tryptophan has been researched along with Aging in 254 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 102 (40.16) | 18.7374 |
| 1990's | 36 (14.17) | 18.2507 |
| 2000's | 50 (19.69) | 29.6817 |
| 2010's | 44 (17.32) | 24.3611 |
| 2020's | 22 (8.66) | 2.80 |
| Authors | Studies |
|---|---|
| Garg, G; Rizvi, SI; Singh, AK; Singh, S; Verma, AK | 1 |
| Felder, TK; Gostner, JM; Laffon, B | 1 |
| Salminen, A | 1 |
| Bryan, RM; Durgan, DJ; Nelson, JW; Petrosino, JF; Phillips, S; Shi, H | 1 |
| Cabral-Marques, O; Dugué, PA; Giil, LM; Giles, GG; Halaas, NB; Hodge, A; Idland, AV; McCann, A; Midttun, Ø; Nordrehaug, JE; Nygård, O; Solvang, SH; Tell, GS; Ueland, PM; Ulvik, A; Watne, LO | 1 |
| Arefieva, AB; Evsiukova, VS; Kulikov, AV; Sorokin, IE | 1 |
| Badawy, AA | 2 |
| Caldez, MJ; Choi, H; Coppola, V; Eisenhaber, F; Goh, CMF; Gopinathan, L; Jones, OS; Kaldis, P; Kanagasundaram, Y; Kien, YL; Kurochkin, IV; Low, KN; Maurer-Stroh, S; Niska-Blakie, J; Ong, CB; Pfeiffenberger, E; Tessarollo, L | 1 |
| Deyn, PP; Kema, IP; Naudé, PJW; Nollen, EA; Sorgdrager, FJH | 1 |
| Fulzele, S; Hamrick, MW; Isales, CM; Johnson, M; Kaiser, H; McGee-Lawrence, ME; Mendhe, B; Pandya, C; Yu, K | 1 |
| Kim, BJ; Koh, JM; Lee, SH | 1 |
| Austad, M; Austad, SN; Henry, C; Hoffman, JM; Jones, DP; Kiklevich, JV; Royal, A; Tran, V | 1 |
| Hamrick, MW; Kaiser, H; Parker, E | 1 |
| Bollag, WB; Davis, C; Hamrick, MW; Hill, WD; Isales, CM; Johnson, MH; Kaiser, H; Kendall, RK; McGee-Lawrence, ME; Pierce, JL; Roberts, RL; Yu, K | 1 |
| Castro-Portuguez, R; Sutphin, GL | 1 |
| Araos, P; Colado, MI; Flores-López, M; García-Marchena, N; O'Shea, E; Pavón, FJ; Requena-Ocaña, N; Rodríguez de Fonseca, F; Rubio, G; Serrano, A; Suárez, J; Vidal, R | 1 |
| Anaya, JM; Bollag, WB; Hamrick, MW; Isales, CM | 1 |
| Brinkmann, V; Puchta, DR; Schiavi, A; Shaik, A; Ventura, N | 1 |
| Hu, Y; Ji, X; Lv, H; Peng, B; Wang, J; Wang, S; Yin, J; Yu, Z; Zhang, B | 1 |
| Hasan, M; Jung, BH; Kwon, OS; Lee, G; Lee, SH; Seo, JE | 1 |
| Chen, T; Wang, X; Yang, Y; Zhang, X | 1 |
| Adusumilli, S; Ding, K; Fulzele, S; Hamrick, MW; Hill, WD; Isales, CM; Pacholczyk, R; Patterson, GT; Sahay, B; Smith, K; Wankhade, UD; Yusufu, I | 1 |
| Agrawal, R; Hejndorf, S; Holmes, E; Low, JZY; Martin, KA; Matthews, PM; Nechanitzky, R; Ng, YZ; Nicholson, JK; Pettersson, S; Rossant, J; Tan, EK; Wei, GZ; Whiley, L; Wood, TK; Xing, PY | 1 |
| Ramprasath, T; Song, P; Wang, H; Zou, MH | 1 |
| Bendzunas, NG; Bollag, WB; Ding, KH; Elsalanty, M; Fulzele, S; Hamrick, MW; Hill, WD; Hunter, M; Isales, CM; Johnson, MH; Kennedy, EJ; McGee-Lawrence, ME; Pierce, JL; Refaey, ME; Shi, XM; Xu, J; Yu, K; Zhong, Q | 1 |
| Advani, R; Giil, LM; Midttun, Ø; Refsum, H; Smith, AD; Ueland, PM; Ulvik, A | 1 |
| Bosco, DA; Brown, RH; Hetz, C; Martínez Traub, F; Medinas, DB; Rozas, P; Woehlbier, U | 1 |
| Liu, JJ; Movassat, J; Portha, B | 1 |
| Andreasson, KI; Bernstein, D; Contrepois, K; Coronado, M; Dove, C; Joshi, AU; Lee, BA; Liu, L; Majeti, R; Mhatre, S; Migaud, M; Minhas, PS; Mochly-Rosen, D; Moon, PK; Rabinowitz, JD; Snyder, MP; Wang, Q | 1 |
| Hoffman, JM; Jones, DP; Promislow, DEL; Ross, C; Tardif, S; Tran, V | 1 |
| Hamrick, MW; Isales, CM; Kim, BJ; Kim, SJ; Koh, JM; Lee, SH; Yoo, HJ | 1 |
| Savitz, J | 1 |
| Bůžková, P; Carbone, LD; Coughlin, SS; Fink, HA; Isales, CM; Le, B; Raiford, M; Robbins, JA; Shikany, JM | 1 |
| Dantzer, R; Kelley, KW; Lawson, MA; McCusker, RH; O'Connor, JC; Rodriguez-Zas, SL | 1 |
| Bolaños-Jiménez, F; da Silva Aragão, R; de Souza, SL; Delacourt, N; Guzman-Quevedo, O; Kaeffer, B; Manhães-de-Castro, R; Nascimento, E; Perez-Garcia, G | 1 |
| Nollen, EA; van der Goot, AT | 1 |
| Eussen, SJ; Midttun, Ø; Nygård, O; Tell, GS; Theofylaktopoulou, D; Ueland, PM; Ulvik, A; Vollset, SE | 1 |
| Adomat, H; Budac, DP; Leavitt, BR; Lu, G; Mazarei, G; Möller, T; Tomlinson Guns, ES | 1 |
| Bell, JT; Brosnan, MJ; Deloukas, P; Erte, I; Gieger, C; John, S; Kastenmüller, G; Lim, EM; Menni, C; Mohney, R; Petersen, AK; Psatha, M; Schulz, H; Spector, TD; Stuckey, B; Suhre, K; Tsai, PC; Tsaprouni, L; Valdes, AM; Wilson, SG | 1 |
| Fuchs, D; Mangge, H; Postolache, TT; Reininghaus, EZ; Stelzer, I; Weghuber, D | 1 |
| Capuron, L; Fuchs, D; Geisler, S; Kurz, K; Leblhuber, F; Sperner-Unterweger, B | 1 |
| Dionne, IJ; Lorrain, D; Melancon, MO | 1 |
| Blaes, J; Bunse, L; Litzenburger, UM; Ochs, K; Opitz, CA; Ott, M; Platten, M; Pusch, S; Rauschenbach, KJ; Sahm, F; von Deimling, A; Wick, W | 1 |
| Emel'ianov, VV; Meshchaninov, VN; Shcherbakov, DL | 1 |
| Castorina, S; Castrogiovanni, P; Giunta, S; Imbesi, R; Loreto, C; Musumeci, G; Scuderi, S; Szychlinska, MA | 1 |
| de Bie, J; Grant, R; Guest, J; Guillemin, GJ | 1 |
| Feng, L; Jiang, J; Jiang, WD; Kuang, SY; Liu, Y; Tang, L; Tang, WN; Wen, HL; Wu, P; Zhang, YA; Zhao, J; Zhou, XQ | 1 |
| Abatedaga, I; Borsarelli, CD; Giménez, RE; Katz, NE; Mecchia Ortiz, JH; Morán Vieyra, FE; Ostatná, V; Paz Zanini, VI; Rey, V; Turbay, MB; Vargová, V | 1 |
| Genet, M; Gritsina, G; James, CD; Ladomersky, E; Lauing, KL; Wainwright, DA; Wu, M; Zhai, L | 1 |
| Brown-Borg, HM; Buffenstein, R | 1 |
| Castorina, S; Castrogiovanni, P; Giunta, S; Imbesi, R; Loreto, C; Musumeci, G; Szychlinska, MA | 1 |
| Babusikova, E; Dobrota, D; Jesenak, M; Kaplan, P; Racay, P | 1 |
| Campello-Costa, P; Faria Melibeu, Ada C; Oliveira-Silva, P; Serfaty, CA | 1 |
| Fukuwatari, T; Shibata, K; Wada, H | 1 |
| Barriga, C; Bejarano, I; Espino, J; Marchena, AM; Paredes, SD; Reiter, RJ; Rial, RV; Rodríguez, AB | 1 |
| Bhattacharyya, J; Ortwerth, BJ; Shipova, E | 1 |
| Funakoshi, H; Hayakawa, T; Kanai, M; Matsumoto, K; Mizuno, S; Nakamura, T; Takahashi, H | 1 |
| Barton, KA; Bhagyalaxmi, SG; Bhanuprakash Reddy, G; Kumar, KR; Padma, T; Petrash, JM; Srinivas, P; Vidyavathi, M | 1 |
| Barriga, C; Delgado, J; Paredes, SD; Reiter, RJ; Rodríguez, AB; Terrón, MP | 1 |
| Castrogiovanni, P; Imbesi, R; Mazzone, V | 1 |
| Chernyak, EI; Kolosova, NG; Kopylova, LV; Morozov, SV; Snytnikova, OA; Tsentalovich, YP | 1 |
| Brégère, C; Gallaher, TK; Rebrin, I; Sohal, RS | 1 |
| Aparicio, S; Barceló, P; Esteban, S; Fiol, MA; Garau, C; Moranta, D; Rial, R | 1 |
| Masalova, OO; Sapronov, NS | 1 |
| Oxenkrug, GF | 2 |
| Andrade, AC; Baron, J; Finkielstain, GP; Forcinito, P; Lui, JC; Nilsson, O | 1 |
| Back, K; Kang, K; Kim, YS; Kweon, SJ; Lee, K; Lee, S; Park, S | 1 |
| Mamata, M; Nagaraju, T; Padma, T; Reddy, KR; Sridhar, G | 1 |
| Bloomer, RJ; Canale, RE; Kabir, MM; Marshall, KE; Trepanowski, JF | 1 |
| Braidy, N; Chan-Ling, T; Grant, R; Guillemin, GJ; Mansour, H | 1 |
| Barriga, C; Bravo, R; Cubero, J; Franco, L; Matito, S; Paredes, SD; Rivero, M; Rodríguez, AB | 1 |
| BaHammam, AS; Bharti, VK; Brown, GM; Cardinali, DP; Hardeland, R; Kaur, C; Pandi-Perumal, SR; Spence, DW | 1 |
| Buijsman, RC; Dettmer, K; Farina, F; Kema, IP; Krijnen, J; Melki, R; Michels, H; Neri, C; Nollen, EA; Oefner, PJ; Ruiz Silva, M; Seinstra, RI; Thijssen, KL; van der Goot, AT; Vázquez-Manrique, RP; Zhu, W | 1 |
| Tan, L; Yu, JT | 1 |
| Aita, S; Iwanaga, T; Kameya, T; Kawai, Y; Matsushita, M; Ogawa, T; Okamoto, N; Saito, M; Yoneshiro, T | 1 |
| Casteleyn, C; Che, L; De Vos, M; Huygelen, V; Tambuyzer, B; Van Cruchten, S; Van Ginneken, C; Willemen, S; Zhang, K | 1 |
| Arai, R; Fujimiya, M; Jouvet, A; Kitahama, K; Nagatsu, I | 1 |
| Kalyanasundaram, S | 1 |
| Beas-Zárate, C; Del Angel, AR; Feria-Velasco, A; Manjarrrez, G; Orozco-Suárez, S | 1 |
| Birlouez-Aragon, I; de La Rochette, A; Morlière, P; Silva, E | 1 |
| Bakalli, RI; Driver, JP; Pesti, GM; Shan, AS; Sterling, KG; Tejedor, AA | 1 |
| Smith, DL; Smith, JB; Zhang, Z | 1 |
| GREGERMAN, RI | 1 |
| KNOX, WE; RIVLIN, RS | 1 |
| FORBES, RM; RAO, T | 1 |
| HAMFELT, A | 1 |
| Hussain, AM; Mitra, AK | 1 |
| Antar, RS; Faria, DE; Harms, RH; Russell, GB; Shivazad, M | 1 |
| Hishida, A; Takahira, R; Wada, N; Yonekawa, O; Yonemura, K | 1 |
| Fukao, M; Miwa, S; Takikawa, O; Truscott, RJ | 1 |
| Barnett, SR; Lewis, MC | 1 |
| Frick, B; Fuchs, D; Leblhuber, F; Neurauter, G; Schroecksnadel, K | 1 |
| Aschauer, HN; Basile, VS; Cavallaro, R; Chong, SA; Heresco-Levy, U; Kennedy, JL; Lerer, B; Macciardi, F; Meltzer, HY; Scharfetter, J; Segman, RH; Strous, R; Tan, EC; Verga, M | 1 |
| Albuquerque, SR; Badawy, AA; Farmer, A; Llewelyn, MB; Morgan, CJ | 1 |
| Backlund, PS; Bityurin, NM; Chelnokov, EV; Hejtmancik, JF; Ostrovsky, MA; Sergeev, YV; Soustov, LV; Wingfield, PT | 1 |
| Aparicio, S; Esteban, S; Garau, C; Nicolau, MC; Rial, RV | 2 |
| Estanislao, RB; Khaiat, A; Kollias, N; Li, J; Rivera, ZS; Stamatas, GN; Suero, M | 1 |
| Payne, JK | 1 |
| Korlimbinis, A; Truscott, RJ | 1 |
| Hervonen, A; Hurme, M; Jylhä, M; Karhunen, PJ; Lehtimäki, T; Oja, SS; Pertovaara, M; Raitala, A | 1 |
| Browndyke, J; Ghio, A; Schmechel, DE | 1 |
| Berger, M; Bruestle, K; Hohagen, F; Huwig-Poppe, C; Kordon, A; Kuelz, AK; Riemann, D; Voderholzer, U | 1 |
| Barriga, C; Cubero, J; Paredes, SD; Reiter, RJ; Rodríguez, AB; Terrón, M; Valero, V | 1 |
| Forouhar, F; Khan, JA; Tao, X; Tong, L | 1 |
| Barriga, C; Marchena, AM; Paredes, SD; Pariente, JA; Reiter, RJ; Rodríguez, AB; Terrón, MP | 2 |
| Brégère, C; Gallaher, TK; Kamzalov, S; Rebrin, I; Sohal, RS | 1 |
| Cheng, KC; Connor, JR; Goodman, SI; Housman, C; Jacobs, RE; LaNoue, K; Lazovic, J; O'Callaghan, JP; Simpson, I; Woontner, M; Zinnanti, WJ | 1 |
| Brammer, M; Cleare, AJ; Craig, MC; Cutter, WJ; Daly, EM; Lamar, M; Murphy, DG; Rubia, K | 1 |
| Barriga, C; Paredes, SD; Rodríguez, AB | 1 |
| Davies, MJ; Hains, PG; Jamie, JF; Mizdrak, J; Truscott, RJ | 1 |
| Isobe, K; Miura, H; Ozaki, N; Shirokawa, T | 1 |
| Babušíková, E; Dobrota, D; Jeseňák, M; Kaplán, P; Tribulová, N | 1 |
| Chandra, SV; Dubey, MP; Shukla, GS | 1 |
| Marchington, DR; Shargill, NS; York, DA | 1 |
| Godefroy, F; Stupfel, M; Weil-Fugazza, J | 1 |
| Mauron, C; Watkins, CJ; Wurtman, RJ; Zeisel, SH | 1 |
| Balemans, MG; de Reuver, GF; Pévet, P | 1 |
| Curzon, G; Hunt, A; Kantamaneni, BD; Patel, AJ; Sarna, GS; Tricklebank, MD | 1 |
| Duchala, CS; Ottinger, MA; Russek, E | 1 |
| Iriyama, K; Itoh, K; Iwamoto, T; Mizuno, A; Ozaki, Y; Yoshiura, M | 1 |
| Osanai, M | 1 |
| Dillon, J | 1 |
| Miller, M; Resnick, O | 1 |
| Hosoda, Y; Ikegami, N; Ishii, T; Shimada, H | 1 |
| Cornwell, GG; Murdoch, W; Pitkänen, P; Westermark, P | 1 |
| Braun, LD; Cornford, EM; Oldendorf, WH | 1 |
| Allegri, G; Baccichetti, F; Costa, C; De Antoni, A; Rubaltelli, FF; Vanzan, S | 1 |
| Fisher, C; Scougall, RK | 1 |
| Hoes, MJ; Kreutzer, EK; Sijben, N | 1 |
| Ashley, DV; Curzon, G | 1 |
| Endo, Y | 1 |
| Kent, S | 3 |
| Patnaik, SK; Sarangi, SK | 1 |
| Cooke, AR; Cooke, HJ; Pfankuche, L | 1 |
| Melethil, S; Tang, JP | 1 |
| Gafni, A; Schauerte, JA | 1 |
| Del Angel-Meza, AR; Feria-Velasco, A; González-Burgos, I; Olvera-Cortés, E | 2 |
| Fleming, TM; Hill, WL; Shrier, EM | 1 |
| Kamei, A | 1 |
| Greve, J; Otto, K; Puppels, GJ; Smeets, MH; Vrensen, GF | 1 |
| Kitoh, J; Kuroda, T; Masuda, K; Mizobuchi, M; Nakano, K; Takahashi, S | 1 |
| Faull, KF; Fisher, RS; Fluharty, AL; Gayek, RJ; Lazareff, JA; Olmstead, CE; Orlino, EN; Peacock, WJ; Wehby-Grant, MC | 1 |
| Cheeseman, K; Cottalasso, D; Marinari, UM; Odetti, P; Pronzato, MA; Traverso, N | 1 |
| Christmas, RB; Damron, BL; Ouart, MD | 1 |
| Coffey, MT; Spears, JW; van Heugten, E | 1 |
| Demling, J; Langer, K; Mehr, MQ | 1 |
| Manabe, S; Takahashi, T; Urban, RC; Yuan, J | 1 |
| Chao, CC; Ma, YS; Stadtman, ER | 1 |
| Meola, E; Mordenti, A; Panciroli, A; Piva, A; Sawadogo, ML; Sève, B | 1 |
| Del Angel-Meza, AR; Feria-Velasco, A; González-Burgos, I; Pérez-Vega, MI | 1 |
| Martin, L; Milena, A; Rodríguez Díaz, M; Santana, C; Santana-Herrera, C | 1 |
| Linetsky, M; Ortwerth, BJ; Ranson, N | 1 |
| Gao, J; Squier, TC; Williams, TD; Yao, Y; Yin, D | 1 |
| Arndt, H; Büettner, R; Cuk, A; Enger, I; Hügl, S; Nusser, J; Palitzsch, KD; Rogler, G; Schäffler, A; Schölmerich, J; Zietz, B | 1 |
| Bonaccorso, S; Bosmans, E; Dossche, A; Kenis, G; Lin, A; Maes, M; Scharpe, S; Song, C; Vandewoude, M; Verkerk, R | 1 |
| Bragina, JV; Heisenberg, M; Iliadi, KG; Kamyshev, NG; Kornhuber, J; Popov, AV; Riederer, P; Savvateeva, EV | 1 |
| Hayashi, K; Morioka, N; Okatani, Y | 1 |
| Jorissen, BL; Riedel, WJ | 1 |
| Bova, LM; Jamie, JF; Truscott, RJ; Wood, AM | 1 |
| Dillon, J; Paik, DC | 1 |
| Marklová, E | 1 |
| Fernstrom, JD | 1 |
| Girard, CL; Matte, JJ; Sève, B | 1 |
| Kawano, H; Matsushita, H; Ochi, M; Sakai, H; Takeuchi, Y | 1 |
| Bakalli, R; Edwards, HM; Pesti, GM; Rosa, AP | 1 |
| DiStefano, V; Taylor, LL | 1 |
| Segall, P | 1 |
| Honegger, P; Richelson, E | 1 |
| Richter, V; Rotzsch, W | 1 |
| Eberl, R; Partsch, G; Schwarzer, C; Tausch, G | 1 |
| Baker, HF; Crow, TJ; Jospeh, MH; Riley, GJ; Risby, D | 1 |
| Borkman, RF; Lerman, S | 1 |
| Streffer, C | 1 |
| Bourgoin, S; Hamon, M | 1 |
| Benignus, VA; Davis, JN; McNamara, MC; Miller, AT | 1 |
| Segall, PE | 1 |
| Angelova, AA; Stambolova, MA; Tsanev, RG | 1 |
| Brown, GM; Gauthier, S; Grota, LJ; Tsui, H; Young, SN | 1 |
| Dillon, J; Garcia-Castineiras, S; Spector, A | 1 |
| Gershon, D; Reznick, AZ | 1 |
| Horvath, SM; Rochelle, RD | 1 |
| Daniel, PM; Moorhouse, SR; Pratt, OE | 1 |
| Antonutto, G; Bartoli, M; Melato, M | 1 |
| Bozcuk, AN | 1 |
| Dobbing, J; Pickard, FJ; Tricklebank, MD | 1 |
| Artaud, F; Bourgoin, S; Enjalbert, A; Glowinski, J; Hamon, M; Héry, F | 1 |
| van Heyningen, R | 1 |
| Segall, PE; Timiras, PS | 1 |
| Curzon, G; Green, AR | 1 |
| Roy, D; Spector, A; Stauffer, J | 1 |
| Layman, DK; Ricca, GA; Richardson, A | 1 |
| Howells, DW; Hyland, K; Smith, I; Strobel, S | 1 |
| Abe, T; Takahashi, S | 1 |
| Ben-Harari, RR; Kleinerman, J; Parent Ermini, A | 1 |
| Elderfield, A; Truscott, R | 1 |
| Bondy, SC; LeBel, CP | 1 |
| Maurizi, CP | 1 |
| Liang, JN | 1 |
| Bazin, M; Cirne de Castro, J; Conte, J; Lawrence, D; Ribeiro, L; Sa e Melo, T; Santus, R | 1 |
| Comings, DE | 1 |
| Forsman, A; Hallgren, J; Larsson, M | 1 |
| Andley, UP; Clark, BA | 1 |
| Basova, NA; Kushak, RI | 1 |
| Andley, UP; Liang, JN; Rossi, MR | 1 |
| Leathwood, PD | 1 |
| Carlà, V; Lombardi, G; Moroni, F | 1 |
| Abou-Saleh, MT | 1 |
| Chagoya, G; Hernández-Rodríguez, J | 1 |
| Wilson, RP | 1 |
| Kato, H; Naito, H; Nam, TJ; Noguchi, T | 1 |
| Barron, BC; Kuck, JF; Yu, NT | 2 |
| Navab, F; Winter, CG | 1 |
| Lerman, S; Moran, M | 1 |
| Ooka, H; Segall, PE; Timiras, PS | 1 |
| Blondin, J; Taylor, A | 1 |
| Eble, JP; Goodrich, C | 1 |
| Fukagawa, NK; Minaker, KL; Rowe, JW; Young, VR | 1 |
| Bessems, GJ; Hoenders, HJ | 1 |
| Shaw, DM; Thomas, DR; Tidmarsh, SF | 1 |
| De Marte, ML; Enesco, HE | 2 |
| Cano, J; Machado, A; Santiago, M | 1 |
| Denoroy, L; Fety, R; Renaud, B; Sassard, J; Tappaz, ML; Vincent, M | 1 |
| Phipps, DA; Powell, C | 1 |
| Aragon, MC; Diez-Guerra, J; Gimenez, C; Herrero, E; Valdivieso, F | 1 |
| Bose, SK; Chakrabarti, B; Liang, JN | 1 |
| Kraus, H | 1 |
| Anderson, TJ; Ewen, SW | 1 |
| Sakamoto, H; Shimoyama, M; Takeuchi, T; Ueda, I; Yamaguchi, K | 1 |
| Shigehisa, S; Shimoyama, M; Ueda, I | 1 |
| Rauch, H; Siegel, SJ | 1 |
| Oliver, IT; Yeung, D | 1 |
| Benda, P; Bourgoin, S; Faivre-Bauman, A; Glowinski, J; Hamon, M | 1 |
| Badawy, AA; Evans, M | 1 |
| Boross, M; Pénzes, L | 1 |
| Pénzes, L | 2 |
| Arcce, CA; Barra, HS; Caputto, R; Rodriguez, JA | 1 |
| Murayama, K | 1 |
| Ronald, AP; Tsuyuki, H | 1 |
| Zigman, S | 1 |
| Correll, WW; Haining, JL | 2 |
| Correll, WW; Haining, JL; Turner, MD | 1 |
| Brunelli, A; Chiesara, E; Conti, F | 1 |
| Rosenthal, HL; Wu, SY | 1 |
31 review(s) available for tryptophan and Aging
| Article | Year |
|---|---|
Role of indoleamine 2,3-dioxygenase 1 (IDO1) and kynurenine pathway in the regulation of the aging process.
Topics: Aging; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenine; Tryptophan | 2022 |
Kynurenine pathway and human systems.
Topics: Aging; Cytokines; Humans; Kynurenine; Tryptophan | 2020 |
Tryptophan Metabolism in Inflammaging: From Biomarker to Therapeutic Target.
Topics: Aging; Animals; Biomarkers; Chronic Disease; Disease Susceptibility; Humans; Immunomodulation; Inflammation; Molecular Targeted Therapy; Tryptophan | 2019 |
Clinical insights into the kynurenine pathway in age-related diseases.
Topics: Aged; Aging; Animals; Biomarkers; Frailty; Humans; Kynurenine; Metabolic Networks and Pathways; Tryptophan | 2020 |
Kynurenine signaling through the aryl hydrocarbon receptor: Implications for aging and healthspan.
Topics: Aging; Animals; Basic Helix-Loop-Helix Transcription Factors; Humans; Inflammation; Kynurenine; Longevity; Mice; Reactive Oxygen Species; Receptors, Aryl Hydrocarbon; Signal Transduction; Tryptophan | 2020 |
Kynurenine pathway, NAD
Topics: Aging; Animals; Brain; Humans; Kynurenine; Longevity; Metabolic Networks and Pathways; Mice; Mitochondria; Mitophagy; NAD; Neurodegenerative Diseases; Oxidation-Reduction; Oxidative Stress; Tryptophan | 2020 |
The Role of Tryptophan Metabolites in Musculoskeletal Stem Cell Aging.
Topics: Aging; Animals; Humans; Musculoskeletal System; Stem Cells; Tryptophan | 2020 |
Abnormal kynurenine pathway of tryptophan catabolism in cardiovascular diseases.
Topics: Aging; Animals; Blood Pressure; Cardiovascular Diseases; Diabetes Mellitus; Drug Discovery; Endothelial Cells; Enzyme Inhibitors; Humans; Hydrolases; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Kynurenine 3-Monooxygenase; Obesity; Signal Transduction; Transaminases; Tryptophan | 2017 |
Emerging role for kynurenines in metabolic pathologies.
Topics: Aging; Animals; Atherosclerosis; Biomarkers; Diabetes Mellitus; Homeostasis; Humans; Islets of Langerhans; Kynurenine; Metabolic Diseases; Metabolic Networks and Pathways; Obesity; Tryptophan | 2019 |
The kynurenine pathway: a finger in every pie.
Topics: Aging; Animals; Energy Metabolism; Humans; Kynurenine; Mental Disorders; NAD; Neurodegenerative Diseases; Signal Transduction; Tryptophan | 2020 |
Tryptophan metabolism: entering the field of aging and age-related pathologies.
Topics: Aging; Animals; Humans; Signal Transduction; Tryptophan | 2013 |
Metabolomic markers reveal novel pathways of ageing and early development in human populations.
Topics: Adolescent; Adult; Aged; Aging; Biomarkers; Birth Weight; Bone Density; DNA Methylation; Forced Expiratory Volume; Humans; Metabolomics; Middle Aged; Phenotype; Tryptophan; Twins, Monozygotic; Vital Capacity; Young Adult | 2013 |
Disturbed tryptophan metabolism in cardiovascular disease.
Topics: Aging; Animals; Cardiovascular Diseases; Cardiovascular System; Humans; Inflammation; Mood Disorders; Sepsis; Tryptophan | 2014 |
Activated immune system and inflammation in healthy ageing: relevance for tryptophan and neopterin metabolism.
Topics: Aging; Animals; Health Status; Humans; Immunity, Cellular; Inflammation; Neopterin; Oxidative Stress; Reactive Oxygen Species; Tryptophan | 2014 |
Exercise and sleep in aging: emphasis on serotonin.
Topics: Aging; Amino Acids; Animals; Athletes; Exercise; Humans; Nerve Net; Preoptic Area; Raphe Nuclei; Reticular Formation; Serotonergic Neurons; Serotonin; Sleep; Sleep Disorders, Circadian Rhythm; Sleep Initiation and Maintenance Disorders; Tryptophan; Wakefulness | 2014 |
Tryptophan availability for kynurenine pathway metabolism across the life span: Control mechanisms and focus on aging, exercise, diet and nutritional supplements.
Topics: Aging; Animals; Diet; Dietary Supplements; Exercise; Humans; Kynurenine; Metabolic Networks and Pathways; Tryptophan | 2017 |
Cutting back on the essentials: Can manipulating intake of specific amino acids modulate health and lifespan?
Topics: Aging; Amino Acids; Animals; Caloric Restriction; Diet; Diet, Protein-Restricted; Healthy Aging; Humans; Longevity; Methionine; Quality of Life; Tryptophan | 2017 |
Nutritional tryptophan restriction and the role of serotonin in development and plasticity of central visual connections.
Topics: Aging; Animals; Brain; Developmental Disabilities; Humans; Infant; Infant Nutrition Disorders; Neuronal Plasticity; Rodentia; Serotonin; Tryptophan; Visual Pathways | 2008 |
Metabolic syndrome, age-associated neuroendocrine disorders, and dysregulation of tryptophan-kynurenine metabolism.
Topics: Aging; Animals; Endocrine System Diseases; Humans; Kynurenine; Metabolic Syndrome; Nervous System Diseases; Tryptophan | 2010 |
Impact of caloric and dietary restriction regimens on markers of health and longevity in humans and animals: a summary of available findings.
Topics: Adult; Aged; Aging; Animals; Biomarkers; Caloric Restriction; Cardiovascular Physiological Phenomena; Cholesterol, HDL; Cholesterol, LDL; Christianity; Diet, Reducing; Dietary Proteins; Energy Intake; Exercise; Fasting; Female; Humans; Islam; Life Expectancy; Longevity; Male; Methionine; Middle Aged; Motor Activity; Religion; Tryptophan | 2011 |
Melatonin antioxidative defense: therapeutical implications for aging and neurodegenerative processes.
Topics: Aging; Animals; Antioxidants; Apoptosis; Brain Injuries; Circadian Rhythm; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation, Preclinical; Free Radicals; Homeostasis; Humans; Light; Melatonin; Mice; Mice, Transgenic; Mitochondria; Multicenter Studies as Topic; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Oxidative Stress; Pineal Gland; Sleep Initiation and Maintenance Disorders; Tryptophan | 2013 |
The kynurenine pathway in neurodegenerative diseases: mechanistic and therapeutic considerations.
Topics: Aging; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Enzyme Inhibitors; Humans; Huntington Disease; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenic Acid; Kynurenine; Microglia; Molecular Targeted Therapy; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Neurotoxins; Parkinson Disease; Quinolinic Acid; Receptors, G-Protein-Coupled; Receptors, N-Methyl-D-Aspartate; Tryptophan | 2012 |
Combined analysis of 635 patients confirms an age-related association of the serotonin 2A receptor gene with tardive dyskinesia and specificity for the non-orofacial subtype.
Topics: Adult; Aged; Aging; Analysis of Variance; Chi-Square Distribution; Dyskinesia, Drug-Induced; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Histidine; Humans; International Cooperation; Logistic Models; Male; Middle Aged; Mutation; Polymorphism, Genetic; Receptor, Serotonin, 5-HT2A; Tryptophan | 2005 |
The trajectory of biomarkers in symptom management for older adults with cancer.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Aged; Aging; Anxiety; Biomarkers; Biomarkers, Tumor; Cytokines; Dehydroepiandrosterone; Estrogens; Evidence-Based Medicine; Fatigue; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Lymphocytes; Melatonin; Muscle Weakness; Nausea; Neoplasms; Sleep Wake Disorders; Stress, Psychological; T-Lymphocytes; Testosterone; Tryptophan; Vomiting | 2006 |
Nicotinamide adenine dinucleotide metabolism as an attractive target for drug discovery.
Topics: Acrylamides; Adenosine Diphosphate Ribose; Aging; Animals; Antineoplastic Agents; Autoimmune Diseases; Clinical Trials, Phase II as Topic; Cyclic ADP-Ribose; DNA Damage; Drug Design; Enzyme Inhibitors; Humans; Kynurenine; Mice; NAD; Neoplasms; Neurodegenerative Diseases; Neuroprotective Agents; Piperidines; Poly Adenosine Diphosphate Ribose; Signal Transduction; Sirtuins; Tryptophan | 2007 |
Genetic and hormonal regulation of tryptophan kynurenine metabolism: implications for vascular cognitive impairment, major depressive disorder, and aging.
Topics: Aging; Animals; Cognition Disorders; Cytokines; Depressive Disorder, Major; Hormones; Humans; Kynurenine; Models, Biological; Nitric Oxide Synthase Type II; Tryptophan | 2007 |
Nutrients, age and cognitive function.
Topics: Aged; Aging; Caffeine; Cognition; Diet; Dietary Supplements; Eating; Ginkgo biloba; Glucose; Humans; Nutritional Status; Plants, Medicinal; Tryptophan; Vitamins | 1998 |
Can nutrient supplements modify brain function?
Topics: Aging; Animals; Brain; Diet; Dietary Supplements; Fatty Acids, Unsaturated; Folic Acid; Hematinics; Humans; Nutritional Physiological Phenomena; Tryptophan; Tyrosine | 2000 |
Interrelations of dietary and hormonal effects in aging.
Topics: Aging; Animals; Autonomic Nervous System; Biological Clocks; Diet; Genes; Hypothalamus; Models, Biological; Muscle, Smooth; Muscles; Pituitary Gland, Anterior; Pituitary Hormones, Anterior; Rats; Spinal Cord; Tryptophan | 1979 |
Dexamethasone suppression tests in psychiatry: is there a place for an integrated hypothesis?
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aging; Animals; Antidepressive Agents; Corticotropin-Releasing Hormone; Depressive Disorder; Dexamethasone; Electroconvulsive Therapy; Humans; Hypothalamo-Hypophyseal System; Macaca mulatta; Male; Mental Disorders; Mice; Models, Theoretical; Nutritional Physiological Phenomena; Pituitary-Adrenal System; Prognosis; Rats; Receptors, Serotonin; Serotonin; Social Dominance; Stress, Physiological; Tryptophan | 1985 |
Protein and amino acid requirements of fishes.
Topics: Aging; Amino Acids; Animals; Arginine; Dietary Proteins; Energy Intake; Fishes; Histidine; Isoleucine; Leucine; Lysine; Methionine; Nutritional Requirements; Phenylalanine; Species Specificity; Threonine; Tryptophan; Valine | 1986 |
1 trial(s) available for tryptophan and Aging
| Article | Year |
|---|---|
Heterogeneity of serum tryptophan concentration and availability to the brain in patients with the chronic fatigue syndrome.
Topics: Adult; Aging; Brain Chemistry; Diagnosis, Differential; Eating; Fatigue Syndrome, Chronic; Female; Humans; Male; Middle Aged; Prospective Studies; Serotonin; Sex Characteristics; Tryptophan | 2005 |
222 other study(ies) available for tryptophan and Aging
| Article | Year |
|---|---|
Whey protein concentrate protects against age-dependent alteration in redox biomarkers.
Topics: Aging; Animals; Biomarkers; Cysteine; Drug Evaluation, Preclinical; Erythrocytes; Glycation End Products, Advanced; Lipid Metabolism; Male; Oxidative Stress; Rats, Wistar; Reactive Oxygen Species; Tryptophan; Tyrosine; Whey Proteins | 2020 |
Immunometabolism as predictor of frailty.
Topics: Aged; Aging; Frailty; Humans; Immune System; Immunosenescence; Tryptophan | 2021 |
Alterations of the gut microbial community structure and function with aging in the spontaneously hypertensive stroke prone rat.
Topics: Aging; Animals; Blood Pressure; Dysbiosis; Gastrointestinal Microbiome; Hypertension; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Stroke; Tryptophan | 2022 |
Kynurenine Pathway Metabolites in the Blood and Cerebrospinal Fluid Are Associated with Human Aging.
Topics: Aged; Aging; Child, Preschool; Frailty; Humans; Kynurenine; Quinolinic Acid; Tryptophan | 2022 |
Age-Related Alterations in the Level and Metabolism of Serotonin in the Brain of Males and Females of Annual Turquoise Killifish (
Topics: Aging; Animals; Brain; Cyprinodontiformes; Female; Fundulidae; Male; Monoamine Oxidase; Serotonin; Tryptophan; Tryptophan Hydroxylase | 2023 |
Knockout of the non-essential gene SUGCT creates diet-linked, age-related microbiome disbalance with a diabetes-like metabolic syndrome phenotype.
Topics: Aging; Animals; Anti-Bacterial Agents; Bacteria; Carnitine; Coenzyme A-Transferases; Dietary Supplements; Feces; Gastrointestinal Microbiome; Humans; Kidney; Lipid Metabolism; Liver; Lysine; Metabolic Syndrome; Metabolome; Mice; Mice, Knockout; Obesity; Tryptophan | 2020 |
Kynurenine, a Tryptophan Metabolite That Increases with Age, Induces Muscle Atrophy and Lipid Peroxidation.
Topics: Aging; Animals; Cells, Cultured; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Lipid Peroxidation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscular Atrophy; Myoblasts; Reactive Oxygen Species; Receptors, Aryl Hydrocarbon; Sarcopenia; Tryptophan | 2019 |
Tryptophan metabolism is differently regulated between large and small dogs.
Topics: Aging; Animals; Dogs; Longevity; Metabolomics; Pets; Tryptophan | 2020 |
Kynurenine suppresses osteoblastic cell energetics in vitro and osteoblast numbers in vivo.
Topics: Aging; Animals; Bone and Bones; Bone Density; Cell Differentiation; Female; Histone Deacetylases; Kynurenine; Male; Mice; Osteoblasts; Osteoporosis; Sex Characteristics; Tryptophan | 2020 |
Plasma tryptophan and kynurenine pathway metabolites in abstinent patients with alcohol use disorder and high prevalence of psychiatric comorbidity.
Topics: Adolescent; Adult; Aged; Aging; Alcohol Abstinence; Alcoholism; Body Mass Index; Cross-Sectional Studies; Diagnosis, Dual (Psychiatry); Female; Humans; Kynurenic Acid; Kynurenine; Male; Mental Disorders; Metabolic Networks and Pathways; Middle Aged; Serotonin; Sex Characteristics; Tryptophan; Young Adult | 2020 |
Dietary and environmental factors have opposite AhR-dependent effects on
Topics: Aging; Animals; Benzo(a)pyrene; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Diet; Environment; Escherichia coli; Heat-Shock Response; Longevity; Mutation; Receptors, Aryl Hydrocarbon; Stress, Physiological; Tryptophan; Ultraviolet Rays | 2020 |
Ameliorative Effect of Dietary Tryptophan on Neurodegeneration and Inflammation in d-Galactose-Induced Aging Mice with the Potential Mechanism Relying on AMPK/SIRT1/PGC-1α Pathway and Gut Microbiota.
Topics: Aging; AMP-Activated Protein Kinases; Animals; Diet; Galactose; Gastrointestinal Microbiome; Inflammation; Mice; Neurodegenerative Diseases; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Sirtuin 1; Tryptophan | 2021 |
Employing metabolomic approaches to determine the influence of age on experimental autoimmune encephalomyelitis (EAE).
Topics: Age Factors; Aging; Animals; Autoimmunity; Brain; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Fatty Acids, Unsaturated; Female; Interleukin-6; Metabolome; Metabolomics; Mice; Mice, Inbred C57BL; NADPH Oxidases; Risk Factors; Sphingolipids; Spinal Cord; Tryptophan; Tyrosine | 2021 |
Age-related functional changes of intestinal flora in rats.
Topics: Aging; Animals; Bacteria; Bacterial Proteins; Biosynthetic Pathways; DNA, Bacterial; Feces; Gastrointestinal Microbiome; Histidine; Humans; Male; Rats; Rats, Wistar; RNA, Ribosomal, 16S; Tryptophan | 2021 |
A Tryptophan-Deficient Diet Induces Gut Microbiota Dysbiosis and Increases Systemic Inflammation in Aged Mice.
Topics: Aging; Animals; Bacteria; Biodiversity; Cytokines; Diet; Feces; Gastrointestinal Microbiome; Inflammation; Male; Mice; Mice, Inbred C57BL; Phylogeny; Tryptophan | 2021 |
Tryptophan-metabolizing gut microbes regulate adult neurogenesis via the aryl hydrocarbon receptor.
Topics: Aging; Animals; Gastrointestinal Microbiome; Indoles; Male; Mice, Inbred C57BL; Mice, Knockout; Mutation; Neural Stem Cells; Neurogenesis; Receptors, Aryl Hydrocarbon; Tryptophan | 2021 |
Kynurenine, a Tryptophan Metabolite That Accumulates With Age, Induces Bone Loss.
Topics: Adiposity; Aging; Animals; Body Weight; Bone and Bones; Bone Resorption; Calcification, Physiologic; Cell Differentiation; Diet; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Male; Mesenchymal Stem Cells; Mice, Inbred C57BL; Osteoclasts; Tryptophan; X-Ray Microtomography | 2017 |
Kynurenine Pathway Metabolites in Alzheimer's Disease.
Topics: 3-Hydroxyanthranilic Acid; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Cognition Disorders; Cohort Studies; Female; Humans; Kynurenine; Male; Middle Aged; Neuropsychological Tests; Quinolinic Acid; Signal Transduction; Statistics, Nonparametric; Tryptophan; Xanthurenates | 2017 |
Endoplasmic reticulum stress leads to accumulation of wild-type SOD1 aggregates associated with sporadic amyotrophic lateral sclerosis.
Topics: Adult; Aged; Aged, 80 and over; Aging; Amyotrophic Lateral Sclerosis; Animals; Astrocytes; Brain; Cell Line; Disease Models, Animal; Endoplasmic Reticulum Stress; Female; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Middle Aged; Motor Neurons; Mutation; Oxidation-Reduction; Protein Aggregation, Pathological; Protein Folding; Proteostasis; Spinal Cord; Superoxide Dismutase-1; Tryptophan; Tunicamycin; Unfolded Protein Response | 2018 |
Macrophage de novo NAD
Topics: Aging; Animals; Cells, Cultured; Homeostasis; Immunity, Innate; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenine; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; NAD; Oxidative Phosphorylation; Pentosyltransferases; Phagocytosis; Signal Transduction; Tryptophan | 2019 |
The metabolome as a biomarker of mortality risk in the common marmoset.
Topics: Aging; Animal Husbandry; Animals; Betaine; Biomarkers; Callithrix; Female; Male; Metabolome; Methionine; Mortality; Tryptophan | 2019 |
The Detrimental Effects of Kynurenine, a Tryptophan Metabolite, on Human Bone Metabolism.
Topics: Aged; Aged, 80 and over; Aging; Bone and Bones; Bone Density; Bone Marrow; Bone Remodeling; Case-Control Studies; Female; Hip Fractures; Humans; Kynurenine; Male; Tryptophan | 2019 |
The Association of Aromatic Amino Acids with Incident Hip Fracture, aBMD, and Body Composition from the Cardiovascular Health Study.
Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Aging; Amino Acids, Aromatic; Body Composition; Body Mass Index; Bone Density; Diet; Diet Surveys; Ethnicity; Female; Hip Fractures; Humans; Male; Multivariate Analysis; Osteoporosis; Phenylalanine; Risk; Tryptophan; Tyrosine | 2019 |
Aging leads to prolonged duration of inflammation-induced depression-like behavior caused by Bacillus Calmette-Guérin.
Topics: Aging; Anhedonia; Animals; Behavior, Animal; Body Weight; Chronic Disease; Depression; Hindlimb Suspension; Illness Behavior; Inflammation; Kynurenine; Lung; Mice; Mice, Inbred BALB C; Motor Activity; Mycobacterium bovis; Mycobacterium Infections; Spleen; Tryptophan | 2013 |
Long-lasting effect of perinatal exposure to L-tryptophan on circadian clock of primary cell lines established from male offspring born from mothers fed on dietary protein restriction.
Topics: Aging; Animals; Animals, Newborn; Autophagy; Biomarkers; Blood Glucose; Cell Adhesion; Cell Line; Circadian Clocks; CLOCK Proteins; Colony-Forming Units Assay; Diet, Protein-Restricted; Energy Metabolism; Feeding Behavior; Female; Intra-Abdominal Fat; Lactation; Male; Maternal Exposure; Phenotype; Pregnancy; Rats; Serum; Tryptophan; Tryptophan Hydroxylase; Weight Gain | 2013 |
A community-based study on determinants of circulating markers of cellular immune activation and kynurenines: the Hordaland Health Study.
Topics: 3-Hydroxyanthranilic Acid; Aged; Aging; Biomarkers; Body Mass Index; Creatinine; Female; Humans; Inflammation; Kynurenic Acid; Kynurenine; Male; Middle Aged; Motor Activity; Neopterin; Norway; ortho-Aminobenzoates; Reference Values; Smoking; Tryptophan; Xanthurenates | 2013 |
Age-dependent alterations of the kynurenine pathway in the YAC128 mouse model of Huntington disease.
Topics: Aging; Animals; Brain; Cerebellum; Corpus Striatum; Female; Genotype; Huntington Disease; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Male; Mice; Quinolinic Acid; Serotonin; Signal Transduction; Tryptophan; Tryptophan Oxygenase | 2013 |
Suppression of TDO-mediated tryptophan catabolism in glioblastoma cells by a steroid-responsive FKBP52-dependent pathway.
Topics: Aging; Animals; Cell Line, Tumor; Dexamethasone; Glioblastoma; Humans; Mice; Signal Transduction; Tacrolimus; Tacrolimus Binding Proteins; Tryptophan; Tryptophan Oxygenase | 2015 |
[Tryptophan and nicotinic acid as antioxidants in different age rats brain at the immobilization stress].
Topics: Aging; Animals; Antioxidants; Brain; Drug Therapy, Combination; Lipid Peroxides; Male; Niacin; Rats, Wistar; Restraint, Physical; Stress, Psychological; Treatment Outcome; Tryptophan | 2014 |
Changes in serotonin (5-HT) and brain-derived neurotrophic factor (BDFN) expression in frontal cortex and hippocampus of aged rat treated with high tryptophan diet.
Topics: Aging; Animals; Blotting, Western; Brain-Derived Neurotrophic Factor; Diet; Diet Therapy; Enzyme-Linked Immunosorbent Assay; Frontal Lobe; Hippocampus; Immunohistochemistry; Random Allocation; Rats, Sprague-Dawley; Serotonin; Tryptophan | 2015 |
Central kynurenine pathway shift with age in women.
Topics: Adult; Aged; Aged, 80 and over; Aging; Brain; Female; Humans; Inflammation; Kynurenic Acid; Kynurenine; Middle Aged; Neopterin; Neurotoxins; Quinolinic Acid; Tryptophan; Tryptophan Oxygenase; Young Adult | 2016 |
Enhanced muscle nutrient content and flesh quality, resulting from tryptophan, is associated with anti-oxidative damage referred to the Nrf2 and TOR signalling factors in young grass carp (Ctenopharyngodon idella): Avoid tryptophan deficiency or excess.
Topics: Aging; Animals; Antioxidants; Carps; Muscle, Skeletal; NF-E2-Related Factor 2; Signal Transduction; TOR Serine-Threonine Kinases; Tryptophan | 2016 |
Interaction of singlet oxygen with bovine serum albumin and the role of the protein nano-compartmentalization.
Topics: 2,2'-Dipyridyl; Aging; Coordination Complexes; Hydrophobic and Hydrophilic Interactions; Kinetics; Oxidation-Reduction; Oxidative Stress; Protein Binding; Serum Albumin, Bovine; Singlet Oxygen; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tryptophan | 2016 |
Advanced age negatively impacts survival in an experimental brain tumor model.
Topics: Aging; Animals; Brain Neoplasms; Cell Line, Tumor; Disease Models, Animal; Glioblastoma; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Lymphocytes, Tumor-Infiltrating; Mice; Mice, Inbred C57BL; Survival Analysis; Tryptophan | 2016 |
Protective effects of high Tryptophan diet on aging-induced passive avoidance impairment and hippocampal apoptosis.
Topics: Aging; Animal Feed; Animals; Apoptosis; Avoidance Learning; bcl-2-Associated X Protein; Caspase 3; Cyclic AMP Response Element-Binding Protein; Dietary Supplements; Hippocampus; Proto-Oncogene Proteins c-bcl-2; Random Allocation; Rats, Sprague-Dawley; Serotonin; Tryptophan | 2017 |
Oxidative alternations in rat heart homogenate and mitochondria during ageing.
Topics: Aging; Anilino Naphthalenesulfonates; Animals; Electron Transport Complex IV; Fluorescent Dyes; Lipid Peroxidation; Lysine; Male; Mitochondria, Heart; Myocardium; Oxidation-Reduction; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Tryptophan; Tyrosine | 2008 |
Age-related alterations of B-group vitamin contents in urine, blood and liver from rats.
Topics: Age Factors; Aging; Animals; Biotin; Body Weight; Eating; Folic Acid; Liver; Male; Models, Animal; Niacinamide; Pyridoxal Phosphate; Rats; Tryptophan; Vitamin B 12; Vitamin B Complex | 2008 |
Melatonin and tryptophan affect the activity-rest rhythm, core and peripheral temperatures, and interleukin levels in the ringdove: changes with age.
Topics: Administration, Oral; Aging; Animals; Body Temperature Regulation; Circadian Rhythm; Columbidae; Female; Interleukins; Male; Melatonin; Models, Animal; Motor Activity; Multivariate Analysis; Probability; Regression Analysis; Sensitivity and Specificity; Sleep Stages; Tryptophan; Wakefulness | 2009 |
Tryptophan metabolites from young human lenses and the photooxidation of ascorbic acid by UVA light.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Ascorbic Acid; Chromatography, High Pressure Liquid; Crystallins; Glucosides; Glutathione; Humans; Lens, Crystalline; Mass Spectrometry; Middle Aged; Oxidation-Reduction; Phenylbutyrates; Radiation-Sensitizing Agents; Subcellular Fractions; Tryptophan; Ultraviolet Rays | 2009 |
Tryptophan 2,3-dioxygenase is a key modulator of physiological neurogenesis and anxiety-related behavior in mice.
Topics: Aging; Animals; Anxiety; Behavior, Animal; Cell Proliferation; Cerebral Ventricles; Dentate Gyrus; Gene Deletion; Gene Targeting; Genetic Loci; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Neural Stem Cells; Neurogenesis; Olfactory Bulb; Serotonin; Tryptophan | 2009 |
A novel mutation (F71L) in alphaA-crystallin with defective chaperone-like function associated with age-related cataract.
Topics: Aging; alpha-Crystallin A Chain; Amino Acid Substitution; Base Sequence; Case-Control Studies; Cataract; Chromatography, Gel; Circular Dichroism; DNA Mutational Analysis; Electrophoresis, Polyacrylamide Gel; Exons; Female; Genetic Predisposition to Disease; Humans; Light; Male; Middle Aged; Molecular Sequence Data; Mutant Proteins; Mutation; Protein Structure, Quaternary; Scattering, Radiation; Spectrometry, Fluorescence; Time Factors; Tryptophan | 2009 |
Effect of melatonin and tryptophan on humoral immunity in young and old ringdoves (Streptopelia risoria).
Topics: Administration, Oral; Aging; Animals; Columbidae; Female; Immunity, Humoral; Male; Melatonin; Tryptophan | 2009 |
Is tryptophan 'more' essential than other essential aminoacids in development? A morphologic study.
Topics: Adrenal Glands; Aging; Amino Acids, Essential; Animal Feed; Animals; Body Size; Body Weight; Diet; Dwarfism; Embryo, Mammalian; Female; Genitalia, Male; Growth Hormone; Lactation; Male; Pregnancy; Rats; Rats, Sprague-Dawley; Sex Differentiation; Tryptophan | 2009 |
Tryptophan and kynurenine levels in lenses of Wistar and accelerated-senescence OXYS rats.
Topics: Aging; Animals; Chromatography, High Pressure Liquid; Kynurenine; Lens, Crystalline; Rats; Rats, Wistar; Tryptophan | 2009 |
Effects of age and calorie restriction on tryptophan nitration, protein content, and activity of succinyl-CoA:3-ketoacid CoA transferase in rat kidney mitochondria.
Topics: Age Factors; Aging; Animals; Caloric Restriction; Catalytic Domain; Coenzyme A-Transferases; Ketones; Kidney; Male; Mass Spectrometry; Mitochondria; Nitrogen; Rats; Rats, Inbred F344; Tryptophan | 2010 |
Chronic melatonin treatment and its precursor L-tryptophan improve the monoaminergic neurotransmission and related behavior in the aged rat brain.
Topics: Aging; Animals; Antioxidants; Behavior, Animal; Brain; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Hippocampus; Male; Melatonin; Norepinephrine; Rats; Rats, Sprague-Dawley; Serotonin; Synaptic Transmission; Tryptophan | 2010 |
The role of the serotoninergic system in the regulation of thyroid function in old rats.
Topics: Aging; Animals; Citalopram; Male; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Thyroid Function Tests; Thyroid Gland; Thyroidectomy; Thyrotropin; Thyroxine; Triiodothyronine; Tryptophan | 2009 |
Growth-inhibiting conditions slow growth plate senescence.
Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Chondrocytes; Growth Plate; Male; Propylthiouracil; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Tryptophan | 2011 |
Tryptophan boost caused by senescence occurred independently of cytoplasmic glutamine synthetase.
Topics: Aging; Cytosol; Glutamate-Ammonia Ligase; Glutamine; Oryza; Plants, Genetically Modified; RNA Interference; RNA, Messenger; Tryptophan | 2010 |
Is the variant c.422+90G → A in intron 4 of indoleamine 2, 3 -dioxygenase (IDO) gene related to age related cataracts?
Topics: Age of Onset; Aged; Aged, 80 and over; Aging; Body Mass Index; Case-Control Studies; Cataract; Exons; Eye; Eye Proteins; Female; Humans; India; Indoleamine-Pyrrole 2,3,-Dioxygenase; Introns; Lens, Crystalline; Male; Middle Aged; Polymorphism, Restriction Fragment Length; Restriction Mapping; Risk Factors; Sex Factors; Smoking; Tryptophan | 2011 |
Changes in kynurenine pathway metabolism in the brain, liver and kidney of aged female Wistar rats.
Topics: Aging; Animals; Brain; Chromatography, High Pressure Liquid; Female; Gas Chromatography-Mass Spectrometry; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kidney; Kynurenine; Liver; Pentosyltransferases; Picolinic Acids; Quinolinic Acid; Rats; Rats, Wistar; Signal Transduction; Transaminases; Tryptophan; Tryptophan Oxygenase | 2011 |
Tryptophan-enriched cereal intake improves nocturnal sleep, melatonin, serotonin, and total antioxidant capacity levels and mood in elderly humans.
Topics: Affect; Aged; Aging; Antioxidants; Circadian Rhythm; Edible Grain; Female; Humans; Male; Melatonin; Middle Aged; Serotonin; Sleep; Tryptophan | 2013 |
Delaying aging and the aging-associated decline in protein homeostasis by inhibition of tryptophan degradation.
Topics: Aging; alpha-Synuclein; Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Chromatography, Liquid; Computational Biology; DNA Primers; Fertility; Homeostasis; Immunoblotting; Longevity; Peptides; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Tandem Mass Spectrometry; Tryptophan; Tryptophan Oxygenase | 2012 |
Impact of UCP1 and β3AR gene polymorphisms on age-related changes in brown adipose tissue and adiposity in humans.
Topics: Adipose Tissue, Brown; Adiposity; Adult; Aged; Aging; Arginine; Energy Metabolism; Female; Fluorodeoxyglucose F18; Healthy Volunteers; Humans; Ion Channels; Japan; Male; Middle Aged; Mitochondrial Proteins; Polymorphism, Single Nucleotide; Positron-Emission Tomography; Radiopharmaceuticals; Receptors, Adrenergic, beta-3; Thermogenesis; Tomography, X-Ray Computed; Tryptophan; Uncoupling Protein 1 | 2013 |
Perinatal growth restriction is not related to higher intestinal distribution and increased serum levels of 5-hydroxytryptamin in piglets.
Topics: Aging; Animals; Female; Fetal Weight; Gene Expression Regulation, Developmental; Intestines; Pregnancy; Serotonin; Swine; Tryptophan | 2012 |
5-Hydroxytryptophan (5-HTP) uptake and decarboxylation in the kitten brain.
Topics: 5-Hydroxytryptophan; Aging; Animals; Animals, Newborn; Brain; Cats; Decarboxylation; Drug Combinations; Female; Male; Monoamine Oxidase Inhibitors; Pargyline; Serotonin; Sodium Chloride; Tissue Distribution; Tryptophan | 2002 |
Effect of dietary protein and calorie deficiency on tryptophan levels in the developing rat brain.
Topics: Aging; Animals; Brain; Dietary Proteins; Energy Intake; Rats; Time; Tryptophan | 1976 |
Corn feeding during development induces changes in the number of serotonergic neurons in the raphe nuclei.
Topics: Aging; Animal Feed; Animals; Animals, Newborn; Body Weight; Diet, Protein-Restricted; Female; Neurons; Raphe Nuclei; Rats; Rats, Inbred WF; Reference Values; Reproducibility of Results; Seeds; Sensitivity and Specificity; Serotonin; Tryptophan; Zea mays | 2003 |
Advanced glycation endproducts as UVA photosensitizers of tryptophan and ascorbic acid: consequences for the lens.
Topics: Aging; Antioxidants; Ascorbic Acid; Glycation End Products, Advanced; Humans; Lens, Crystalline; Oxidation-Reduction; Oxygen; Photosensitizing Agents; Riboflavin; Tryptophan; Ultraviolet Rays | 2003 |
The influence of temperature on the threonine and tryptophan requirements of young broiler chicks.
Topics: Aging; Animal Nutritional Physiological Phenomena; Animals; Chickens; Diet; Dietary Supplements; Eating; Glutens; Glycine max; Hot Temperature; Nutritional Requirements; Temperature; Threonine; Tryptophan; Weight Gain; Zea mays | 2003 |
Human beta-crystallins modified by backbone cleavage, deamidation and oxidation are prone to associate.
Topics: Adult; Aged; Aged, 80 and over; Aging; beta-Crystallin A Chain; beta-Crystallin B Chain; Child; Child, Preschool; Chromatography, High Pressure Liquid; Crystallins; Electrophoresis, Gel, Two-Dimensional; Humans; Lens, Crystalline; Methionine; Middle Aged; Oxidation-Reduction; Protein Biosynthesis; Tryptophan | 2003 |
Adaptive enzyme responses in the senescent rat: tryptophan peroxidase and tyrosine transaminase.
Topics: Aging; Animals; Oxidoreductases; Peroxidase; Peroxidases; Rats; Transaminases; Tryptophan; Tyrosine Transaminase | 1959 |
Effects of age, body size and growth hormone on level of tryptophan peroxidase-oxidase in rat liver.
Topics: Aging; Animals; Body Size; Body Weight; Cataract; Growth Hormone; Human Growth Hormone; Liver; Oxidoreductases; Peroxidase; Peroxidases; Rats; Tryptophan | 1959 |
The effect of age on the net requirements for nitrogen, lysine and tryptophan by the well-fed rat.
Topics: Aging; Animals; Biochemical Phenomena; Lysine; Nitrogen; Purines; Rats; Tryptophan | 1959 |
AGE VARIATION OF VITAMIN B6 METABOLISM IN MAN.
Topics: Adolescent; Aging; Aspartate Aminotransferases; Blood Chemical Analysis; Body Fluids; Child; Geriatrics; Humans; Infant; Infant, Newborn; Intestinal Absorption; Male; Metabolism; Middle Aged; Oxidative Phosphorylation; Phosphates; Pyridoxine; Statistics as Topic; Tryptophan; Urine | 1964 |
Effect of reactive oxygen species on the metabolism of tryptophan in rat brain: influence of age.
Topics: Aging; Animals; Brain; Oxidation-Reduction; Oxidoreductases; Rats; Rats, Inbred Strains; Reactive Oxygen Species; Sulfhydryl Compounds; Tryptophan; Tryptophan Hydroxylase | 2004 |
Performance of commercial laying hens when six percent corn oil is added to the diet at various ages and with different levels of tryptophan and protein.
Topics: Aging; Animals; Chickens; Corn Oil; Diet; Dietary Proteins; Eggs; Energy Intake; Female; Oviposition; Tryptophan | 2004 |
The diagnostic value of serum concentrations of 2-(alpha-mannopyranosyl)-L-tryptophan for normal renal function.
Topics: Adolescent; Adult; Aging; Area Under Curve; Child; Creatinine; Female; Humans; Ketoses; Kidney Function Tests; Male; Middle Aged; Osmolar Concentration; Predictive Value of Tests; Reference Values; ROC Curve; Sensitivity and Specificity; Tryptophan | 2004 |
Age-related nuclear cataract and indoleamine 2,3-dioxygenase-initiated tryptophan metabolism in the human lens.
Topics: Adult; Aged; Aged, 80 and over; Aging; Blotting, Western; Cataract; Chromatography, High Pressure Liquid; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Lens, Crystalline; Middle Aged; Tryptophan; Tryptophan Oxygenase; Ultraviolet Rays | 2003 |
Postoperative delirium: the tryptophan dyregulation model.
Topics: Aged; Aged, 80 and over; Aging; Brain; Delirium; Humans; Melatonin; Models, Neurological; Postoperative Complications; Serotonin; Tryptophan | 2004 |
Increasing production of homocysteine and neopterin and degradation of tryptophan with older age.
Topics: Adult; Aged; Aged, 80 and over; Aging; Dioxygenases; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Homocysteine; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynurenine; Macrophages; Male; Middle Aged; Neopterin; T-Lymphocytes; Time Factors; Tryptophan; Vitamin B 12 | 2004 |
Increased sensitivity of amino-arm truncated betaA3-crystallin to UV-light-induced photoaggregation.
Topics: Aging; Animals; Baculoviridae; beta-Crystallin A Chain; Blotting, Western; Cataract; Chromatography, Gel; Crystallins; Electrophoresis, Polyacrylamide Gel; Gene Expression; Light; Methionine; Mice; Oxidation-Reduction; Photochemistry; Photolysis; Protein Denaturation; Recombinant Proteins; Scattering, Radiation; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tryptophan; Ultraviolet Rays | 2005 |
Age-related changes in circadian rhythm of serotonin synthesis in ring doves: effects of increased tryptophan ingestion.
Topics: Aging; Animals; Circadian Rhythm; Columbidae; Corpus Striatum; Hippocampus; Hypothalamus; Melatonin; Serotonin; Tryptophan | 2006 |
Facial skin fluorescence as a marker of the skin's response to chronic environmental insults and its dependence on age.
Topics: Adolescent; Adult; Age Distribution; Aged; Aging; Cell Proliferation; Environment; Epidermal Cells; Epidermis; Ethnicity; Face; Humans; Middle Aged; Regeneration; Seasons; Skin; Skin Aging; Spectrometry, Fluorescence; Sunlight; Tryptophan | 2006 |
Identification of 3-hydroxykynurenine bound to proteins in the human lens. A possible role in age-related nuclear cataract.
Topics: Aging; Animals; Butterflies; Cataract; Humans; Kynurenine; Lens, Crystalline; Moths; Oxidation-Reduction; Peptides; Pigmentation; Protein Binding; Proteins; Solubility; Sunscreening Agents; Time Factors; Tryptophan; Ultraviolet Rays | 2006 |
Indoleamine 2,3-dioxygenase activity in nonagenarians is markedly increased and predicts mortality.
Topics: Adult; Aged, 80 and over; Aging; Female; Humans; Immune System; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Longevity; Male; Middle Aged; Models, Biological; T-Lymphocytes; Tryptophan | 2006 |
Age related changes in the activity-rest circadian rhythms and c-fos expression of ring doves with aging. Effects of tryptophan intake.
Topics: Activity Cycles; Aging; Animals; Body Temperature Regulation; Circadian Rhythm; Columbidae; Gene Expression; Immunohistochemistry; Jet Lag Syndrome; Melatonin; Models, Animal; Proto-Oncogene Proteins c-fos; Receptors, Melatonin; Sleep; Tryptophan | 2006 |
Strategies for dissecting genetic-environmental interactions in neurodegenerative disorders.
Topics: Adult; Age Factors; Age of Onset; Aged; Aged, 80 and over; Aging; alpha 1-Antitrypsin; Analysis of Variance; Apolipoprotein E4; Apolipoproteins E; Chi-Square Distribution; Cysteine; DNA Mutational Analysis; Environment; Female; Gene Frequency; Genetic Predisposition to Disease; Hemochromatosis; Humans; Male; Middle Aged; Mutation; Neurodegenerative Diseases; Phenotype; Retrospective Studies; Tryptophan | 2006 |
Sleep in obsessive compulsive disorder: polysomnographic studies under baseline conditions and after experimentally induced serotonin deficiency.
Topics: Adult; Aging; Electroencephalography; Female; Humans; Male; Middle Aged; Obsessive-Compulsive Disorder; Polysomnography; Psychiatric Status Rating Scales; Serotonin; Sleep; Sleep Stages; Sleep, REM; Tryptophan | 2007 |
Tryptophan increases nocturnal rest and affects melatonin and serotonin serum levels in old ringdove.
Topics: Aging; Analysis of Variance; Animals; Circadian Rhythm; Columbidae; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Male; Melatonin; Radioimmunoassay; Rest; Serotonin; Tryptophan | 2007 |
Effect of exogenous melatonin on viability, ingestion capacity, and free-radical scavenging in heterophils from young and old ringdoves (Streptopelia risoria).
Topics: Aging; Animals; Cell Survival; Circadian Rhythm; Columbidae; Female; Free Radical Scavengers; Free Radicals; Leukocytes; Male; Melatonin; Oxidation-Reduction; Phagocytosis; Tryptophan | 2007 |
Tryptophan modulates cell viability, phagocytosis and oxidative metabolism in old ringdoves.
Topics: Aging; Animals; Cell Survival; Circadian Rhythm; Columbidae; Female; Male; Melatonin; Oxidation-Reduction; Phagocytosis; Serotonin; Superoxides; Tryptophan | 2007 |
Nitration of tryptophan 372 in succinyl-CoA:3-ketoacid CoA transferase during aging in rat heart mitochondria.
Topics: Acyl Coenzyme A; Aged; Aging; Animals; Coenzyme A-Transferases; Humans; Male; Mitochondria; Myocardium; Nitrates; Rats; Rats, Inbred F344; Tryptophan | 2007 |
Mechanism of age-dependent susceptibility and novel treatment strategy in glutaric acidemia type I.
Topics: Aging; Amino Acid Metabolism, Inborn Errors; Animals; Brain Diseases, Metabolic, Inborn; Child; Diet; Disease Models, Animal; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Glucose; Glutamic Acid; Glutarates; Glutaryl-CoA Dehydrogenase; Homoarginine; Humans; Lysine; Mice; Mice, Knockout; Mitochondria; Neurons; Nuclear Magnetic Resonance, Biomolecular; Tryptophan | 2007 |
5-HT, prefrontal function and aging: fMRI of inhibition and acute tryptophan depletion.
Topics: Acute Disease; Adaptation, Physiological; Aged; Aging; Biomarkers; Brain; Brain Mapping; Female; Functional Laterality; Humans; Magnetic Resonance Imaging; Middle Aged; Neural Inhibition; Neural Pathways; Neuropsychological Tests; Prefrontal Cortex; Serotonin; Surveys and Questionnaires; Tryptophan | 2009 |
Melatonin and tryptophan as therapeutic agents against the impairment of the sleep-wake cycle and immunosenescence due to aging in Streptopelia risoria.
Topics: Activity Cycles; Aging; Animals; Columbidae; Leukocytes; Melatonin; Neuroimmunomodulation; Phagocytosis; Serotonin; Sleep; Superoxides; Tryptophan; Wakefulness | 2007 |
Tryptophan-derived ultraviolet filter compounds covalently bound to lens proteins are photosensitizers of oxidative damage.
Topics: Aging; Animals; Cattle; Chromatography, High Pressure Liquid; Crystallins; Electrophoresis, Polyacrylamide Gel; Hydrogen Peroxide; Lens, Crystalline; Oxidative Stress; Tryptophan; Ultraviolet Rays | 2008 |
Changes in brain tryptophan metabolism elicited by ageing, social environment, and psychological stress in mice.
Topics: Aging; Amygdala; Animals; Brain; Brain Chemistry; Hippocampus; Kynurenine; Male; Mice; Mice, Inbred ICR; Prefrontal Cortex; Raphe Nuclei; Serotonin; Social Isolation; Stress, Psychological; Tryptophan | 2008 |
Age-dependent effect of oxidative stress on cardiac sarcoplasmic reticulum vesicles.
Topics: Age Factors; Aging; Animals; Hydrophobic and Hydrophilic Interactions; Intracellular Membranes; Lipid Peroxidation; Lysine; Male; Myocardium; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Sarcoplasmic Reticulum; Subcellular Fractions; Thiobarbituric Acid Reactive Substances; Tryptophan | 2008 |
Managanese-induced biochemical changes in growing versus adult rats.
Topics: Aging; Animals; Biogenic Amines; Body Weight; Brain Chemistry; Liver; Male; Manganese; Metals; Neurotransmitter Agents; Rats; Tryptophan; Tyrosine | 1980 |
Regulation of hepatic tyrosine aminotransferase in genetically obese rats.
Topics: Adrenalectomy; Aging; Amino Acids; Animals; Corticosterone; Diet; Disease Models, Animal; Enzyme Activation; Insulin; Liver; Obesity; Rats; Tryptophan; Tyrosine; Tyrosine Transaminase | 1983 |
Relation of sex and ageing to serotonin metabolism in rats.
Topics: Aging; Animals; Blood Platelets; Brain Chemistry; Female; Hydroxyindoleacetic Acid; Male; Rats; Serotonin; Sex Factors; Tryptophan | 1980 |
Developmental changes in brain indoles, serum tryptophan and other serum neutral amino acids in the rat.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Brain; Fasting; Female; Hydroxyindoleacetic Acid; Indoles; Male; Rats; Serotonin; Tryptophan | 1981 |
The pineal gland of the mole (Talpa europaea L.). VII. Activity of hydroxyindole-O-methyltransferase (HIOMT) in the formation of 5-methoxytryptophan, 5-methoxytryptamine, 5-methoxyindole-3-acetic acid, 5-methoxytryptophol and melantonin in the eyes and th
Topics: 5-Methoxytryptamine; Acetylserotonin O-Methyltransferase; Aging; Animals; Eulipotyphla; Eye; Female; Hydroxyindoleacetic Acid; Indoles; Male; Melatonin; Methyltransferases; Moles; Organ Specificity; Pineal Gland; Sex Factors; Sexual Maturation; Tryptamines; Tryptophan | 1981 |
Effect of age on variables influencing the supply of tryptophan to the brain.
Topics: Aging; Amino Acids; Animals; Biological Transport; Blood-Brain Barrier; Brain; Fatty Acids, Nonesterified; Hydroxyindoleacetic Acid; Kinetics; Male; Rats; Serotonin; Tryptophan | 1982 |
The developmental distribution of monoamines in the brain of male Japanese quail (Coturnix coturnix japonica).
Topics: Aging; Animals; Brain; Brain Stem; Catecholamines; Cerebellum; Coturnix; Diencephalon; Dopamine; Hydroxyindoleacetic Acid; Male; Neurotransmitter Agents; Norepinephrine; Optic Lobe, Nonmammalian; Quail; Serotonin; Testosterone; Tryptophan | 1984 |
Raman spectroscopic study of age-related structural changes in the lens proteins of an intact mouse lens.
Topics: Aging; Animals; Body Water; Crystallins; Disulfides; Lens, Crystalline; Mice; Mice, Inbred ICR; Protein Conformation; Spectrum Analysis, Raman; Tryptophan; Tyrosine | 1983 |
Lifespan and protein synthesis in several Bombyx mori mutants with genetic abnormalities in amino acid and protein metabolism.
Topics: Aging; Animals; Bombyx; Female; Fibroins; Longevity; Male; Peptides, Cyclic; Sericins; Tryptophan | 1983 |
Photolytic changes in lens proteins.
Topics: Adolescent; Aged; Aging; Animals; Cataract; Cattle; Crystallins; Glucosides; Humans; In Vitro Techniques; Kynurenine; Lens, Crystalline; Photochemistry; Photolysis; Tryptophan | 1984 |
Tryptophan availability: the importance of prepartum and postpartum dietary protein on brain indoleamine metabolism in rats.
Topics: Aging; Animals; Animals, Newborn; Birth Weight; Brain; Dietary Proteins; Female; Hydroxyindoleacetic Acid; Lactation; Maternal-Fetal Exchange; Organ Size; Pregnancy; Protein-Energy Malnutrition; Rats; Serotonin; Tryptophan | 1980 |
Senile amyloid deposition.
Topics: Aged; Aging; Amyloid; Aorta; Arteries; Female; Histocytochemistry; Humans; Male; Myocardium; Potassium Permanganate; Sex Factors; Tissue Distribution; Tryptophan | 1983 |
Amyloid of the seminal vesicles. A distinctive and common localized form of senile amyloidosis.
Topics: Aged; Aging; Amyloid; Amyloidosis; Autopsy; Histocytochemistry; Humans; Male; Middle Aged; Seminal Vesicles; Serum Amyloid P-Component; Tryptophan | 1983 |
Developmental modulations of blood-brain barrier permeability as an indicator of changing nutritional requirements in the brain.
Topics: Adenine; Aging; Animals; Animals, Newborn; Arginine; Blood-Brain Barrier; Brain; Butanols; Choline; Glucose; Lactates; Permeability; Rabbits; Tryptophan | 1982 |
Effect of exposure to light in enzyme activities and tryptophan metabolites of the kynurenine pathway in Wistar, in heterozygous and homozygous adult and newborn Gunn rats.
Topics: Aging; Animals; Animals, Newborn; Female; Heterozygote; Hydrolases; Kynurenine; Light; Liver; Lyases; Male; Rats; Rats, Inbred Strains; Species Specificity; Transaminases; Tryptophan; Tryptophan Oxygenase | 1982 |
A note on the amino acid composition of the turkey.
Topics: Aging; Amino Acids; Animals; Autoanalysis; Body Composition; Chickens; Cystine; Feathers; Geese; Male; Methionine; Proteins; Species Specificity; Tryptophan; Turkeys | 1982 |
Xanthurenic acid excretion in urine after oral intake of 5 grams L-tryptophan by healthy volunteers: standardisation of the reference values.
Topics: Aging; Body Height; Body Weight; Creatinine; Humans; Hydrogen-Ion Concentration; Reference Values; Sex Factors; Tryptophan; Xanthurenates | 1981 |
Effects of long-term low dietary tryptophan intake on determinants of 5-hydroxytryptamine metabolism in the brains of young rats.
Topics: Aging; Animals; Body Weight; Brain; Rats; Serotonin; Tryptophan | 1981 |
In vivo deacetylation of N-acetyl amino acids by kidney acylases in mice and rats. A possible role of acylase system in mammalian kidneys.
Topics: Aging; Amidohydrolases; Animals; Histidine; Kidney; Kinetics; Liver; Mice; Rats; Tissue Distribution; Tryptophan | 1980 |
Diet and increased life span.
Topics: Aging; Animals; Cholesterol; Diet; Feeding Behavior; Humans; Longevity; Proteins; Tryptophan | 1980 |
Effects of age and substrate on the circadian rhythm of liver tryptophan pyrrolase of female rats.
Topics: Aging; Animals; Circadian Rhythm; Enzyme Induction; Female; Liver; Rats; Reproduction; Tryptophan; Tryptophan Oxygenase | 1980 |
Tryptophan transport by isolated newborn rabbit jejunum.
Topics: Aging; Alanine; Animals; Animals, Newborn; Intestinal Absorption; Jejunum; Phenylalanine; Rabbits; Sodium; Tryptophan | 1980 |
Effect of aging on the kinetics of blood-brain barrier uptake of tryptophan in rats.
Topics: Aging; Animals; Biological Transport, Active; Blood-Brain Barrier; Brain; Cell Membrane Permeability; Diffusion; Rats; Rats, Sprague-Dawley; Tryptophan | 1995 |
Photodegradation of tryptophan residues and attenuation of molecular chaperone activity in alpha-crystallin are correlated.
Topics: Aging; Animals; Cataract; Crystallins; Hot Temperature; Humans; In Vitro Techniques; Molecular Chaperones; Photochemistry; Protein Conformation; Rabbits; Spectrometry, Fluorescence; Tryptophan; Ultraviolet Rays | 1995 |
Serotonin involvement in the spontaneous alternation ability: a behavioral study in tryptophan-restricted rats.
Topics: Aging; Animals; Body Weight; Diet; Exploratory Behavior; Female; Rats; Rats, Sprague-Dawley; Serotonin; Tryptophan | 1995 |
Tonic immobility and high-intensity calls in a precocial chick as a function of age, diet, and time of day.
Topics: Aging; Animals; Arousal; Chickens; Circadian Rhythm; Female; Immobilization; Male; Motor Activity; Neural Inhibition; Serotonin; Social Environment; Tryptophan; Vocalization, Animal | 1994 |
Glutathione levels of the human crystalline lens in aging and its antioxidant effect against the oxidation of lens proteins.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Antioxidants; Cataract; Child; Chromatography, High Pressure Liquid; Circular Dichroism; Crystallins; Glutathione; Glutathione Reductase; Humans; Lens, Crystalline; Middle Aged; Oxidation-Reduction; Protein Binding; Thiobarbituric Acid Reactive Substances; Tryptophan; Tyrosine | 1993 |
Local variations in protein structure in the human eye lens: a Raman microspectroscopic study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Crystallins; Eye Proteins; Humans; Lens, Crystalline; Microchemistry; Middle Aged; Phenylalanine; Protein Conformation; Spectrum Analysis, Raman; Tryptophan; Tyrosine | 1993 |
High levels of quinolinic acid in brain of epilepsy-prone E1 mice.
Topics: Aging; Amino Acids; Animals; Cerebral Cortex; Epilepsy; Escherichia coli; Lipopolysaccharides; Methionine; Mice; Mice, Inbred Strains; Mice, Neurologic Mutants; Quinolinic Acid; Species Specificity; Threonine; Tryptophan | 1993 |
Neuroamine related compounds in the CSF of hydrocephalic rabbits.
Topics: Aging; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Homovanillic Acid; Hydrocephalus; Hydroxyindoleacetic Acid; Rabbits; Tryptophan; Tyrosine | 1995 |
Susceptibility of gamma-irradiated proteins to in vitro glycation: exposure to oxygen free radicals increases glycation-induced modifications.
Topics: Aging; Dose-Response Relationship, Radiation; Fluorescent Dyes; Free Radicals; Gamma Rays; Glucose; Glycosylation; Oxidation-Reduction; Protein Conformation; Reactive Oxygen Species; Serum Albumin, Bovine; Tryptophan | 1996 |
Chronic tryptophan restriction disrupts grooming chain completion in the rat.
Topics: Aging; Animals; Brain Chemistry; Diet; Emotions; Female; Grooming; Motor Activity; Rats; Rats, Wistar; Serotonin; Tryptophan | 1996 |
The performance of commercial broilers when fed various levels of rendered whole-hen meal.
Topics: Aging; Animal Feed; Animals; Arginine; Body Weight; Chickens; Diet; Eating; Food Handling; Food Preservation; Tryptophan | 1996 |
Effects of immune challenge, dietary energy density, and source of energy on performance and immunity in weanling pigs.
Topics: Aging; Animal Nutritional Physiological Phenomena; Animals; Antibodies; Cell Division; Dietary Fats; Energy Intake; Energy Metabolism; Escherichia coli; Female; Lipopolysaccharides; Lymphocytes; Lysine; Male; Swine; Threonine; Tryptophan; Weight Gain | 1996 |
Age dependence of large neutral amino acid levels in plasma. Focus on Tryptophan.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aging; Amino Acids; Female; Humans; Male; Middle Aged; Sex Factors; Tryptophan | 1996 |
Age-related accumulation of 1-methyl-1,2,3,4-tetrahydro-beta-carboline-3- carboxylic acid in human lens.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Carbolines; Cataract; Chromatography, High Pressure Liquid; Glucose; Hot Temperature; Humans; In Vitro Techniques; Lens, Crystalline; Middle Aged; Tryptophan | 1996 |
Modification of protein surface hydrophobicity and methionine oxidation by oxidative systems.
Topics: Aging; Animals; Methionine; Oxidation-Reduction; Proteins; Rats; Rats, Inbred F344; Tryptophan; Tyrosine | 1997 |
Marginal efficiency of free or protected crystalline L-tryptophan for tryptophan and protein accretion in early-weaned pigs.
Topics: Aging; Amino Acids; Animals; Crystallization; Diet; Female; Male; Nitrogen; Proteins; Swine; Tryptophan | 1997 |
Effect of tryptophan restriction on short-term memory.
Topics: Aging; Animals; Body Weight; Brain; Diet; Female; Maze Learning; Memory, Short-Term; Organ Size; Rats; Rats, Sprague-Dawley; Serotonin; Tryptophan | 1998 |
Tryptophan ingestion by gestant mothers alters prolactin and luteinizing hormone release in the adult male offspring.
Topics: Aging; Animals; Animals, Newborn; Female; Gestational Age; Luteinizing Hormone; Male; Pregnancy; Prenatal Exposure Delayed Effects; Prolactin; Rats; Rats, Sprague-Dawley; Sex Characteristics; Tryptophan | 1997 |
The aggregation in human lens proteins blocks the scavenging of UVA-generated singlet oxygen by ascorbic acid and glutathione.
Topics: Aging; Antioxidants; Ascorbic Acid; Crystallins; Cysteine; Fluorescence; Free Radical Scavengers; Glutathione; Histidine; Humans; Peroxides; Photolysis; Protein Conformation; Protein Denaturation; Reactive Oxygen Species; Sodium Azide; Tryptophan; Ultraviolet Rays; Urea | 1998 |
Progressive decline in the ability of calmodulin isolated from aged brain to activate the plasma membrane Ca-ATPase.
Topics: Aging; Amino Acid Sequence; Animals; Brain Chemistry; Calcium; Calcium-Transporting ATPases; Calmodulin; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Erythrocyte Membrane; Mass Spectrometry; Methionine; Molecular Sequence Data; Oxidation-Reduction; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Secondary; Rats; Rats, Inbred F344; Spectrometry, Fluorescence; Swine; Thermodynamics; Tryptophan; Tyrosine | 1998 |
The Trp64Arg polymorphism of the beta 3-adrenergic receptor gene is not associated with obesity or type 2 diabetes mellitus in a large population-based Caucasian cohort.
Topics: Adult; Aging; Alleles; Arginine; Body Mass Index; Body Temperature Regulation; Body Weight; Cholesterol; Cohort Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Energy Metabolism; Female; Genotype; Humans; Lipolysis; Male; Middle Aged; Obesity; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Random Allocation; Receptors, Adrenergic, beta; Tryptophan | 1998 |
Serotonin-immune interactions in elderly volunteers and in patients with Alzheimer's disease (DAT): lower plasma tryptophan availability to the brain in the elderly and increased serum interleukin-6 in DAT.
Topics: Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Brain; Case-Control Studies; Female; Humans; Interleukin-6; Interleukin-8; Male; Middle Aged; Serotonin; Tryptophan | 1998 |
Age-dependent changes in memory and mushroom bodies in the Drosophila mutant vermilion deficient in the kynurenine pathway of tryptophan metabolism.
Topics: Aging; Animals; Brain; Conditioning, Classical; Drosophila; Kynurenine; Memory; Mutation; Sexual Behavior, Animal; Tryptophan | 1999 |
Changes in nocturnal pineal melatonin synthesis during the perimenopausal period: relation to estrogen levels in female rats.
Topics: Acetylserotonin O-Methyltransferase; Aging; Animals; Arylamine N-Acetyltransferase; Circadian Rhythm; Darkness; Estradiol; Female; Melatonin; Norepinephrine; Pineal Gland; Rats; Rats, Sprague-Dawley; Tryptophan | 1999 |
UV filter compounds in human lenses: the origin of 4-(2-amino-3-hydroxyphenyl)-4-oxobutanoic acid O-beta-D-glucoside.
Topics: Acrylates; Adult; Aging; Benzoates; Chromatography, High Pressure Liquid; Deamination; Fetus; Glucosides; Humans; Hydrogen-Ion Concentration; Infant; Kynurenine; Lens, Crystalline; Middle Aged; Phenylbutyrates; Propionates; Tryptophan; Ultraviolet Rays | 1999 |
The Nitrite/alpha crystallin reaction: a possible mechanism in lens matrix damage.
Topics: Aging; Animals; Cataract; Cattle; Chromatography, High Pressure Liquid; Crystallins; Electrophoresis, Polyacrylamide Gel; Humans; Kynurenine; Lens, Crystalline; Nitrites; Oxidation-Reduction; Smoking; Spectrophotometry, Ultraviolet; Tryptophan; Ultraviolet Rays | 2000 |
Where does indolylacrylic acid come from?
Topics: Aging; Burns; Diet; Glycine; Humans; Indoles; Muscular Dystrophies; Skin Diseases; Tryptophan; Urinary Bladder Neoplasms | 1999 |
Effects of long-term parenteral administration of vitamin B6 on B6 status and some aspects of the glucose and protein metabolism of early-weaned piglets.
Topics: Aging; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Blood Glucose; Body Composition; Diet; Dietary Supplements; Dose-Response Relationship, Drug; Female; Injections, Intramuscular; Male; Pyridoxal Phosphate; Pyridoxine; Swine; Tryptophan; Weaning; Weight Gain | 2001 |
Developmental changes in cerebrospinal fluid concentrations of monoamine-related substances in patients with dentatorubral-pallidoluysian atrophy.
Topics: Adolescent; Age Factors; Aging; Biogenic Monoamines; Case-Control Studies; Child; Child, Preschool; Chromatography, High Pressure Liquid; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Myoclonic Epilepsies, Progressive; Tryptophan; Tyrosine | 2001 |
Tryptophan requirements of different broiler genotypes.
Topics: Aging; Animals; Body Composition; Body Weight; Chickens; Crosses, Genetic; Dietary Supplements; Dose-Response Relationship, Drug; Energy Intake; Female; Genotype; Male; Nutritional Requirements; Sex Characteristics; Tryptophan; Weight Gain | 2001 |
Effects of methylmercury on brain biogenic amines in the developing rat pup.
Topics: Aging; Animals; Animals, Newborn; Biogenic Amines; Brain; Dopamine; Hydroxyindoleacetic Acid; Methylmercury Compounds; Monoamine Oxidase; Norepinephrine; Rats; Serotonin; Time Factors; Tryptophan; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase | 1976 |
Long-term tryptophan restriction and aging in the rat.
Topics: Aging; Animal Feed; Animals; Diet; Life Expectancy; Rats; Time Factors; Tryptophan | 1977 |
Kainic acid alters neurochemical development in fetal rat brain aggregating cell cultures.
Topics: Acetylcholinesterase; Aging; Animals; Brain; Cell Aggregation; Choline O-Acetyltransferase; Cyclic GMP; Dopa Decarboxylase; Dose-Response Relationship, Drug; Glutamate Decarboxylase; Kainic Acid; Monoamine Oxidase; Neurons; Organ Culture Techniques; Pyrrolidines; Rats; Tryptophan; Tyrosine 3-Monooxygenase | 1977 |
[On molecular biology of aging. 11th communication. Enzyme adaptation, age (author's transl)].
Topics: Adaptation, Biological; Aging; Aldehyde Oxidoreductases; Animals; Enzymes; Glucokinase; Glucosephosphate Dehydrogenase; Isoenzymes; Liver; Molecular Biology; Ornithine-Oxo-Acid Transaminase; Oxygenases; Phosphofructokinase-1; Pyruvate Kinase; Rats; Starvation; Tryptophan; Tyrosine Transaminase | 1977 |
[Investigations on the plasm amino acids of old patients with rheumatoid arthritis (author's transl)].
Topics: Aged; Aging; Amino Acids; Arginine; Arthritis, Rheumatoid; Chromatography, Ion Exchange; Cystathionine; Humans; Methylhistidines; Middle Aged; Threonine; Tryptophan | 1977 |
Brain tryptophan metabolism in schizophrenia: a post mortem study of metabolites of the serotonin and kynurenine pathways in schizophrenic and control subjects.
Topics: Aged; Aging; Brain; Female; Humans; Hydroxyindoleacetic Acid; Kynurenine; Male; Middle Aged; Myocardial Infarction; Postmortem Changes; Schizophrenia; Serotonin; Sex Factors; Tryptophan | 1979 |
Evidence for a free radical mechanism in aging and u.v.-irradiated ocular lenses.
Topics: Aging; Animals; Cataract; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Lens, Crystalline; Penicillamine; Rats; Tryptophan; Ultraviolet Rays | 1977 |
The contribution of tryptophan to the regulation of the NAD+ level in mouse liver.
Topics: Aging; Animals; Liver; Mice; NAD; Niacinamide; Nicotinic Acids; Organ Specificity; Tryptophan | 1975 |
Ontogenesis of tryptophan transport in the rat brain.
Topics: Aging; Animals; Animals, Newborn; Biological Transport, Active; Blood-Brain Barrier; Brain; Rats; Serotonin; Serum Albumin; Tryptophan | 1979 |
Age related changes in the effect of electroconvulsive shock (ECS) on the in vivo hydroxylation of tyrosine and tryptophan in rat brain.
Topics: 5-Hydroxytryptophan; Aging; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benzyl Alcohols; Brain; Dihydroxyphenylalanine; Electroshock; Hydrazines; Male; Rats; Tryptophan; Tyrosine | 1977 |
Metabolic stability of nonhistone chromosomal proteins in two different classes of developing rat brain nuclei.
Topics: Aging; Animals; Brain; Cell Nucleus; Chromosomal Proteins, Non-Histone; DNA; Rats; Thymidine; Tryptophan | 1979 |
Melatonin in human cerebrospinal fluid in daytime; its origin and variation with age.
Topics: Adolescent; Adult; Aged; Aging; Child; Female; Humans; Hydroxyindoleacetic Acid; Male; Melatonin; Middle Aged; Time Factors; Tryptophan | 1979 |
Effects of reduction on absorption and fluorescence of human lens protein.
Topics: Aging; Cataract; Crystallins; Humans; Oxidation-Reduction; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tryptophan | 1979 |
The effect of age on the protein degradation system in the nematode Turbatrix aceti.
Topics: Aging; Animals; Canavanine; Fructose-Bisphosphate Aldolase; Hot Temperature; Nematoda; Proteins; Tryptophan | 1979 |
Hypothermia in the aged.
Topics: Aging; Cold Temperature; Diet; Humans; Hypothermia; Hypothyroidism; Shivering; Tryptophan; Vasoconstriction | 1977 |
Post-natal changes in the transport of aromatic amino acids into the brain [proceedings].
Topics: Aging; Amino Acids; Animals; Biological Transport; Brain; Phenylalanine; Rats; Tryptophan; Tyrosine | 1978 |
Histochemical study on systemic amyloid microdeposits with special reference to parathyroid intrafollicular deposits.
Topics: Aged; Aging; Amyloid; Benzaldehydes; Congo Red; Female; Histocytochemistry; Humans; Male; Microscopy, Fluorescence; Middle Aged; Parathyroid Glands; Tryptophan | 1975 |
Testing the protein error hypothesis of ageing in Drosophila.
Topics: Aging; Animals; Drosophila melanogaster; Ethionine; Half-Life; Male; Phenylalanine; Proteins; Tryptophan; Tyrosine | 1976 |
Tryptophan and 5-hydroxytryptamine metabolism in the immature rat brain during recovery from asphyxia.
Topics: Aging; Animals; Asphyxia; Blood Proteins; Brain; Brain Chemistry; Female; Hydroxyindoleacetic Acid; Male; Protein Binding; Rats; Serotonin; Tryptophan; Tyrosine | 1977 |
Immunoengineering may increase longevity.
Topics: Aging; Animals; Body Temperature; Energy Intake; Graft Rejection; Humans; Immunity; Lymphocytes; Mice; Mice, Inbred C57BL; Mitogens; Protein Deficiency; Tryptophan | 1977 |
Acute changes in central serotonin metabolism induced by the blockade or stimulation of serotoninergic receptors during ontogenesis in the rat.
Topics: Adenylyl Cyclases; Aging; Animals; Animals, Newborn; Brain; Female; Hydroxyindoleacetic Acid; In Vitro Techniques; Lysergic Acid Diethylamide; Male; Methiothepin; Monoamine Oxidase; Potassium; Rats; Receptors, Serotonin; Serotonin; Tryptophan | 1977 |
Experimental studies on cataract.
Topics: Aging; Animals; Ascorbic Acid; Cataract; Crystallins; Diabetic Retinopathy; Humans; Lens, Crystalline; Naphthalenes; Naphthoquinones; Peptide Hydrolases; Sorbitol; Tryptophan | 1976 |
What nutritional deprivation experiments reveal about aging.
Topics: Aging; Animals; Dietary Carbohydrates; Dietary Fats; Humans; Longevity; Models, Biological; Rats; Tryptophan | 1976 |
Age-related changes in the thermoregulatory capacity of tryptophan-deficient rats.
Topics: Age Factors; Aging; Animals; Biological Clocks; Body Temperature Regulation; Body Weight; Brain; Cold Temperature; Diet; Growth; Homeostasis; Immersion; Models, Biological; Rats; Serotonin; Tryptophan | 1975 |
Effects of hydrocortisone and immobilization on tryptophan metabolism in brain and liver of rats of different ages.
Topics: Aging; Animals; Brain; Enzyme Induction; Female; Hydrocortisone; Hydroxyindoleacetic Acid; Immobilization; Liver; Male; Rats; Serotonin; Tryptophan; Tryptophan Oxygenase | 1975 |
Isolation and characterization of an age-dependent polypeptide from human lens with non-tryptophan fluorescence.
Topics: Adolescent; Adult; Aged; Aging; Amino Acids; Child; Child, Preschool; Chromatography, Ion Exchange; Crystallins; Electrophoresis, Paper; Fluorescence; Glycine; Humans; Hydrolysis; Infant; Middle Aged; Molecular Weight; Peptides; Proline; Spectrophotometry; Tryptophan | 1975 |
The effect of age on protein synthesis and ribosome aggregation to messenger RNA in rat liver.
Topics: Aging; Amino Acids; Animals; Binding Sites; Female; Kinetics; Liver; Microsomes, Liver; Polyribosomes; Protein Biosynthesis; Rats; Ribosomes; RNA, Messenger; Subcellular Fractions; Tryptophan | 1976 |
Tryptophan and serotonin metabolism in familial erythrophagocytic lymphohistiocytosis.
Topics: Aging; Amino Acids; Biopterins; Child, Preschool; Etoposide; Histiocytosis, Non-Langerhans-Cell; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Male; Methotrexate; Neopterin; Prednisolone; Serotonin; Tryptophan | 1992 |
[Age changes in concentrations of monoamines and related substances in the cerebrospinal fluid].
Topics: Adolescent; Adult; Aged; Aging; Biogenic Monoamines; Child; Chromatography, High Pressure Liquid; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Middle Aged; Neurotransmitter Agents; Norepinephrine; Tryptophan; Tyrosine | 1991 |
Lung concentrations of 5-hydroxytryptamine, tryptophan, 5-hydroxytryptophan and 5-hydroxyindole acetic acid in rats of different ages.
Topics: 5-Hydroxytryptophan; Aging; Animals; Hydroxyindoleacetic Acid; Lung; Male; Organ Size; Rats; Rats, Inbred Strains; Serotonin; Tryptophan | 1991 |
Tryptophan metabolism in senile cataract patients assessed by high-performance liquid chromatography.
Topics: Aging; Cataract; Chromatography, High Pressure Liquid; Humans; Kynurenic Acid; Kynurenine; Tryptophan | 1991 |
Persistent protein damage despite reduced oxygen radical formation in the aging rat brain.
Topics: Aging; Animals; Ascorbic Acid; Brain; Cerebral Cortex; Ferric Compounds; Fluoresceins; Free Radicals; In Vitro Techniques; Male; Nerve Tissue Proteins; Oxygen Consumption; Rats; Rats, Inbred F344; Superoxide Dismutase; Tryptophan | 1991 |
The therapeutic potential for tryptophan and melatonin: possible roles in depression, sleep, Alzheimer's disease and abnormal aging.
Topics: Aging; Animals; Bipolar Disorder; Dementia; Depressive Disorder; Humans; Melatonin; Mental Disorders; Sleep Wake Disorders; Tryptophan | 1990 |
Front surface fluorescence measurements of the age-related change in the human lens.
Topics: Aged; Aging; Animals; Cattle; Crystallins; Fluorescence; Humans; Lens, Crystalline; Methods; Middle Aged; Tryptophan | 1990 |
Degradation of crystallins from a psoriatic patient undergoing PUVA therapy.
Topics: Aging; Cataract; Crystallins; Eye Proteins; Humans; Lens, Crystalline; Molecular Weight; Psoriasis; PUVA Therapy; Solubility; Spectrometry, Fluorescence; Tryptophan | 1990 |
Blood serotonin and tryptophan in Tourette syndrome.
Topics: Adult; Aging; Attention Deficit Disorder with Hyperactivity; Child; Cloning, Molecular; Fasting; Female; Homozygote; Humans; Intestines; Liver; Male; Mental Disorders; Platelet Count; Serotonin; Sex Factors; Tourette Syndrome; Tryptophan; Tryptophan Oxygenase | 1990 |
HPLC assays of 5-HIAA and tryptophan in cerebrospinal fluid and 5-HT and tryptophan in blood: a methodological study with clinical applications.
Topics: Adult; Aging; Antidepressive Agents, Tricyclic; Blood Platelets; Chromatography, High Pressure Liquid; Depressive Disorder; Female; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Serotonin; Sex Factors; Tryptophan | 1988 |
Photoreactions of human lens monomeric crystallins.
Topics: Adolescent; Adult; Aging; Crystallins; Fetus; Humans; Hydrogen Peroxide; Infant; Kinetics; Lens, Crystalline; Middle Aged; Molecular Weight; Photochemistry; Spectrometry, Fluorescence; Spectrophotometry; Superoxides; Tryptophan | 1989 |
[The effect of sodium ions on amino acid and peptide assimilation in the small intestine of developing chicks].
Topics: Aging; Amino Acids; Animals; Chickens; Dipeptides; Glycine; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Peptides; Sodium; Tryptophan | 1989 |
Fluorescence studies on the age related changes in bovine and human lens membrane structure.
Topics: Adult; Aged; Aging; Anilino Naphthalenesulfonates; Animals; Cattle; Diphenylhexatriene; Electrophoresis, Polyacrylamide Gel; Fluorescence; Humans; Lens, Crystalline; Membranes; Middle Aged; Spectrometry, Fluorescence; Tryptophan | 1989 |
Neurotransmitter precursors and brain function.
Topics: Aged; Aging; Alzheimer Disease; Animals; Biological Transport; Brain; Diet; Humans; Learning; Levodopa; Memory; Neurotransmitter Agents; Parkinson Disease; Phosphatidylcholines; Serotonin; Sleep; Tryptophan | 1986 |
The physiopathological role of quinolinic acid in the mammalian central nervous system.
Topics: Aging; Alzheimer Disease; Animals; Cerebral Cortex; Gas Chromatography-Mass Spectrometry; Hepatic Encephalopathy; Humans; Liver; Liver Cirrhosis; Male; Portacaval Shunt, Surgical; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Tryptophan | 1988 |
Brain serotonin synthesis and Na+,K+-ATPase activity are increased postnatally after prenatal administration of L-tryptophan.
Topics: Aging; Animals; Animals, Newborn; Cerebral Cortex; Female; Injections, Intraperitoneal; Maternal-Fetal Exchange; Pregnancy; Rats; Rats, Inbred Strains; Serotonin; Sodium-Potassium-Exchanging ATPase; Tryptophan; Tryptophan Hydroxylase | 1986 |
Further studies on the nutritional factors affecting the urinary excretion of acid-soluble peptides in rats.
Topics: Aging; Amino Acids; Animals; Caseins; Dietary Proteins; Leucine; Lysine; Male; Methylhistidines; Nitrogen; Peptides; Proline; Rats; Rats, Inbred Strains; Tryptophan; Valine | 1988 |
Raman spectroscopic evaluation of aging and long-wave UV exposure in the guinea pig lens: a possible model for human aging.
Topics: Aging; Animals; Disulfides; Guinea Pigs; Lens, Crystalline; Phenylalanine; Protein Conformation; Spectrum Analysis, Raman; Sulfhydryl Compounds; Tryptophan; Tyrosine; Ultraviolet Rays | 1988 |
Effect of aging on intestinal absorption of aromatic amino acids in vitro in the rat.
Topics: Aging; Animals; In Vitro Techniques; Intestinal Absorption; Jejunum; Kinetics; Male; Phenylalanine; Rats; Rats, Inbred F344; Tryptophan; Tyrosine | 1988 |
Acrylamide and iodide fluorescence quenching studies on whole human lenses and their protein extracts.
Topics: Acrylamide; Acrylamides; Adolescent; Adult; Aged; Aging; Child; Child, Preschool; Crystallins; Fluorescence; Humans; Iodides; Lens, Crystalline; Magnetic Resonance Spectroscopy; Middle Aged; Tryptophan; Ultraviolet Rays | 1988 |
Histology and survival in age-delayed low-tryptophan-fed rats.
Topics: Aging; Animals; Body Weight; Brain; Female; Longevity; Rats; Serotonin; Tryptophan | 1988 |
Measures of leucine aminopeptidase can be used to anticipate UV-induced age-related damage to lens proteins: ascorbate can delay this damage.
Topics: Aging; Animals; Ascorbic Acid; Crystallins; Kinetics; Lens, Crystalline; Leucyl Aminopeptidase; Rabbits; Spectrometry, Fluorescence; Tryptophan; Ultraviolet Rays | 1987 |
The maturational onset of the 5-HT mediated head twitch in mice.
Topics: 5-Hydroxytryptophan; Aging; Animals; Carbidopa; Female; Humans; Male; Mice; Motor Activity; Pargyline; Serotonin; Tryptophan | 1987 |
Tryptophan Raman/457.9-nm-excited fluorescence of intact guinea pig lenses in aging and ultraviolet light.
Topics: Aging; Animals; Guinea Pigs; Lens, Crystalline; Photolysis; Spectrometry, Fluorescence; Spectrum Analysis, Raman; Tryptophan; Ultraviolet Rays | 1987 |
Plasma tryptophan and total neutral amino acid levels in men: influence of hyperinsulinemia and age.
Topics: Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Brain; Humans; Hyperinsulinism; Male; Serotonin; Tryptophan | 1987 |
Distribution of aromatic and fluorescent compounds within single human lenses.
Topics: Adult; Aged; Aged, 80 and over; Aging; Cataract; Chromatography, High Pressure Liquid; Fluorescence; Humans; Lens, Crystalline; Middle Aged; Tryptophan; Tyrosine; Uric Acid | 1987 |
Effect of aging on plasma tryptophan.
Topics: Aged; Aging; Female; Humans; Male; Middle Aged; Tryptophan | 1986 |
Influence of low tryptophan diet on survival and organ growth in mice.
Topics: Aging; Animals; Body Weight; Diet; DNA; Longevity; Male; Mice; Organ Size; Tissue Distribution; Tryptophan | 1986 |
The change with age in biogenic amines and their metabolites in the striatum of the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Aging; Animals; Biogenic Amines; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin; Tryptophan | 1986 |
Rate of tryptophan hydroxylation in vivo in brain nuclei of genetically hypertensive rats of the Lyon strain.
Topics: 5-Hydroxytryptophan; Aging; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Hydrazines; Hydroxylation; Hypertension; Hypothalamus; Medulla Oblongata; Raphe Nuclei; Rats; Rats, Mutant Strains; Tryptophan | 1985 |
Influence of diet on plasma tryptophan and brain serotonin levels in mice.
Topics: Aging; Animals; Brain; Dietary Proteins; Male; Mice; Serotonin; Tryptophan | 1985 |
Plasma tryptophan, age and depression.
Topics: Adolescent; Adult; Aged; Aging; Depression; Female; Humans; Male; Middle Aged; Serum Albumin; Tryptophan | 1985 |
Ontogenetic studies on tryptophan transport into plasma membrane vesicles derived from rat brain synaptosomes: effect of thyroid hormones.
Topics: Aging; Animals; Aspartic Acid; Biological Transport; Brain; Cell Membrane; Kinetics; Osmolar Concentration; Rats; Rats, Inbred Strains; Sodium; Synaptosomes; Triiodothyronine; Tryptophan | 1985 |
Age-related changes in protein conformation in bovine lens crystallins.
Topics: Absorption; Aging; Anilino Naphthalenesulfonates; Animals; Cattle; Circular Dichroism; Crystallins; Female; Fluorescence; Protein Conformation; Spectrum Analysis; Sulfhydryl Compounds; Tryptophan | 1985 |
[Quantitative cytochemistry of the inner ear of the young and senile guinea pig].
Topics: Aging; Animals; Ear, Inner; Guinea Pigs; Histocytochemistry; Microscopy; Organ of Corti; Photometry; Proteins; RNA; Staining and Labeling; Tritium; Tryptophan; Tyrosine; Ultraviolet Rays | 1970 |
Amyloid in normal and pathological parathyroid glands.
Topics: Aging; Amyloid; Amyloidosis; Autopsy; Histocytochemistry; Humans; Parathyroid Glands; Staining and Labeling; Thyroidectomy; Tryptophan; Tyrosine | 1974 |
The biosynthesis and degradation of nicotinamide-adenine dinucleotide during cick embryonic development.
Topics: Aging; Animals; Carbon Isotopes; Chick Embryo; N-Glycosyl Hydrolases; NAD; Niacinamide; Nicotinic Acids; Phosphoric Monoester Hydrolases; Tryptophan | 1969 |
Nicotinamide adenine dinucleotide in developing chick embryo.
Topics: Aging; Alcohol Oxidoreductases; Animals; Chick Embryo; Egg White; Egg Yolk; Female; Hydrogen-Ion Concentration; Liver; NAD; Niacinamide; Nicotinic Acids; Ovalbumin; Pyridines; Tryptophan | 1971 |
Aromatic amino acid metabolism in the wabbler-lethal mouse.
Topics: Aging; Animals; Liver; Mice; Mixed Function Oxygenases; Nervous System Diseases; Phenylalanine; Rodent Diseases; Transaminases; Tryptophan; Tryptophan Oxygenase; Tyrosine; Tyrosine Transaminase | 1969 |
The postnatal induction of serine dehydratase in rat liver.
Topics: Aging; Animals; Animals, Newborn; Butyrates; Cyclic AMP; Cycloheximide; Dactinomycin; Drug Antagonism; Enzyme Induction; Enzyme Repression; Epinephrine; Female; Glucagon; Glucose; L-Serine Dehydratase; Liver; Pregnancy; Rats; Tryptophan | 1971 |
Plasma tryptophan and 5-HT metabolism in the CNS of the newborn rat.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Biological Transport; Blood-Brain Barrier; Brain; Brain Stem; Chlordiazepoxide; Chromatography, Gel; Chromatography, Ion Exchange; Female; Hydroxyindoleacetic Acid; In Vitro Techniques; Kinetics; Male; Organ Specificity; Pregnancy; Rats; Salicylates; Serotonin; Time Factors; Tritium; Tryptophan; Tyrosine; Ultrafiltration | 1974 |
Guinea-pig liver tryptophan pyrrolase. Absence of detectable apoenzyme activity and of hormonal induction by cortisol and possible regulation by tryptophan.
Topics: Aging; Allopurinol; Animals; Apoproteins; Cycloheximide; Dactinomycin; Enzyme Induction; Enzyme Precursors; Guinea Pigs; Hydrocortisone; Injections, Intraperitoneal; Kynurenine; Liver; Male; Rats; Tryptophan; Tryptophan Oxygenase | 1974 |
Intestinal absorption of some heterocyclic and aromatic amino acids from the ageing gut.
Topics: Aging; Animals; Biological Transport; Carbon Radioisotopes; Female; Intestinal Absorption; Intestine, Small; Kinetics; Liver; Organ Size; Phenylalanine; Proline; Rats; Tryptophan | 1974 |
Intestinal absorption of aromatic amino acids in senescence.
Topics: Aging; Amino Acids; Animals; Indicator Dilution Techniques; Intestinal Absorption; Phenylalanine; Protein-Losing Enteropathies; Rats; Tryptophan | 1972 |
[Amino acid absorption in the aged].
Topics: Age Factors; Aging; Amino Acids; Animals; Carbohydrate Metabolism; Female; Intestinal Absorption; Phenylalanine; Rats; Tryptophan; Vitamins | 1973 |
Uncorporation of phenylalanine as a single unit into rat brain protein: reciprocal inhibition by phenylalanine and tyrosine of their respective incorporations.
Topics: Adenosine Triphosphate; Aging; Animals; Asparagine; Brain; Carbon Radioisotopes; Glutamates; Glutamine; Histidine; In Vitro Techniques; Kidney; Kinetics; Liver; Magnesium; Methionine; Nerve Tissue Proteins; Phenylalanine; Potassium; Rats; Thyroid Gland; Tritium; Tryptophan; Tyrosine | 1973 |
[Biochemical studies on the age-related variations of the human intervertebral disc].
Topics: Adolescent; Adult; Aged; Aging; Child; Child, Preschool; Chromatography; Collagen; Galactosamine; Glucosamine; Hexosamines; Humans; Infant; Intervertebral Disc; Lumbar Vertebrae; Middle Aged; Phenylalanine; Potassium; Sodium; Thoracic Vertebrae; Tryptophan; Tyrosine | 1972 |
Molecular basis for multiplicity of Pacific salmon hemoglobins: evidence for in vivo existence of molecular species with up to four different polypeptides.
Topics: Aging; Amino Acids; Animals; Carbon Monoxide; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Paper; Cyanides; Electrophoresis; Electrophoresis, Paper; Ferricyanides; Genes; Hemoglobins; Heterozygote; Hybridization, Genetic; Hydrogen-Ion Concentration; Macromolecular Substances; Methemoglobin; Oxidation-Reduction; Peptides; Potassium; Protein Binding; Salmon; Species Specificity; Spectrophotometry; Starch; Trypsin; Tryptophan | 1971 |
Eye lens color: formation and function.
Topics: Aging; Aminobenzoates; Animals; Cataract; Crystallins; Eye Proteins; Fluorescence; Lens, Crystalline; Photochemistry; Pigments, Biological; Radiation Effects; Sharks; Spectrophotometry; Tryptophan; Ultraviolet Rays | 1971 |
Turnover of tryptophan-induced tryptophan pyrrolase in rat liver as a function of age.
Topics: Aging; Animals; Injections, Intraperitoneal; Liver; Male; Mathematics; Rats; Tryptophan; Tryptophan Oxygenase | 1969 |
Changes in tryptophan pyrrolase induction with age.
Topics: Aging; Animals; In Vitro Techniques; Kinetics; Liver; Oxygenases; Rats; Tryptophan; Tryptophan Oxygenase | 1965 |
[On the possibility that the greater duration of the insulin effect in aged animals is due to a blocking of insulinase].
Topics: Aging; Animals; Blood Glucose; Endopeptidases; Insulin; Rats; Tryptophan | 1965 |
Tryptophan accumulation and tryptophan pyrrolase induction in rat liver as a function of age.
Topics: Aging; Animals; Injections, Intraperitoneal; Kinetics; Liver; Male; Oxygenases; Rats; Tryptophan; Tryptophan Oxygenase | 1966 |
Induction of tryptophan pyrrolase activity in starving rabbits of different ages.
Topics: Aging; Animals; Animals, Newborn; Enzyme Induction; Female; Liver; Male; Oxygenases; Rabbits; Starvation; Tryptophan; Tryptophan Oxygenase | 1966 |