Compounds > trypanothione

Page last updated: 2024-09-03

trypanothione and Leishmaniasis

trypanothione has been researched along with Leishmaniasis in 11 studies

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (9.09)	18.2507
2000's	3 (27.27)	29.6817
2010's	3 (27.27)	24.3611
2020's	4 (36.36)	2.80

Authors

Authors	Studies
Costi, R; Di Santo, R; Saccoliti, F	1
Arias, D; Guerrero, S; Parodi-Talice, A; Piñeyro, MD; Robello, C	1
Abbehausen, C; Aires, RL; Fontes, JV; Miguel, DC; Oliveira, LS; Rosa, LB	1
Battista, T; Bibi, A; Colotti, G; Costi, R; Di Muccio, T; Di Santo, R; Dubey, VK; Fiorillo, A; Gramiccia, M; Ilari, A; Madia, VN; Messore, A; Mocci, S; Prakash, J; Saccoliti, F; Vistoli, G; Yadav, S	1
Ali, V; Garg, G; Singh, K	1
Colotti, G; Fiorillo, A; Genovese, I; Ilari, A	1
Goyeneche-Patino, DA; Saravia, NG; Valderrama, L; Walker, J	1
Colotti, G; Ilari, A	1
Heby, O; Persson, L; Rentala, M	1
Austin, SE; Douglas, KT; Khan, MO	1
D'Silva, C; Daunes, S	1

Reviews

9 review(s) available for trypanothione and Leishmaniasis

Article	Year
Recent Advancement in the Search of Innovative Antiprotozoal Agents Targeting Trypanothione Metabolism. ChemMedChem, 2020, 12-15, Volume: 15, Issue:24 Topics: Amide Synthases; Amidohydrolases; Animals; Chagas Disease; Enzyme Inhibitors; Glutathione; Humans; Leishmania; Leishmaniasis; NADH, NADPH Oxidoreductases; Protozoan Proteins; Spermidine; Trypanocidal Agents; Trypanosoma	2020
Trypanothione Metabolism as Drug Target for Trypanosomatids. Current pharmaceutical design, 2021, Volume: 27, Issue:15 Topics: Animals; Glutathione; Humans; Leishmaniasis; Pharmaceutical Preparations; Spermidine	2021
A "Golden Age" for the discovery of new antileishmanial agents: Current status of leishmanicidal gold complexes and prospective targets beyond the trypanothione system. ChemMedChem, 2021, 06-07, Volume: 16, Issue:11 Topics: Animals; Antiprotozoal Agents; Drug Discovery; Glutathione; Humans; Leishmania; Leishmaniasis; Organogold Compounds; Oxidation-Reduction; Parasitic Sensitivity Tests; Spermidine	2021
Current Therapeutics, Their Problems and Thiol Metabolism as Potential Drug Targets in Leishmaniasis. Current drug metabolism, 2016, Volume: 17, Issue:9 Topics: Animals; Antiprotozoal Agents; Glutathione; Humans; Leishmania; Leishmaniasis; Spermidine; Sulfhydryl Compounds	2016
Polyamine-trypanothione pathway: an update. Future medicinal chemistry, 2017, Volume: 9, Issue:1 Topics: Antiprotozoal Agents; Biosynthetic Pathways; Enzyme Inhibitors; Glutathione; Humans; Leishmaniasis; Molecular Structure; Polyamines; Spermidine; Structure-Activity Relationship	2017
Polyamine metabolism in Leishmania: from arginine to trypanothione. Amino acids, 2011, Volume: 40, Issue:2 Topics: Arginine; Glutathione; Humans; Leishmania; Leishmaniasis; Polyamines; Protozoan Proteins; Spermidine	2011
Targeting the polyamine biosynthetic enzymes: a promising approach to therapy of African sleeping sickness, Chagas' disease, and leishmaniasis. Amino acids, 2007, Volume: 33, Issue:2 Topics: Adenosine; Adenosylmethionine Decarboxylase; Animals; Biogenic Polyamines; Chagas Disease; Eflornithine; Enzyme Inhibitors; Glutathione; Humans; Leishmania; Leishmaniasis; Ornithine Decarboxylase Inhibitors; Robenidine; Spermidine; Spermidine Synthase; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosoma cruzi; Trypanosomiasis, African	2007
Rational drug design using trypanothione reductase as a target for anti-trypanosomal and anti-leishmanial drug leads. Drug design and discovery, 1999, Volume: 16, Issue:1 Topics: Adrenergic Uptake Inhibitors; Antiparasitic Agents; Drug Design; Enzyme Inhibitors; Glutathione; Imipramine; Leishmaniasis; Models, Biological; Molecular Structure; Oxidoreductases; Phenothiazines; Protozoan Infections; Sequence Homology, Amino Acid; Species Specificity; Spermidine; Trypanosomiasis	1999
The therapeutic potential of inhibitors of the trypanothione cycle. Expert opinion on investigational drugs, 2002, Volume: 11, Issue:2 Topics: Animals; Chagas Disease; Enzyme Inhibitors; Glutathione; Humans; Leishmaniasis; NADH, NADPH Oxidoreductases; Receptors, Peptide; Spermidine; Structure-Activity Relationship; Thioredoxins; Trypanocidal Agents; Trypanosomiasis, African	2002

Other Studies

2 other study(ies) available for trypanothione and Leishmaniasis

Article	Year
Structure-guided approach to identify a novel class of anti-leishmaniasis diaryl sulfide compounds targeting the trypanothione metabolism. Amino acids, 2020, Volume: 52, Issue:2 Topics: Amino Acid Motifs; Antiprotozoal Agents; Catalytic Domain; Glutathione; Humans; Leishmania infantum; Leishmaniasis; Models, Molecular; NADH, NADPH Oxidoreductases; Protozoan Proteins; Spermidine; Sulfides	2020
Antimony resistance and trypanothione in experimentally selected and clinical strains of Leishmania panamensis. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:12 Topics: Animals; Antimony; Antiprotozoal Agents; Buthionine Sulfoximine; Drug Resistance; Glutathione; Humans; Leishmania; Leishmaniasis; Parasitic Sensitivity Tests; Spermidine	2008