tryptophan and Allergic Encephalomyelitis

tryptophan has been researched along with Allergic Encephalomyelitis in 56 studies

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-199037 (66.07)18.7374
1990's1 (1.79)18.2507
2000's6 (10.71)29.6817
2010's7 (12.50)24.3611
2020's5 (8.93)2.80

Authors

AuthorsStudies
Ejtemaei-Mehr, S; Ghahremani, MH; Ghanbari, A; Ghazi-Khansari, M; Guillemin, GJ; Jand, Y1
Ashida, H; Harada, Y; Kanai, T; Koda, Y; Melhem, H; Mikami, Y; Miyamoto, K; Nemoto, Y; Niess, JH; Okamoto, R; Sato, T; Sujino, T; Suzuki, S; Suzuki, T; Tanaka, KF; Teratani, T; Tomura, M; Yonemoto, Y; Yoshimatsu, Y; Yoshimura, A1
Bharti, R; Bode, HB; Brandao, I; Deumelandt, K; Epping, L; Falk-Paulsen, M; Grill, A; Keil, M; Kramer, M; Kurschus, FC; Lanz, TV; Meuth, SG; Mishra, N; Mohapatra, SR; Niesler, B; Oezen, I; Okun, JG; Opitz, CA; Platten, M; Rehman, A; Reinhardt, C; Rosenstiel, P; Röth, R; Röwe, J; Sanghvi, K; Sonner, JK; Tang, Y; von Landenberg, A; Wanke, F; Wick, W; Wolf, L; Wolff, H1
Albini, E; Annunziato, L; Belladonna, ML; Bianchi, R; Boscia, F; Calabresi, P; Carvalho, A; Coletti, A; Cunha, C; Di Filippo, M; Fallarino, F; Gaetani, L; Gargaro, M; Greco, FA; Grohmann, U; Iacono, A; Iamandii, IM; Macchiarulo, A; Maciel, P; Manni, G; Matino, D; Mondanelli, G; Orabona, C; Pallotta, MT; Panfili, E; Peppelenbosch, M; Proietti, E; Puccetti, P; Santambrogio, L; Vacca, C; Volpi, C1
Boeira, SP; Cattelan Souza, L; Giacomeli, R; Jesse, CR; Prigol, M; Silva, MRP; Zarzecki, MS1
Hasan, M; Jung, BH; Kwon, OS; Lee, G; Lee, SH; Seo, JE1
Becker, S; Lanz, TV; Mohapatra, SR; Opitz, CA; Platten, M; Wick, W1
Alm, EJ; Balogh, A; Bartolomaeus, H; Basic, M; Bork, P; Boschmann, M; Côrte-Real, BF; Costea, PI; Dechend, R; Forslund, K; Frätzer, C; Gerlach, RG; Gollasch, M; Grohme, DA; Haase, S; Jantsch, J; Kearney, SM; Kempa, S; Kleiner, FH; Kleinewietfeld, M; Klug, L; Krannich, A; Linker, RA; Mähler, A; Maier, L; Markó, L; Matus, MG; Müller, DN; Neubert, P; Olesen, SW; Rakova, N; Schatz, V; Sunagawa, S; Titze, JM; Tsvetkov, D; Typas, A; Vvedenskaya, O; Wilck, N; Wu, C1
Alvarez, JI; Antel, J; Ardura-Fabregat, A; Blain, M; Borio, M; Borucki, DM; Chao, CC; de Lima, KA; Dragin, LL; Gutiérrez-Vázquez, C; Healy, L; Hewson, P; Laplaud, DA; Neziraj, T; Prinz, M; Quintana, FJ; Rothhammer, V; Staszewski, O; Takenaka, MC; Tjon, EC; Wheeler, M1
Alvarez, JI; Anandasabapathy, N; Antel, J; Blain, M; Bunse, L; Chao, CC; Clish, CB; Izquierdo, G; Jung, S; Kébir, H; Kenison, JE; Mascanfroni, ID; Mayo, L; Obholzer, N; Patel, B; Pochet, N; Prat, A; Prinz, M; Quintana, FJ; Rothhammer, V; Takenaka, MC; Yan, R1
Cullimore, ML; Fallarino, F; Gran, B; Li, H; Rostami, A; Xu, H; Yan, Y; Yu, S; Zhang, GX1
Ahonen, C; Bennett, KA; de Vries, VC; Ha, DG; Le Mercier, I; Noelle, RJ; Nowak, EC; Wasiuk, A1
Sakurai, K; Shearer, GM; Tschetter, JR; Ward, JM; Zou, JP1
WOLFGRAM, F1
Butovsky, O; Hauben, E; Ibarra, A; Schwartz, M1
Bechmann, I; Bunse, J; Kovac, AD; Kwidzinski, E; Nitsch, R; Ullrich, O; Zipp, F1
Link, H; Liu, X; Xiao, BG1
Fontoura, P; Garren, H; Gupta, R; Ho, PP; Hur, EM; Kidd, BA; Lee, LY; Platten, M; Robinson, WH; Selley, ML; Sobel, RA; Steinman, L; Youssef, S1
Bechmann, I; Kwidzinski, E1
Montgomery, IN; Rauch, HC; Swanborg, RH1
Honegger, CG; Isler, H1
McRae, BL; Miller, SD1
Spitler, LE; von Muller, CM; Young, JD1
Swanborg, RH3
Bernard, CC; Lamoureux, G1
Jollès, P; Migliore-Samour, D; Thompson, M; Westall, FC1
Carvalho, EF; Hashim, GA; Sharpe, RD; Stevens, LE1
Alvord, EC; Driscoll, BF; Kies, MW1
Arnon, R; Herz, A; Sela, M; Teitelbaum, D; Webb, C1
Thompson, M; Westall, FC1
Westall, FC2
Eylar, EH2
Cammisuli, S; Feurer, C; Honegger, CG; Krenger, W1
Khizhniak, MG; Zhitnukhin, IuL1
Carnegie, PR1
Caccam, J; Jackson, J; Robinson, AB; Westall, FC; Ylar, EH1
Carnegie, PR; Lennon, VA; Wilks, AV1
Brostoff, S; Eylar, EH; Westall, FC1
Burnett, PR; Eylar, EH1
Amesse, LS; Swanborg, RH1
Lycke, E; Roos, BE1
Saieg, RG; Swanborg, RH; Swierkosz, JE1
Cyr, R; Geier, M; Geier, S; Thompson, M; Tsuchiya, D; Ward, E; Westall, FC; Young, JD; Yurochko, F1
Eylar, EH; Hashim, GA1
Crawford, M; Feldmann, M; Lennon, V1
Chao, LP; Csejtey, J; Einstein, ER; Kibler, RF1
Eylar, EH; Thompson, M1
Chao, LP; Csejtey, J; Einstein, ER1
Eylar, EH; Oshiro, Y1
Caccam, J; Eylar, EH; Jackson, JJ; Robinson, AB; Westall, FC1
Chao, LP; Einstein, ER1
Bergstrand, H1

Reviews

1 review(s) available for tryptophan and Allergic Encephalomyelitis

ArticleYear
IDO expression in the brain: a double-edged sword.
    Journal of molecular medicine (Berlin, Germany), 2007, Volume: 85, Issue:12

    Topics: Animals; Brain; Candidiasis; Cytomegalovirus Infections; Encephalomyelitis, Autoimmune, Experimental; HIV Infections; Humans; Immune Tolerance; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Multiple Sclerosis; Neurons; Tryptophan

2007

Other Studies

55 other study(ies) available for tryptophan and Allergic Encephalomyelitis

ArticleYear
Melatonin ameliorates disease severity in a mouse model of multiple sclerosis by modulating the kynurenine pathway.
    Scientific reports, 2022, 09-24, Volume: 12, Issue:1

    Topics: Animals; Biological Factors; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Melatonin; Mice; Mice, Inbred C57BL; Multiple Sclerosis; NAD; Nicotinamide N-Methyltransferase; Receptors, Aryl Hydrocarbon; RNA, Messenger; Severity of Illness Index; Tryptophan

2022
The gut microbiota-induced kynurenic acid recruits GPR35-positive macrophages to promote experimental encephalitis.
    Cell reports, 2023, 08-29, Volume: 42, Issue:8

    Topics: Animals; Encephalitis; Encephalomyelitis, Autoimmune, Experimental; Gastrointestinal Microbiome; Kynurenic Acid; Macrophages; Tryptophan

2023
Dietary tryptophan links encephalogenicity of autoreactive T cells with gut microbial ecology.
    Nature communications, 2019, 10-25, Volume: 10, Issue:1

    Topics: Animals; Autoimmunity; Diet; Dietary Proteins; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Gastrointestinal Microbiome; Mice; Multiple Sclerosis; RNA, Ribosomal, 16S; T-Lymphocytes; Tryptophan

2019
Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 02-18, Volume: 117, Issue:7

    Topics: Allosteric Regulation; Allosteric Site; Animals; Biocatalysis; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Leukocytes, Mononuclear; Male; Mice, Knockout; Multiple Sclerosis; Serotonin; Tryptophan

2020
Involvement of Indoleamine-2,3-Dioxygenase and Kynurenine Pathway in Experimental Autoimmune Encephalomyelitis in Mice.
    Neurochemical research, 2020, Volume: 45, Issue:12

    Topics: Animals; Body Weight; Cytokines; Encephalomyelitis, Autoimmune, Experimental; Enzyme Inhibitors; Female; Gene Expression; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenine; Kynurenine 3-Monooxygenase; Mice, Inbred C57BL; Myelin-Oligodendrocyte Glycoprotein; Oximes; Peptide Fragments; Quinolinic Acid; Sulfonamides; Tryptophan

2020
Employing metabolomic approaches to determine the influence of age on experimental autoimmune encephalomyelitis (EAE).
    Molecular immunology, 2021, Volume: 135

    Topics: Age Factors; Aging; Animals; Autoimmunity; Brain; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Fatty Acids, Unsaturated; Female; Interleukin-6; Metabolome; Metabolomics; Mice; Mice, Inbred C57BL; NADPH Oxidases; Risk Factors; Sphingolipids; Spinal Cord; Tryptophan; Tyrosine

2021
Suppression of Th1 differentiation by tryptophan supplementation in vivo.
    Amino acids, 2017, Volume: 49, Issue:7

    Topics: Animals; Dietary Supplements; Encephalomyelitis, Autoimmune, Experimental; Female; Immune Tolerance; Mice; Multiple Sclerosis; Th1 Cells; Tryptophan

2017
Salt-responsive gut commensal modulates T
    Nature, 2017, 11-30, Volume: 551, Issue:7682

    Topics: Animals; Autoimmunity; Blood Pressure; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Feces; Gastrointestinal Microbiome; Humans; Hypertension; Indoleacetic Acids; Indoles; Intestines; Lactobacillus; Lymphocyte Activation; Lymphocyte Count; Male; Mice; Pilot Projects; Sodium Chloride; Symbiosis; Th17 Cells; Tryptophan

2017
Microglial control of astrocytes in response to microbial metabolites.
    Nature, 2018, Volume: 557, Issue:7707

    Topics: Animals; Astrocytes; Cells, Cultured; Central Nervous System; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; ErbB Receptors; Female; Humans; Inflammation; Lipopolysaccharide Receptors; Mice; Mice, Inbred C57BL; Microglia; Multiple Sclerosis; Receptors, Aryl Hydrocarbon; Symbiosis; Transforming Growth Factor alpha; Tryptophan; Vascular Endothelial Growth Factor B; Vascular Endothelial Growth Factor Receptor-1

2018
Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor.
    Nature medicine, 2016, Volume: 22, Issue:6

    Topics: Animals; Astrocytes; Case-Control Studies; Cell Proliferation; Central Nervous System; Chemokine CCL2; Chromatin Immunoprecipitation; Chromatography, High Pressure Liquid; Encephalomyelitis, Autoimmune, Experimental; Fluorescent Antibody Technique; Gastrointestinal Microbiome; Gene Expression Profiling; Gene Knockdown Techniques; Glial Fibrillary Acidic Protein; Humans; Immunoblotting; Indican; Indoles; Inflammation; Interferon Type I; Interferon-beta; Limosilactobacillus reuteri; Mice; Mice, Knockout; Multiple Sclerosis; Myxovirus Resistance Proteins; Nitric Oxide Synthase Type II; Optical Imaging; Polymerase Chain Reaction; Receptor, Interferon alpha-beta; Receptors, Aryl Hydrocarbon; Serotonin; STAT1 Transcription Factor; Suppressor of Cytokine Signaling Proteins; T-Lymphocytes; Tryptophan; Tryptophanase

2016
IDO upregulates regulatory T cells via tryptophan catabolite and suppresses encephalitogenic T cell responses in experimental autoimmune encephalomyelitis.
    Journal of immunology (Baltimore, Md. : 1950), 2010, Nov-15, Volume: 185, Issue:10

    Topics: Animals; Cell Differentiation; Cell Separation; Coculture Techniques; Cytokines; Dendritic Cells; Encephalomyelitis, Autoimmune, Experimental; Flow Cytometry; Indoleamine-Pyrrole 2,3,-Dioxygenase; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Knockout; T-Lymphocyte Subsets; T-Lymphocytes, Regulatory; Th1 Cells; Th17 Cells; Tryptophan

2010
Tryptophan hydroxylase-1 regulates immune tolerance and inflammation.
    The Journal of experimental medicine, 2012, Oct-22, Volume: 209, Issue:11

    Topics: Animals; CD4-Positive T-Lymphocytes; Cell Line, Tumor; Cells, Cultured; Encephalomyelitis, Autoimmune, Experimental; Female; Flow Cytometry; Gene Expression; Immune Tolerance; Inflammation; Male; Mast Cells; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Neoplasms, Experimental; Reverse Transcriptase Polymerase Chain Reaction; Skin Transplantation; TOR Serine-Threonine Kinases; Transplantation, Homologous; Tryptophan; Tryptophan Hydroxylase

2012
Effect of indoleamine 2,3-dioxygenase on induction of experimental autoimmune encephalomyelitis.
    Journal of neuroimmunology, 2002, Volume: 129, Issue:1-2

    Topics: Animals; Axons; Cell Division; Cytokines; Disease Models, Animal; Disease Progression; Encephalomyelitis, Autoimmune, Experimental; Female; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Interleukin-10; Interleukin-4; Kinetics; Kynurenine; Lymph Nodes; Mice; RNA, Messenger; Spinal Cord; T-Lymphocytes; Treatment Outcome; Tryptophan; Tryptophan Oxygenase

2002
MACROMOLECULAR CONSTITUENTS OF MYELIN.
    Annals of the New York Academy of Sciences, 1965, Mar-31, Volume: 122

    Topics: Amino Acids; Animals; Antigens; Electrophoresis; Encephalomyelitis; Encephalomyelitis, Autoimmune, Experimental; Guinea Pigs; Lipoproteins; Macromolecular Substances; Myelin Sheath; Neurochemistry; Polysaccharides; Research; Trypsin; Tryptophan

1965
The therapeutic window after spinal cord injury can accommodate T cell-based vaccination and methylprednisolone in rats.
    The European journal of neuroscience, 2004, Volume: 19, Issue:11

    Topics: Analysis of Variance; Animals; Behavior, Animal; Cell Count; Cell Division; Cells, Cultured; Dextrans; Ectodysplasins; Encephalomyelitis, Autoimmune, Experimental; Female; Immunohistochemistry; Immunotherapy, Active; Laminectomy; Membrane Proteins; Methylprednisolone; Motor Activity; Mycobacterium; Myelin Basic Protein; Neuroprotective Agents; Peptide Fragments; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Rhodamines; Species Specificity; Spinal Cord Injuries; T-Lymphocytes; Time Factors; Tryptophan

2004
IDO (indolamine 2,3-dioxygenase) expression and function in the CNS.
    Advances in experimental medicine and biology, 2003, Volume: 527

    Topics: Animals; Astrocytes; Central Nervous System; Encephalomyelitis, Autoimmune, Experimental; Gene Expression; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Mice; Microglia; Recombinant Proteins; RNA, Messenger; Tryptophan; Tryptophan Oxygenase

2003
Antigen-specific T cell functions are suppressed over the estrogen-dendritic cell-indoleamine 2,3-dioxygenase axis.
    Steroids, 2004, Volume: 69, Issue:10

    Topics: Animals; Antigen Presentation; Apoptosis; Cell Proliferation; Dendritic Cells; Encephalomyelitis, Autoimmune, Experimental; Enzyme Inhibitors; Estrogens; Female; Gene Expression; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Interleukin-10; Lymph Nodes; Lymphocyte Activation; Myelin Basic Protein; Peptide Fragments; Rats; Rats, Inbred Lew; RNA, Messenger; T-Lymphocytes; Tryptophan; Tryptophan Oxygenase; Vaccination

2004
Treatment of autoimmune neuroinflammation with a synthetic tryptophan metabolite.
    Science (New York, N.Y.), 2005, Nov-04, Volume: 310, Issue:5749

    Topics: Adoptive Transfer; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigen-Presenting Cells; Brain; Cell Line; Cytokines; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Histocompatibility Antigens Class II; Immune Tolerance; Immunosuppressive Agents; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Lymphocyte Activation; Mice; Mice, Transgenic; Microglia; Multiple Sclerosis; Myelin Proteins; ortho-Aminobenzoates; Signal Transduction; Spinal Cord; T-Lymphocytes; Th1 Cells; Th2 Cells; Tryptophan

2005
Inhibition of experimental allergic encephalomyelitis by carrier administered prior to challenge with encephalitogenic peptide-carrier conjugate.
    European journal of immunology, 1981, Volume: 11, Issue:4

    Topics: Animals; Carrier Proteins; Cattle; Encephalomyelitis, Autoimmune, Experimental; Guinea Pigs; Myelin Basic Protein; Peptides; Serum Albumin, Bovine; Tryptophan

1981
Neurotransmitters, precursors and metabolites in spinal cord and brain of Lewis rats with EAE.
    Progress in clinical and biological research, 1984, Volume: 146

    Topics: Animals; Brain; Dopamine; Encephalomyelitis, Autoimmune, Experimental; Epinephrine; Homovanillic Acid; Hydroxyindoleacetic Acid; Neurotransmitter Agents; Norepinephrine; Rats; Rats, Inbred Lew; Serotonin; Spinal Cord; Tryptophan; Tyrosine

1984
Fine specificity of CD4+ T cell responses to the dominant encephalitogenic PLP 139-151 peptide in SJL/J mice.
    Neurochemical research, 1994, Volume: 19, Issue:8

    Topics: Animals; Antibody Formation; Antibody Specificity; CD4-Positive T-Lymphocytes; Cell Division; Encephalomyelitis, Autoimmune, Experimental; Epitopes; Female; Mice; Mice, Inbred Strains; Myelin Proteins; Myelin Proteolipid Protein; Peptide Fragments; Tryptophan

1994
Experimental allergic encephalitis: study of cellular immunity to the encephalitogenic determinant.
    Cellular immunology, 1975, Volume: 15, Issue:1

    Topics: Animals; Cattle; Cell Migration Inhibition; Cells, Cultured; Chromatography, Gel; DNA; Encephalomyelitis, Autoimmune, Experimental; Epitopes; Freund's Adjuvant; gamma-Globulins; Guinea Pigs; Hemocyanins; Humans; Immunity, Cellular; Immunization; Lymphocyte Activation; Lymphocytes; Macrophages; Myelin Basic Protein; Peptides; Skin Tests; Tryptophan

1975
Antigen-induced inhibition of experimental allergic encephalomyelitis. III. Localization of an inhibitory site distinct from the major encephalitogenic determinant of myelin basic protein.
    Journal of immunology (Baltimore, Md. : 1950), 1975, Volume: 114, Issue:1 Pt 1

    Topics: Amino Acid Sequence; Animals; Antigens; Brain; Electrophoresis, Polyacrylamide Gel; Encephalomyelitis, Autoimmune, Experimental; Guinea Pigs; Mycobacterium; Myelin Basic Protein; Pepsin A; Peptides; Tryptophan

1975
Inhibition by serum of encephalitogenic activity of myelin basic protein.
    International archives of allergy and applied immunology, 1975, Volume: 48, Issue:5

    Topics: Animals; Antibodies; Arthus Reaction; Blood; Cattle; Complement Fixation Tests; Encephalomyelitis, Autoimmune, Experimental; Epitopes; Female; Fetus; Guinea Pigs; Horses; Hot Temperature; Humans; Hypersensitivity, Delayed; Immunodiffusion; Myelin Basic Protein; Myelin Sheath; Passive Cutaneous Anaphylaxis; Rabbits; Radioimmunoassay; Rats; Sheep; Skin Tests; Species Specificity; Tryptophan

1975
Induction of allergic encephalomyelitis using hydrosoluble adjuvant and the tryptophan region of myelin basic protein.
    Immunological communications, 1975, Volume: 4, Issue:4

    Topics: Adjuvants, Immunologic; Animals; Brain; Encephalomyelitis, Autoimmune, Experimental; Female; Guinea Pigs; Injections, Intradermal; Mycobacterium tuberculosis; Myelin Basic Protein; Peptide Biosynthesis; Peptides; Spinal Cord; Tryptophan

1975
Suppression and reversal of allergic encephalomyelitis in guinea pigs with a non-encephalitogenic analogue of the tryptophan region of the myelin basic protein.
    Journal of immunology (Baltimore, Md. : 1950), 1976, Volume: 116, Issue:1

    Topics: Animals; Encephalomyelitis, Autoimmune, Experimental; Epitopes; Hypersensitivity, Delayed; Immunosuppressive Agents; Mice; Myelin Basic Protein; Peptides; Tryptophan

1976
Protection against experimental allergic encephalomyelitis with peptides derived from myelin basic protein: presence of intact encephalitogenic site is essential.
    Journal of immunology (Baltimore, Md. : 1950), 1976, Volume: 117, Issue:1

    Topics: Animals; Encephalomyelitis, Autoimmune, Experimental; Guinea Pigs; Immunization; Myelin Basic Protein; Peptides; Rats; Species Specificity; Tryptophan

1976
Molecular requirements involved in suppression of EAE by synthetic basic copolymers of amino acids.
    Immunochemistry, 1976, Volume: 13, Issue:4

    Topics: Amino Acids; Animals; Antigens; Cross Reactions; Encephalomyelitis, Autoimmune, Experimental; Guinea Pigs; Immunosuppressive Agents; Lymphocyte Activation; Myelin Basic Protein; Polymers; Skin Tests; Tryptophan

1976
Further definition of the encephalitogenic region for guinea pigs.
    Immunological communications, 1977, Volume: 6, Issue:1

    Topics: Amino Acid Sequence; Animals; Encephalomyelitis, Autoimmune, Experimental; Glutamine; Guinea Pigs; Myelin Basic Protein; Peptide Fragments; Tryptophan

1977
High dose inhibition of the tryptophan peptide induced encephalitogenicity.
    Immunological communications, 1978, Volume: 7, Issue:1

    Topics: Animals; Dose-Response Relationship, Immunologic; Encephalomyelitis, Autoimmune, Experimental; Female; Freund's Adjuvant; Guinea Pigs; Mycobacterium tuberculosis; Myelin Basic Protein; Peptides; Protein Conformation; Tryptophan

1978
Peptides and autoimmune disease.
    Advances in experimental medicine and biology, 1978, Volume: 98

    Topics: Amino Acid Sequence; Animals; Encephalomyelitis, Autoimmune, Experimental; Epitopes; Haplorhini; Macaca mulatta; Mice; Myelin Basic Protein; Oligopeptides; Peptide Fragments; Rabbits; Rats; Species Specificity; Tryptophan

1978
Changes of neurotransmitter systems in chronic relapsing experimental allergic encephalomyelitis in rat brain and spinal cord.
    Journal of neurochemistry, 1986, Volume: 47, Issue:4

    Topics: Animals; Brain; Chronic Disease; Dopamine; Encephalomyelitis, Autoimmune, Experimental; Female; Hydroxyindoleacetic Acid; Neurotransmitter Agents; Norepinephrine; Rats; Recurrence; Serotonin; Spinal Cord; Tissue Distribution; Tryptophan; Tyrosine

1986
[Immunomorphologic features of experimental allergic encephalomyelitis induced by the administration of tryptophan peptide].
    Biulleten' eksperimental'noi biologii i meditsiny, 1989, Volume: 108, Issue:8

    Topics: Animals; Brain; Demyelinating Diseases; Encephalomyelitis, Autoimmune, Experimental; Guinea Pigs; Hypersensitivity, Delayed; Myelin Basic Protein; Peptides; Spinal Cord; Tryptophan

1989
The effect of selective modification of tryptophan, lysine and arginine residues of basic brain protein on encephalitogenic activity.
    Journal of immunology (Baltimore, Md. : 1950), 1970, Volume: 105, Issue:4

    Topics: Anhydrides; Animals; Antigens; Arginine; Brain; Brain Chemistry; Butanones; Cattle; Cellulose; Electrophoresis; Encephalomyelitis, Autoimmune, Experimental; Epitopes; Glycols; Lysine; Nerve Tissue Proteins; Nitrobenzenes; Nitrophenols; Spectrophotometry; Tryptophan

1970
Properties, structure and possible neuroreceptor role of the encephalitogenic protein of human brain.
    Nature, 1971, Jan-01, Volume: 229, Issue:5279

    Topics: Amino Acid Sequence; Binding Sites; Brain Chemistry; Encephalomyelitis, Autoimmune, Experimental; Epitopes; Humans; Models, Structural; Nerve Tissue Proteins; Receptors, Drug; Serotonin; Tryptophan

1971
Essential chemical requirements for induction of allergic encephalomyelitis.
    Nature, 1971, Jan-01, Volume: 229, Issue:5279

    Topics: Amino Acid Sequence; Animals; Binding Sites; Biological Assay; Encephalomyelitis, Autoimmune, Experimental; Epitopes; Glutamine; Guinea Pigs; Hypersensitivity, Delayed; Lysine; Models, Structural; Nerve Tissue Proteins; Peptides; Tryptophan

1971
Immunologic properties of the main encephalitogenic peptide from the basic protein of human myelin.
    Journal of immunology (Baltimore, Md. : 1950), 1970, Volume: 105, Issue:5

    Topics: Amino Acid Sequence; Animals; Antibody Formation; Antigen-Antibody Reactions; Antigens; Ascitic Fluid; Autoimmune Diseases; Brain Chemistry; Cell Movement; Encephalomyelitis, Autoimmune, Experimental; Epitopes; Female; Guinea Pigs; Humans; Hypersensitivity, Delayed; Iodine Isotopes; Macrophages; Male; Myelin Sheath; Pepsin A; Peptides; Proteins; Radioimmunoassay; Skin Tests; Tryptophan

1970
Allergic encephalomyelitis. An encephalitogenic peptide derived from the basic protein of myelin.
    The Journal of biological chemistry, 1971, May-25, Volume: 246, Issue:10

    Topics: Amino Acid Sequence; Animals; Antibodies; Cattle; Chromatography, Gel; Electrophoresis; Encephalomyelitis, Autoimmune, Experimental; Epitopes; Guinea Pigs; Haplorhini; Hemagglutination Inhibition Tests; Myelin Sheath; Nerve Tissue Proteins; Pepsin A; Peptides; Phenylalanine; Rabbits; Spinal Cord; Thiocyanates; Trypsin; Tryptophan

1971
Allergic encephalomyelitis. Oxidation and cleavage of the single tryptophan residue of the A1 protein from bovine and human myelin.
    The Journal of biological chemistry, 1971, May-25, Volume: 246, Issue:10

    Topics: Amino Acids; Animals; Brain; Bromine; Cattle; Chromatography, Gel; Electrophoresis; Encephalomyelitis, Autoimmune, Experimental; Epitopes; Fluorescence; Guinea Pigs; Hemagglutination Inhibition Tests; Humans; Hypersensitivity, Delayed; Myelin Sheath; Nerve Tissue Proteins; Nitrobenzenes; Oxidation-Reduction; Peptides; Sheep; Skatole; Spectrophotometry; Spinal Cord; Sulfenic Acids; Tryptophan; Ultraviolet Rays

1971
Experimental allergic encephalomyelitis: species variability of the encephalitogenic determinant.
    Journal of immunology (Baltimore, Md. : 1950), 1971, Volume: 107, Issue:1

    Topics: Animals; Antigens; Brain; Bromides; Cattle; Electrophoresis, Disc; Encephalomyelitis, Autoimmune, Experimental; Epitopes; Freund's Adjuvant; Male; Nerve Tissue Proteins; Rats; Species Specificity; Spinal Cord; Tryptophan

1971
Brain monoamines in guinea pigs with experimental allergic encephalitis.
    International archives of allergy and applied immunology, 1973, Volume: 45, Issue:3

    Topics: Animals; Antibodies; Brain Chemistry; Complement Fixation Tests; Dopamine; Encephalomyelitis, Autoimmune, Experimental; Fenclonine; Guinea Pigs; Homovanillic Acid; Hydroxyindoleacetic Acid; Lysergic Acid Diethylamide; Myelin Basic Protein; Norepinephrine; Serotonin; Spinal Cord; Tryptophan

1973
Studies on the species-variability of experimental allergic encephalomyelitis in guinea pigs and rats.
    Journal of immunology (Baltimore, Md. : 1950), 1974, Volume: 112, Issue:2

    Topics: Animals; Brain; Cattle; Cyanogen Bromide; Electrophoresis, Polyacrylamide Gel; Encephalomyelitis, Autoimmune, Experimental; Epitopes; Guinea Pigs; Molecular Weight; Myelin Basic Protein; Rats; Rats, Inbred Lew; Species Specificity; Spectrophotometry; Spinal Cord; Tryptophan

1974
Experimental allergic encephalomyelitis (EAE).
    Neurosciences Research Program bulletin, 1971, Volume: 9, Issue:4

    Topics: Amino Acids; Animals; Antigens; Encephalomyelitis, Autoimmune, Experimental; Guinea Pigs; Mice; Myelin Basic Protein; Pepsin A; Rats; Skin Tests; Trypsin; Tryptophan; Urea

1971
The encephalitogenic dose response in guinea pigs of the tryptophan region of myelin basic protein.
    Immunological communications, 1974, Volume: 3, Issue:3

    Topics: Adjuvants, Immunologic; Amino Acid Sequence; Animals; Antigens; Brain; Dose-Response Relationship, Drug; Encephalomyelitis, Autoimmune, Experimental; Glutamine; Guinea Pigs; Mycobacterium; Mycobacterium tuberculosis; Myelin Basic Protein; Myelin Sheath; Peptides; Spinal Cord; Tryptophan

1974
Allergic encephalomyelitis: cleavage of the C-tryptophyl bond in the encephalitogenic basic protein from bovne myelin.
    Archives of biochemistry and biophysics, 1969, Volume: 131, Issue:1

    Topics: Allergens; Amino Acid Sequence; Amino Acids; Animals; Carboxypeptidases; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis; Encephalomyelitis, Autoimmune, Experimental; Guinea Pigs; Methods; Molecular Weight; Nerve Tissue Proteins; Pepsin A; Peptides; Periodic Acid; Spinal Cord; Tryptophan

1969
Letter: A mechanism for viral activation of multiple sclerosis.
    Journal of theoretical biology, 1974, Volume: 48, Issue:2

    Topics: Antigens, Viral; Encephalomyelitis, Autoimmune, Experimental; Glutamine; Models, Biological; Molecular Conformation; Multiple Sclerosis; Tryptophan

1974
The detection of autoantibody-forming cells. II. Cells in lymph nodes and central nervous system containing antibody to myelin basic protein.
    International archives of allergy and applied immunology, 1972, Volume: 43, Issue:5

    Topics: Animals; Antibody-Producing Cells; Autoantibodies; Central Nervous System; Encephalomyelitis, Autoimmune, Experimental; Erythrocytes; Guinea Pigs; Hemolytic Plaque Technique; Immunoglobulin Fab Fragments; Lymph Nodes; Male; Mice; Mice, Inbred CBA; Myelin Sheath; Nerve Tissue Proteins; Peptides; Sheep; Spleen; Tryptophan

1972
Species specificity in response to tryptophan modified encephalitogen.
    Immunochemistry, 1972, Volume: 9, Issue:1

    Topics: Amino Acid Sequence; Animals; Encephalomyelitis, Autoimmune, Experimental; Formates; Guinea Pigs; Haplorhini; Hydrochloric Acid; Myelin Sheath; Nerve Tissue Proteins; Nitrobenzenes; Nitrophenols; Peptides; Rabbits; Species Specificity; Sulfenic Acids; Tryptophan

1972
Antigen-induced inhibition of experimental allergic encephalomyelitis. I. Inhibition in guinea pigs injected with non-encephalitogenic modified myelin basic protein.
    Journal of immunology (Baltimore, Md. : 1950), 1972, Volume: 109, Issue:3

    Topics: Animals; Antigens; Electrophoresis; Encephalomyelitis, Autoimmune, Experimental; Freund's Adjuvant; Guinea Pigs; Immunization; Immunodiffusion; Myelin Sheath; Tryptophan

1972
Allergic encephalomyelitis: the physico-chemical properities of the basic protein encephalitogen from bovine spinal cord.
    Archives of biochemistry and biophysics, 1969, Volume: 129, Issue:2

    Topics: Allergens; Amino Acids; Animals; Autoanalysis; Biological Assay; Carbohydrates; Cattle; Chemical Phenomena; Chemistry; Encephalomyelitis, Autoimmune, Experimental; Guinea Pigs; Hemagglutination Inhibition Tests; Hot Temperature; Hydrogen-Ion Concentration; Immune Sera; Immunodiffusion; Molecular Weight; Nerve Tissue Proteins; Protein Denaturation; Spectrophotometry; Spinal Cord; Tryptophan; Ultracentrifugation; Viscosity

1969
Suppression of experimental allergic encephalomyelitis by chemically modified encephalitogen.
    Immunochemistry, 1972, Volume: 9, Issue:10

    Topics: Animals; Antigens; Binding Sites, Antibody; Brain Stem; Cerebellum; Electrophoresis, Polyacrylamide Gel; Encephalomyelitis, Autoimmune, Experimental; Formates; Guinea Pigs; Myelin Sheath; Nerve Tissue Proteins; Nitrobenzenes; Nitrophenols; Spectrophotometry; Spinal Cord; Sulfenic Acids; Tryptophan

1972
Allergic encephalomyelitis: a comparison of the encephalitogenic A1 protein from human and bovine brain.
    Archives of biochemistry and biophysics, 1970, Volume: 138, Issue:2

    Topics: Amino Acids; Animals; Brain; Brain Chemistry; Cattle; Cysteine; Electrophoresis; Encephalomyelitis, Autoimmune, Experimental; Hemagglutination Inhibition Tests; Hydrogen-Ion Concentration; Hypersensitivity, Delayed; Molecular Weight; Nerve Tissue Proteins; Optical Rotatory Dispersion; Peptides; Trypsin; Tryptophan; Ultracentrifugation

1970
Experimental allergic encephalomyelitis: synthesis of disease-inducing site of the basic protein.
    Science (New York, N.Y.), 1970, Jun-05, Volume: 168, Issue:3936

    Topics: Amino Acid Sequence; Animals; Binding Sites; Cattle; Encephalomyelitis, Autoimmune, Experimental; Guinea Pigs; Molecular Weight; Myelin Sheath; Peptides; Proteins; Tryptophan

1970
Localization of the active site through chemical modification of the encephalitogenic protein.
    The Journal of biological chemistry, 1970, Dec-10, Volume: 245, Issue:23

    Topics: Amino Acids; Animals; Binding Sites; Biological Assay; Bromides; Chemical Phenomena; Chemistry; Chlorides; Chromatography, Gel; Cyanides; Electrophoresis, Disc; Encephalomyelitis, Autoimmune, Experimental; Formates; Guinea Pigs; Methionine; Nerve Tissue Proteins; Nitrobenzenes; Nitrophenols; Peptide Hydrolases; Rabbits; Species Specificity; Tryptophan

1970
Isolation and partial characterization of some proteolytically and chemically derived fragments of bovine encephalitogenic protein.
    European journal of biochemistry, 1971, Jul-15, Volume: 21, Issue:1

    Topics: Amino Acids; Animals; Brain; Bromides; Bromine; Cattle; Chemical Phenomena; Chemistry; Chromatography; Electrophoresis, Disc; Encephalomyelitis, Autoimmune, Experimental; Indoles; Molecular Weight; Myelin Sheath; Nerve Tissue Proteins; Peptides; Tryptophan

1971