-Adrenal System; Serotonin; Tryptophan

2013
Branched-chain amino acids alter neurobehavioral function in rats.
    American journal of physiology. Endocrinology and metabolism, 2013, Feb-15, Volume: 304, Issue:4

    Topics: Amino Acids, Branched-Chain; Animals; Anxiety; Behavior, Animal; Brain; Diet; Diet, High-Fat; Dietary Sucrose; Exploratory Behavior; Kynurenic Acid; Male; Mood Disorders; Neurons; Obesity; Rats; Rats, Wistar; Serotonin; Tryptophan; Weight Gain

2013
Rats subjected to extended L-tryptophan restriction during early postnatal stage exhibit anxious-depressive features and structural changes.
    Journal of neuropathology and experimental neurology, 2006, Volume: 65, Issue:6

    Topics: Age Factors; Animals; Animals, Newborn; Anxiety; Behavior, Animal; Brain; Bromodeoxyuridine; Cell Count; Depression; Diet, Protein-Restricted; Disease Models, Animal; Immunohistochemistry; Male; Maze Learning; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Serotonin; Silver Staining; Swimming; Tryptophan; Tryptophan Hydroxylase

2006
The anxiogenic drug FG-7142 increases serotonin metabolism in the rat medial prefrontal cortex.
    Pharmacology, biochemistry, and behavior, 2006, Volume: 84, Issue:2

    Topics: Animals; Anxiety; Carbolines; Chromatography, High Pressure Liquid; Hydroxyindoleacetic Acid; Male; Prefrontal Cortex; Prosencephalon; Rats; Rats, Wistar; Serotonin; Tryptophan

2006
Low serum tryptophan levels, reduced macrophage IDO activity and high frequency of psychopathology in HCV patients.
    Journal of viral hepatitis, 2006, Volume: 13, Issue:6

    Topics: Adult; Anxiety; Depression; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Macrophages; Male; Middle Aged; Tryptophan

2006
Tryptophan hydroxylase-2 gene variation influences personality traits and disorders related to emotional dysregulation.
    The international journal of neuropsychopharmacology, 2007, Volume: 10, Issue:3

    Topics: Adolescent; Adult; Affective Symptoms; Anxiety; Brain Chemistry; Cohort Studies; Female; Genetic Variation; Genotype; Haplotypes; Humans; Linkage Disequilibrium; Male; Middle Aged; Personality; Personality Disorders; Personality Tests; Psychiatric Status Rating Scales; Reverse Transcriptase Polymerase Chain Reaction; Serotonin; Tryptophan; Tryptophan Hydroxylase

2007
Influence of sex and estrous cycle on the effects of acute tryptophan depletion induced by a gelatin-based mixture in adult Wistar rats.
    Neuroscience, 2007, Jun-29, Volume: 147, Issue:2

    Topics: Amino Acids; Animals; Anxiety; Behavior, Animal; Brain Chemistry; Depression; Estrous Cycle; Female; Gelatin; Interpersonal Relations; Male; Motor Activity; Rats; Rats, Wistar; Reaction Time; Recognition, Psychology; Serotonin; Sex Characteristics; Swimming; Tryptophan

2007
Highly palatable diet consumption increases protein oxidation in rat frontal cortex and anxiety-like behavior.
    Life sciences, 2007, Jun-27, Volume: 81, Issue:3

    Topics: Animals; Anxiety; Behavior, Animal; Body Composition; Diet; Exploratory Behavior; Free Radicals; Glucose Tolerance Test; Lipid Peroxidation; Male; Nerve Tissue Proteins; Oxidative Stress; Prefrontal Cortex; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Sucrose; Thiobarbituric Acid Reactive Substances; Tryptophan

2007
The relationship of alpha and delta EEG frequencies to pain and mood in 'fibrositis' patients treated with chlorpromazine and L-tryptophan.
    Electroencephalography and clinical neurophysiology, 1980, Volume: 50, Issue:1-2

    Topics: Adult; Aged; Alpha Rhythm; Anxiety; Chlorpromazine; Delta Rhythm; Electroencephalography; Emotions; Female; Fibromyalgia; Humans; Male; Middle Aged; Pain; Sleep Stages; Tryptophan

1980
Cerebrospinal fluid amine metabolites, tryptophan and clinical parameters in depression. Part 2. Psychopathological symptoms.
    Journal of affective disorders, 1981, Volume: 3, Issue:2

    Topics: Anxiety; Depressive Disorder; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Phenylacetates; Psychomotor Agitation; Sleep Initiation and Maintenance Disorders; Suicide, Attempted; Tryptophan

1981
Experiences with L-tryptophan in a child and family psychiatric department.
    The Journal of international medical research, 1982, Volume: 10, Issue:3

    Topics: Adolescent; Anxiety; Child; Child Psychiatry; Depression; Female; Humans; Male; Stress, Physiological; Tryptophan

1982
Acute tryptophan depletion in bulimia: effects on large neutral amino acids.
    Biological psychiatry, 1994, Mar-15, Volume: 35, Issue:6

    Topics: Adolescent; Adult; Amino Acids; Anxiety; Bulimia; Drug Combinations; Feeding Behavior; Female; Humans; Male; Serotonin; Tryptophan

1994
Tryptophan and 5-HT in psychiatric illness.
    Advances in experimental medicine and biology, 1996, Volume: 398

    Topics: Anxiety; Brain; Depressive Disorder; Humans; Psychotic Disorders; Reference Values; Serotonin; Tryptophan

1996
Differential effects of social stress on central serotonergic activity and emotional reactivity in Lewis and spontaneously hypertensive rats.
    Neuroscience, 1998, Volume: 82, Issue:1

    Topics: Aggression; Animals; Anxiety; Body Weight; Eating; Emotions; Hypertension; Male; Mesencephalon; Motor Activity; Rats; Rats, Inbred Lew; Rats, Inbred SHR; Receptors, Serotonin; Serotonin; Social Environment; Species Specificity; Stress, Psychological; Tryptophan

1998
Acute antidepressant-like and antianxiety-like effects of tryptophan in mice.
    Pharmacology, 2001, Volume: 62, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Depression; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fenclonine; Male; Melatonin; Mice; Serotonin Antagonists; Tryptophan

2001
[On certain aspects of amino acid metabolism in nervous and mental diseases (tryptophan metabolism)].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2001, Volume: 101, Issue:8

    Topics: Anxiety; Brain; Humans; Immunohistochemistry; Mental Disorders; Tryptophan

2001
Anxiogenic and depressive-like effects, but no cognitive deficits, after repeated moderate tryptophan depletion in the rat.
    Journal of psychopharmacology (Oxford, England), 2002, Volume: 16, Issue:1

    Topics: Animals; Anxiety; Attention; Body Weight; Cerebral Cortex; Cognition; Corticosterone; Depression; Food Preferences; Hippocampus; Male; Memory; Memory, Short-Term; Motor Activity; Rats; Rats, Wistar; Space Perception; Stress, Psychological; Swimming; Taste; Tryptophan

2002
14C-labeled tryptophan uptake and anxiety.
    Biological psychiatry, 1979, Volume: 14, Issue:1

    Topics: Adult; Animals; Anxiety; Carbon Radioisotopes; Chickens; Erythrocytes; Humans; Hydrocortisone; Male; Tryptophan

1979
Effects of tryptophan 2,3-dioxygenase inhibitors in the rat.
    Advances in experimental medicine and biology, 1991, Volume: 294

    Topics: Animals; Anxiety; Brain; Enzyme Inhibitors; Hydroxyindoleacetic Acid; Kynurenine; Liver; Organic Chemicals; Rats; Serotonin; Tryptophan; Tryptophan Oxygenase

1991
L-tryptophan supplementation does not affect postoperative pain intensity or consumption of analgesics.
    Pain, 1991, Volume: 44, Issue:3

    Topics: Adolescent; Adult; Affect; Analgesics; Anxiety; Female; Follow-Up Studies; Humans; Male; Middle Aged; Pain, Postoperative; Personality; Preoperative Care; Surgery, Oral; Surveys and Questionnaires; Tryptophan

1991
Tryptophan intake and national character.
    Perceptual and motor skills, 1989, Volume: 69, Issue:3 Pt 1

    Topics: Anxiety; Cross-Cultural Comparison; Extraversion, Psychological; Humans; Risk Factors; Suicide; Tryptophan

1989
Biochemistry of nervous dogs.
    The Pavlovian journal of biological science, 1974, Volume: 9, Issue:3

    Topics: Acetylcholinesterase; Age Factors; Animals; Anxiety; Behavior, Animal; Blood Proteins; Catechol O-Methyltransferase; Cerebrospinal Fluid Proteins; Chlorides; Cholesterol; Creatine Kinase; Dogs; Fructose-Bisphosphate Aldolase; Hematocrit; Hemoglobins; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; L-Lactate Dehydrogenase; Lactates; Leukocyte Count; Potassium; Sodium; Species Specificity; Stress, Physiological; Stress, Psychological; Tranylcypromine; Tryptophan

1974
Electrophysiological studies on the brain. Effects of nucleotide and tryptophan metabolites as modified by polyamines in normal and psychotic subjects.
    Diseases of the nervous system, 1970, Volume: 31, Issue:11

    Topics: Amines; Anxiety; Brain; Capillary Permeability; Electrophysiology; Feedback; Humans; Neurotic Disorders; Nucleoproteins; Nucleotides; Psychotic Disorders; Schizophrenia; Tranquilizing Agents; Tryptophan

1970