troglitazone has been researched along with Reperfusion Injury in 4 studies
Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Troglitazone treatment improved ischemic tolerance by improving glucose metabolism in the myocardium of those rats." | 1.34 | Exacerbation of acidosis during ischemia and reperfusion arrhythmia in hearts from type 2 Diabetic Otsuka Long-Evans Tokushima Fatty rats. ( Anzawa, R; Horikoshi, K; Mochizuki, S; Seki, S; Taniguchi, M, 2007) |
| "Renal ischemia-reperfusion injury affects the long-term outcome of renal graft survival." | 1.34 | Protective effects of peroxisome proliferator-activated receptor gamma ligand on apoptosis and hepatocyte growth factor induction in renal ischemia-reperfusion injury. ( Arakawa, T; Doi, S; Kawai, T; Kohno, N; Masaki, T; Naito, T; Nakashima, A; Takahashi, S; Yorioka, N, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Okada, M | 1 |
| Yan, SF | 1 |
| Pinsky, DJ | 1 |
| Naito, Y | 1 |
| Yoshikawa, T | 1 |
| Anzawa, R | 1 |
| Seki, S | 1 |
| Horikoshi, K | 1 |
| Taniguchi, M | 1 |
| Mochizuki, S | 1 |
| Doi, S | 1 |
| Masaki, T | 1 |
| Arakawa, T | 1 |
| Takahashi, S | 1 |
| Kawai, T | 1 |
| Nakashima, A | 1 |
| Naito, T | 1 |
| Kohno, N | 1 |
| Yorioka, N | 1 |
1 review available for troglitazone and Reperfusion Injury
| Article | Year |
|---|---|
Thiazolidinediones: a new class of drugs for the therapy of ischemia-reperfusion injury.
Topics: Animals; Anti-Inflammatory Agents; Chromans; Humans; Ligands; Pioglitazone; Receptors, Cytoplasmic a | 2004 |
3 other studies available for troglitazone and Reperfusion Injury
| Article | Year |
|---|---|
Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) activation suppresses ischemic induction of Egr-1 and its inflammatory gene targets.
Topics: Animals; Cell Line; Cell Movement; Chromans; Cytokines; DNA-Binding Proteins; Early Growth Response | 2002 |
Exacerbation of acidosis during ischemia and reperfusion arrhythmia in hearts from type 2 Diabetic Otsuka Long-Evans Tokushima Fatty rats.
Topics: Animals; Arrhythmias, Cardiac; Blood Glucose; Chromans; Diabetes Mellitus, Type 2; Diabetic Ketoacid | 2007 |
Protective effects of peroxisome proliferator-activated receptor gamma ligand on apoptosis and hepatocyte growth factor induction in renal ischemia-reperfusion injury.
Topics: Acute Kidney Injury; Animals; Apoptosis; Blotting, Western; Caspase 3; Chromans; Creatinine; Disease | 2007 |