troglitazone has been researched along with Syndrome in 7 studies
Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.
Syndrome: A characteristic symptom complex.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Troglitazone promotes adipocyte differentiation in vitro and increases insulin sensitivity in vivo." | 9.09 | Efficacy and safety of troglitazone in the treatment of lipodystrophy syndromes. ( Arioglu, E; Duncan-Morin, J; Gottlieb, N; Herion, D; Hoofnagle, J; Kleiner, DE; Lieberman, J; Premkumar, A; Reitman, ML; Reynolds, J; Rother, KI; Sebring, N; Sumner, AE; Taylor, SI, 2000) |
| "Troglitazone promotes adipocyte differentiation in vitro and increases insulin sensitivity in vivo." | 5.09 | Efficacy and safety of troglitazone in the treatment of lipodystrophy syndromes. ( Arioglu, E; Duncan-Morin, J; Gottlieb, N; Herion, D; Hoofnagle, J; Kleiner, DE; Lieberman, J; Premkumar, A; Reitman, ML; Reynolds, J; Rother, KI; Sebring, N; Sumner, AE; Taylor, SI, 2000) |
| "Troglitazone, a newly introduced insulin sensitizer, has been implicated in prevention and treatment of atherosclerotic cardiovascular disease especially associated with type 2 diabetes mellitus and insulin resistance." | 4.80 | [Cardiovascular effects of the thiazolidinedione troglitazone]. ( Kuzuya, H; Nakano, T; Yamada, K, 2000) |
| "Insulin resistance syndrome is the theory that glucose intolerance, hyperinsulinemia, increased very low density lipoprotein triglyceride level, decreased high density lipoprotein cholesterol level, and hypertension are proposed consequences of insulin resistance." | 2.41 | [Insulin sensitizer and hypertension]. ( Shimamoto, K, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shimamoto, K | 1 |
| Iwatani, M | 1 |
| Wasada, T | 1 |
| Iwamoto, Y | 1 |
| Kamatani, N | 1 |
| Yamada, K | 1 |
| Kuzuya, H | 1 |
| Nakano, T | 1 |
| Arioglu, E | 1 |
| Duncan-Morin, J | 1 |
| Sebring, N | 1 |
| Rother, KI | 1 |
| Gottlieb, N | 1 |
| Lieberman, J | 1 |
| Herion, D | 1 |
| Kleiner, DE | 1 |
| Reynolds, J | 1 |
| Premkumar, A | 1 |
| Sumner, AE | 1 |
| Hoofnagle, J | 1 |
| Reitman, ML | 1 |
| Taylor, SI | 1 |
| Ganda, OP | 1 |
| Cheng, JS | 1 |
| Marcus, AO | 1 |
4 reviews available for troglitazone and Syndrome
| Article | Year |
|---|---|
[Insulin sensitizer and hypertension].
Topics: Animals; Cholesterol, HDL; Cholesterol, LDL; Chromans; Humans; Hyperinsulinism; Hypertension; Hypogl | 2000 |
[Insulin sensitizer and urate metabolism].
Topics: Chromans; Diabetes Mellitus, Type 2; Female; Glucose; Gout; Humans; Hyperlipidemias; Hypertension; H | 2000 |
[Cardiovascular effects of the thiazolidinedione troglitazone].
Topics: Animals; Arteriosclerosis; Cardiovascular Diseases; Cardiovascular System; Chromans; Diabetes Mellit | 2000 |
Safety of drugs commonly used to treat hypertension, dyslipidemia, and Type 2 diabetes (the metabolic syndrome): part 2.
Topics: Acarbose; Cardiovascular Diseases; Chromans; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Human | 2000 |
1 trial available for troglitazone and Syndrome
| Article | Year |
|---|---|
Efficacy and safety of troglitazone in the treatment of lipodystrophy syndromes.
Topics: Adipose Tissue; Adult; Aged; Body Composition; Chemical and Drug Induced Liver Injury; Child; Chroma | 2000 |
2 other studies available for troglitazone and Syndrome
| Article | Year |
|---|---|
Lipoatrophy, lipodystrophy, and insulin resistance.
Topics: Body Composition; Chromans; Diabetes Mellitus, Lipoatrophic; Humans; Hypoglycemic Agents; Insulin Re | 2000 |
Treatment of lipodystrophy with troglitazone.
Topics: Adipose Tissue; Antioxidants; Chromans; Humans; Lipodystrophy; Respiration; Syndrome; Thiazoles; Thi | 2001 |