trypanothione has been researched along with Trypanosomiasis in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aguilar-Pereyra, F; Castillo-Acosta, VM; García-Caballero, D; González-Pacanowska, D; Ruiz-Pérez, LM; Vidal, AE; Yagüe-Capilla, M | 1 |
| Fairlamb, AH; König, J; Stevens, MF; Wells, G; Wyatt, PG; Wyllie, S | 1 |
| Bellanda, M; Comini, MA; Krauth-Siegel, RL | 1 |
| Austin, SE; Douglas, KT; Khan, MO | 1 |
| Amssoms, K; Augustyns, K; Haemers, A; Rajan, PK; Yamani, A | 1 |
3 review(s) available for trypanothione and Trypanosomiasis
| Article | Year |
|---|---|
Mono- and dithiol glutaredoxins in the trypanothione-based redox metabolism of pathogenic trypanosomes.
Topics: Amino Acid Sequence; Animals; Conserved Sequence; Glutaredoxins; Glutathione; Humans; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Protein Conformation; Protozoan Proteins; Spermidine; Trypanosoma; Trypanosomiasis | 2013 |
Rational drug design using trypanothione reductase as a target for anti-trypanosomal and anti-leishmanial drug leads.
Topics: Adrenergic Uptake Inhibitors; Antiparasitic Agents; Drug Design; Enzyme Inhibitors; Glutathione; Imipramine; Leishmaniasis; Models, Biological; Molecular Structure; Oxidoreductases; Phenothiazines; Protozoan Infections; Sequence Homology, Amino Acid; Species Specificity; Spermidine; Trypanosomiasis | 1999 |
Trypanothione as a target in the design of antitrypanosomal and antileishmanial agents.
Topics: Animals; Drug Design; Glutathione; Humans; Molecular Structure; Spermidine; Trypanocidal Agents; Trypanosoma cruzi; Trypanosomiasis | 2001 |
2 other study(ies) available for trypanothione and Trypanosomiasis
| Article | Year |
|---|---|
Base excision repair plays an important role in the protection against nitric oxide- and in vivo-induced DNA damage in Trypanosoma brucei.
Topics: Animals; DNA Damage; DNA Repair; DNA, Protozoan; Female; Gene Expression; Genotype; Glutathione; Host-Parasite Interactions; Macrophages; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitrosative Stress; Parasitemia; Peroxidases; Phenotype; Protozoan Proteins; Spermidine; Thioredoxins; Trypanosoma brucei brucei; Trypanosomiasis; Uracil-DNA Glycosidase | 2019 |
Antitumor quinol PMX464 is a cytocidal anti-trypanosomal inhibitor targeting trypanothione metabolism.
Topics: Amide Synthases; Animals; Antineoplastic Agents; Benzothiazoles; Cysteine; Dose-Response Relationship, Drug; Glutathione; Hydroquinones; Protozoan Proteins; Spermidine; Thioredoxins; Time Factors; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis | 2011 |