Page last updated: 2024-11-05

tropicamide and Cataract

tropicamide has been researched along with Cataract in 15 studies

Tropicamide: One of the MUSCARINIC ANTAGONISTS with pharmacologic action similar to ATROPINE and used mainly as an ophthalmic parasympatholytic or mydriatic.

Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"02%), and lidocaine (1%) intracamerally was used for mydriasis and analgesia."9.51Evaluation of efficacy of intracameral lidocaine and tropicamide injection in manual small-incision cataract surgery: A prospective clinical study. ( Bhat, KT; Heda, AS; Undre, AA; Wadgaonkar, SP, 2022)
"31%/lidocaine 1% in pediatric cataract surgery, a combination widely used in adult patients but still off-label in children."8.31Efficacy and safety of intraoperative use of tropicamide 0.02%/phenylephrine0.31%/lidocaine1% intracameral combination during pediatric cataract surgery. ( Caputo, R; Dellavalle, A; Lembo, A; Nucci, P; Pichi, F; Schiavetti, I; Serafino, M, 2023)
"02%), and lidocaine (1%) intracamerally was used for mydriasis and analgesia."5.51Evaluation of efficacy of intracameral lidocaine and tropicamide injection in manual small-incision cataract surgery: A prospective clinical study. ( Bhat, KT; Heda, AS; Undre, AA; Wadgaonkar, SP, 2022)
"31% and lidocaine 1%) and mydriatic drops (tropicamide 1% and phenylephrine 10%) used for cataract surgery in terms of efficacy in pupil dilation and impact on corneal endothelial cell density (CD) and central corneal thickness (CCT)."5.34Mydrane intracameral injection site can be an alternative to mydriatic drops instillation in cataract surgery. ( Bolsega-Pacud, J; Kubicka-Trzaska, A; Markiewicz, A; Nazim-Lipski, G; Romanowska-Dixon, B, 2020)
"We evaluated, in a real-life setting, the effect of Mydrane® (ready-to-use combination of tropicamide, phenylephrine hydrochloride and lidocaine, injected into the anterior chamber at the beginning of cataract surgery to induce mydriasis and intraocular anaesthesia) on the pupil diameter during cataract surgery in patients with a preoperative pupil diameter <6 mm after the use of topical mydriatics."4.31Pupil diameter during cataract surgery after intracameral injection of the first ready-to-use combination of mydriatics and anaesthetic at the beginning of surgery in patients with a preoperative pupil diameter <6 mm. ( Grabska-Liberek, I; Jurowski, P; Kęcik, D; Kopacz, D; Mianowska, K; Mrukwa-Kominek, E; Omulecki, W; Romaniuk, W; Romanowska-Dixon, B; Szaflik, J; Szaflik, JP, 2023)
"31%/lidocaine 1% in pediatric cataract surgery, a combination widely used in adult patients but still off-label in children."4.31Efficacy and safety of intraoperative use of tropicamide 0.02%/phenylephrine0.31%/lidocaine1% intracameral combination during pediatric cataract surgery. ( Caputo, R; Dellavalle, A; Lembo, A; Nucci, P; Pichi, F; Schiavetti, I; Serafino, M, 2023)
" Pupils were dilated with phenylephrine alone for cataract identification because there were concerns that patient discomfort, due to cycloplegia occurring with the usual dilating agents of tropicamide and phenylephrine, may influence future compliance in an associated intervention study."3.70Comparative pupil dilation using phenylephrine alone or in combination with tropicamide. ( Battistutta, D; Eyeson-Annan, ML; Green, A; Hirst, LW, 1998)
"5% tropicamide and of 10% phenylephrine hydrochloride instilled after routine applanation tonometry gave consistent pupil dilatation in a population with cataract studied over 5 years."3.68Reproducibility of mydriasis. ( Maclean, H, 1992)
"Tropicamide was rapidly absorbed systemically with the mean peak concentration in plasma being 2."1.29Systemic absorption and anticholinergic activity of topically applied tropicamide. ( Iisalo, E; Kaila, T; Saari, KM; Vuori, ML, 1994)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.67)18.7374
1990's4 (26.67)18.2507
2000's1 (6.67)29.6817
2010's4 (26.67)24.3611
2020's5 (33.33)2.80

Authors

AuthorsStudies
Kęcik, D1
Grabska-Liberek, I1
Jurowski, P1
Mrukwa-Kominek, E1
Omulecki, W1
Romanowska-Dixon, B2
Szaflik, JP1
Romaniuk, W1
Szaflik, J1
Kopacz, D1
Mianowska, K1
Nucci, P1
Lembo, A1
Caputo, R1
Dellavalle, A1
Serafino, M1
Schiavetti, I1
Pichi, F1
Bhat, KT1
Wadgaonkar, SP1
Undre, AA1
Heda, AS1
Deeks, ED1
Nazim-Lipski, G1
Bolsega-Pacud, J1
Kubicka-Trzaska, A1
Markiewicz, A1
Chen, X1
Yan, H1
Chen, Y1
Li, G1
Bin, Y1
Zhou, X1
Arimura, S1
Takamura, Y1
Takihara, Y1
Matsumura, T1
Tomomatsu, T1
Inatani, M1
Shafiq, A1
Arriola-Villalobos, P1
Almendral-Gómez, J1
Garzón, N1
Ruiz-Medrano, J1
Fernández-Pérez, C1
Martínez-de-la-Casa, JM1
Díaz-Valle, D1
Wiggins, MN1
Irak-Dersu, I1
Turner, SD1
Thostenson, JD1
Vuori, ML1
Kaila, T1
Iisalo, E1
Saari, KM1
Eyeson-Annan, ML1
Hirst, LW1
Battistutta, D1
Green, A1
Hoh, ST1
Greenfield, DS1
Liebmann, JM1
Hillenkamp, J1
Ishikawa, H1
Mistlberger, A1
Lim, AS1
Ritch, R1
Maclean, H1
Bosse, JC1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of Light Sensitivity and Visual Acuity Changes as Consequence of Rigid Gas Permeable (RGP) Scleral Contact Lenses With a Passive Artificial Iris[NCT04040790]10 participants (Actual)Interventional2019-09-16Terminated (stopped due to Several reasons: Financing ended before all study assessments were performed, covid-19 delayed design, production and shipment of IMD, experience gained during the study made it clear that lens design should be changed)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

4 trials available for tropicamide and Cataract

ArticleYear
Evaluation of efficacy of intracameral lidocaine and tropicamide injection in manual small-incision cataract surgery: A prospective clinical study.
    Indian journal of ophthalmology, 2022, Volume: 70, Issue:11

    Topics: Cataract; Humans; Lidocaine; Mydriasis; Mydriatics; Phacoemulsification; Phenylephrine; Prospective

2022
Tropicamide/Phenylephrine/Lidocaine Intracameral Injection: A Review in Cataract Surgery.
    Clinical drug investigation, 2019, Volume: 39, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Cataract; Cataract Extraction; Drug Combinations; Drug Therapy, Comb

2019
Mydrane intracameral injection site can be an alternative to mydriatic drops instillation in cataract surgery.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2020, Volume: 71, Issue:2

    Topics: Aged; Aged, 80 and over; Cataract; Cataract Extraction; Female; Humans; Injections, Intraocular; Lid

2020
Effect of pharmacological pupil dilation on measurements and iol power calculation made using the new swept-source optical coherence tomography-based optical biometer.
    Journal francais d'ophtalmologie, 2016, Volume: 39, Issue:10

    Topics: Aged; Aged, 80 and over; Axial Length, Eye; Biometry; Cataract; Dilatation; Female; Humans; Lens, Cr

2016

Other Studies

11 other studies available for tropicamide and Cataract

ArticleYear
Pupil diameter during cataract surgery after intracameral injection of the first ready-to-use combination of mydriatics and anaesthetic at the beginning of surgery in patients with a preoperative pupil diameter <6 mm.
    Acta ophthalmologica, 2023, Volume: 101, Issue:1

    Topics: Anesthetics; Cataract; Humans; Lidocaine; Mydriasis; Mydriatics; Ophthalmic Solutions; Phacoemulsifi

2023
Efficacy and safety of intraoperative use of tropicamide 0.02%/phenylephrine0.31%/lidocaine1% intracameral combination during pediatric cataract surgery.
    International ophthalmology, 2023, Volume: 43, Issue:3

    Topics: Adult; Cataract; Child; Humans; Lidocaine; Mydriasis; Mydriatics; Ophthalmology; Phacoemulsification

2023
Moderate oxidative stress promotes epithelial-mesenchymal transition in the lens epithelial cells via the TGF-β/Smad and Wnt/β-catenin pathways.
    Molecular and cellular biochemistry, 2021, Volume: 476, Issue:3

    Topics: Animals; Antioxidants; beta Catenin; Capsule Opacification; Cataract; Cell Proliferation; Cell Survi

2021
Determinants of anterior chamber angle narrowing after mydriasis in the patients with cataract.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2015, Volume: 253, Issue:2

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Anterior Chamber; Cataract; Female; Glaucoma, Angle-C

2015
Seeing red in young children: the importance of the red reflex.
    The British journal of general practice : the journal of the Royal College of General Practitioners, 2015, Volume: 65, Issue:633

    Topics: Cataract; Diagnosis, Differential; Humans; Infant; Mydriatics; Ophthalmoscopy; Reflex, Pupillary; Re

2015
Glare testing in patients with cataract after dilation.
    Ophthalmology, 2009, Volume: 116, Issue:7

    Topics: Aged; Aged, 80 and over; Cataract; Drug Combinations; Female; Glare; Humans; Male; Middle Aged; Mydr

2009
Systemic absorption and anticholinergic activity of topically applied tropicamide.
    Journal of ocular pharmacology, 1994,Summer, Volume: 10, Issue:2

    Topics: Absorption; Administration, Topical; Aged; Animals; Brain; Cataract; Choline; Female; Glaucoma, Open

1994
Comparative pupil dilation using phenylephrine alone or in combination with tropicamide.
    Ophthalmology, 1998, Volume: 105, Issue:4

    Topics: Accommodation, Ocular; Adult; Aged; Cataract; Drug Combinations; Female; Humans; Male; Middle Aged;

1998
Effect of pupillary dilation on retinal nerve fiber layer thickness as measured by scanning laser polarimetry in eyes with and without cataract.
    Journal of glaucoma, 1999, Volume: 8, Issue:3

    Topics: Adult; Aged; Cataract; Diagnostic Techniques, Ophthalmological; Humans; Lasers; Middle Aged; Mydriat

1999
Reproducibility of mydriasis.
    Ophthalmic research, 1992, Volume: 24 Suppl 1

    Topics: Cataract; Follow-Up Studies; Humans; Image Processing, Computer-Assisted; Phenylephrine; Photography

1992
Potential visual acuity measured with and without pupil dilation.
    Optometry and vision science : official publication of the American Academy of Optometry, 1989, Volume: 66, Issue:8

    Topics: Aged; Cataract; Humans; Interferometry; Iris; Middle Aged; Phenylephrine; Pupil; Tropicamide; Visual

1989