troglitazone has been researched along with Trypanosomiasis, African in 2 studies
Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.
Trypanosomiasis, African: A disease endemic among people and animals in Central Africa. It is caused by various species of trypanosomes, particularly T. gambiense and T. rhodesiense. Its second host is the TSETSE FLY. Involvement of the central nervous system produces African sleeping sickness. Nagana is a rapidly fatal trypanosomiasis of horses and other animals.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fueyo González, FJ | 1 |
| Ebiloma, GU | 1 |
| Izquierdo García, C | 1 |
| Bruggeman, V | 1 |
| Sánchez Villamañán, JM | 1 |
| Donachie, A | 1 |
| Balogun, EO | 1 |
| Inaoka, DK | 1 |
| Shiba, T | 1 |
| Harada, S | 1 |
| Kita, K | 1 |
| de Koning, HP | 1 |
| Dardonville, C | 1 |
| Denninger, V | 1 |
| Figarella, K | 1 |
| Schönfeld, C | 1 |
| Brems, S | 1 |
| Busold, C | 1 |
| Lang, F | 1 |
| Hoheisel, J | 1 |
| Duszenko, M | 1 |
2 other studies available for troglitazone and Trypanosomiasis, African
| Article | Year |
|---|---|
Conjugates of 2,4-Dihydroxybenzoate and Salicylhydroxamate and Lipocations Display Potent Antiparasite Effects by Efficiently Targeting the Trypanosoma brucei and Trypanosoma congolense Mitochondrion.
Topics: Cell Line; Drug Discovery; Humans; Hydroxybenzoates; Membrane Potential, Mitochondrial; Mitochondria | 2017 |
Troglitazone induces differentiation in Trypanosoma brucei.
Topics: Animals; Biomarkers; Cell Differentiation; Cell Respiration; Cell Shape; Chromans; Cytochromes; Ener | 2007 |