Page last updated: 2024-09-03

troxacitabine and Cancer of Pancreas

troxacitabine has been researched along with Cancer of Pancreas in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Batist, G; Eatock, M; Hawkins, RE; Jolivet, J; Lapointe, R; Létourneau, R; Moore, M; Steward, W; Vincent, M; Whittom, R1
Bussom, S; Cheng, YC; Lam, W; Leung, CH1
Bouffard, DY; Cass, CE; Clarke, ML; Damaraju, VL; Gourdeau, H; Grey, M; Leblond, L; Mackey, JR; Wong, CK1
Adema, AD; Alexander, LE; Chu, CK; Daft, J; Hoebe, EK; Narayanasamy, J; Peters, GJ; Radi, M1
Jolivet, J; Locas, C; Marty, J; Von Hoff, DD; Weitman, S1
Günzburg, WH; Salmons, B1

Reviews

1 review(s) available for troxacitabine and Cancer of Pancreas

ArticleYear
Novel clinical strategies for the treatment of pancreatic carcinoma.
    Trends in molecular medicine, 2001, Volume: 7, Issue:1

    Topics: Adjuvants, Immunologic; Antibodies, Monoclonal; Antineoplastic Agents; Bile; Biotransformation; Cancer Vaccines; Carcinoma; Clinical Trials as Topic; Cytochrome P-450 CYP2B1; Cytosine; Deoxycytidine; Dioxolanes; DNA, Antisense; Endopeptidases; Enzyme Inhibitors; Gemcitabine; Genes, p53; Genes, ras; Genetic Therapy; Heat-Shock Proteins; Humans; Ifosfamide; Multicenter Studies as Topic; Neoplasm Proteins; Neoplastic Stem Cells; Pancreatic Neoplasms; Pectins; Pilot Projects; Polyamines; Prospective Studies; Prostheses and Implants; Sesquiterpenes; Spiro Compounds; Tissue Extracts; Topoisomerase I Inhibitors

2001

Trials

1 trial(s) available for troxacitabine and Cancer of Pancreas

ArticleYear
Phase II study of troxacitabine in chemotherapy-naive patients with advanced cancer of the pancreas: gastrointestinal tumors.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2005, Volume: 16, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Body Weight; Cytosine; Dioxolanes; Disease Progression; Female; Health Status; Humans; Infusions, Intravenous; Male; Middle Aged; Pain; Pancreatic Neoplasms; Survival Analysis; Treatment Outcome

2005

Other Studies

4 other study(ies) available for troxacitabine and Cancer of Pancreas

ArticleYear
The impact of hypoxic treatment on the expression of phosphoglycerate kinase and the cytotoxicity of troxacitabine and gemcitabine.
    Molecular pharmacology, 2007, Volume: 72, Issue:3

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma; Carcinoma, Hepatocellular; Cell Hypoxia; Cell Line, Tumor; Colonic Neoplasms; Cytosine; Deoxycytidine; Dioxolanes; DNA-(Apurinic or Apyrimidinic Site) Lyase; Gemcitabine; Humans; Liver Neoplasms; Pancreatic Neoplasms; Phosphoglycerate Kinase; Rhabdomyosarcoma

2007
Synergistic activity of troxacitabine (Troxatyl) and gemcitabine in pancreatic cancer.
    BMC cancer, 2007, Jul-03, Volume: 7

    Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Cytosine; Deoxycytidine; Dioxolanes; Drug Synergism; Female; Gemcitabine; Humans; Mice; Mice, Nude; Mice, SCID; Pancreatic Neoplasms; Treatment Outcome; Tritium; Tumor Cells, Cultured; Uridine; Xenograft Model Antitumor Assays

2007
Troxacitabine prodrugs for pancreatic cancer.
    Nucleosides, nucleotides & nucleic acids, 2007, Volume: 26, Issue:8-9

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cytosine; Dioxolanes; Drug Design; Drug Screening Assays, Antitumor; Humans; Pancreatic Neoplasms; Prodrugs

2007
The new dioxolane, (-)-2'-deoxy-3'-oxacytidine (BCH-4556, troxacitabine), has activity against pancreatic human tumor xenografts.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:4

    Topics: Animals; Antineoplastic Agents; Body Weight; Cytosine; Deoxycytidine; Dioxolanes; Dose-Response Relationship, Drug; Female; Gemcitabine; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Pancreatic Neoplasms; Transplantation, Heterologous; Tumor Cells, Cultured

2000