tropisetron has been researched along with Amnesia* in 1 studies
1 other study(ies) available for tropisetron and Amnesia
| Article | Year |
|---|---|
Enhancement of memory retrieval and attenuation of scopolamine-induced amnesia following administration of 5-HT3 antagonist ICS 205-930.
Experimental evidence suggests an important role of serotonin in the process of learning and memory. The present study investigated the effect of 5HT3-receptor antagonist (ICS 205-930) on retrieval of a previously learned aversive habit in the mouse. The effect of ICS 205-930 on scopolamine (3 mg/kg) induced amnesia was also studied. ICS 205-930 (1, 10 & 100 micrograms/kg) produced a dose-dependent increase in latency to cross into the dark chamber. The scopolamine induced memory impairment was significantly attenuated by ICS 205-930 (10 micrograms/kg). These results suggest that memory deficits may be susceptible to attenuation with non-cholinergic treatments. Topics: Amnesia; Animals; Indoles; Learning; Male; Memory; Memory Disorders; Mice; Scopolamine; Serotonin Antagonists; Tropisetron | 1991 |