tropicamide has been researched along with Retinopathy of Prematurity in 18 studies
Tropicamide: One of the MUSCARINIC ANTAGONISTS with pharmacologic action similar to ATROPINE and used mainly as an ophthalmic parasympatholytic or mydriatic.
Retinopathy of Prematurity: A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To observe and compare the effects of pupil dilation between Mydrin-P and compound tropicamide in the screening of retinopathy of prematurity." | 7.80 | Comparison of the mydriatic effects of mydrin-P and compound tropicamide in the screening of retinopathy of prematurity. ( Lu, Y; Luo, S; Wan, Z; Ye, Z; Yin, X, 2014) |
| "A comprehensive literature search was performed in PubMed, Cochrane library, Trip database, and Scopus, using the key words: "mydriasis", "techniques", "mydriatics", "dilating drops", "retinopathy of prematurity", "ROP", "phenylephrine", "cyclopentolate", "tropicamide", "smaller mydriatic drops", "reduction in drop size" to February 2019." | 5.05 | Alternative mydriasis techniques for retinopathy of prematurity screening. ( Kokkali, S; Lithoxopoulou, M; Mataftsi, A; Prousali, E; Seliniotaki, AK; Soubasi, V; Ziakas, N, 2020) |
| "5% tropicamide and 5% phenylephrine eyedrops in order to achieve a proper dilation in premature infants undergoing screening for retinopathy of prematurity." | 3.85 | Combination of 5% phenylephrine and 0.5% tropicamide eyedrops for pupil dilation in neonates is twice as effective as 0.5% tropicamide eyedrops alone. ( Barjol, A; Degoumois, A; Denion, E; Lux, AL; Mouriaux, F, 2017) |
| " Two cases of necrotizing enterocolitis could be ascribed to the use of tropicamide with a doubtful and plausible intrinsic imputability according to French imputability criteria." | 3.81 | [Serious adverse side effects after pupillary dilation in preterm infants]. ( Denion, E; Fedrizzi, S; Guillois, B; Lux, AL; Mouriaux, F; Peyro-Saint-Paul, L, 2015) |
| " After pupil dilation with 1 % tropicamide and 10 % phenylephrine for retinal examination, acute elevation of intraocular pressure (IOP) was observed in the right eye." | 3.81 | Acute angle-closure glaucoma in retinopathy of prematurity following pupil dilation. ( Chang, SH; Lee, YS; Wu, SC; Wu, WC, 2015) |
| "To observe and compare the effects of pupil dilation between Mydrin-P and compound tropicamide in the screening of retinopathy of prematurity." | 3.80 | Comparison of the mydriatic effects of mydrin-P and compound tropicamide in the screening of retinopathy of prematurity. ( Lu, Y; Luo, S; Wan, Z; Ye, Z; Yin, X, 2014) |
| " Here, two cases are presented in which we observed skin pallor around the eyes after instillation of phenylephrine 2." | 3.76 | The local vasoconstriction of infant's skin following instillation of mydriatic eye drops. ( Alpay, A; Battal, F; Ermis, B; Sagdik, HM; Ugurbas, SC, 2010) |
| " Otherwise, adverse events did not differ after either administration technique." | 3.11 | Efficacy and safety of mydriatic microdrops for retinopathy of prematurity screening: an external pilot crossover randomized controlled trial. ( Diamanti, E; Georgiou, E; Haidich, AB; Lithoxopoulou, M; Mataftsi, A; Seliniotaki, AK; Talimtzi, P; Ziakas, N, 2022) |
| "To evaluate systemic adverse events after screening for retinopathy of prematurity (ROP) performed with mydriatic." | 1.62 | Systemic adverse events after screening of retinopathy of prematurity with mydriatic. ( Imamura, T; Kakinoki, M; Maruo, Y; Obata, S; Ohji, M; Yanagi, T, 2021) |
| "5% drop is effective and safe as mydriatic combination for retinopathy of prematurity screening." | 1.51 | Efficiency and safety of phenylephrine and tropicamide used in premature retinopathy: a prospective observational study. ( Alpay, A; Aydemir, C; Canturk Ugurbas, S, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.56) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 1 (5.56) | 29.6817 |
| 2010's | 10 (55.56) | 24.3611 |
| 2020's | 5 (27.78) | 2.80 |
| Authors | Studies |
|---|---|
| Obata, S | 1 |
| Imamura, T | 1 |
| Kakinoki, M | 1 |
| Yanagi, T | 1 |
| Maruo, Y | 1 |
| Ohji, M | 1 |
| Seliniotaki, AK | 2 |
| Lithoxopoulou, M | 2 |
| Talimtzi, P | 1 |
| Georgiou, E | 1 |
| Diamanti, E | 1 |
| Ziakas, N | 2 |
| Haidich, AB | 1 |
| Mataftsi, A | 2 |
| Alpay, A | 2 |
| Canturk Ugurbas, S | 1 |
| Aydemir, C | 1 |
| Mimori, K | 1 |
| Haneda, K | 1 |
| Shimizu, H | 1 |
| Yamashita, M | 1 |
| Tanaka, H | 1 |
| Prousali, E | 1 |
| Kokkali, S | 1 |
| Soubasi, V | 1 |
| Bembich, S | 1 |
| Demarini, S | 1 |
| Cont, G | 1 |
| Di Giusto, A | 1 |
| Mazzolai, M | 1 |
| Barbi, E | 1 |
| Risso, FM | 1 |
| Degirmencioglu, H | 1 |
| Oncel, MY | 1 |
| Calisici, E | 1 |
| Say, B | 1 |
| Uras, N | 1 |
| Dilmen, U | 1 |
| Lux, AL | 2 |
| Mouriaux, F | 2 |
| Guillois, B | 1 |
| Fedrizzi, S | 1 |
| Peyro-Saint-Paul, L | 1 |
| Denion, E | 2 |
| Luo, S | 1 |
| Wan, Z | 1 |
| Yin, X | 1 |
| Ye, Z | 1 |
| Lu, Y | 1 |
| Wu, SC | 1 |
| Lee, YS | 1 |
| Wu, WC | 1 |
| Chang, SH | 1 |
| Agrawal, Y | 1 |
| Patri, S | 1 |
| Kalavakunta, JK | 1 |
| Gupta, V | 1 |
| Degoumois, A | 1 |
| Barjol, A | 1 |
| Ermis, B | 1 |
| Ugurbas, SC | 1 |
| Battal, F | 1 |
| Sagdik, HM | 1 |
| Phamonvaechavan, P | 1 |
| Chutasmit, K | 1 |
| Damrongrak, P | 1 |
| Koukiatkul, S | 1 |
| Wongkiatkajorn, T | 1 |
| Ngerncham, S | 1 |
| Cohen, AM | 1 |
| Cook, N | 1 |
| Harris, MC | 1 |
| Ying, GS | 1 |
| Binenbaum, G | 1 |
| Rush, R | 1 |
| Rush, S | 1 |
| Nicolau, J | 1 |
| Chapman, K | 1 |
| Naqvi, M | 1 |
| Isenberg, S | 1 |
| Everett, S | 1 |
| Parelhoff, E | 1 |
| Berman, DH | 1 |
| Deutsch, JA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety of Mydriatic Microdrops Compared With Standard Drops for Retinopathy of Prematurity (ROP) Screening: a Pilot Randomized Clinical Trial[NCT04623684] | Phase 4 | 25 participants (Actual) | Interventional | 2020-03-24 | Completed | ||
| Efficiency and Safety of Phenylephrine and Tropicamide Used in Premature Retinopathy[NCT03448640] | 60 participants (Actual) | Observational | 2016-01-15 | Completed | |||
| Efficacy and Safety of Mydriatic Microdrops for Retinopathy Of Prematurity Screening: a Non-inferiority Crossover Randomized Controlled Trial (MyMiROPS Trial)[NCT05043077] | Phase 4 | 83 participants (Actual) | Interventional | 2021-09-07 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for tropicamide and Retinopathy of Prematurity
| Article | Year |
|---|---|
Alternative mydriasis techniques for retinopathy of prematurity screening.
Topics: Humans; Infant; Infant, Newborn; Infant, Premature; Mydriasis; Mydriatics; Ophthalmic Solutions; Phe | 2020 |
Alternative mydriasis techniques for retinopathy of prematurity screening.
Topics: Humans; Infant; Infant, Newborn; Infant, Premature; Mydriasis; Mydriatics; Ophthalmic Solutions; Phe | 2020 |
Alternative mydriasis techniques for retinopathy of prematurity screening.
Topics: Humans; Infant; Infant, Newborn; Infant, Premature; Mydriasis; Mydriatics; Ophthalmic Solutions; Phe | 2020 |
Alternative mydriasis techniques for retinopathy of prematurity screening.
Topics: Humans; Infant; Infant, Newborn; Infant, Premature; Mydriasis; Mydriatics; Ophthalmic Solutions; Phe | 2020 |
2 trials available for tropicamide and Retinopathy of Prematurity
| Article | Year |
|---|---|
Efficacy and safety of mydriatic microdrops for retinopathy of prematurity screening: an external pilot crossover randomized controlled trial.
Topics: Heart Rate; Humans; Infant; Infant, Newborn; Infant, Premature; Mydriatics; Ophthalmic Solutions; Ph | 2022 |
Comparison of the effectiveness of mydriasis by two instillation methods of combined 0.75% tropicamide and 2.5% phenylephrine eye drop in preterm infants.
Topics: Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Infant, Newborn; Infant, Premature; I | 2012 |
15 other studies available for tropicamide and Retinopathy of Prematurity
| Article | Year |
|---|---|
Systemic adverse events after screening of retinopathy of prematurity with mydriatic.
Topics: Body Weight; Drug-Related Side Effects and Adverse Reactions; Female; Gestational Age; Humans; Infan | 2021 |
Efficiency and safety of phenylephrine and tropicamide used in premature retinopathy: a prospective observational study.
Topics: Blood Pressure; Drug Therapy, Combination; Gestational Age; Humans; Infant, Newborn; Infant, Prematu | 2019 |
Necrotizing enterocolitis after an eye examination with mydriatics.
Topics: Constriction, Pathologic; Drug Combinations; Enterocolitis, Necrotizing; Humans; Infant, Extremely L | 2020 |
Effect of mydriatic administration on cerebral haemodynamics and oxygenation in preterm infants.
Topics: Administration, Ophthalmic; Brain; Cerebrovascular Circulation; Drug Combinations; Female; Gestation | 2020 |
Transient ileus associated with the use of mydriatics after screening for retinopathy of prematurity in a very low birth weight infant.
Topics: Adult; Drug Combinations; Female; Gestational Age; Humans; Ileus; Infant, Newborn; Infant, Very Low | 2014 |
[Serious adverse side effects after pupillary dilation in preterm infants].
Topics: Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Enterocol | 2015 |
Comparison of the mydriatic effects of mydrin-P and compound tropicamide in the screening of retinopathy of prematurity.
Topics: Humans; Infant, Newborn; Infant, Premature; Mydriasis; Mydriatics; Ophthalmic Solutions; Pupil; Reti | 2014 |
Acute angle-closure glaucoma in retinopathy of prematurity following pupil dilation.
Topics: Acute Disease; Child, Preschool; Drug Combinations; Female; Glaucoma, Angle-Closure; Humans; Intraoc | 2015 |
Retinopathy of prematurity screening leading to cardiopulmonary arrest: fatal complication of a benign procedure.
Topics: Female; Heart Arrest; Humans; Infant; Mydriatics; Ophthalmic Solutions; Phenylephrine; Retinopathy o | 2016 |
Combination of 5% phenylephrine and 0.5% tropicamide eyedrops for pupil dilation in neonates is twice as effective as 0.5% tropicamide eyedrops alone.
Topics: Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up | 2017 |
The local vasoconstriction of infant's skin following instillation of mydriatic eye drops.
Topics: Humans; Infant, Newborn; Infant, Premature; Mydriatics; Ophthalmic Solutions; Pallor; Phenylephrine; | 2010 |
The pain response to mydriatic eyedrops in preterm infants.
Topics: Female; Humans; Infant, Newborn; Intensive Care Units, Neonatal; Male; Mydriatics; Ophthalmic Soluti | 2013 |
Systemic manifestations in response to mydriasis and physical examination during screening for retinopathy of prematurity.
Topics: Administration, Topical; Anesthetics, Local; Drug Administration Schedule; Eyelids; Humans; Infant, | 2004 |
A comparison of mydriatic eyedrops in low-weight infants.
Topics: Blood Pressure; Cyclopentolate; Drug Combinations; Humans; Infant, Low Birth Weight; Infant, Newborn | 1984 |
Bilateral spontaneous pigment epithelial detachments in a premature neonate.
Topics: Fundus Oculi; Humans; Infant, Newborn; Infant, Premature, Diseases; Phenylephrine; Pigment Epitheliu | 1994 |