troglitazone has been researched along with Uterine Neoplasms in 2 studies
Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.
Uterine Neoplasms: Tumors or cancer of the UTERUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Human leiomyomas were also found to express all three PPAR isoforms, and primary cultures of these cells were sensitive to the inhibitory effects of PPARgamma ligands." | 1.32 | Inhibition of proliferation and estrogen receptor signaling by peroxisome proliferator-activated receptor gamma ligands in uterine leiomyoma. ( Broaddus, RR; Copland, JA; Fischer, SM; Gottardis, MM; Houston, KD; Walker, CL, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Houston, KD | 1 |
| Copland, JA | 1 |
| Broaddus, RR | 1 |
| Gottardis, MM | 1 |
| Fischer, SM | 1 |
| Walker, CL | 1 |
| Tsibris, JC | 1 |
| Porter, KB | 1 |
| Jazayeri, A | 1 |
| Tzimas, G | 1 |
| Nau, H | 1 |
| Huang, H | 1 |
| Kuparadze, K | 1 |
| Porter, GW | 1 |
| O'Brien, WF | 1 |
| Spellacy, WN | 1 |
2 other studies available for troglitazone and Uterine Neoplasms
| Article | Year |
|---|---|
Inhibition of proliferation and estrogen receptor signaling by peroxisome proliferator-activated receptor gamma ligands in uterine leiomyoma.
Topics: Animals; Cell Division; Chromans; Docosahexaenoic Acids; Estradiol; Female; Humans; Leiomyoma; Ligan | 2003 |
Human uterine leiomyomata express higher levels of peroxisome proliferator-activated receptor gamma, retinoid X receptor alpha, and all-trans retinoic acid than myometrium.
Topics: Alitretinoin; Animals; Carcinogens; Chromans; Drug Implants; Estradiol; Female; Guinea Pigs; Humans; | 1999 |