Page last updated: 2024-11-05

tropicamide and Retrolental Fibroplasia

tropicamide has been researched along with Retrolental Fibroplasia in 18 studies

Tropicamide: One of the MUSCARINIC ANTAGONISTS with pharmacologic action similar to ATROPINE and used mainly as an ophthalmic parasympatholytic or mydriatic.

Research Excerpts

ExcerptRelevanceReference
"To observe and compare the effects of pupil dilation between Mydrin-P and compound tropicamide in the screening of retinopathy of prematurity."7.80Comparison of the mydriatic effects of mydrin-P and compound tropicamide in the screening of retinopathy of prematurity. ( Lu, Y; Luo, S; Wan, Z; Ye, Z; Yin, X, 2014)
"A comprehensive literature search was performed in PubMed, Cochrane library, Trip database, and Scopus, using the key words: "mydriasis", "techniques", "mydriatics", "dilating drops", "retinopathy of prematurity", "ROP", "phenylephrine", "cyclopentolate", "tropicamide", "smaller mydriatic drops", "reduction in drop size" to February 2019."5.05Alternative mydriasis techniques for retinopathy of prematurity screening. ( Kokkali, S; Lithoxopoulou, M; Mataftsi, A; Prousali, E; Seliniotaki, AK; Soubasi, V; Ziakas, N, 2020)
"5% tropicamide and 5% phenylephrine eyedrops in order to achieve a proper dilation in premature infants undergoing screening for retinopathy of prematurity."3.85Combination of 5% phenylephrine and 0.5% tropicamide eyedrops for pupil dilation in neonates is twice as effective as 0.5% tropicamide eyedrops alone. ( Barjol, A; Degoumois, A; Denion, E; Lux, AL; Mouriaux, F, 2017)
" Two cases of necrotizing enterocolitis could be ascribed to the use of tropicamide with a doubtful and plausible intrinsic imputability according to French imputability criteria."3.81[Serious adverse side effects after pupillary dilation in preterm infants]. ( Denion, E; Fedrizzi, S; Guillois, B; Lux, AL; Mouriaux, F; Peyro-Saint-Paul, L, 2015)
" After pupil dilation with 1 % tropicamide and 10 % phenylephrine for retinal examination, acute elevation of intraocular pressure (IOP) was observed in the right eye."3.81Acute angle-closure glaucoma in retinopathy of prematurity following pupil dilation. ( Chang, SH; Lee, YS; Wu, SC; Wu, WC, 2015)
"To observe and compare the effects of pupil dilation between Mydrin-P and compound tropicamide in the screening of retinopathy of prematurity."3.80Comparison of the mydriatic effects of mydrin-P and compound tropicamide in the screening of retinopathy of prematurity. ( Lu, Y; Luo, S; Wan, Z; Ye, Z; Yin, X, 2014)
" Here, two cases are presented in which we observed skin pallor around the eyes after instillation of phenylephrine 2."3.76The local vasoconstriction of infant's skin following instillation of mydriatic eye drops. ( Alpay, A; Battal, F; Ermis, B; Sagdik, HM; Ugurbas, SC, 2010)
" Otherwise, adverse events did not differ after either administration technique."3.11Efficacy and safety of mydriatic microdrops for retinopathy of prematurity screening: an external pilot crossover randomized controlled trial. ( Diamanti, E; Georgiou, E; Haidich, AB; Lithoxopoulou, M; Mataftsi, A; Seliniotaki, AK; Talimtzi, P; Ziakas, N, 2022)
"To evaluate systemic adverse events after screening for retinopathy of prematurity (ROP) performed with mydriatic."1.62Systemic adverse events after screening of retinopathy of prematurity with mydriatic. ( Imamura, T; Kakinoki, M; Maruo, Y; Obata, S; Ohji, M; Yanagi, T, 2021)
"5% drop is effective and safe as mydriatic combination for retinopathy of prematurity screening."1.51Efficiency and safety of phenylephrine and tropicamide used in premature retinopathy: a prospective observational study. ( Alpay, A; Aydemir, C; Canturk Ugurbas, S, 2019)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.56)18.7374
1990's1 (5.56)18.2507
2000's1 (5.56)29.6817
2010's10 (55.56)24.3611
2020's5 (27.78)2.80

Authors

AuthorsStudies
Obata, S1
Imamura, T1
Kakinoki, M1
Yanagi, T1
Maruo, Y1
Ohji, M1
Seliniotaki, AK2
Lithoxopoulou, M2
Talimtzi, P1
Georgiou, E1
Diamanti, E1
Ziakas, N2
Haidich, AB1
Mataftsi, A2
Alpay, A2
Canturk Ugurbas, S1
Aydemir, C1
Mimori, K1
Haneda, K1
Shimizu, H1
Yamashita, M1
Tanaka, H1
Prousali, E1
Kokkali, S1
Soubasi, V1
Bembich, S1
Demarini, S1
Cont, G1
Di Giusto, A1
Mazzolai, M1
Barbi, E1
Risso, FM1
Degirmencioglu, H1
Oncel, MY1
Calisici, E1
Say, B1
Uras, N1
Dilmen, U1
Lux, AL2
Mouriaux, F2
Guillois, B1
Fedrizzi, S1
Peyro-Saint-Paul, L1
Denion, E2
Luo, S1
Wan, Z1
Yin, X1
Ye, Z1
Lu, Y1
Wu, SC1
Lee, YS1
Wu, WC1
Chang, SH1
Agrawal, Y1
Patri, S1
Kalavakunta, JK1
Gupta, V1
Degoumois, A1
Barjol, A1
Ermis, B1
Ugurbas, SC1
Battal, F1
Sagdik, HM1
Phamonvaechavan, P1
Chutasmit, K1
Damrongrak, P1
Koukiatkul, S1
Wongkiatkajorn, T1
Ngerncham, S1
Cohen, AM1
Cook, N1
Harris, MC1
Ying, GS1
Binenbaum, G1
Rush, R1
Rush, S1
Nicolau, J1
Chapman, K1
Naqvi, M1
Isenberg, S1
Everett, S1
Parelhoff, E1
Berman, DH1
Deutsch, JA1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy and Safety of Mydriatic Microdrops Compared With Standard Drops for Retinopathy of Prematurity (ROP) Screening: a Pilot Randomized Clinical Trial[NCT04623684]Phase 425 participants (Actual)Interventional2020-03-24Completed
Efficiency and Safety of Phenylephrine and Tropicamide Used in Premature Retinopathy[NCT03448640]60 participants (Actual)Observational2016-01-15Completed
Efficacy and Safety of Mydriatic Microdrops for Retinopathy Of Prematurity Screening: a Non-inferiority Crossover Randomized Controlled Trial (MyMiROPS Trial)[NCT05043077]Phase 483 participants (Actual)Interventional2021-09-07Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for tropicamide and Retrolental Fibroplasia

ArticleYear
Alternative mydriasis techniques for retinopathy of prematurity screening.
    International ophthalmology, 2020, Volume: 40, Issue:12

    Topics: Humans; Infant; Infant, Newborn; Infant, Premature; Mydriasis; Mydriatics; Ophthalmic Solutions; Phe

2020
Alternative mydriasis techniques for retinopathy of prematurity screening.
    International ophthalmology, 2020, Volume: 40, Issue:12

    Topics: Humans; Infant; Infant, Newborn; Infant, Premature; Mydriasis; Mydriatics; Ophthalmic Solutions; Phe

2020
Alternative mydriasis techniques for retinopathy of prematurity screening.
    International ophthalmology, 2020, Volume: 40, Issue:12

    Topics: Humans; Infant; Infant, Newborn; Infant, Premature; Mydriasis; Mydriatics; Ophthalmic Solutions; Phe

2020
Alternative mydriasis techniques for retinopathy of prematurity screening.
    International ophthalmology, 2020, Volume: 40, Issue:12

    Topics: Humans; Infant; Infant, Newborn; Infant, Premature; Mydriasis; Mydriatics; Ophthalmic Solutions; Phe

2020

Trials

2 trials available for tropicamide and Retrolental Fibroplasia

ArticleYear
Efficacy and safety of mydriatic microdrops for retinopathy of prematurity screening: an external pilot crossover randomized controlled trial.
    Journal of perinatology : official journal of the California Perinatal Association, 2022, Volume: 42, Issue:3

    Topics: Heart Rate; Humans; Infant; Infant, Newborn; Infant, Premature; Mydriatics; Ophthalmic Solutions; Ph

2022
Comparison of the effectiveness of mydriasis by two instillation methods of combined 0.75% tropicamide and 2.5% phenylephrine eye drop in preterm infants.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2012, Volume: 95 Suppl 4

    Topics: Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Infant, Newborn; Infant, Premature; I

2012

Other Studies

15 other studies available for tropicamide and Retrolental Fibroplasia

ArticleYear
Systemic adverse events after screening of retinopathy of prematurity with mydriatic.
    PloS one, 2021, Volume: 16, Issue:9

    Topics: Body Weight; Drug-Related Side Effects and Adverse Reactions; Female; Gestational Age; Humans; Infan

2021
Efficiency and safety of phenylephrine and tropicamide used in premature retinopathy: a prospective observational study.
    BMC pediatrics, 2019, 11-06, Volume: 19, Issue:1

    Topics: Blood Pressure; Drug Therapy, Combination; Gestational Age; Humans; Infant, Newborn; Infant, Prematu

2019
Necrotizing enterocolitis after an eye examination with mydriatics.
    Pediatrics international : official journal of the Japan Pediatric Society, 2020, Volume: 62, Issue:2

    Topics: Constriction, Pathologic; Drug Combinations; Enterocolitis, Necrotizing; Humans; Infant, Extremely L

2020
Effect of mydriatic administration on cerebral haemodynamics and oxygenation in preterm infants.
    Acta ophthalmologica, 2020, Volume: 98, Issue:2

    Topics: Administration, Ophthalmic; Brain; Cerebrovascular Circulation; Drug Combinations; Female; Gestation

2020
Transient ileus associated with the use of mydriatics after screening for retinopathy of prematurity in a very low birth weight infant.
    Journal of pediatric ophthalmology and strabismus, 2014, Jul-08, Volume: 51 Online

    Topics: Adult; Drug Combinations; Female; Gestational Age; Humans; Ileus; Infant, Newborn; Infant, Very Low

2014
[Serious adverse side effects after pupillary dilation in preterm infants].
    Journal francais d'ophtalmologie, 2015, Volume: 38, Issue:3

    Topics: Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Enterocol

2015
Comparison of the mydriatic effects of mydrin-P and compound tropicamide in the screening of retinopathy of prematurity.
    Eye science, 2014, Volume: 29, Issue:4

    Topics: Humans; Infant, Newborn; Infant, Premature; Mydriasis; Mydriatics; Ophthalmic Solutions; Pupil; Reti

2014
Acute angle-closure glaucoma in retinopathy of prematurity following pupil dilation.
    BMC ophthalmology, 2015, Aug-08, Volume: 15

    Topics: Acute Disease; Child, Preschool; Drug Combinations; Female; Glaucoma, Angle-Closure; Humans; Intraoc

2015
Retinopathy of prematurity screening leading to cardiopulmonary arrest: fatal complication of a benign procedure.
    BMJ case reports, 2016, Jul-28, Volume: 2016

    Topics: Female; Heart Arrest; Humans; Infant; Mydriatics; Ophthalmic Solutions; Phenylephrine; Retinopathy o

2016
Combination of 5% phenylephrine and 0.5% tropicamide eyedrops for pupil dilation in neonates is twice as effective as 0.5% tropicamide eyedrops alone.
    Acta ophthalmologica, 2017, Volume: 95, Issue:2

    Topics: Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up

2017
The local vasoconstriction of infant's skin following instillation of mydriatic eye drops.
    European journal of clinical pharmacology, 2010, Volume: 66, Issue:11

    Topics: Humans; Infant, Newborn; Infant, Premature; Mydriatics; Ophthalmic Solutions; Pallor; Phenylephrine;

2010
The pain response to mydriatic eyedrops in preterm infants.
    Journal of perinatology : official journal of the California Perinatal Association, 2013, Volume: 33, Issue:6

    Topics: Female; Humans; Infant, Newborn; Intensive Care Units, Neonatal; Male; Mydriatics; Ophthalmic Soluti

2013
Systemic manifestations in response to mydriasis and physical examination during screening for retinopathy of prematurity.
    Retina (Philadelphia, Pa.), 2004, Volume: 24, Issue:2

    Topics: Administration, Topical; Anesthetics, Local; Drug Administration Schedule; Eyelids; Humans; Infant,

2004
A comparison of mydriatic eyedrops in low-weight infants.
    Ophthalmology, 1984, Volume: 91, Issue:3

    Topics: Blood Pressure; Cyclopentolate; Drug Combinations; Humans; Infant, Low Birth Weight; Infant, Newborn

1984
Bilateral spontaneous pigment epithelial detachments in a premature neonate.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1994, Volume: 112, Issue:2

    Topics: Fundus Oculi; Humans; Infant, Newborn; Infant, Premature, Diseases; Phenylephrine; Pigment Epitheliu

1994