Page last updated: 2024-11-05

troglitazone and Ventricular Fibrillation

troglitazone has been researched along with Ventricular Fibrillation in 1 studies

Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.

Ventricular Fibrillation: A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.

Research Excerpts

ExcerptRelevanceReference
"Troglitazone treatment improved ischemic tolerance by improving glucose metabolism in the myocardium of those rats."1.34Exacerbation of acidosis during ischemia and reperfusion arrhythmia in hearts from type 2 Diabetic Otsuka Long-Evans Tokushima Fatty rats. ( Anzawa, R; Horikoshi, K; Mochizuki, S; Seki, S; Taniguchi, M, 2007)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anzawa, R1
Seki, S1
Horikoshi, K1
Taniguchi, M1
Mochizuki, S1

Other Studies

1 other study available for troglitazone and Ventricular Fibrillation

ArticleYear
Exacerbation of acidosis during ischemia and reperfusion arrhythmia in hearts from type 2 Diabetic Otsuka Long-Evans Tokushima Fatty rats.
    Cardiovascular diabetology, 2007, Jun-05, Volume: 6

    Topics: Animals; Arrhythmias, Cardiac; Blood Glucose; Chromans; Diabetes Mellitus, Type 2; Diabetic Ketoacid

2007