tropicamide has been researched along with Acute Confusional Senile Dementia in 36 studies
Tropicamide: One of the MUSCARINIC ANTAGONISTS with pharmacologic action similar to ATROPINE and used mainly as an ophthalmic parasympatholytic or mydriatic.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether pupillary responses to dilute tropicamide could be used as a diagnostic test for Alzheimer disease (AD)." | 9.08 | Pupillary response to tropicamide in patients with Alzheimer disease. ( Edelhauser, HF; Geis, TC; Green, RC; Loupe, DN; Lynn, MJ; Newman, NJ; WIlliams, KK, 1996) |
| "The extent of pupil dilation after instillation of a dilute tropicamide solution was proposed as a noninvasive neurobiological diagnostic test for Alzheimer disease (AD)." | 9.08 | Pupil dilation to tropicamide is not specific for Alzheimer disease. ( Graefe, K; Growdon, JH; Hayden, D; Schoenfeld, D; Tennis, M; Wray, SH, 1997) |
| "The anticholinergic agent tropicamide causes a significantly greater change in the pupil diameter of patients with Alzheimer's disease (AD) than in that of patients with alcoholic or vascular dementia or in normal controls." | 7.69 | Pupillary response to tropicamide in Japanese patients with alcoholic dementia, Alzheimer's disease, and vascular dementia. ( Arai, H; Hasegawa, Y; Higuchi, S; Matsushita, S; Muramatsu, T, 1997) |
| "Twenty patients with Alzheimer dementia and 20 control subjects were examined." | 6.68 | Response of the pupil to tropicamide is not a reliable test for Alzheimer disease. ( Brubaker, RF; FitzSimon, JS; Kokmen, E; McLaren, JW; Waring, SC, 1997) |
| "To determine whether pupillary responses to dilute tropicamide could be used as a diagnostic test for Alzheimer disease (AD)." | 5.08 | Pupillary response to tropicamide in patients with Alzheimer disease. ( Edelhauser, HF; Geis, TC; Green, RC; Loupe, DN; Lynn, MJ; Newman, NJ; WIlliams, KK, 1996) |
| "The extent of pupil dilation after instillation of a dilute tropicamide solution was proposed as a noninvasive neurobiological diagnostic test for Alzheimer disease (AD)." | 5.08 | Pupil dilation to tropicamide is not specific for Alzheimer disease. ( Graefe, K; Growdon, JH; Hayden, D; Schoenfeld, D; Tennis, M; Wray, SH, 1997) |
| "01% tropicamide receptor test allows to discriminate between different dementia types of, as demonstrated in our study." | 3.75 | [The pupillary response test as a method to differentiate various types of dementia]. ( Frottier, P; Grünberger, J; Haushofer, M; Prause, W; Rainer, M; Saletu, B; Stöhr, H, 2009) |
| "The anticholinergic agent tropicamide causes a significantly greater change in the pupil diameter of patients with Alzheimer's disease (AD) than in that of patients with alcoholic or vascular dementia or in normal controls." | 3.69 | Pupillary response to tropicamide in Japanese patients with alcoholic dementia, Alzheimer's disease, and vascular dementia. ( Arai, H; Hasegawa, Y; Higuchi, S; Matsushita, S; Muramatsu, T, 1997) |
| "Diagnostic tests for Alzheimer's disease (AD) involving tropicamide blockade of cholinergic oculomotor functions were examined in AD patients (n=15), Parkinson's disease (PD) patients (n=15), and non-clinical control (NC) participants (n=15)." | 2.71 | Tropicamide effects on pupil size and pupillary light reflexes in Alzheimer's and Parkinson's disease. ( Galasko, D; Granholm, E; Morris, S; Rogers, E; Shults, C; Vukov, B, 2003) |
| "Patients with Alzheimer's disease (AD) reportedly exhibit greater pupillary dilation than healthy subjects in response to tropicamide." | 2.69 | Is videopupillography useful in the diagnosis of Alzheimer's disease? ( Bogetto, C; Ferrario, E; Molaschi, M; Nuzzi, R; Varetto, O; Villa, L, 1998) |
| "Twenty patients with Alzheimer dementia and 20 control subjects were examined." | 2.68 | Response of the pupil to tropicamide is not a reliable test for Alzheimer disease. ( Brubaker, RF; FitzSimon, JS; Kokmen, E; McLaren, JW; Waring, SC, 1997) |
| "Currently Alzheimer's disease, which affects more than 20 million people worldwide, can only be definitely diagnosed by histological examination of brain tissue obtained at autopsy or biopsy." | 2.67 | A potential noninvasive neurobiological test for Alzheimer's disease. ( Daffner, KR; Dressler, D; Mesulam, M; Potter, H; Ransil, BI; Rentz, D; Scinto, LF; Weintraub, S, 1994) |
| "Patients suffering from Alzheimer's disease (AD) may show increased sensitivity to tropicamide, a muscarinic cholinoceptor antagonist." | 1.33 | Why patients with Alzheimer's disease may show increased sensitivity to tropicamide eye drops: role of locus coeruleus. ( Bradshaw, CM; Hou, RH; Langley, RW; Raisi, M; Samuels, ER; Szabadi, E, 2006) |
| " Despite a limited sample size in the present study, our results indicate that the pupil dilation assay by tropicamide is not an effective diagnostic tool for AD, and it may be modulated by different gene dosage of ApoE epsilon 4." | 1.29 | Pupil dilatation assay by tropicamide is modulated by apolipoprotein E epsilon 4 allele dosage in Alzheimer's disease. ( Arai, H; Higuchi, S; Mochizuki, H; Nakagawa, T; Sasaki, H; Terajima, M, 1996) |
| "We examined 14 patients with progressive supranuclear palsy (PSP), another related neurodegenerative disorder characterized by severe widespread cholinergic deficits and known central hypersensitivity to cholinergic blockade, to determine whether they also showed a marked pupil dilation after administration of dilute tropicamide eye drops." | 1.29 | Can tropicamide eye drop response differentiate patients with progressive supranuclear palsy and Alzheimer's disease from healthy control subjects? ( FitzGibbon, EJ; Litvan, I, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 30 (83.33) | 18.2507 |
| 2000's | 5 (13.89) | 29.6817 |
| 2010's | 1 (2.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Heaton, GR | 1 |
| Davis, BM | 1 |
| Turner, LA | 1 |
| Cordeiro, MF | 1 |
| Grünberger, J | 2 |
| Prause, W | 1 |
| Frottier, P | 1 |
| Stöhr, H | 2 |
| Saletu, B | 1 |
| Haushofer, M | 1 |
| Rainer, M | 2 |
| Granholm, E | 1 |
| Morris, S | 1 |
| Galasko, D | 1 |
| Shults, C | 1 |
| Rogers, E | 1 |
| Vukov, B | 1 |
| Iijima, A | 1 |
| Haida, M | 1 |
| Ishikawa, N | 1 |
| Ueno, A | 1 |
| Minamitani, H | 1 |
| Shinohara, Y | 1 |
| Hou, RH | 1 |
| Samuels, ER | 1 |
| Raisi, M | 1 |
| Langley, RW | 1 |
| Szabadi, E | 1 |
| Bradshaw, CM | 1 |
| Scinto, LF | 3 |
| Wilhelm, H | 1 |
| Wilhelm, B | 1 |
| Zrenner, E | 1 |
| Berciano, J | 1 |
| Marx, JL | 1 |
| Kumar, SR | 1 |
| Thach, AB | 1 |
| Kiat-Winarko, T | 1 |
| Frambach, DA | 1 |
| Treloar, A | 1 |
| Assin, M | 2 |
| Macdonald, A | 1 |
| Daffner, KR | 2 |
| Dressler, D | 1 |
| Ransil, BI | 1 |
| Rentz, D | 1 |
| Weintraub, S | 1 |
| Mesulam, M | 1 |
| Potter, H | 2 |
| Barinaga, M | 1 |
| Loupe, DN | 1 |
| Newman, NJ | 2 |
| Green, RC | 1 |
| Lynn, MJ | 1 |
| WIlliams, KK | 1 |
| Geis, TC | 1 |
| Edelhauser, HF | 1 |
| Arai, H | 4 |
| Terajima, M | 1 |
| Nakagawa, T | 1 |
| Higuchi, S | 3 |
| Mochizuki, H | 1 |
| Sasaki, H | 1 |
| Fridh, M | 1 |
| Havelius, U | 1 |
| Elofsson, G | 1 |
| Hindfelt, B | 1 |
| Robles, A | 1 |
| Touriño, R | 1 |
| Sesar, A | 1 |
| Suárez, P | 1 |
| Noya, M | 1 |
| Treloar, AJ | 1 |
| Macdonald, AJ | 1 |
| Gómez-Tortosa, E | 1 |
| del Barrio, A | 1 |
| Jiménez-Alfaro, I | 1 |
| Litvan, I | 1 |
| FitzGibbon, EJ | 1 |
| Kono, K | 1 |
| Miyao, M | 1 |
| Ishihara, S | 1 |
| Takagi, A | 1 |
| Ikari, H | 1 |
| Suzuki, Y | 1 |
| Iguchi, A | 1 |
| FitzSimon, JS | 1 |
| Waring, SC | 1 |
| Kokmen, E | 1 |
| McLaren, JW | 1 |
| Brubaker, RF | 1 |
| Kurz, A | 1 |
| Marquard, R | 1 |
| Fremke, S | 1 |
| Leipert, KP | 1 |
| Reitner, A | 1 |
| Baumgartner, I | 1 |
| Thuile, C | 1 |
| Baradaran Dilmaghani, R | 1 |
| Ergun, E | 1 |
| Kaminski, S | 1 |
| Lukas, J | 1 |
| Dal Bianco, P | 1 |
| Kálmán, J | 1 |
| Kanka, A | 1 |
| Maglóczky, E | 1 |
| Szóke, A | 1 |
| Járdánházy, T | 1 |
| Janka, Z | 1 |
| Matsushita, S | 2 |
| Hasegawa, Y | 2 |
| Muramatsu, T | 2 |
| Hayashida, M | 1 |
| Graff-Radford, NR | 1 |
| Lin, SC | 1 |
| Brazis, PW | 1 |
| Bolling, JP | 1 |
| Liesegang, TJ | 1 |
| Lucas, JA | 1 |
| Uitti, RJ | 1 |
| O'Brien, PC | 1 |
| Growdon, JH | 1 |
| Graefe, K | 1 |
| Tennis, M | 1 |
| Hayden, D | 1 |
| Schoenfeld, D | 1 |
| Wray, SH | 1 |
| Kardon, RH | 1 |
| Ferrario, E | 1 |
| Molaschi, M | 1 |
| Villa, L | 1 |
| Varetto, O | 1 |
| Bogetto, C | 1 |
| Nuzzi, R | 1 |
| Kaneyuki, H | 1 |
| Mitsuno, S | 1 |
| Nishida, T | 1 |
| Yamada, M | 1 |
| Rentz, DM | 1 |
| Verghese, J | 1 |
| Linzmayer, L | 1 |
| Walter, H | 1 |
| Masching, A | 1 |
| Pezawas, L | 1 |
| Saletu-Zyhlarz, G | 1 |
| Grünberger, M | 1 |
3 reviews available for tropicamide and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Ocular biomarkers of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Choroid; Disease Models, Animal; Disease Progress | 2015 |
Biological markers for the clinical diagnosis of Alzheimer's disease.
Topics: Aged; Alleles; alpha 1-Antichymotrypsin; Alzheimer Disease; Amyloid beta-Peptides; Apolipoproteins E | 1996 |
Drop the Alzheimer's drop test.
Topics: Alzheimer Disease; Humans; Mydriatics; Pupil; Tropicamide | 1998 |
10 trials available for tropicamide and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Tropicamide effects on pupil size and pupillary light reflexes in Alzheimer's and Parkinson's disease.
Topics: Aged; Alzheimer Disease; Female; Humans; Light; Male; Muscarinic Antagonists; Ophthalmic Solutions; | 2003 |
Re-evaluation of tropicamide in the pupillary response test for Alzheimer's disease.
Topics: Adult; Aged; Alzheimer Disease; Dementia, Vascular; Diagnosis, Computer-Assisted; Diagnosis, Differe | 2003 |
A potential noninvasive neurobiological test for Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Dementia; Female; Humans; Male; Neuropsychological Tests; Pupil; Reproducib | 1994 |
Pupillary response to tropicamide in patients with Alzheimer disease.
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Female; Humans; Male; | 1996 |
Response of the pupil to tropicamide is not a reliable test for Alzheimer disease.
Topics: Aged; Alzheimer Disease; Female; Humans; Male; Mydriasis; Placebos; Pupil; Tropicamide | 1997 |
Pupil dilation response to tropicamide: a biological test for Alzheimer's disease?
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Humans; Middle Aged; Mydriatics; Psychiatric Status Rati | 1997 |
Increased mydriatic response to tropicamide is a sign of cholinergic hypersensitivity but not specific to late-onset sporadic type of Alzheimer's dementia.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinergic Antagonists; Dementia, Vascular; Female; Hum | 1997 |
Tropicamide eyedrops cannot be used for reliable diagnosis of Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Double-Blind Method; Female; Humans; Male; Middle Aged; | 1997 |
Pupil dilation to tropicamide is not specific for Alzheimer disease.
Topics: Aged; Alzheimer Disease; Diagnosis, Differential; Double-Blind Method; Female; Humans; Male; Middle | 1997 |
Is videopupillography useful in the diagnosis of Alzheimer's disease?
Topics: Aged; Alzheimer Disease; Female; Humans; Male; Muscarinic Antagonists; Pupil; Reference Values; Tele | 1998 |
23 other studies available for tropicamide and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
[The pupillary response test as a method to differentiate various types of dementia].
Topics: Aged; Alzheimer Disease; Dementia; Dementia, Vascular; Female; Humans; Lewy Body Disease; Male; Musc | 2009 |
Why patients with Alzheimer's disease may show increased sensitivity to tropicamide eye drops: role of locus coeruleus.
Topics: Adrenergic alpha-Agonists; Adult; Alzheimer Disease; Clonidine; Cross-Over Studies; Double-Blind Met | 2006 |
ApoE allelic variability influences pupil response to cholinergic challenge and cognitive impairment.
Topics: Administration, Topical; Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Apolipopr | 2007 |
[The Alzheimer test].
Topics: Aged; Alzheimer Disease; Humans; Mydriatics; Parasympathetic Nervous System; Predictive Value of Tes | 1995 |
[The pupil in Alzheimer's disease].
Topics: Aged; Alzheimer Disease; Brain; Humans; Hypersensitivity; Pupil; Tropicamide | 1995 |
Detecting Alzheimer's disease.
Topics: Adult; Aged; Alzheimer Disease; Female; Humans; Male; Pupil; Tropicamide | 1995 |
Detecting Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Dementia, Multi-Infarct; Diagnosis, Differential; Humans; Pupil; Tropicamid | 1995 |
Possible new test found for Alzheimer's disease.
Topics: Alzheimer Disease; Controlled Clinical Trials as Topic; Humans; Pupil; Tropicamide | 1994 |
Pupil dilatation assay by tropicamide is modulated by apolipoprotein E epsilon 4 allele dosage in Alzheimer's disease.
Topics: Aged; Alleles; Alzheimer Disease; Apolipoproteins E; Case-Control Studies; Gene Dosage; Genotype; Hu | 1996 |
The pupillary response to tropicamide in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Female; Humans; Male; Middle Aged; Mydriatics; Ophthalmi | 1996 |
[Experience with pupil tropicamide test in Alzheimer's disease].
Topics: Adult; Aged; Alzheimer Disease; Female; Humans; Male; Middle Aged; Mydriatics; Pupil; Tropicamide | 1996 |
Pupillary response to topical tropicamide as a marker for Alzheimer's disease.
Topics: Administration, Topical; Aged; Alzheimer Disease; Humans; Pupil; Tropicamide | 1996 |
Pupil response to tropicamide in Alzheimer's disease and other neurodegenerative disorders.
Topics: Aged; Alzheimer Disease; Female; Humans; Male; Middle Aged; Mydriatics; Pupil; Tropicamide | 1996 |
Can tropicamide eye drop response differentiate patients with progressive supranuclear palsy and Alzheimer's disease from healthy control subjects?
Topics: Aged; Alzheimer Disease; Female; Humans; Male; Ophthalmic Solutions; Supranuclear Palsy, Progressive | 1996 |
[Hypersensitivity in the pupil dilation response to a cholinergic antagonist in patients with Alzheimer's disease and Down's syndrome].
Topics: Adult; Aged; Alzheimer Disease; Down Syndrome; Drug Hypersensitivity; Female; Humans; Male; Matched- | 1996 |
The mydriatic effect of tropicamide and its diagnostic use in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Cornea; Female; Humans; Male; Mydriatics; Pupil; Reproducibility of Results | 1997 |
Pupillary response to tropicamide in Japanese patients with alcoholic dementia, Alzheimer's disease, and vascular dementia.
Topics: Aged; Aging; Alcoholism; Alzheimer Disease; Dementia; Dementia, Vascular; Humans; Middle Aged; Mydri | 1997 |
Apolipoprotein E epsilon 4 allele and pupillary response to tropicamide.
Topics: Aging; Alleles; Alzheimer Disease; Apolipoprotein E4; Apolipoproteins E; Female; Genotype; Humans; M | 1997 |
The eyes don't have it in Alzheimer's disease.
Topics: Alzheimer Disease; Humans; Mydriatics; Sensitivity and Specificity; Tropicamide | 1997 |
Enhanced miotic response to topical dilute pilocarpine in patients with Alzheimer's disease.
Topics: Administration, Topical; Aged; Alzheimer Disease; Female; Humans; Male; Miotics; Mydriatics; Pilocar | 1998 |
Pupil assay and Alzheimer's disease: a critical analysis.
Topics: Alzheimer Disease; Humans; Mydriatics; Pupil; Tropicamide | 1999 |
Is videopupillography useful in diagnosing Alzheimer's disease?
Topics: Alzheimer Disease; Humans; Muscarinic Antagonists; Pupil; Reference Values; Television; Tropicamide | 1999 |
Receptor test (pupillary dilatation after application of 0.01% tropicamide solution) and determination of central nervous activation (Fourier analysis of pupillary oscillations) in patients with Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Case-Control Studies; Central Nervous System; Female; Fourier Analysis; Hum | 1999 |