trovafloxacin has been researched along with Inflammation in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 6 (60.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kang, MG; Park, D; Park, T; Yang, H | 1 |
| Calderon, F; Contreras, JE; Garg, C; Loh, JM; Ramachandran, J; Seo, JH | 1 |
| Bleumink, R; Bol-Schoenmakers, M; Giustarini, G; Koenderman, L; Kruijssen, L; Pieters, R; Smit, J; van Roest, M; van Staveren, S; Vrisekoop, N; Wagenaar, L; Weaver, RJ | 1 |
| Blomme, EA; Ditewig, AC; Ganey, PE; Liguori, MJ; Roth, RA; Shaw, PJ; Waring, JF | 1 |
| Beggs, KM; Dugan, CM; Ganey, PE; Roth, RA; Shaw, PJ; Sparkenbaugh, EM | 1 |
| Ganey, PE; Roth, RA; Shaw, PJ | 1 |
| Bhaskaran, VM; Blomme, EA; Ditewig, AC; Ganey, PE; Lehman-McKeeman, LD; Liguori, MJ; Luyendyk, JP; Maddox, JF; Nelson, DM; Roth, RA; Waring, JF | 1 |
| Muller, CD; Peluso, J; Saab, L; Ubeaud-Sequier, G | 1 |
| Ganey, PE; Hopfensperger, MJ; Roth, RA; Shaw, PJ | 1 |
| Toyoda, T; Wanibuchi, H; Wei, M; Yamada, T; Yamano, S | 1 |
1 review(s) available for trovafloxacin and Inflammation
| Article | Year |
|---|---|
Idiosyncratic drug-induced liver injury and the role of inflammatory stress with an emphasis on an animal model of trovafloxacin hepatotoxicity.
Topics: Animals; Anti-Infective Agents; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drug-Related Side Effects and Adverse Reactions; Fluoroquinolones; Humans; Inflammation; Naphthyridines; Stress, Physiological | 2010 |
9 other study(ies) available for trovafloxacin and Inflammation
| Article | Year |
|---|---|
Trovafloxacin drives inflammation-associated drug-induced adverse hepatic reaction by changing macrophage polarization.
Topics: Chemical and Drug Induced Liver Injury; Drug-Related Side Effects and Adverse Reactions; Fluoroquinolones; Humans; Inflammation; Liver; Macrophages; Naphthyridines | 2022 |
Trovafloxacin attenuates neuroinflammation and improves outcome after traumatic brain injury in mice.
Topics: Animals; Anti-Infective Agents; Brain Injuries, Traumatic; Cell Line; Fluoroquinolones; Inflammation; Inflammation Mediators; Male; Mice; Mice, Inbred C57BL; Naphthyridines; Recovery of Function; Treatment Outcome | 2018 |
Trovafloxacin-Induced Liver Injury: Lack in Regulation of Inflammation by Inhibition of Nucleotide Release and Neutrophil Movement.
Topics: Animals; Anti-Infective Agents; Chemical and Drug Induced Liver Injury; Connexins; Fluoroquinolones; Hep G2 Cells; Humans; Inflammation; Intercellular Adhesion Molecule-1; Male; Mice, Inbred C57BL; Naphthyridines; Nerve Tissue Proteins; Neutrophil Infiltration; Neutrophils; Nucleotides; Tumor Necrosis Factor-alpha | 2019 |
Coexposure of mice to trovafloxacin and lipopolysaccharide, a model of idiosyncratic hepatotoxicity, results in a unique gene expression profile and interferon gamma-dependent liver injury.
Topics: Analysis of Variance; Animals; Chemical and Drug Induced Liver Injury; Female; Fluoroquinolones; Gene Expression; Hepatocytes; Inflammation; Interferon-gamma; Interleukin-18; Janus Kinases; Levofloxacin; Lipopolysaccharides; Liver; Liver Diseases; Male; Mice; Mice, Inbred BALB C; Naphthyridines; Necrosis; Ofloxacin; Oligonucleotide Array Sequence Analysis; STAT Transcription Factors; Transcriptional Activation | 2009 |
Trovafloxacin enhances TNF-induced inflammatory stress and cell death signaling and reduces TNF clearance in a murine model of idiosyncratic hepatotoxicity.
Topics: Animals; Anti-Infective Agents; Cell Death; Fluoroquinolones; Humans; Immunohistochemistry; Inflammation; Kidney; Liver; Male; Mice; Mice, Inbred C57BL; Models, Animal; Naphthyridines; Rats; Signal Transduction; Tumor Necrosis Factor-alpha | 2009 |
Comparison of TNFα to lipopolysaccharide as an inflammagen to characterize the idiosyncratic hepatotoxicity potential of drugs: Trovafloxacin as an example.
Topics: Animals; Anti-Infective Agents; Drug Interactions; Fluoroquinolones; Inflammation; Lipopolysaccharides; Liver; Naphthyridines; Rats; Rats, Sprague-Dawley; Transcriptome; Tumor Necrosis Factor-alpha | 2010 |
Implication of hepatic transporters (MDR1 and MRP2) in inflammation-associated idiosyncratic drug-induced hepatotoxicity investigated by microvolume cytometry.
Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Sub-Family B Member 4; Biological Transport; Chemical and Drug Induced Liver Injury; Flow Cytometry; Fluoroquinolones; Gene Expression Regulation; Hep G2 Cells; Hepatocytes; Humans; Inflammation; Ketolides; Lipopolysaccharides; Liver; Naphthyridines; Piperazines; Sulfonamides; Triazoles; Tumor Necrosis Factor-alpha; Xenobiotics | 2013 |
Lipopolysaccharide and trovafloxacin coexposure in mice causes idiosyncrasy-like liver injury dependent on tumor necrosis factor-alpha.
Topics: Alanine Transaminase; Animals; Anti-Infective Agents; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Etanercept; Fluoroquinolones; Immunoglobulin G; Inflammation; Levofloxacin; Lipopolysaccharides; Liver; Male; Mice; Mice, Inbred C57BL; Naphthyridines; Ofloxacin; Pentoxifylline; Receptors, Tumor Necrosis Factor; Time Factors; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2007 |
Inhibitory effect of Raphanobrassica on Helicobacter pylori-induced gastritis in Mongolian gerbils.
Topics: Animals; Brassicaceae; Chronic Disease; Disease Models, Animal; Gastritis; Gerbillinae; Glucosinolates; Helicobacter Infections; Helicobacter pylori; Imidoesters; Inflammation; Interleukin-6; Male; Oximes; Plant Extracts; RNA, Messenger; Sulfoxides | 2014 |