tropicamide has been researched along with Mydriasis in 31 studies
Tropicamide: One of the MUSCARINIC ANTAGONISTS with pharmacologic action similar to ATROPINE and used mainly as an ophthalmic parasympatholytic or mydriatic.
Mydriasis: Dilation of pupils to greater than 6 mm combined with failure of the pupils to constrict when stimulated with light. This condition may occur due to injury of the pupillary fibers in the oculomotor nerve, in acute angle-closure glaucoma, and in ADIE SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| "02%), and lidocaine (1%) intracamerally was used for mydriasis and analgesia." | 9.51 | Evaluation of efficacy of intracameral lidocaine and tropicamide injection in manual small-incision cataract surgery: A prospective clinical study. ( Bhat, KT; Heda, AS; Undre, AA; Wadgaonkar, SP, 2022) |
| "To determine the effects of tropicamide 1% on the refractive state of the adult equine globe and identify the most appropriate time period (in relation to mydriasis) to perform streak retinoscopy." | 9.19 | The effect of 1% tropicamide-induced mydriasis and cycloplegia on spherical refraction of the adult horse. ( Davidson, MG; Gilger, BC; McMullen, RJ, 2014) |
| "5% tropicamide and the resultant mydriasis on the anterior segment in normotensive dogs using ultrasound biomicroscopy." | 9.16 | Effect of mydriasis induced by topical instillations of 0.5% tropicamide on the anterior segment in normotensive dogs using ultrasound biomicroscopy. ( Dulaurent, A; Dulaurent, T; Goulle, F; Isard, PF; Mentek, M; Peiffer, RL, 2012) |
| "31%/lidocaine 1% in pediatric cataract surgery, a combination widely used in adult patients but still off-label in children." | 8.31 | Efficacy and safety of intraoperative use of tropicamide 0.02%/phenylephrine0.31%/lidocaine1% intracameral combination during pediatric cataract surgery. ( Caputo, R; Dellavalle, A; Lembo, A; Nucci, P; Pichi, F; Schiavetti, I; Serafino, M, 2023) |
| "To observe and compare the effects of pupil dilation between Mydrin-P and compound tropicamide in the screening of retinopathy of prematurity." | 7.80 | Comparison of the mydriatic effects of mydrin-P and compound tropicamide in the screening of retinopathy of prematurity. ( Lu, Y; Luo, S; Wan, Z; Ye, Z; Yin, X, 2014) |
| "Dapiprazole eye drops were applied 1 h after topical tropicamide or phenylephrine instillation in 30 elderly subjects." | 6.68 | [Dapiprazol antagonizes tropicamide- and phenylephrine-induced mydriasis in the elderly]. ( Höh, H; Ruprecht, KW; Warlich, M; Weik, R, 1995) |
| "Twenty patients with Alzheimer dementia and 20 control subjects were examined." | 6.68 | Response of the pupil to tropicamide is not a reliable test for Alzheimer disease. ( Brubaker, RF; FitzSimon, JS; Kokmen, E; McLaren, JW; Waring, SC, 1997) |
| "02%), and lidocaine (1%) intracamerally was used for mydriasis and analgesia." | 5.51 | Evaluation of efficacy of intracameral lidocaine and tropicamide injection in manual small-incision cataract surgery: A prospective clinical study. ( Bhat, KT; Heda, AS; Undre, AA; Wadgaonkar, SP, 2022) |
| "To determine the effects of tropicamide 1% on the refractive state of the adult equine globe and identify the most appropriate time period (in relation to mydriasis) to perform streak retinoscopy." | 5.19 | The effect of 1% tropicamide-induced mydriasis and cycloplegia on spherical refraction of the adult horse. ( Davidson, MG; Gilger, BC; McMullen, RJ, 2014) |
| "5% were evaluated by comparing the effects of two drugs given together and alone on the reversal of mydriasis induced by tropicamide (0." | 5.08 | The additive miotic effects of dapiprazole and pilocarpine. ( Geyer, O; Lazar, M; Loewenstein, A; Neudorfer, M; Shalmon, B, 1995) |
| "A comprehensive literature search was performed in PubMed, Cochrane library, Trip database, and Scopus, using the key words: "mydriasis", "techniques", "mydriatics", "dilating drops", "retinopathy of prematurity", "ROP", "phenylephrine", "cyclopentolate", "tropicamide", "smaller mydriatic drops", "reduction in drop size" to February 2019." | 5.05 | Alternative mydriasis techniques for retinopathy of prematurity screening. ( Kokkali, S; Lithoxopoulou, M; Mataftsi, A; Prousali, E; Seliniotaki, AK; Soubasi, V; Ziakas, N, 2020) |
| "The risk of inducing acute glaucoma following mydriasis with tropicamide alone is close to zero, no case being identified." | 4.80 | Mydriasis and glaucoma: exploding the myth. A systematic review. ( Pandit, RJ; Taylor, R, 2000) |
| "We evaluated, in a real-life setting, the effect of Mydrane® (ready-to-use combination of tropicamide, phenylephrine hydrochloride and lidocaine, injected into the anterior chamber at the beginning of cataract surgery to induce mydriasis and intraocular anaesthesia) on the pupil diameter during cataract surgery in patients with a preoperative pupil diameter <6 mm after the use of topical mydriatics." | 4.31 | Pupil diameter during cataract surgery after intracameral injection of the first ready-to-use combination of mydriatics and anaesthetic at the beginning of surgery in patients with a preoperative pupil diameter <6 mm. ( Grabska-Liberek, I; Jurowski, P; Kęcik, D; Kopacz, D; Mianowska, K; Mrukwa-Kominek, E; Omulecki, W; Romaniuk, W; Romanowska-Dixon, B; Szaflik, J; Szaflik, JP, 2023) |
| "31%/lidocaine 1% in pediatric cataract surgery, a combination widely used in adult patients but still off-label in children." | 4.31 | Efficacy and safety of intraoperative use of tropicamide 0.02%/phenylephrine0.31%/lidocaine1% intracameral combination during pediatric cataract surgery. ( Caputo, R; Dellavalle, A; Lembo, A; Nucci, P; Pichi, F; Schiavetti, I; Serafino, M, 2023) |
| "To observe and compare the effects of pupil dilation between Mydrin-P and compound tropicamide in the screening of retinopathy of prematurity." | 3.80 | Comparison of the mydriatic effects of mydrin-P and compound tropicamide in the screening of retinopathy of prematurity. ( Lu, Y; Luo, S; Wan, Z; Ye, Z; Yin, X, 2014) |
| "Mydrane is an effective and safe alternative to standard eye drops for initiating and maintaining intraoperative mydriasis and analgesia." | 2.82 | Evaluation of the efficacy and safety of a standardised intracameral combination of mydriatics and anaesthetics for cataract surgery. ( Alió, J; Behndig, A; Cochener, B; Colin, J; Findl, O; Hartani, D; Labetoulle, M; Lazreg, S; Lobo, C; Malecaze, F; Tassignon, MJ, 2016) |
| "Dapiprazole eye drops were applied 1 h after topical tropicamide or phenylephrine instillation in 30 elderly subjects." | 2.68 | [Dapiprazol antagonizes tropicamide- and phenylephrine-induced mydriasis in the elderly]. ( Höh, H; Ruprecht, KW; Warlich, M; Weik, R, 1995) |
| "Twenty patients with Alzheimer dementia and 20 control subjects were examined." | 2.68 | Response of the pupil to tropicamide is not a reliable test for Alzheimer disease. ( Brubaker, RF; FitzSimon, JS; Kokmen, E; McLaren, JW; Waring, SC, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.23) | 18.7374 |
| 1990's | 7 (22.58) | 18.2507 |
| 2000's | 2 (6.45) | 29.6817 |
| 2010's | 9 (29.03) | 24.3611 |
| 2020's | 12 (38.71) | 2.80 |
| Authors | Studies |
|---|---|
| Kuang, TM | 1 |
| Tsai, SY | 1 |
| Liu, CJ | 1 |
| Lee, SM | 1 |
| Chou, P | 1 |
| Zhang, W | 1 |
| Guo, Y | 1 |
| Chen, Y | 1 |
| Wu, W | 1 |
| Li, J | 1 |
| Kęcik, D | 1 |
| Grabska-Liberek, I | 1 |
| Jurowski, P | 1 |
| Mrukwa-Kominek, E | 1 |
| Omulecki, W | 1 |
| Romanowska-Dixon, B | 1 |
| Szaflik, JP | 1 |
| Romaniuk, W | 1 |
| Szaflik, J | 1 |
| Kopacz, D | 1 |
| Mianowska, K | 1 |
| Nucci, P | 1 |
| Lembo, A | 1 |
| Caputo, R | 1 |
| Dellavalle, A | 1 |
| Serafino, M | 1 |
| Schiavetti, I | 1 |
| Pichi, F | 1 |
| Bhat, KT | 1 |
| Wadgaonkar, SP | 1 |
| Undre, AA | 1 |
| Heda, AS | 1 |
| Prasher, P | 1 |
| Vig, VK | 1 |
| Singh, B | 1 |
| Sharma, R | 1 |
| Sharma, A | 1 |
| Cirla, A | 1 |
| Drigo, M | 1 |
| Ballerini, L | 1 |
| Trucco, E | 1 |
| Barsotti, G | 1 |
| Cheng, M | 1 |
| Liu, S | 1 |
| Chen, X | 1 |
| Zhou, X | 2 |
| Wang, X | 1 |
| Seliniotaki, AK | 1 |
| Prousali, E | 1 |
| Lithoxopoulou, M | 1 |
| Kokkali, S | 1 |
| Ziakas, N | 1 |
| Soubasi, V | 1 |
| Mataftsi, A | 1 |
| Rashidi, N | 1 |
| Pant, AD | 1 |
| Salinas, SD | 1 |
| Shah, M | 1 |
| Thomas, VS | 1 |
| Zhang, G | 1 |
| Dorairaj, S | 1 |
| Amini, R | 1 |
| Wirta, DL | 1 |
| Walters, TR | 1 |
| Flynn, WJ | 1 |
| Rathi, S | 1 |
| Ianchulev, T | 1 |
| Pumphrey, SA | 1 |
| Moon, Y | 1 |
| Francis, JM | 1 |
| Williams-Fritze, MJ | 1 |
| Lee-Parritz, D | 1 |
| Nuijts, RMMA | 1 |
| Mencucci, R | 1 |
| Viaud-Quentric, K | 1 |
| Elena, PP | 1 |
| Olmière, C | 1 |
| Behndig, A | 2 |
| Koehler, K | 1 |
| Sehner, S | 1 |
| Riemer, M | 1 |
| Gehl, A | 1 |
| Raupach, T | 1 |
| Anders, S | 1 |
| Davey, K | 1 |
| Chang, B | 1 |
| Purslow, C | 1 |
| Clay, E | 1 |
| Vataire, AL | 1 |
| Sherman, AE | 1 |
| Shaw, MM | 1 |
| Ralay-Ranaivo, H | 1 |
| Rahmani, B | 1 |
| McMullen, RJ | 1 |
| Davidson, MG | 1 |
| Gilger, BC | 1 |
| Oltulu, R | 1 |
| Satirtav, G | 1 |
| Altunkaya, O | 1 |
| Bitirgen, G | 1 |
| Okka, M | 1 |
| Luo, S | 1 |
| Wan, Z | 1 |
| Yin, X | 1 |
| Ye, Z | 1 |
| Lu, Y | 1 |
| Labetoulle, M | 1 |
| Findl, O | 1 |
| Malecaze, F | 1 |
| Alió, J | 1 |
| Cochener, B | 1 |
| Lobo, C | 1 |
| Lazreg, S | 1 |
| Hartani, D | 1 |
| Colin, J | 1 |
| Tassignon, MJ | 1 |
| Dulaurent, T | 1 |
| Goulle, F | 1 |
| Dulaurent, A | 1 |
| Mentek, M | 1 |
| Peiffer, RL | 1 |
| Isard, PF | 1 |
| TOMIYAMA, S | 1 |
| NAKAJIMA, A | 1 |
| KANKI, K | 1 |
| YOSHIMOTO, M | 1 |
| KONNO, N | 1 |
| Hirowatari, T | 1 |
| Tokuda, K | 1 |
| Kamei, Y | 1 |
| Miyazaki, Y | 1 |
| Matsubara, M | 1 |
| Geyer, O | 1 |
| Loewenstein, A | 1 |
| Shalmon, B | 1 |
| Neudorfer, M | 1 |
| Lazar, M | 1 |
| Warlich, M | 1 |
| Weik, R | 1 |
| Höh, H | 1 |
| Ruprecht, KW | 1 |
| Smith, RD | 1 |
| Grzelak, ME | 1 |
| Belanger, B | 1 |
| Morgan, CA | 1 |
| Wyatt, HJ | 1 |
| FitzSimon, JS | 1 |
| Waring, SC | 1 |
| Kokmen, E | 1 |
| McLaren, JW | 1 |
| Brubaker, RF | 1 |
| Higuchi, S | 1 |
| Matsushita, S | 1 |
| Hasegawa, Y | 1 |
| Muramatsu, T | 1 |
| Arai, H | 1 |
| Hayashida, M | 1 |
| Pandit, RJ | 1 |
| Taylor, R | 1 |
| Power, WJ | 1 |
| Hope-Ross, M | 1 |
| Mooney, DJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety of Mydriatic Microdrops for Retinopathy Of Prematurity Screening: a Non-inferiority Crossover Randomized Controlled Trial (MyMiROPS Trial)[NCT05043077] | Phase 4 | 83 participants (Actual) | Interventional | 2021-09-07 | Completed | ||
| Efficacy and Safety of Mydriatic Microdrops Compared With Standard Drops for Retinopathy of Prematurity (ROP) Screening: a Pilot Randomized Clinical Trial[NCT04623684] | Phase 4 | 25 participants (Actual) | Interventional | 2020-03-24 | Completed | ||
| Efficacy and Safety Assessment of Intracameral Injection of T2380 in Cataract Surgery Versus Reference Group (Topical Mydriatics and Anaesthetic)[NCT02101359] | Phase 3 | 609 participants (Actual) | Interventional | 2011-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT02101359)
Timeframe: Day 0
| Intervention | percentage of responders (Number) |
|---|---|
| T2380 | 98.9 |
| Reference Group | 94.7 |
2 reviews available for tropicamide and Mydriasis
| Article | Year |
|---|---|
Alternative mydriasis techniques for retinopathy of prematurity screening.
Topics: Humans; Infant; Infant, Newborn; Infant, Premature; Mydriasis; Mydriatics; Ophthalmic Solutions; Phe | 2020 |
Alternative mydriasis techniques for retinopathy of prematurity screening.
Topics: Humans; Infant; Infant, Newborn; Infant, Premature; Mydriasis; Mydriatics; Ophthalmic Solutions; Phe | 2020 |
Alternative mydriasis techniques for retinopathy of prematurity screening.
Topics: Humans; Infant; Infant, Newborn; Infant, Premature; Mydriasis; Mydriatics; Ophthalmic Solutions; Phe | 2020 |
Alternative mydriasis techniques for retinopathy of prematurity screening.
Topics: Humans; Infant; Infant, Newborn; Infant, Premature; Mydriasis; Mydriatics; Ophthalmic Solutions; Phe | 2020 |
Mydriasis and glaucoma: exploding the myth. A systematic review.
Topics: Glaucoma; Humans; Mydriasis; Mydriatics; Risk Factors; Safety; Tropicamide | 2000 |
10 trials available for tropicamide and Mydriasis
| Article | Year |
|---|---|
Evaluation of efficacy of intracameral lidocaine and tropicamide injection in manual small-incision cataract surgery: A prospective clinical study.
Topics: Cataract; Humans; Lidocaine; Mydriasis; Mydriatics; Phacoemulsification; Phenylephrine; Prospective | 2022 |
Mydriasis with micro-array print touch-free tropicamide-phenylephrine fixed combination MIST: pooled randomized Phase III trials.
Topics: Humans; Mydriasis; Ophthalmic Solutions; Phenylephrine; Prospective Studies; Pupil; Tropicamide | 2021 |
The effect of 1% tropicamide-induced mydriasis and cycloplegia on spherical refraction of the adult horse.
Topics: Animals; Eye; Female; Horses; Muscarinic Antagonists; Mydriasis; Tropicamide | 2014 |
Effect of mydriasis induced by topical 0.5% tropicamide instillation on the corneal biomechanical properties in healthy individuals measured by ocular response analyzer.
Topics: Administration, Topical; Adolescent; Adult; Aged; Cornea; Female; Healthy Volunteers; Humans; Intrao | 2015 |
Evaluation of the efficacy and safety of a standardised intracameral combination of mydriatics and anaesthetics for cataract surgery.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Dose-Response Relationship, Drug; Drug Therapy, | 2016 |
Effect of mydriasis induced by topical instillations of 0.5% tropicamide on the anterior segment in normotensive dogs using ultrasound biomicroscopy.
Topics: Animals; Dogs; Female; Male; Mydriasis; Mydriatics; Tropicamide | 2012 |
Evaluation of a new preoperative ophthalmic solution.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Diabet | 2005 |
The additive miotic effects of dapiprazole and pilocarpine.
Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Aged; Aged, 80 and over; Double-Blind Method; Drug | 1995 |
[Dapiprazol antagonizes tropicamide- and phenylephrine-induced mydriasis in the elderly].
Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Female; Humans; Intraocular Pressure; Male; M | 1995 |
Response of the pupil to tropicamide is not a reliable test for Alzheimer disease.
Topics: Aged; Alzheimer Disease; Female; Humans; Male; Mydriasis; Placebos; Pupil; Tropicamide | 1997 |
19 other studies available for tropicamide and Mydriasis
| Article | Year |
|---|---|
Changes in intraocular pressure after pharmacological pupil dilatation in an elderly Chinese population in Taiwan: The Shihpai eye study.
Topics: Aged; China; Cross-Sectional Studies; Dilatation; Glaucoma, Open-Angle; Humans; Intraocular Pressure | 2022 |
Analysis of pupil size by repeat dilation at shrinkage stage.
Topics: Dilatation; Humans; Mydriasis; Mydriatics; Phenylephrine; Prospective Studies; Pupil; Tropicamide | 2022 |
Pupil diameter during cataract surgery after intracameral injection of the first ready-to-use combination of mydriatics and anaesthetic at the beginning of surgery in patients with a preoperative pupil diameter <6 mm.
Topics: Anesthetics; Cataract; Humans; Lidocaine; Mydriasis; Mydriatics; Ophthalmic Solutions; Phacoemulsifi | 2023 |
Efficacy and safety of intraoperative use of tropicamide 0.02%/phenylephrine0.31%/lidocaine1% intracameral combination during pediatric cataract surgery.
Topics: Adult; Cataract; Child; Humans; Lidocaine; Mydriasis; Mydriatics; Ophthalmology; Phacoemulsification | 2023 |
Effect of mydriatic eye drops (combined 0.8% tropicamide and 5% phenylephrine) on the measurements of corneal parameters using Pentacam.
Topics: Adult; Cornea; Humans; Mydriasis; Mydriatics; Ophthalmic Solutions; Phenylephrine; Tropicamide | 2023 |
Effects of pupil dilation with topical 0.5% tropicamide on retinal vascular parameters assessed by VAMPIRE® software in healthy cats.
Topics: Animals; Cat Diseases; Cats; Mydriasis; Mydriatics; Pupil; Software; Tropicamide | 2023 |
Pharmacological Accommodative Changes of the Anterior Segment and Its Impact on the Vault in Implantable Collamer Lens Implantation.
Topics: Adult; Humans; Lenses, Intraocular; Miosis; Mydriasis; Pilocarpine; Tropicamide | 2023 |
Iris stromal cell nuclei deform to more elongated shapes during pharmacologically-induced miosis and mydriasis.
Topics: Animals; Disease Models, Animal; Drug Combinations; Iris; Microscopy, Confocal; Miosis; Miotics; Myd | 2021 |
Duration of Mydriasis Produced by 0.5% and 1% Tropicamide in Sprague-Dawley Rats.
Topics: Animals; Female; Mydriasis; Mydriatics; Pupil; Rats; Rats, Sprague-Dawley; Tropicamide | 2021 |
Ocular tolerance in rabbits after intracameral administration of a fixed combination of tropicamide, phenylephrine, and lidocaine with and without rinsing.
Topics: Animals; Endothelium, Corneal; Lidocaine; Mydriasis; Mydriatics; Phenylephrine; Pupil; Rabbits; Trop | 2017 |
Post-mortem chemical excitability of the iris should not be used for forensic death time diagnosis.
Topics: Acetylcholine; Adult; Aged; Aged, 80 and over; Case-Control Studies; Female; Humans; Injections; Iri | 2018 |
Budget impact model of Mydrane®, a new intracameral injectable used for intra-operative mydriasis, from a UK hospital perspective.
Topics: Anesthetics, Local; Budgets; Cost-Benefit Analysis; Drug Costs; Hospital Costs; Humans; Lidocaine; M | 2018 |
Tropicamide has limited clinical effect on cycloplegia and mydriasis when combined with cyclopentolate and phenylephrine.
Topics: Child; Child, Preschool; Cyclopentolate; Drug Therapy, Combination; Female; Humans; Male; Mydriasis; | 2019 |
Comparison of the mydriatic effects of mydrin-P and compound tropicamide in the screening of retinopathy of prematurity.
Topics: Humans; Infant, Newborn; Infant, Premature; Mydriasis; Mydriatics; Ophthalmic Solutions; Pupil; Reti | 2014 |
[On the effects of the surface anesthesia eye drop, 0.5 per cent Ofsein and the mydriasis eye drop, Mydriaticum "Roche"].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthetics; Anesthetics, Local; Humans; Mydriasis; | 1961 |
The effects of tropicamide on mydriasis in young rats exhibiting a natural deficit in passive-avoidance responding.
Topics: Aging; Animals; Avoidance Learning; Dose-Response Relationship, Drug; Injections, Subcutaneous; Musc | 1996 |
Ocular pharmacokinetics and convectional flow: evidence from spatio-temporal analysis of mydriasis.
Topics: Anterior Chamber; Aqueous Humor; Body Temperature; Cornea; Humans; Iris; Mydriasis; Mydriatics; Phen | 1996 |
Apolipoprotein E epsilon 4 allele and pupillary response to tropicamide.
Topics: Aging; Alleles; Alzheimer Disease; Apolipoprotein E4; Apolipoproteins E; Female; Genotype; Humans; M | 1997 |
Preoperative pupil fatigue.
Topics: Aged; Aged, 80 and over; Cataract Extraction; Cyclopentolate; Female; Humans; Male; Middle Aged; Myd | 1992 |