Page last updated: 2024-09-05

troleandomycin and Disease Models, Animal

troleandomycin has been researched along with Disease Models, Animal in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davis, CD; Dworetzky, S; Fitzpatrick, WC; Harden, D; He, H; Knox, RJ; Newton, AE; Philip, T; Polson, C; Sinz, MW; Sivarao, DV; Sun, LQ; Tertyshnikova, S; Weaver, D; Wu, YJ; Yeola, S; Zoeckler, M1
Allard, JL; Court, MH; Duan, SX; Gonzalez, FJ; Gorman, N; Greenblatt, DJ; Hao, Q; Hunt, JA; Jeffery, EH; Kostrubsky, V; Sinclair, JF; Sinclair, PR; Szakacs, JG; von Moltke, LL; Walton-Strong, BW; Wolf, KK; Wood, SG; Wrighton, SA1
Brain, EG; Drewes, P; Gustafsson, K; Hecht, JE; Waxman, DJ; Yu, LJ1
Fraser, T; Li, M; Wen, C; Whitworth, JA1
Franklin, MR; Kushner, JP; Phillips, JD1

Other Studies

5 other study(ies) available for troleandomycin and Disease Models, Animal

ArticleYear
Fluorine substitution can block CYP3A4 metabolism-dependent inhibition: identification of (S)-N-[1-(4-fluoro-3- morpholin-4-ylphenyl)ethyl]-3- (4-fluorophenyl)acrylamide as an orally bioavailable KCNQ2 opener devoid of CYP3A4 metabolism-dependent inhibiti
    Journal of medicinal chemistry, 2003, Aug-28, Volume: 46, Issue:18

    Topics: Administration, Oral; Animals; Biological Availability; Cell Line; Cinnamates; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Disease Models, Animal; Fluorine; Injections, Intravenous; Ion Channel Gating; KCNQ2 Potassium Channel; Male; Membrane Potentials; Migraine Disorders; Morpholines; Parietal Lobe; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Voltage-Gated; Rats; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship

2003
Role of CYP3A and CYP2E1 in alcohol-mediated increases in acetaminophen hepatotoxicity: comparison of wild-type and Cyp2e1(-/-) mice.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:7

    Topics: Acetaminophen; Alanine Transaminase; Animals; Benzoquinones; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Disease Models, Animal; Drug Synergism; Enzyme Induction; Enzyme Inhibitors; Ethanol; Glucuronides; Glutathione; Hydroxylation; Imines; Liver; Liver Diseases; Male; Mice; Mice, Knockout; Pentanols; Severity of Illness Index; Testosterone; Troleandomycin

2007
In vivo modulation of alternative pathways of P-450-catalyzed cyclophosphamide metabolism: impact on pharmacokinetics and antitumor activity.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 288, Issue:3

    Topics: Animals; Antineoplastic Agents; Area Under Curve; Brain Neoplasms; Cyclophosphamide; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Disease Models, Animal; Enzyme Induction; Female; Gliosarcoma; Half-Life; Hydroxylation; Ifosfamide; Liver; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred F344; Troleandomycin

1999
Adrenocorticotrophin-induced hypertension: effects of mineralocorticoid and glucocorticoid receptor antagonism.
    Journal of hypertension, 1999, Volume: 17, Issue:3

    Topics: Adrenocorticotropic Hormone; Animals; Anti-Bacterial Agents; Blood Pressure; Disease Models, Animal; Drug Therapy, Combination; Hypertension; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Potassium; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Sodium; Spironolactone; Troleandomycin

1999
CYP3A-inducing agents and the attenuation of uroporphyrin accumulation and excretion in a rat model of porphyria cutanea tarda.
    Biochemical pharmacology, 2000, Nov-01, Volume: 60, Issue:9

    Topics: Animals; Anti-Bacterial Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Disease Models, Animal; Enzyme Induction; Female; Oxidoreductases, N-Demethylating; Porphyria Cutanea Tarda; Pregnenolone Carbonitrile; Rats; Rats, Inbred F344; Troleandomycin; Uroporphyrins

2000