tryptophan and 2019 Novel Coronavirus Disease

tryptophan has been researched along with 2019 Novel Coronavirus Disease in 52 studies

Research

Studies (52)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's52 (100.00)2.80

Authors

AuthorsStudies
Borrego, JC; Castañeda-Delgado, JE; Enciso-Moreno, JA; Fernández-Ruiz, JC; Herrera-Van Oostdam, AS; López, JA; López-Hernández, Y; Mandal, R; Monárrez-Espino, J; Ochoa-González, F; Oropeza-Valdez, JJ; Soto-Guzmán, E; Trejo Medinilla, FM; Wishart, DS; Zhang, L; Zheng, J1
Akpan, IJ; Buehler, PW; Cendali, FI; D'Alessandro, A; Francis, RO; Gamboni, F; Hod, EA; Hudson, KE; Kahn, S; Katneni, U; Moriconi, C; Nemkov, T; Reisz, JA; Roh, D; Spitalnik, SL; Tanaka, K; Thangaraju, K; Thomas, T; Valk, JE; Wei, AZ; Zimring, JC1
Bollag, WB; Cantu, N; Fulzele, S; Hamrick, MW; Hill, WD; Isales, CM; Kolhe, R; Kumar, S; McGee-Lawrence, ME; Vyavahare, S1
Chen, W; Fang, J; Feng, C; Han, Y; Hou, P; Liu, Z; Melino, G; Shao, C; Shi, Y; Verkhratsky, A; Wang, Y; Xu, C; Zuo, M1
Jain, A1
Alvarenga, AC; Appel, RM; Arima, EC; Ayache, R; Budib, MA; D'Amora, P; Diaz, RS; Evans, SS; Júnior, SS; Martins, WG; Nagourney, RA; Palma, AM; Pontes, HBD; Salzgeber, MB; Silva, FC; Silva, IDCG; Silva, NLF; Silva, RMS1
Bugiani, M; Dijkhuis, A; Duitman, JW; Geeraerts, Z; Guo, L; Lutter, R; Nossent, EJ; Roos, E; Schurink, B; van der Valk, P; van Vught, L; Vaz, FM; Vlaar, AP; Yeh, SR1
Baranyi, A; Enko, D; Meinitzer, A; Michaelis, S; Schnedl, WJ; Zelzer, S1
Frye, M; Haddad, M; Huber, S; Kirchhof, P; Lohse, A; Maas, C; Masoodi, M; Nofer, JR; Peschka, M; Renné, T; Schmiedel, S1
Altunçekiç Yıldırım, A; Ceran Serdar, C; Cihan, M; Doğan, Ö; Kurt, C; Serdar, MA1
Guarnieri, T1
de Athaide, MM; de Mattos Barbosa, MG; de Oliveira, JADP; Jardim, MM; Moraes, MO; Pinheiro, RO; Rahman, AU1
Kim, B; Park, C; Park, T1
Gray, HB; Morales, M; Oyala, PH; Ravanfar, R; Winkler, JR1
Belkhir, L; Bommer, GT; De Greef, J; Dewulf, JP; Gatto, L; Jadoul, M; Laterre, PF; Marie, S; Martin, M; Morelle, J; Oguz, F; Wittebole, X; Yombi, JC1
Buyukkoruk, M; Candansayar, S; Deveci-Bulut, TS; Gulbahar, O; Kucukkarapinar, M; Senol, E; Yay-Pence, A; Yaz-Aydin, G; Yildiz, Y1
Al-Hakeim, HK; Algon, AAA; Almulla, AF; Maes, M; Supasitthumrong, T; Tunvirachaisakul, C1
Albóniga-Díez, OE; Barbas, C; Bartolome-Sánchez, S; Blanca-López, N; Blancas, R; Brochado-Kith, O; Ceballos, FC; Cuadros-González, J; Fernández-Rodríguez, A; Jiménez-Sousa, MÁ; Martin-Vicente, M; Martínez, I; Martinez-Acitores, IR; Martínez-González, O; Peréz-García, F; Resino, S; Ryan, P; Vidal-Alcántara, EJ; Virseda-Berdices, A1
Abrams, JA; Blackett, JW; Chang, L; Elkind, MSV; Freedberg, DE; Margolis, KG; O'Byrne, S; Purpura, L; Sun, Y; Wainberg, M; Wang, HH1
Arakawa, N; Hasegawa, C; Imai, K; Ishikawa, R; Kitamura, I; Maeda, T; Ogawa, K; Saito, K; Saito, Y; Sun, Y1
Abendroth, D; Bizjak, DA; Börner, N; Bösch, F; Buhl, JL; Drunin, G; Durner, J; Stangl, M1
Hall, CK; Herrera, SM; Hudalla, GA; Sarma, S; Xiao, X1
Al-Hroub, H; Alsayed, HAH; Halwani, R; Hamid, Q; Mahboub, B; Mohamed, HA; Osman, RS; Saheb Sharif-Askari, F; Saheb Sharif-Askari, N; Salameh, L; Semreen, MH; Soares, NC1
Baranyi, A; Enko, D; Herrmann, M; Meinitzer, A; Michaelis, S; Schnedl, WJ; Schneider, C; Zelzer, S2
Arévalo-Cortés, A; Damania, A; Granada, Y; Mejia, R; Triana-Chavez, O; Zuluaga, S1
Brodmann, M; Eller, K; Eller, P; Kirsch, AH; Magnes, C; Oberhuber, M; Pieber, T; Prietl, B; Prugger, EM; Rosenkranz, AR; Schmaldienst, S; Schuller, M; Zügner, E1
Boys, V; Bustamante, S; Chang, J; Leong, RW; Paramsothy, S; Pudipeddi, A; Wasinger, VC; Yau, Y1
Barberis, E; Bleve, A; Bombace, S; Bottazzi, B; Condorelli, G; Consonni, FM; Durante, B; Garlatti, V; Manfredi, M; Marengo, E; My, I; Pandolfo, C; Sica, A; Torri, V; Vanella, VV1
Gančarčíková, M; Javorská, L; Koblížek, V; Krčmová, LK; Matoušová, K; Melichar, B; Skála, M; Škop, J; Šmahel, P; Turoňová, D1
Allen-Davidian, Y; Bracken, SG; Brew, BJ; Byrne, A; Chow, S; Cysique, LA; Darley, DR; Dehhaghi, M; Dore, GJ; Guillemin, GJ; Heng, B; Jakabek, D; Kelleher, A; Matthews, GV; Phetsouphanh, C; Staats Pires, A1
Adhav, A; Bravo, J; Espinosa, C; Forcada-Nadal, A; Francés, C; Gargantilla, M; Geller, R; Gougeard, N; Hernández-Sierra, MDP; Llacer, JL; López-Redondo, ML; Marco-Marín, C; Marina, A; Martí-Marí, O; Martínez-Gualda, B; Melero, R; Pérez-Pérez, MJ; Rubio, V; Rubio-Del-Campo, A; Ruiz-Partida, R; San-Félix, A; Villamayor-Belinchón, L1
Bruckner, T; Deisenhammer, EA; Egeter, J; Galffy, M; Giesinger, JM; Gostner, JM; Holzner, B; Hüfner, K; Lehmann, J; Nelles, P; Oberhammer, M; Rockenschaub, J; Sacher, M; Sperner-Unterweger, B; Tymoszuk, P; Vedova, S1
Badawy, AA1
Appelman, B; Brinkman, P; Bugiani, M; Dekker, T; Dijkhuis, A; Duitman, JW; Guo, L; Houtkooper, RH; Lavell, HAA; Lutter, R; Mooij-Kalverda, K; Sikkens, JJ; Smids, BS; van Vugt, M; van Weeghel, M; Vaz, FM; Wüst, RCI1
Abed, AK; Al-Hakeim, HK; Almulla, AF; Maes, M; Rouf Moustafa, S1
Davison, AS; Goodacre, R; Kell, DB; Roberts, I; Taylor, JM; Winder, CL; Wright Muelas, M1
de Vries, BEK; de Vries, IEJ; Kooij, JJS; Nutma, I; Rus, CP1
Shader, RI1
Bertolone, L; D'Alessandro, A; Francis, RO; Hansen, KC; Hod, EA; Hudson, KE; Nemkov, T; Reisz, JA; Spitalnik, SL; Stefanoni, D; Thomas, T; Zimring, JC1
Robson, B1
Jo, S; Kim, DY; Kim, MS; Kim, S; Shin, DH1
Andres, CR; Benz-de Bretagne, I; Bernard, L; Bessy, C; Blasco, H; Boulard, P; Cannet, P; Emond, P; Guillon, A; Hérault, O; Lefevre, A; Lumbu, H; Marlet, J; Morel, T; Piver, E; Plantier, L; Stefic, K; Vourc'h, P1
Andersson, LM; Fuchs, D; Gisslen, M; Gostner, JM; Nilsson, S; Robertson, J1
Aceti, A; Bonfini, R; Borro, M; Capi, M; Casolla, B; Curto, M; De Bernardini, D; De Luca, O; Fazio, F; Gentile, G; Lionetto, L; Marchetti, P; Nicoletti, F; Petrucca, A; Pomes, LM; Ricci, A; Rocco, M; Salerno, G; Santino, I; Schillizzi, S; Simmaco, M; Torre, MS; Ulivieri, M1
Anderson, G; Carbone, A; Mazzoccoli, G1
Collier, ME; Giorgini, F; Scrutton, NS; Zhang, S1
Gomez-Gomez, A; Haro, N; Khymenets, O; Marín-Corral, J; Masclans, JR; Muñoz-Bermúdez, R; Pascual-Guardia, S; Pérez-Terán, P; Pozo, OJ; Restrepo, MI; Rodríguez-Morató, J; Salazar-Degracia, A1
Eroğlu, BÇ; Eroğlu, İ; Güven, GS1
Fu, J; Hu, B; Jiang, YH; Liu, CL; Qin, WH; Wang, HY1
Broadhurst, DI; Cai, Y; Casanovas-Massana, A; Israelow, B; Iwasaki, A; Johnson, CH; Khan, SA; Kim, DJ; Klein, J; Ko, AI; Lucas, C; Ma, S; Mao, T; Moore, AJ; Muenker, MC; Oh, JE; Rattray, NJW; Silva, J; Takahashi, T; Wong, P; Yan, H1
Cisneros, IE; Cunningham, KA1

Reviews

8 review(s) available for tryptophan and 2019 Novel Coronavirus Disease

ArticleYear
Tryptophan-Kynurenine Pathway in COVID-19-Dependent Musculoskeletal Pathology: A Minireview.
    Mediators of inflammation, 2021, Volume: 2021

    Topics: Animals; Bone Diseases; COVID-19; Humans; Kynurenine; Muscular Diseases; Receptors, Aryl Hydrocarbon; SARS-CoV-2; Signal Transduction; Tryptophan

2021
Redressing the interactions between stem cells and immune system in tissue regeneration.
    Biology direct, 2021, 10-20, Volume: 16, Issue:1

    Topics: Animals; Cell Adhesion Molecules; Cell Differentiation; Cell Proliferation; COVID-19; Humans; Immune System; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Insulin-Like Growth Factor II; Interferon-gamma; Kynurenic Acid; Kynurenine; Macrophages; Mice; Muscles; Oxidative Phosphorylation; Receptors, Aryl Hydrocarbon; Regeneration; Stem Cells; Tryptophan; Tumor Necrosis Factor-alpha

2021
Hypothesis: Emerging Roles for Aryl Hydrocarbon Receptor in Orchestrating CoV-2-Related Inflammation.
    Cells, 2022, 02-13, Volume: 11, Issue:4

    Topics: Adaptive Immunity; Amino Acid Transport Systems, Neutral; Angiotensin-Converting Enzyme 2; Basic Helix-Loop-Helix Transcription Factors; COVID-19; Humans; Immunity, Innate; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenine; Receptors, Aryl Hydrocarbon; SARS-CoV-2; Signal Transduction; Tryptophan

2022
Kynurenines in the Pathogenesis of Peripheral Neuropathy During Leprosy and COVID-19.
    Frontiers in cellular and infection microbiology, 2022, Volume: 12

    Topics: COVID-19; Humans; Kynurenine; Leprosy; Peripheral Nervous System Diseases; SARS-CoV-2; Tryptophan

2022
The tryptophan catabolite or kynurenine pathway in COVID-19 and critical COVID-19: a systematic review and meta-analysis.
    BMC infectious diseases, 2022, Jul-15, Volume: 22, Issue:1

    Topics: COVID-19; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Tryptophan

2022
Tryptophan Metabolites and Aryl Hydrocarbon Receptor in Severe Acute Respiratory Syndrome, Coronavirus-2 (SARS-CoV-2) Pathophysiology.
    International journal of molecular sciences, 2021, Feb-05, Volume: 22, Issue:4

    Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; COVID-19; Humans; Inflammation; Receptors, Aryl Hydrocarbon; Respiratory Distress Syndrome; SARS-CoV-2; Tryptophan

2021
Inflammation control and improvement of cognitive function in COVID-19 infections: is there a role for kynurenine 3-monooxygenase inhibition?
    Drug discovery today, 2021, Volume: 26, Issue:6

    Topics: Animals; Cognition; COVID-19; Humans; Inflammation; Kynurenine; Kynurenine 3-Monooxygenase; Neuroprotective Agents; Signal Transduction; Sulfonamides; Thiazoles; Tryptophan

2021
Covid-19 interface with drug misuse and substance use disorders.
    Neuropharmacology, 2021, 10-15, Volume: 198

    Topics: Adaptation, Psychological; Angiotensin-Converting Enzyme 2; Animals; Axons; Comorbidity; COVID-19; Disease Susceptibility; Drug Misuse; Endothelial Cells; Humans; Immunity, Innate; Inflammation; Kynurenine; Neurons; Neurotransmitter Agents; Olfactory Mucosa; Pandemics; SARS-CoV-2; Social Isolation; Stress, Psychological; Substance-Related Disorders; Tryptophan; Viral Tropism

2021

Trials

1 trial(s) available for tryptophan and 2019 Novel Coronavirus Disease

ArticleYear
Decreased Gut Microbiome Tryptophan Metabolism and Serotonergic Signaling in Patients With Persistent Mental Health and Gastrointestinal Symptoms After COVID-19.
    Clinical and translational gastroenterology, 2022, 10-01, Volume: 13, Issue:10

    Topics: COVID-19; Gastrointestinal Diseases; Gastrointestinal Microbiome; Humans; Mental Health; Serotonin; Tryptophan

2022

Other Studies

43 other study(ies) available for tryptophan and 2019 Novel Coronavirus Disease

ArticleYear
Immunometabolic signatures predict risk of progression to sepsis in COVID-19.
    PloS one, 2021, Volume: 16, Issue:8

    Topics: Adult; Area Under Curve; Chemokines; COVID-19; Cytokines; Female; Humans; Kynurenine; Lymphocytes; Male; Metabolomics; Middle Aged; Neutrophils; Retrospective Studies; Risk Factors; ROC Curve; SARS-CoV-2; Sepsis; Severity of Illness Index; Tryptophan

2021
Biological and Clinical Factors Contributing to the Metabolic Heterogeneity of Hospitalized Patients with and without COVID-19.
    Cells, 2021, 09-02, Volume: 10, Issue:9

    Topics: Acute Disease; Adult; Amino Acids; Body Mass Index; Carnitine; Cohort Studies; COVID-19; Fatty Acids; Female; Humans; Kynurenine; Machine Learning; Metabolomics; Middle Aged; Prognosis; Prospective Studies; SARS-CoV-2; Severity of Illness Index; Tryptophan

2021
Deregulated kynurenine metabolism - An alternate hypothesis for COVID-19 associated anosmia.
    Medical hypotheses, 2021, Volume: 157

    Topics: Anosmia; COVID-19; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; SARS-CoV-2; Tryptophan

2021
Towards risk stratification and prediction of disease severity and mortality in COVID-19: Next generation metabolomics for the measurement of host response to COVID-19 infection.
    PloS one, 2021, Volume: 16, Issue:12

    Topics: Adult; Aged; Area Under Curve; Carnitine; Citrulline; COVID-19; Female; Glutamic Acid; Humans; Kynurenine; Male; Metabolome; Metabolomics; Middle Aged; Ornithine; Risk Factors; ROC Curve; SARS-CoV-2; Severity of Illness Index; Tryptophan

2021
Indoleamine 2,3-dioxygenase (IDO)-1 and IDO-2 activity and severe course of COVID-19.
    The Journal of pathology, 2022, Volume: 256, Issue:3

    Topics: 3-Hydroxyanthranilic Acid; Adult; Aged; Apoptosis; Autopsy; Brain; COVID-19; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Lung; Middle Aged; Myocardium; Prospective Studies; Quinolinic Acid; Severity of Illness Index; Tryptophan

2022
Assessment of tryptophan and kynurenine as prognostic markers in patients with SARS-CoV-2.
    Clinica chimica acta; international journal of clinical chemistry, 2022, Jan-15, Volume: 525

    Topics: COVID-19; Humans; Kynurenine; Prognosis; SARS-CoV-2; Tryptophan

2022
Disturbed lipid and amino acid metabolisms in COVID-19 patients.
    Journal of molecular medicine (Berlin, Germany), 2022, Volume: 100, Issue:4

    Topics: Biomarkers; COVID-19; Humans; Lipids; Metabolomics; Pandemics; Tryptophan

2022
Kynurenine pathway in Coronavirus disease (COVID-19): Potential role in prognosis.
    Journal of clinical laboratory analysis, 2022, Volume: 36, Issue:3

    Topics: Adult; Aged; COVID-19; Female; Humans; Kynurenic Acid; Kynurenine; Male; Middle Aged; Picolinic Acids; Prognosis; Quinolinic Acid; SARS-CoV-2; Tryptophan

2022
DeepHisCoM: deep learning pathway analysis using hierarchical structural component models.
    Briefings in bioinformatics, 2022, 09-20, Volume: 23, Issue:5

    Topics: Biological Factors; Carcinoma, Hepatocellular; COVID-19; Deep Learning; Gonadotropin-Releasing Hormone; Humans; Isoleucine; Leucine; Liver Neoplasms; Lysine; Mitogen-Activated Protein Kinases; Phenylalanine; Tryptophan; Tyrosine; Valine

2022
Copper(II) Binding to the Intrinsically Disordered C-Terminal Peptide of SARS-CoV-2 Virulence Factor Nsp1.
    Inorganic chemistry, 2022, Jun-20, Volume: 61, Issue:24

    Topics: Circular Dichroism; Copper; COVID-19; Humans; Peptides; SARS-CoV-2; Tryptophan; Viral Nonstructural Proteins; Virulence Factors

2022
Urine metabolomics links dysregulation of the tryptophan-kynurenine pathway to inflammation and severity of COVID-19.
    Scientific reports, 2022, 06-15, Volume: 12, Issue:1

    Topics: Biomarkers; Chromatography, Liquid; COVID-19; Humans; Inflammation; Kynurenine; Metabolomics; SARS-CoV-2; Tandem Mass Spectrometry; Tryptophan

2022
Psychological outcomes of COVID-19 survivors at sixth months after diagnose: the role of kynurenine pathway metabolites in depression, anxiety, and stress.
    Journal of neural transmission (Vienna, Austria : 1996), 2022, Volume: 129, Issue:8

    Topics: Anxiety; Biomarkers; COVID-19; Depression; Humans; Kynurenic Acid; Kynurenine; Survivors; Tryptophan

2022
Metabolic Profiling at COVID-19 Onset Shows Disease Severity and Sex-Specific Dysregulation.
    Frontiers in immunology, 2022, Volume: 13

    Topics: COVID-19; Cross-Sectional Studies; Cytokines; Disease Progression; Female; Humans; Kynurenine; Male; Retrospective Studies; SARS-CoV-2; Severity of Illness Index; Tryptophan

2022
Characterization of serotonin as a candidate biomarker of severity and prognosis of COVID-19 using LC/MS analysis.
    Journal of pharmacological sciences, 2022, Volume: 150, Issue:2

    Topics: Biomarkers; Chromatography, Liquid; COVID-19; Humans; Kynurenine; Mass Spectrometry; Prognosis; Serotonin; Tryptophan

2022
Kynurenine serves as useful biomarker in acute, Long- and Post-COVID-19 diagnostics.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; C-Reactive Protein; COVID-19; COVID-19 Testing; Humans; Interleukin-6; Kynurenine; Middle Aged; Post-Acute COVID-19 Syndrome; SARS-CoV-2; Tryptophan; Young Adult

2022
Computational Design and Experimental Validation of ACE2-Derived Peptides as SARS-CoV-2 Receptor Binding Domain Inhibitors.
    The journal of physical chemistry. B, 2022, 10-20, Volume: 126, Issue:41

    Topics: Angiotensin-Converting Enzyme 2; COVID-19; Humans; Pandemics; Peptides; Protein Binding; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Tryptophan

2022
Saliva metabolomic profile of COVID-19 patients associates with disease severity.
    Metabolomics : Official journal of the Metabolomic Society, 2022, 10-22, Volume: 18, Issue:11

    Topics: Aminolevulinic Acid; Biomarkers; C-Reactive Protein; Chromatography, Liquid; COVID-19; Humans; Kynurenine; Linoleic Acid; Metabolomics; Saliva; SARS-CoV-2; Severity of Illness Index; Sphingosine; Tandem Mass Spectrometry; Tryptophan

2022
Alteration of the kynurenine pathway is inversely associated with the humoral immune response in patients with SARS-CoV-2.
    Clinica chimica acta; international journal of clinical chemistry, 2022, Dec-01, Volume: 537

    Topics: COVID-19; Humans; Immunity, Humoral; Kynurenine; SARS-CoV-2; Tryptophan

2022
Association of Midgut Bacteria and Their Metabolic Pathways with Zika Infection and Insecticide Resistance in Colombian
    Viruses, 2022, 10-06, Volume: 14, Issue:10

    Topics: Aedes; Alginates; Animals; Anti-Infective Agents; Arboviruses; ATP-Binding Cassette Transporters; Bacteria; Colombia; COVID-19; Dengue; Female; Humans; Insecticide Resistance; Insecticides; Metabolic Networks and Pathways; Mosquito Vectors; Mucins; Pandemics; Phenazines; Pyrethrins; Tryptophan; Zika Virus; Zika Virus Infection

2022
Alterations in the Kynurenine-Tryptophan Pathway and Lipid Dysregulation Are Preserved Features of COVID-19 in Hemodialysis.
    International journal of molecular sciences, 2022, Nov-15, Volume: 23, Issue:22

    Topics: COVID-19; Humans; Kynurenine; Lipids; Renal Dialysis; Tryptophan

2022
Tryptophan Metabolism 'Hub' Gene Expression Associates with Increased Inflammation and Severe Disease Outcomes in COVID-19 Infection and Inflammatory Bowel Disease.
    International journal of molecular sciences, 2022, Nov-26, Volume: 23, Issue:23

    Topics: COVID-19; Humans; Inflammation; Inflammatory Bowel Diseases; Proteomics; Transcriptome; Tryptophan

2022
Immunometabolic interference between cancer and COVID-19.
    Frontiers in immunology, 2023, Volume: 14

    Topics: COVID-19; Humans; Leukocytes, Mononuclear; NAD; Neoplasms; SARS-CoV-2; Tryptophan

2023
Neopterin and kynurenine in serum and urine as prognostic biomarkers in hospitalized patients with delta and omicron variant SARS-CoV-2 infection.
    Clinical chemistry and laboratory medicine, 2023, 10-26, Volume: 61, Issue:11

    Topics: Biomarkers; COVID-19; Humans; Kynurenine; Neopterin; Oxygen; Prognosis; SARS-CoV-2; Tryptophan

2023
The kynurenine pathway relates to post-acute COVID-19 objective cognitive impairment and PASC.
    Annals of clinical and translational neurology, 2023, Volume: 10, Issue:8

    Topics: Adult; Biomarkers; Cognitive Dysfunction; COVID-19; Female; Humans; Kynurenine; Male; Middle Aged; Post-Acute COVID-19 Syndrome; Tryptophan

2023
C-2 Thiophenyl Tryptophan Trimers Inhibit Cellular Entry of SARS-CoV-2 through Interaction with the Viral Spike (S) Protein.
    Journal of medicinal chemistry, 2023, 08-10, Volume: 66, Issue:15

    Topics: Angiotensin-Converting Enzyme 2; COVID-19; Cryoelectron Microscopy; Humans; Protein Binding; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Tryptophan

2023
The effect of inflammation, SARS-CoV-2 infection, age and mental health on serotonin, and kynurenine and catecholamine pathway metabolites.
    Psychoneuroendocrinology, 2023, Volume: 156

    Topics: COVID-19; Cross-Sectional Studies; Dopamine; Humans; Inflammation; Kynurenine; Mental Health; Phenylalanine; SARS-CoV-2; Serotonin; Tryptophan; Tyrosine

2023
The kynurenine pathway of tryptophan metabolism: a neglected therapeutic target of COVID-19 pathophysiology and immunotherapy.
    Bioscience reports, 2023, 08-31, Volume: 43, Issue:8

    Topics: COVID-19; Humans; Immunotherapy; Kynurenine; NAD; Poly(ADP-ribose) Polymerase Inhibitors; SARS-CoV-2; Tryptophan

2023
Prolonged indoleamine 2,3-dioxygenase-2 activity and associated cellular stress in post-acute sequelae of SARS-CoV-2 infection.
    EBioMedicine, 2023, Volume: 94

    Topics: Chromatography, Liquid; COVID-19; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Leukocytes, Mononuclear; Post-Acute COVID-19 Syndrome; SARS-CoV-2; Tandem Mass Spectrometry; Tryptophan

2023
Anxiety due to Long COVID is partially driven by activation of the tryptophan catabolite (TRYCAT) pathway.
    Asian journal of psychiatry, 2023, Volume: 88

    Topics: Anxiety; COVID-19; Humans; Kynurenine; Post-Acute COVID-19 Syndrome; Tryptophan

2023
The possible role of quinolinic acid as a predictive marker in patients with SARS-CoV-2.
    Clinica chimica acta; international journal of clinical chemistry, 2023, Oct-01, Volume: 550

    Topics: C-Reactive Protein; COVID-19; Humans; Kynurenine; Procalcitonin; Quinolinic Acid; SARS-CoV-2; Tryptophan

2023
Quantitative LC-MS study of compounds found predictive of COVID-19 severity and outcome.
    Metabolomics : Official journal of the Metabolomic Society, 2023, 10-18, Volume: 19, Issue:11

    Topics: Chromatography, Liquid; COVID-19; Humans; Kynurenic Acid; Metabolomics; SARS-CoV-2; Tandem Mass Spectrometry; Tryptophan

2023
Treatment of 95 post-Covid patients with SSRIs.
    Scientific reports, 2023, 11-02, Volume: 13, Issue:1

    Topics: COVID-19; Fatigue Syndrome, Chronic; Humans; Kynurenine; Primary Dysautonomias; Selective Serotonin Reuptake Inhibitors; Tryptophan

2023
COVID-19, interferons, and depression: A commentary.
    Psychiatry research, 2020, Volume: 291

    Topics: Betacoronavirus; Coronavirus Infections; COVID-19; Depression; Humans; Interferons; Pandemics; Pneumonia, Viral; SARS-CoV-2; Serotonin; Tryptophan

2020
COVID-19 infection alters kynurenine and fatty acid metabolism, correlating with IL-6 levels and renal status.
    JCI insight, 2020, 07-23, Volume: 5, Issue:14

    Topics: Adult; Aged; Amino Acids; Betacoronavirus; Blood Glucose; Case-Control Studies; Coronavirus Infections; COVID-19; Creatine; Creatinine; Cystine; Fatty Acids; Fatty Acids, Nonesterified; Female; Humans; Interleukin-6; Kynurenine; Male; Metabolome; Metabolomics; Methionine; Middle Aged; Oxidative Stress; Pandemics; Pneumonia, Viral; Polyamines; Proteolysis; Renal Insufficiency; SARS-CoV-2; Tryptophan

2020
Bioinformatics studies on a function of the SARS-CoV-2 spike glycoprotein as the binding of host sialic acid glycans.
    Computers in biology and medicine, 2020, Volume: 122

    Topics: Algorithms; Amino Acid Motifs; Betacoronavirus; Binding Sites; Computational Biology; Coronavirus Infections; COVID-19; Humans; Molecular Conformation; N-Acetylneuraminic Acid; Pandemics; Pneumonia, Viral; Polysaccharides; SARS-CoV-2; Severe acute respiratory syndrome-related coronavirus; Spike Glycoprotein, Coronavirus; Tryptophan

2020
Flavonoids with inhibitory activity against SARS-CoV-2 3CLpro.
    Journal of enzyme inhibition and medicinal chemistry, 2020, Volume: 35, Issue:1

    Topics: Antiviral Agents; Betacoronavirus; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Drug Design; Flavonoids; Fluorescence Resonance Energy Transfer; Humans; Molecular Docking Simulation; Pandemics; Pneumonia, Viral; Polyproteins; Protease Inhibitors; Protein Binding; Protein Conformation; SARS-CoV-2; Spectrophotometry; Tryptophan; Viral Proteins

2020
The specific metabolome profiling of patients infected by SARS-COV-2 supports the key role of tryptophan-nicotinamide pathway and cytosine metabolism.
    Scientific reports, 2020, 10-08, Volume: 10, Issue:1

    Topics: Aged; Aged, 80 and over; Betacoronavirus; Biomarkers; Coronavirus Infections; COVID-19; Cytosine; Early Diagnosis; Female; France; Humans; Male; Metabolome; Metabolomics; Middle Aged; Niacinamide; Pandemics; Pneumonia, Viral; Prognosis; Reproducibility of Results; SARS-CoV-2; Sensitivity and Specificity; Severity of Illness Index; Tryptophan

2020
Serum neopterin levels in relation to mild and severe COVID-19.
    BMC infectious diseases, 2020, Dec-10, Volume: 20, Issue:1

    Topics: Adult; Aged; Biomarkers; COVID-19; Critical Care; Female; Hospitalization; Humans; Kynurenine; Male; Middle Aged; Neopterin; Pandemics; Prognosis; SARS-CoV-2; Tryptophan

2020
Increased kynurenine-to-tryptophan ratio in the serum of patients infected with SARS-CoV2: An observational cohort study.
    Biochimica et biophysica acta. Molecular basis of disease, 2021, 03-01, Volume: 1867, Issue:3

    Topics: Aged; Biomarkers; COVID-19; Female; Humans; Kynurenine; Lymphocyte Count; Male; Middle Aged; SARS-CoV-2; Tryptophan

2021
Metabolic Signatures Associated with Severity in Hospitalized COVID-19 Patients.
    International journal of molecular sciences, 2021, Apr-30, Volume: 22, Issue:9

    Topics: Adult; Aged; Biomarkers; Ceramides; COVID-19; Female; Hospitalization; Humans; Kynurenine; Male; Metabolome; Metabolomics; Middle Aged; Prospective Studies; SARS-CoV-2; Severity of Illness Index; Tryptophan

2021
Altered tryptophan absorption and metabolism could underlie long-term symptoms in survivors of coronavirus disease 2019 (COVID-19).
    Nutrition (Burbank, Los Angeles County, Calif.), 2021, Volume: 90

    Topics: COVID-19; Humans; Post-Acute COVID-19 Syndrome; SARS-CoV-2; Survivors; Tryptophan

2021
Gut ACE2 Expression, Tryptophan Deficiency, and Inflammatory Responses The Potential Connection That Should Not Be Ignored During SARS-CoV-2 Infection.
    Cellular and molecular gastroenterology and hepatology, 2021, Volume: 12, Issue:4

    Topics: Angiotensin-Converting Enzyme 2; Animals; COVID-19; Cytokines; Epithelial Cells; Inflammation; Intestinal Mucosa; Intestines; Kynurenine; Lipopolysaccharides; Mice; Mice, Knockout; Phenotype; Recombinant Proteins; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Tryptophan

2021
Kynurenic acid may underlie sex-specific immune responses to COVID-19.
    Science signaling, 2021, 07-06, Volume: 14, Issue:690

    Topics: Adult; Aged; Case-Control Studies; COVID-19; Cytokine Release Syndrome; Cytokines; Female; Humans; Kynurenic Acid; Logistic Models; Male; Metabolic Networks and Pathways; Metabolomics; Middle Aged; Multivariate Analysis; SARS-CoV-2; Severity of Illness Index; Sex Factors; Signal Transduction; Tryptophan

2021