trolamine salicylate has been researched along with Allodynia in 92 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (14.13) | 18.2507 |
| 2000's | 29 (31.52) | 29.6817 |
| 2010's | 41 (44.57) | 24.3611 |
| 2020's | 9 (9.78) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, SJ; Luo, JG; Ren, F; Yan, JQ; Zhou, LY; Zou, WY | 1 |
| Chen, H; Jiang, H; Liu, Q; Nie, B | 1 |
| Coutinho, HDM; de Albuquerque Junior, RLC; de Souza Araújo, AA; de Souza Siqueira Lima, P; de Souza Siqueira Quintans, J; Heimfarth, L; Kim, B; Lima, NT; Monteiro, BS; Passos, FRS; Pereira, EWM; Quintans Júnior, LJ; Rezende, MM; Santos, TKB; Souza, ICL | 1 |
| Ahmad, S; Din, FU; Khan, A; Khan, AU; Khan, S; Li, CH; Rehman, ZU; Shal, B; Wang, F; Zhang, L | 1 |
| Chai, XQ; Gao, W; Hu, SS; Long, DD; Pan, TT; Shen, L; Wang, D | 1 |
| Alves, MS; Amaral, FA; Barbosa, BCM; Braga, AD; Braga, AV; Carneiro, FS; Carvalho, AFS; Coelho, MM; Costa, SOAM; da Costa, YFG; Lino, CI; Machado, RR; Melo, ISF; Morais, MI; Moreira, NF; Oliveira, RB; Oliveira, VLS; Queiroz-Junior, CM; Rodrigues, FF; Sousa, LP; Zaidan, I | 1 |
| Ble-González, EA; González-Cortazar, M; Herrera-Ruiz, M; Jiménez-Aparicio, AR; Jiménez-Ferrer, E; Montiel-Ruiz, RM; Vargas-Ruiz, R; Zamilpa, A | 1 |
| Lucena, F; McDougall, JJ | 1 |
| Fitzgerald, M; La Hausse De Lalouviere, L; Morice, O | 1 |
| Castro-Lopes, JM; Ferreira, AC; Malcangio, M; Nascimento, DSM; Neto, FLM; Potes, CS; Soares, ML | 1 |
| Cañizares, FJ; Cobos, EJ; Entrena, JM; Fernández-Segura, E; Montilla-García, Á; Perazzoli, G; Portillo-Salido, E; Tejada, MÁ | 1 |
| Cavalcante, ALC; de Araújo, JCB; de Castro Brito, GA; Gondim, DV; Lisboa, MRP; Vale, ML | 1 |
| Deng, XM; Guo, QH; Hu, ML; Li, H; Li, HL; Xu, H; Zhang, YQ; Zhou, SZ; Zhou, YL | 1 |
| Almahasneh, F; Ashby, WR; Ballmer-Hofer, K; Bates, DO; Beazley-Long, N; Benest, AV; Bestall, SM; Blackley, Z; Donaldson, LF; Durrant, AM; Hirashima, M; Hodge, D; Hulse, RP | 1 |
| Agalave, NM; Denk, F; Estelius, J; Fernandez-Zafra, T; Gao, T; Hokfelt, T; Hore, Z; Jurczak, A; Lampa, J; Sandor, K; Su, J; Svensson, CI; Wiesenfeld-Hallin, Z; Xu, X | 1 |
| Bui, A; Corr, M; Fujita, Y; Gonçalves Dos Santos, G; Ocheltree, C; Woller, SA; Wong, SY; Yaksh, TL | 1 |
| Gunjegaonkar, SM; Shanmugarajan, TS | 1 |
| Kaewnopparat, N; Mo, J; Nitiruangjaras, A; Panichayupakaranant, P; Reanmongkol, W | 1 |
| Longo, G; Osikowicz, M; Ribeiro-da-Silva, A | 1 |
| Hong, Y; Wang, D; Zhou, X | 1 |
| Almeida, A; Amorim, D; Costa, P; David-Pereira, A; Monteiro, AM; Pertovaara, A; Pinto-Ribeiro, F | 1 |
| Almeida, A; Amorim, D; David-Pereira, A; Pertovaara, A; Pinto-Ribeiro, F | 1 |
| Grégoire, S; Ji, G; Medina, G; Neugebauer, V | 1 |
| Ebbinghaus, M; Gajda, M; Holtzman, MJ; Schaible, HG; Schulz, S | 1 |
| Carr, FB; Géranton, SM; Hunt, SP | 1 |
| Almeida, A; Amorim, D; Costa, P; David-Pereira, A; Marques, P; Pertovaara, A; Pinto-Ribeiro, F; Puga, S; Rebelo, P | 1 |
| Schaible, HG | 1 |
| Gao, T; Hökfelt, T; Shi, T; Su, J; Svensson, CI; Wiesenfeld-Hallin, Z; Xiang, Q; Xu, X | 1 |
| Figueiredo, MJ; Kanashiro, A; Malvar, Ddo C; Souza, GE | 1 |
| Camargo, LL; Costa, SK; Denadai-Souza, A; Fernandes, E; Grant, A; Lima, C; Mesquita, FP; Muscará, MN; Schenka, A; Soares, AG; Yshii, LM | 1 |
| Al-Kaysi, A; Barnett, E; Brown, CA; El-Deredy, W; Fairclough, M; Jones, AKP; Matthews, J; McMahon, A | 1 |
| Corr, M; McQueen, J; Park, HJ; Sandor, K; Svensson, CI; Woller, SA; Yaksh, TL | 1 |
| Almeida, A; Amorim, D; David-Pereira, A; Gonçalves, S; Pertovaara, A; Pinto-Ribeiro, F; Puga, S; Silva, C | 1 |
| Almeida, A; Amorim, D; Pertovaara, A; Pinto-Ribeiro, F; Viisanen, H; Wei, H | 1 |
| Domínguez-Ramírez, AM; Espinosa-Juárez, JV; García-Martínez, BA; Jaramillo-Morales, OA; López-Muñoz, FJ; Medina-López, JR; Melo-Hernández, LA; Navarrete-Vázquez, G; Schepmann, D; Wünsch, B | 1 |
| Hamaue, Y; Honda, Y; Kataoka, H; Kondo, Y; Nakabayashi, K; Nakano, J; Okita, M; Sakamoto, J | 1 |
| Borbély, É; Helyes, Z; Kemény, Á; Markovics, A; McDougall, JJ; Pintér, E; Quinn, JP; Sándor, K; Szolcsányi, J | 1 |
| Almahasneh, F; Donaldson, LF; Drake, RA; Leith, JL; Lumb, B; Martindale, J; Wilson, AW | 1 |
| Bonacorso, HG; Brum, ES; Brusco, I; Frizzo, CP; Oliveira, SM; Rodrigues, MB; Rosa, WC; Zanatta, N | 1 |
| Boettger, MK; Ebersberger, A; Natura, G; Richter, F; Schaible, HG; Segond von Banchet, G; Vanegas, H; Vazquez, E | 1 |
| Borbély, E; Elekes, K; Helyes, Z; McDougall, JJ; Pintér, E; Sándor, K; Szolcsányi, J; Tékus, V; Tóth, DM | 1 |
| Boros, M; Eros, G; Ghyczy, M; Gurabi, D; Hartmann, P; Horváth, G; Németh, I; Szabó, A | 1 |
| Cunha, FQ; Cunha, TM; Ferreira, SH; Lemos, HP; Pinto, LG; Verri, WA; Vieira, SM | 1 |
| Boettger, MK; Bräuer, R; Brenn, D; Gajda, M; Hensellek, S; Natura, G; Richter, F; Schaible, HG; von Banchet, GS | 1 |
| Abu-Ghefreh, AA; Masocha, W | 1 |
| Berthelette, C; Boyd, MJ; Chiasson, JF; Clark, P; Colucci, J; Denis, D; Han, Y; Lévesque, JF; Mathieu, MC; Rowland, S; Stocco, R; Therien, A; Wrona, M; Xu, D | 1 |
| Chaudhary, P; Kumar, VL; Matos, MP; Mohan, M; Ramos, MV | 1 |
| Almarestani, L; Bennett, GJ; Fitzcharles, MA; Ribeiro-da-Silva, A | 1 |
| Aono, H; Hata, T; Narita, M; Niwa, M; Sasano, M; Suzuki, T; Tsuji, F; Tsukahara-Ohsumi, Y | 1 |
| Deng, XM; Li, SS; Xu, B; Xu, H; Yang, JL; Zhang, WS; Zhang, YQ | 1 |
| Bloem, JL; Huizinga, TW; Krabben, A; Reijnierse, M; Stomp, W; van der Heijde, DM; van der Helm-van Mil, AH; van Nies, JA | 1 |
| Caro, M; de Lecea, L; Delgado, M; Forte-Lago, I; Gonzalez-Rey, E; Morell, M; O'Valle, F; Souza-Moreira, L | 1 |
| Ebersberger, A; Schaible, HG; Von Banchet, GS | 1 |
| Beaudet, A; Cahill, CM; Hoffert, C; Morinville, A; O'Donnell, D | 1 |
| Iwai, A; Kiso, T; Kohara, A; Nagakura, Y; Okada, M; Toya, T; Wanibuchi, F; Yamaguchi, T | 1 |
| Arévalo, MI; Calpena, A; Domenech, J; Escribano, E; Queralt, J | 1 |
| Amagasa, T; Fujiyama, R; Takeuchi, Y; Toda, K; Zeredo, JL | 1 |
| Castro, AR; Lima, D; Pinto, M; Tavares, I | 2 |
| Krause, E; Selve, N; Stöhr, T | 1 |
| Chernajovsky, Y; Hunt, SP; Inglis, JJ; Kidd, BL; Lees, DM; Nissim, A | 1 |
| Chen, WL; Sun, S; Wang, PF; Zhang, YQ; Zhao, ZQ | 1 |
| Chillingworth, NL; Donaldson, LF; Morham, SG | 1 |
| Green, PG; Khasar, SG; Levine, JD | 1 |
| Leeper, BJ; Radhakrishnan, R; Skyba, DA; Sluka, KA; Wright, A | 1 |
| Cao, H; Han, M; Li, TT; Pan, HL; Sun, S; Zhang, YQ; Zhao, ZQ | 1 |
| Costa, B | 1 |
| Barton, NJ; Bate, ST; Bond, SM; Brash, HM; Chessell, IP; McQueen, DS; Reeve, AJ; Strickland, IT; Wilson, AW | 1 |
| Matsumoto, S; Nasu, M; Takeda, M; Tanimoto, T | 1 |
| Bouhassira, D; Chauvin, M; Fletcher, D; Martinez, V; Sessler, DI | 1 |
| Anand, P; Essex, D; Feldmann, M; Inglis, JJ; Notley, CA; Williams, R; Wilson, AW | 1 |
| Burnes, LA; Ikeuchi, M; Kolker, SJ; Sluka, KA; Walder, RY | 1 |
| Desantana, JM; Santana-Filho, VJ; Sluka, KA | 1 |
| Davis, AJ; Kelly, D; Perkins, MN | 1 |
| Sluka, KA; Westlund, KN; Willis, WD | 2 |
| Okuda-Akabane, K | 1 |
| Neugebauer, V; Rumenapp, P; Schaible, HG | 1 |
| Cervero, F; Herrero, JF | 1 |
| Houghton, AK; Westlund, KN | 1 |
| Milton, MA; Sluka, KA; Westlund, KN; Willis, WD | 1 |
| Lawand, NB; Westlund, KN; Willis, WD | 1 |
| Ferreira, SH; Tonussi, CR | 1 |
| Castro, MS; Francischi, JN; Pereira, LS | 1 |
| Houghton, AK; Lu, Y; Westlund, KN | 1 |
| Sluka, KA | 1 |
| Ebersberger, A; Malcangio, M; Mazario, J; Meyer-Tuve, A; Schaible, HG | 1 |
| Beitz, AJ; Han, HJ; Kang, SK; Kwon, YB; Lee, HJ; Lee, JD; Lee, JH; Mar, WC | 1 |
| Sluka, KA; Wright, A | 1 |
| Beaufour, C; Braz, J; Cesselin, F; Coutaux, A; Epstein, AL; Hamon, M; Pohl, M | 1 |
| Fuseler, J; Grisham, M; Roerig, SC; Tedesco, LS; Wolf, R | 1 |
| Kopp, S | 1 |
6 review(s) available for trolamine salicylate and Allodynia
| Article | Year |
|---|---|
Nociceptive neurons detect cytokines in arthritis.
Topics: Analgesics; Animals; Arthritis; Cytokines; Humans; Hyperalgesia; Models, Biological; Nociceptors; Pain; Sensory Receptor Cells | 2014 |
Joint pain.
Topics: Animals; Arthralgia; Arthritis; Brain; Cytokines; Excitatory Amino Acids; Humans; Hyperalgesia; Joints; Neuropeptides; Nociceptors; Pain; Physical Stimulation; Prostaglandins; Spinal Cord | 2009 |
The role of proinflammatory cytokines in the generation and maintenance of joint pain.
Topics: Animals; Arthralgia; Arthritis; Arthritis, Experimental; Cells, Cultured; Cytokines; Disease Models, Animal; Ganglia, Spinal; Hyperalgesia; Interleukin-6; Knee Joint; Neurons, Afferent; Rats; TRPV Cation Channels; Tumor Necrosis Factor-alpha | 2010 |
Mechanisms of pain in arthritis.
Topics: Afferent Pathways; Analgesics, Non-Narcotic; Animals; Arthritis; Cyclooxygenase Inhibitors; Dinoprostone; Efferent Pathways; Ganglia, Spinal; Glutamic Acid; Humans; Hyperalgesia; Inflammation Mediators; Ion Channel Gating; Mechanoreceptors; Models, Biological; Neuropeptides; Nociceptors; Pain; Rats; Receptors, Neuropeptide; Receptors, Neurotransmitter; Receptors, Prostaglandin E; Spinal Cord | 2002 |
Neurogenic inflammation and arthritis.
Topics: Adrenal Medulla; Animals; Arthritis; Humans; Hyperalgesia; Neurogenic Inflammation; Pain; Sex Characteristics | 2006 |
Neuroendocrine, immune, and local responses related to temporomandibular disorders.
Topics: Arthritis; Calcitonin Gene-Related Peptide; Dinoprostone; Facial Pain; Fibromyalgia; Humans; Hyperalgesia; Inflammation Mediators; Interleukin-1; Leukotriene B4; Masseter Muscle; Neuroimmunomodulation; Neuropeptide Y; Neuropeptides; Neurosecretory Systems; Open Bite; Serotonin; Substance P; Synovial Fluid; Temporomandibular Joint Disorders; Tumor Necrosis Factor-alpha | 2001 |
86 other study(ies) available for trolamine salicylate and Allodynia
| Article | Year |
|---|---|
Inhibition of Spinal Interleukin-33 Attenuates Peripheral Inflammation and Hyperalgesia in Experimental Arthritis.
Topics: Animals; Arthritis; Cytokines; Extracellular Signal-Regulated MAP Kinases; Freund's Adjuvant; Hyperalgesia; Inflammation; Interleukin-33; NF-kappa B; Rats; Spinal Cord | 2022 |
Dexmedetomidine alleviates hyperalgesia in arthritis rats through inhibition of the p38MAPK signaling pathway.
Topics: Animals; Anisomycin; Arthritis; Dexmedetomidine; Freund's Adjuvant; Hyperalgesia; Inflammation; MAP Kinase Signaling System; Rats; Rats, Sprague-Dawley | 2022 |
Pharmacological effects of a complex α-bisabolol/β-cyclodextrin in a mice arthritis model with involvement of IL-1β, IL-6 and MAPK.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; beta-Cyclodextrins; Chronic Pain; Disease Models, Animal; Edema; Hyperalgesia; Interleukin-1beta; Interleukin-6; Male; Mice; Monocyclic Sesquiterpenes | 2022 |
Suppression of NF-κB signaling by ECN in an arthritic model of inflammation.
Topics: Animals; Arthritis; Carrageenan; Cyclooxygenase 2; Edema; Freund's Adjuvant; Hyperalgesia; Inflammation; Mice; Molecular Docking Simulation; NF-kappa B; Tumor Necrosis Factor-alpha | 2022 |
Angiotensin II type 2 receptor pharmacological agonist, C21, reduces the inflammation and pain hypersensitivity in mice with joint inflammatory pain.
Topics: Animals; Arthritis; Hyperalgesia; Imidazoles; Inflammation; Mice; Microglia; Pain; Receptor, Angiotensin, Type 2; Spinal Cord; Sulfonamides; Thiophenes | 2022 |
A clindamycin acetylated derivative with reduced antibacterial activity inhibits articular hyperalgesia and edema by attenuating neutrophil recruitment, NF-κB activation and tumor necrosis factor-α production.
Topics: Animals; Anti-Bacterial Agents; Arthritis; Clindamycin; Edema; Hyperalgesia; Inflammation; Lipopolysaccharides; Mice; Neutrophil Infiltration; NF-kappa B; Tumor Necrosis Factor-alpha; Zymosan | 2023 |
Effect of phenolic compounds from Oenothera rosea on the kaolin-carrageenan induced arthritis model in mice.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Carrageenan; Cell Line; Cytokines; Disease Models, Animal; Female; Hyperalgesia; Kaolin; Mice, Inbred ICR; NF-kappa B; Oenothera; Phenols; Phytochemicals; Plant Components, Aerial; Plant Extracts; Synovial Membrane | 2020 |
Pain responses to protease-activated receptor-2 stimulation in the spinal cord of naïve and arthritic rats.
Topics: Animals; Arthritis; Dipeptides; Disease Models, Animal; Hyperalgesia; Isoxazoles; Male; Nociception; Pain Threshold; Rats, Wistar; Receptor, PAR-2; Spinal Cord | 2020 |
Altered sensory innervation and pain hypersensitivity in a model of young painful arthritic joints: short- and long-term effects.
Topics: Aging; Animals; Ankle Joint; Arthritis; Calcitonin Gene-Related Peptide; Disease Models, Animal; Freund's Adjuvant; Hyperalgesia; Injections, Intra-Articular; Male; Nerve Fibers; Neurofilament Proteins; Pain; Pain Measurement; Rats, Sprague-Dawley; Touch | 2021 |
Drug-Induced HSP90 Inhibition Alleviates Pain in Monoarthritic Rats and Alters the Expression of New Putative Pain Players at the DRG.
Topics: Activating Transcription Factor 3; Animals; Arthritis; Benzoquinones; Cells, Cultured; Ganglia, Spinal; Gene Expression Regulation; Gene Knockdown Techniques; Glial Fibrillary Acidic Protein; HSP90 Heat-Shock Proteins; Hyperalgesia; Lactams, Macrocyclic; Male; Models, Biological; Pain; Rats, Wistar; Receptors, Purinergic P2X3; Receptors, Purinergic P2X7; Up-Regulation | 2018 |
Grip strength in mice with joint inflammation: A rheumatology function test sensitive to pain and analgesia.
Topics: Acetaminophen; Analgesics; Animals; Arthritis; Celecoxib; Disease Models, Animal; Diterpenes; Female; Freund's Adjuvant; Hand Strength; Hyperalgesia; Ibuprofen; Inflammation; Muscle Strength; Nociceptors; Oxycodone; Pain Measurement; Rheumatic Diseases; Ruthenium Red; Tarsus, Animal; Touch; Tramadol; TRPV Cation Channels | 2017 |
Inflammatory pain assessment in the arthritis of the temporomandibular joint in rats: A comparison between two phlogistic agents.
Topics: Animals; Arthritis; Carrageenan; Disease Models, Animal; Hyperalgesia; Injections, Intra-Articular; Macrophages; Male; Microglia; Nociception; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Rats, Wistar; Temporomandibular Joint Disorders; Trigeminal Ganglion; Zymosan | 2017 |
Bidirectional modulation between infiltrating CD3
Topics: Animals; Arthritis; Astrocytes; Disease Models, Animal; Glial Fibrillary Acidic Protein; Homeodomain Proteins; Hyperalgesia; Interferon-gamma; Lymphocyte Activation; Neuroglia; NF-kappa B; Phosphorylation; Rats; Spinal Cord; Spinal Cord Dorsal Horn; T-Lymphocytes | 2018 |
VEGFR2 promotes central endothelial activation and the spread of pain in inflammatory arthritis.
Topics: Animals; Arthritis; Astrocytes; Chronic Pain; Endothelial Cells; Endothelium; Hyperalgesia; Inflammation; Male; Mice; Mice, Transgenic; Microglia; Neuralgia; Pain; Pilot Projects; Rats; Rats, Wistar; Spinal Cord; Spinal Cord Dorsal Horn; Vascular Endothelial Growth Factor Receptor-2 | 2018 |
Exploring the transcriptome of resident spinal microglia after collagen antibody-induced arthritis.
Topics: Animals; Antibodies; Antigens, CD; Arthritis; Collagen; Disease Models, Animal; Female; Hyperalgesia; Male; Mice, Inbred C57BL; Microglia; Nerve Tissue Proteins; RNA, Messenger; Spinal Cord; Time Factors; Transcriptome | 2019 |
Neuraxial TNF and IFN-beta co-modulate persistent allodynia in arthritic mice.
Topics: Animals; Arthritis; Arthritis, Rheumatoid; Central Nervous System; Disease Models, Animal; Female; Hyperalgesia; Interferon-beta; Male; Mice; Mice, Inbred C57BL; Pain; Sex Factors; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2019 |
Methyl jasmonate a stress phytohormone attenuates LPS induced in vivo and in vitro arthritis.
Topics: Acetates; Animals; Arthritis; Behavior, Animal; Chondrocytes; Cold Temperature; Cyclooxygenase 2; Cyclopentanes; Dinoprostone; Hyperalgesia; Interleukin-2; Lipopolysaccharides; Male; Matrix Metalloproteinases; Nitric Oxide; Oxylipins; Pancreatic Elastase; Peptide Hydrolases; Peroxidase; Plant Growth Regulators; Rats, Wistar; Stress, Physiological; Tail; Tumor Necrosis Factor-alpha | 2019 |
Topical anti-inflammatory and analgesic activities of standardized pomegranate rind extract in comparison with its marker compound ellagic acid in vivo.
Topics: Administration, Topical; Analgesics; Animals; Ankle Joint; Anti-Inflammatory Agents; Arthritis; Carrageenan; Croton Oil; Ear; Edema; Ellagic Acid; Foot; Formaldehyde; Freund's Adjuvant; Hyperalgesia; Lythraceae; Male; Mice; Mice, Inbred ICR; Pain; Phytotherapy; Plant Extracts; Rats; Rats, Wistar | 2013 |
Sympathetic fiber sprouting in inflamed joints and adjacent skin contributes to pain-related behavior in arthritis.
Topics: Adrenergic Fibers; Analysis of Variance; Animals; Ankle Joint; Arthritis; Calcitonin Gene-Related Peptide; Dermis; Disease Models, Animal; Freund's Adjuvant; Gene Expression Regulation; Guanethidine; Hyperalgesia; Male; Nerve Growth Factor; Nerve Growth Factors; Pain; Pain Measurement; Pain Threshold; Protein Precursors; Rats; Rats, Sprague-Dawley; Sympatholytics; Time Factors; Vesicular Monoamine Transport Proteins | 2013 |
Effects of a combination of ketanserin and propranolol on inflammatory hyperalgesia in rats.
Topics: Analgesics; Animals; Arthritis; Carrageenan; Dose-Response Relationship, Drug; Drug Interactions; Hyperalgesia; Inflammation; Ketanserin; Male; Myalgia; Piperazines; Propranolol; Pyridines; Rats; Rats, Sprague-Dawley | 2013 |
Pronociception from the dorsomedial nucleus of the hypothalamus is mediated by the rostral ventromedial medulla in healthy controls but is absent in arthritic animals.
Topics: Animals; Arthritis; Bicuculline; Carrageenan; Disease Models, Animal; Dorsomedial Hypothalamic Nucleus; Drug Interactions; GABA-A Receptor Antagonists; Hyperalgesia; Male; Medulla Oblongata; Neural Pathways; Nociceptors; Pain Measurement; Pain Threshold; Physical Stimulation; Rats; Rats, Wistar; Reaction Time | 2013 |
Amitriptyline reverses hyperalgesia and improves associated mood-like disorders in a model of experimental monoarthritis.
Topics: Amitriptyline; Analgesics, Non-Narcotic; Animals; Arthritis; Carrageenan; Disease Models, Animal; Exploratory Behavior; Food Preferences; Hyperalgesia; Kaolin; Male; Maze Learning; Mood Disorders; Motor Activity; Pain Threshold; Physical Stimulation; Rats; Rats, Wistar; Swimming | 2014 |
Nasal application of neuropeptide S inhibits arthritis pain-related behaviors through an action in the amygdala.
Topics: Administration, Intranasal; Amygdala; Analgesics; Animals; Arthritis; Carrageenan; Disease Models, Animal; Hyperalgesia; Kaolin; Knee Joint; Male; Maze Learning; Neurons; Neuropeptides; Pain; Rats; Rats, Sprague-Dawley; Reflex; Spinal Cord; Vocalization, Animal | 2014 |
Does chloride channel accessory 3 have a role in arthritis pain? A study on murine antigen-induced arthritis.
Topics: Animals; Arthritis; Chloride Channels; Freund's Adjuvant; Ganglia, Spinal; Hot Temperature; Hyperalgesia; Mice, Knockout; Mucoproteins; Neurons; Niflumic Acid; Pain; Pain Perception | 2014 |
Descending controls modulate inflammatory joint pain and regulate CXC chemokine and iNOS expression in the dorsal horn.
Topics: 5,7-Dihydroxytryptamine; Animals; Arthritis; Chemokines, CXC; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; Hyperalgesia; Male; Medulla Oblongata; Neural Pathways; Nitric Oxide Synthase Type II; Opioid Peptides; Pain; Pain Threshold; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Ribosome Inactivating Proteins, Type 1; Saporins; Serotonin Agents; Spinal Cord | 2014 |
A role of supraspinal galanin in behavioural hyperalgesia in the rat.
Topics: Analysis of Variance; Animals; Arthritis; Carrageenan; Evoked Potentials, Somatosensory; Galanin; Hyperalgesia; Hypothalamus; Kaolin; Male; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Reaction Time; Signal Transduction | 2014 |
Phenotypic changes in dorsal root ganglion and spinal cord in the collagen antibody-induced arthritis mouse model.
Topics: Activating Transcription Factor 3; Animals; Antibodies; Arthritis; Calcium Channels; Collagen; Disease Models, Animal; Galanin; Ganglia, Spinal; Hyperalgesia; Lectins; Lipopolysaccharides; Male; Mice; Mice, Inbred CBA; Nerve Tissue Proteins; Neuropeptide Y; Spinal Cord; Substance P; Time Factors | 2015 |
Cytokines, but not corticotropin-releasing factor and endothelin-1, participate centrally in the febrile response in zymosan-induced arthritis in rats.
Topics: Animals; Arthritis; Body Temperature; Corticotropin-Releasing Hormone; Cytokines; Disease Models, Animal; Endothelin-1; Fever; Hyperalgesia; Male; Rats, Wistar; Zymosan | 2015 |
Peripheral neurokinin-1 receptors contribute to kaolin-induced acute monoarthritis in rats.
Topics: Animals; Animals, Newborn; Antidiarrheals; Arthritis; Capsaicin; Cytokines; Disease Models, Animal; Edema; Enzyme Inhibitors; Hyperalgesia; Indomethacin; Kaolin; Knee Joint; Male; Pain Measurement; Peroxidase; Piperidines; Quinuclidines; Rats; Rats, Wistar; Receptors, Neurokinin-1; Synovial Fluid | 2015 |
Striatal opioid receptor availability is related to acute and chronic pain perception in arthritis: does opioid adaptation increase resilience to chronic pain?
Topics: Adult; Aged; Arthritis; Carbon Radioisotopes; Chronic Pain; Corpus Striatum; Diprenorphine; Female; Humans; Hyperalgesia; Magnetic Resonance Imaging; Male; Middle Aged; Narcotic Antagonists; Oxygen Radioisotopes; Pain Perception; Pain Threshold; Periaqueductal Gray; Positron-Emission Tomography; Receptors, Opioid; Surveys and Questionnaires | 2015 |
The effect of gabapentin and ketorolac on allodynia and conditioned place preference in antibody-induced inflammation.
Topics: Amines; Analgesics; Animals; Arthritis; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Glucose-6-Phosphate Isomerase; Hyperalgesia; Ketorolac; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL | 2016 |
Metabotropic glutamate 5 receptor in the infralimbic cortex contributes to descending pain facilitation in healthy and arthritic animals.
Topics: Animals; Arthritis; Disease Models, Animal; Glutamic Acid; Hyperalgesia; Male; Nociception; Prefrontal Cortex; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5 | 2016 |
Galanin-Mediated Behavioural Hyperalgesia from the Dorsomedial Nucleus of the Hypothalamus Involves Two Independent Descending Pronociceptive Pathways.
Topics: Animals; Arthritis; Behavior, Animal; Disease Models, Animal; Electrophysiology; Galanin; Glutamic Acid; Hyperalgesia; Hypothalamus; Lidocaine; Male; Mediodorsal Thalamic Nucleus; Neurons; Nociception; Ondansetron; Pain; Pressure; Protein Precursors; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT3; Serotonin; Spinal Cord | 2015 |
Antinociceptive effects of a new sigma-1 receptor antagonist (N-(2-morpholin-4-yl-ethyl)-2-(1-naphthyloxy)acetamide) in two types of nociception.
Topics: Acetamides; Acetone; Analgesics; Analgesics, Opioid; Animals; Arthritis; Constriction, Pathologic; Dose-Response Relationship, Drug; Hyperalgesia; Male; Morphine; Naphthalenes; Neuralgia; Nociception; Pain; Piperazines; Rats; Rats, Wistar; Receptors, sigma; Sigma-1 Receptor | 2016 |
Effect of continuous passive motion initiated after the onset of arthritis on inflammation and secondary hyperalgesia in rats.
Topics: Animals; Arthritis; Calcitonin Gene-Related Peptide; Hyperalgesia; Inflammation; Male; Motion Therapy, Continuous Passive; Pain; Pain Threshold; Random Allocation; Range of Motion, Articular; Rats, Wistar; Restraint, Physical; Spinal Cord Dorsal Horn | 2016 |
Role of capsaicin-sensitive nerves and tachykinins in mast cell tryptase-induced inflammation of murine knees.
Topics: Animals; Arthritis; Calcitonin Gene-Related Peptide; Capsaicin; Cytokines; Edema; Hyperalgesia; Knee Joint; Male; Mice, Inbred C57BL; Mice, Knockout; Neurogenic Inflammation; Pain; Protein Precursors; Receptor, PAR-2; Receptors, Neurokinin-1; Substance P; Tachykinins; Touch; TRPV Cation Channels; Tryptases | 2016 |
Periaqueductal Grey EP3 Receptors Facilitate Spinal Nociception in Arthritic Secondary Hypersensitivity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Arthritis; Disease Models, Animal; Freund's Adjuvant; Hyperalgesia; Ketoprofen; Male; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Neurons; Nitriles; Nociception; Pain Measurement; Pain Threshold; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, Prostaglandin E, EP3 Subtype; RNA, Messenger; Spinal Cord; Statistics, Nonparametric; Sulfonamides; Time Factors | 2016 |
Synthesis of novel trifluoromethyl-substituted spiro-[chromeno[4,3-d]pyrimidine-5,1'-cycloalkanes], and evaluation of their analgesic effects in a mouse pain model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Benzopyrans; Capsaicin; Heterocyclic Compounds, 3-Ring; Hyperalgesia; Ketoprofen; Mice; Nociception; Pain; Pyrimidines; Spiro Compounds | 2017 |
Involvement of transient receptor potential vanilloid 1 receptors in protease-activated receptor-2-induced joint inflammation and nociception.
Topics: Anilides; Animals; Arthritis; Body Weight; Cinnamates; Cytokines; Enzyme Activation; Foot; Hindlimb; Hyperalgesia; Injections, Intra-Articular; Male; Mechanoreceptors; Mice; Mice, Inbred C57BL; Oligopeptides; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Receptor, PAR-2; TRPV Cation Channels | 2010 |
Anti-inflammatory effects of phosphatidylcholine in neutrophil leukocyte-dependent acute arthritis in rats.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Diclofenac; Hyperalgesia; Knee Joint; Male; Microcirculation; Neutrophils; Phosphatidylcholines; Rats; Rats, Wistar; Synovial Membrane | 2009 |
IL-17 mediates articular hypernociception in antigen-induced arthritis in mice.
Topics: Analysis of Variance; Animals; Antibodies, Monoclonal; Antigens; Antirheumatic Agents; Arthritis; Cell Movement; Cytokines; Dinoprostone; Disease Models, Animal; Endothelins; Enzyme Inhibitors; Gene Expression Regulation; Hyperalgesia; Infliximab; Interleukin-17; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Pain Threshold; Polysaccharides; Receptors, Tumor Necrosis Factor, Type I; Serum Albumin; Zymosan | 2010 |
Enhancement of antinociception by coadministration of minocycline and a non-steroidal anti-inflammatory drug indomethacin in naïve mice and murine models of LPS-induced thermal hyperalgesia and monoarthritis.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Hyperalgesia; Indomethacin; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Minocycline; Treatment Outcome | 2010 |
A novel series of potent and selective EP(4) receptor ligands: facile modulation of agonism and antagonism.
Topics: Animals; Arthritis; Drug Evaluation, Preclinical; Hyperalgesia; Indoles; Ligands; Rats; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Structure-Activity Relationship | 2011 |
Protective effect of proteins derived from the latex of Calotropis procera against inflammatory hyperalgesia in monoarthritic rats.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Calotropis; Carrageenan; Diclofenac; Edema; Female; Freund's Adjuvant; Hyperalgesia; Injections, Intra-Articular; Joints; Latex; Male; Oxidative Stress; Plant Proteins; Rats, Wistar | 2011 |
Imaging studies in Freund's complete adjuvant model of regional polyarthritis, a model suitable for the study of pain mechanisms, in the rat.
Topics: Animals; Arthritis; Disease Models, Animal; Freund's Adjuvant; Hyperalgesia; Male; Pain; Radiography; Rats; Rats, Sprague-Dawley; Spinal Cord | 2011 |
The kappa opioid receptor agonist SA14867 has antinociceptive and weak sedative effects in models of acute and chronic pain.
Topics: Acetamides; Acute Pain; Analgesics; Animals; Arthritis; Chronic Pain; Disease Models, Animal; Hyperalgesia; Hypnotics and Sedatives; Ligation; Male; Mice; Morphine; Neuralgia; Pain Threshold; Pyrrolidines; Receptors, Opioid, kappa; Sciatic Nerve; Stress, Physiological; Tartrates; Temperature; Thiazoles | 2011 |
Gabapentin reduces CX3CL1 signaling and blocks spinal microglial activation in monoarthritic rats.
Topics: Amines; Animals; Arthritis; Calcium Channels, L-Type; Chemokine CX3CL1; CX3C Chemokine Receptor 1; Cyclohexanecarboxylic Acids; Disease Models, Animal; Freund's Adjuvant; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Injections, Intra-Articular; Injections, Intraperitoneal; Lumbar Vertebrae; Male; Microglia; Models, Biological; Pain; Posterior Horn Cells; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, Chemokine; Signal Transduction; Spinal Cord; Time Factors | 2012 |
MRI of hand and foot joints of patients with anticitrullinated peptide antibody positive arthralgia without clinical arthritis.
Topics: Arthralgia; Arthritis; Autoantibodies; Bone Marrow; Edema; Female; Finger Joint; Humans; Hyperalgesia; Magnetic Resonance Imaging; Male; Middle Aged; Peptides, Cyclic; Synovitis; Toe Joint | 2013 |
Analgesic effect of the neuropeptide cortistatin in murine models of arthritic inflammatory pain.
Topics: Analgesia; Animals; Arthritis; Calcitonin Gene-Related Peptide; Central Nervous System Sensitization; Disease Models, Animal; Drug Therapy, Combination; Female; Freund's Adjuvant; Ghrelin; GTP-Binding Protein alpha Subunits; Hyperalgesia; Injections, Intra-Articular; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuropeptides; Pain; Pain Threshold; Protein Binding; Receptors, Ghrelin; Receptors, Somatostatin; Somatostatin; Stifle; Tumor Necrosis Factor-alpha | 2013 |
Up-regulation and trafficking of delta opioid receptor in a model of chronic inflammation: implications for pain control.
Topics: Animals; Arthritis; Behavior, Animal; Chronic Disease; Disease Models, Animal; Freund's Adjuvant; Gene Expression; Hyperalgesia; Male; Microscopy, Electron; Neurogenic Inflammation; Neurons; Nociceptors; Oligopeptides; Pain, Postoperative; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; RNA, Messenger; Spinal Cord; Up-Regulation | 2003 |
Allodynia and hyperalgesia in adjuvant-induced arthritic rats: time course of progression and efficacy of analgesics.
Topics: Adjuvants, Immunologic; Analgesics; Animals; Arthritis; Disease Progression; Hyperalgesia; Pain; Pain Measurement; Rats; Time Factors; Treatment Outcome | 2003 |
Thermal hyperalgesia and light touch allodynia after intradermal Mycobacterium butyricum administration in rat.
Topics: Animals; Arthritis; Body Temperature; Disease Models, Animal; Hyperalgesia; Inflammation; Injections, Intradermal; Male; Mycobacterium; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Somatosensory Disorders; Time | 2003 |
Effects of experimentally induced inflammation on temporomandibular joint nociceptors in rats.
Topics: Action Potentials; Animals; Arthralgia; Arthritis; Bradykinin; Carrageenan; Disease Models, Animal; Hyperalgesia; Kaolin; Mechanoreceptors; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Nociceptors; Pain Threshold; Physical Stimulation; Rats; Rats, Wistar; Sensory Receptor Cells; Temporomandibular Joint; Temporomandibular Joint Disorders | 2004 |
Imbalance between the expression of NK1 and GABAB receptors in nociceptive spinal neurons during secondary hyperalgesia: a c-Fos study in the monoarthritic rat.
Topics: Animals; Arthritis; Disease Models, Animal; Freund's Adjuvant; Hyperalgesia; Immunohistochemistry; Male; Neurons, Afferent; Nociceptors; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, GABA-B; Receptors, Neurokinin-1; Spinal Cord | 2005 |
Lacosamide displays potent antinociceptive effects in animal models for inflammatory pain.
Topics: Acetamides; Animals; Arthritis; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Formaldehyde; Hot Temperature; Hyperalgesia; Lacosamide; Male; Mice; Pain; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reaction Time; Touch | 2006 |
The differential contribution of tumour necrosis factor to thermal and mechanical hyperalgesia during chronic inflammation.
Topics: Animals; Arthritis; Ganglia, Spinal; Hot Temperature; Hyperalgesia; Inflammation; Male; Physical Stimulation; Rats; Rats, Wistar; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Tumor Necrosis Factor-alpha | 2005 |
Disruption of glial function enhances electroacupuncture analgesia in arthritic rats.
Topics: Analysis of Variance; Animals; Arthritis; Citrates; Disease Models, Animal; Dose-Response Relationship, Drug; Electroacupuncture; Freund's Adjuvant; Functional Laterality; Hyperalgesia; Male; Neuroglia; Pain; Pain Management; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Reaction Time; Time Factors | 2006 |
Sex differences in inflammation and inflammatory pain in cyclooxygenase-deficient mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cyclooxygenase 1; Cyclooxygenase 2; Edema; Female; Hyperalgesia; Inflammation; Joints; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pain; Pain Measurement; Prostaglandin-Endoperoxide Synthases; Sex Characteristics | 2006 |
Secondary hyperalgesia in the monoarthritic rat is mediated by GABAB and NK1 receptors of spinal dorsal horn neurons: a behavior and c-fos study.
Topics: Animals; Arthritis; Baclofen; Behavior, Animal; Drug Interactions; Freund's Adjuvant; GABA Agonists; Gene Expression; Hyperalgesia; Immunohistochemistry; Male; Pain Measurement; Pain Threshold; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, GABA-B; Receptors, Neurokinin-1; Ribosome Inactivating Proteins, Type 1; Saporins; Substance P | 2006 |
Joint mobilization reduces hyperalgesia associated with chronic muscle and joint inflammation in rats.
Topics: Animals; Arthritis; Carrageenan; Chronic Disease; Hyperalgesia; Joints; Kaolin; Male; Myositis; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley | 2006 |
New evidence for the involvement of spinal fractalkine receptor in pain facilitation and spinal glial activation in rat model of monoarthritis.
Topics: Analysis of Variance; Animals; Arthritis; CX3C Chemokine Receptor 1; Disease Models, Animal; Freund's Adjuvant; Gene Expression Regulation; Hyperalgesia; Male; Neuroglia; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Cytokine; Receptors, HIV; Spinal Cord | 2007 |
Rimonabant: more than an anti-obesity drug?
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Obesity Agents; Arthritis; Humans; Hyperalgesia; Inflammation; Obesity; Pain Measurement; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant | 2007 |
Pressure application measurement (PAM): a novel behavioural technique for measuring hypersensitivity in a rat model of joint pain.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Arthritis; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Functional Laterality; Hyperalgesia; Male; Pain Measurement; Pain Threshold; Physical Stimulation; Pressure; Rats; Rats, Wistar; Reaction Time; Time Factors | 2007 |
Temporomandibular joint inflammation decreases the voltage-gated K+ channel subtype 1.4-immunoreactivity of trigeminal ganglion neurons in rats.
Topics: Animals; Arthritis; Cell Size; Freund's Adjuvant; Hyperalgesia; Immunohistochemistry; Kv1.4 Potassium Channel; Male; Neurons; Rats; Rats, Wistar; Temporomandibular Joint; Trigeminal Ganglion | 2008 |
The evolution of primary hyperalgesia in orthopedic surgery: quantitative sensory testing and clinical evaluation before and after total knee arthroplasty.
Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Arthritis; Arthroplasty, Replacement, Knee; Female; Hot Temperature; Humans; Hyperalgesia; Knee; Male; Morphine; Pain Measurement; Pain Threshold; Pain, Postoperative; Postoperative Care; Preoperative Care; Prospective Studies; Severity of Illness Index; Time Factors; Treatment Outcome | 2007 |
Collagen-induced arthritis as a model of hyperalgesia: functional and cellular analysis of the analgesic actions of tumor necrosis factor blockade.
Topics: Animals; Arthritis; Astrocytes; Behavior, Animal; Celecoxib; Collagen; Cyclooxygenase Inhibitors; Disease Models, Animal; Glial Fibrillary Acidic Protein; Hyperalgesia; Male; Mice; Mice, Inbred DBA; Microglia; Pain; Pyrazoles; Sulfonamides; Tumor Necrosis Factor-alpha | 2007 |
Role of ASIC3 in the primary and secondary hyperalgesia produced by joint inflammation in mice.
Topics: Acid Sensing Ion Channels; Afferent Pathways; Animals; Arthritis; Hyperalgesia; Knee Joint; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Sodium Channels | 2008 |
Modulation between high- and low-frequency transcutaneous electric nerve stimulation delays the development of analgesic tolerance in arthritic rats.
Topics: Analgesics; Analysis of Variance; Animals; Arthritis; Disease Models, Animal; Drug Tolerance; Hyperalgesia; Knee Joint; Male; Pain Measurement; Pain Threshold; Probability; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Statistics, Nonparametric; Time Factors; Transcutaneous Electric Nerve Stimulation | 2008 |
The induction of des-Arg9-bradykinin-mediated hyperalgesia in the rat by inflammatory stimuli.
Topics: Animals; Arthritis; Bradykinin; Bradykinin Receptor Antagonists; Freund's Adjuvant; Hyperalgesia; Injections, Intra-Articular; Injections, Intravenous; Interleukin-1; Rats; Reaction Time; Receptors, Bradykinin; Ultraviolet Rays | 1994 |
Inflammation-induced release of excitatory amino acids is prevented by spinal administration of a GABAA but not by a GABAB receptor antagonist in rats.
Topics: Animals; Arthritis; Aspartic Acid; Bicuculline; Excitatory Amino Acids; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Glutamic Acid; Hyperalgesia; Organophosphorus Compounds; Rats; Receptors, GABA-A; Receptors, GABA-B; Spinal Cord | 1994 |
Hyperalgesic change over the craniofacial area following urate crystal injection into the rabbit's temporomandibular joint.
Topics: Analysis of Variance; Animals; Arthritis; Facial Pain; Female; Hyperalgesia; Male; Masticatory Muscles; Pain Threshold; Rabbits; Temporomandibular Joint Disorders; Uric Acid | 1994 |
Joint inflammation and hyperalgesia are reduced by spinal bicuculline.
Topics: Animals; Arthritis; Behavior, Animal; Bicuculline; Carrageenan; GABA Antagonists; Hot Temperature; Hyperalgesia; Injections; Kaolin; Microdialysis; Organophosphorus Compounds; Rats; Receptors, GABA; Spinal Cord | 1993 |
The role of spinal neurokinin-2 receptors in the processing of nociceptive information from the joint and in the generation and maintenance of inflammation-evoked hyperexcitability of dorsal horn neurons in the rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arthritis; Benzamides; Carrageenan; Hyperalgesia; Iontophoresis; Kaolin; Knee Joint; Male; Neurokinin A; Nociceptors; Pain; Piperidines; Pressure; Rats; Rats, Wistar; Receptors, Neurokinin-2; Spinal Cord; Substance P | 1996 |
Changes in nociceptive reflex facilitation during carrageenan-induced arthritis.
Topics: Action Potentials; Animals; Arthritis; Carrageenan; Electric Stimulation; Electrophysiology; Female; Hyperalgesia; Knee Joint; Nociceptors; Rats; Rats, Wistar; Reflex; Time Factors | 1996 |
An I2 imidazoline ligand, RS 45041, potentiates hyperalgesia in acute arthritis.
Topics: Acute Disease; Adrenergic alpha-Antagonists; Animals; Arthritis; Drug Evaluation, Preclinical; Drug Synergism; Hyperalgesia; Idazoxan; Imidazoles; Imidazoline Receptors; Indoles; Injections, Spinal; Isoindoles; Neural Inhibition; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Drug | 1996 |
Differential roles of neurokinin 1 and neurokinin 2 receptors in the development and maintenance of heat hyperalgesia induced by acute inflammation.
Topics: Animals; Arthritis; Hot Temperature; Hyperalgesia; Male; Microdialysis; Neurokinin-1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-2 | 1997 |
Blockade of joint inflammation and secondary hyperalgesia by L-NAME, a nitric oxide synthase inhibitor.
Topics: Analgesics; Animals; Arthritis; Carrageenan; Hyperalgesia; Indazoles; Inflammation; Injections, Intra-Articular; Isomerism; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 1997 |
Bradykinin-induced knee joint incapacitation involves bradykinin B2 receptor mediated hyperalgesia and bradykinin B1 receptor-mediated nociception.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Behavior, Animal; Bradykinin; Bradykinin Receptor Antagonists; Dinoprostone; Hindlimb; Hyperalgesia; Indomethacin; Joints; Male; Nociceptors; Pain Measurement; Rats; Rats, Wistar; Receptors, Bradykinin | 1997 |
Cyclosporin inhibits hyperalgesia and edema in arthritic rats: role of the central nervous system.
Topics: Animals; Arthritis; Central Nervous System; Cyclosporine; Edema; Female; Hyperalgesia; Rats; Rats, Sprague-Dawley | 1997 |
S-(+)-3-isobutylgaba and its stereoisomer reduces the amount of inflammation and hyperalgesia in an acute arthritis model in the rat.
Topics: Acute Disease; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; gamma-Aminobutyric Acid; Hyperalgesia; Male; Pregabalin; Rats; Rats, Sprague-Dawley; Spinal Cord; Stereoisomerism | 1998 |
Blockade of N- and P/Q-type calcium channels reduces the secondary heat hyperalgesia induced by acute inflammation.
Topics: Animals; Arthritis; Calcium Channel Blockers; Calcium Channels; Hot Temperature; Hyperalgesia; Male; Microdialysis; Nifedipine; omega-Agatoxin IVA; omega-Conotoxins; Pain; Peptides; Rats; Rats, Sprague-Dawley; Spider Venoms | 1998 |
Effect of brain-derived neurotrophic factor on the release of substance P from rat spinal cord.
Topics: Animals; Arthritis; Brain-Derived Neurotrophic Factor; Electric Stimulation; Hyperalgesia; Knee Joint; Male; Posterior Horn Cells; Rats; Rats, Wistar; Spinal Cord; Substance P; Touch | 2001 |
Bee venom injection into an acupuncture point reduces arthritis associated edema and nociceptive responses.
Topics: Acupuncture Points; Animals; Arthritis; Bee Venoms; Edema; Hot Temperature; Hyperalgesia; Male; Pain; Rats; Rats, Sprague-Dawley; Touch | 2001 |
Knee joint mobilization reduces secondary mechanical hyperalgesia induced by capsaicin injection into the ankle joint.
Topics: Animals; Ankle Joint; Arthritis; Capsaicin; Disease Models, Animal; Hyperalgesia; Injections, Intra-Articular; Knee Joint; Male; Movement; Physical Therapy Modalities; Rats; Rats, Sprague-Dawley | 2001 |
Therapeutic efficacy in experimental polyarthritis of viral-driven enkephalin overproduction in sensory neurons.
Topics: Animals; Arthritis; Arthritis, Experimental; Disease Models, Animal; Disease Progression; Enkephalins; Freund's Adjuvant; Ganglia, Spinal; Genes, Reporter; Genetic Therapy; Genetic Vectors; Herpesvirus 1, Human; Hindlimb; Hyperalgesia; Male; Neurons, Afferent; Pain Measurement; Protein Precursors; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Terminal Repeat Sequences; Treatment Outcome | 2001 |
Therapeutic administration of nitric oxide synthase inhibitors reverses hyperalgesia but not inflammation in a rat model of polyarthritis.
Topics: Animals; Arthritis; Body Weight; Cyclooxygenase Inhibitors; Disease Models, Animal; Enzyme Inhibitors; Female; Hot Temperature; Hyperalgesia; Indomethacin; Lysine; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Physical Stimulation; Rats; Rats, Inbred Lew | 2002 |