troglitazone has been researched along with Non-alcoholic Fatty Liver Disease in 3 studies
Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.
Non-alcoholic Fatty Liver Disease: Fatty liver finding without excessive ALCOHOL CONSUMPTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nonalcoholic steatohepatitis (NASH) is caused by an elevation in oxidative stress, which might further lead to hepatic fibrogenesis." | 1.38 | Synergistic effect of cyanidin and PPAR agonist against nonalcoholic steatohepatitis-mediated oxidative stress-induced cytotoxicity through MAPK and Nrf2 transduction pathways. ( Hwang, SL; Shih, PH; Yeh, CT; Yen, GC, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Shim, S | 1 |
| Krishnaiah, M | 1 |
| Sankham, MR | 1 |
| Kim, I | 1 |
| Lee, Y | 1 |
| Shin, I | 1 |
| Oh, AR | 1 |
| Lee, HJ | 1 |
| Vu, TNL | 1 |
| Park, J | 1 |
| Choi, S | 1 |
| Park, S | 1 |
| Kwon, Y | 1 |
| Fang, S | 1 |
| Kim, DK | 1 |
| Shih, PH | 1 |
| Hwang, SL | 1 |
| Yeh, CT | 1 |
| Yen, GC | 1 |
| Wagnerberger, S | 1 |
| Spruss, A | 1 |
| Kanuri, G | 1 |
| Stahl, C | 1 |
| Schröder, M | 1 |
| Vetter, W | 1 |
| Bischoff, SC | 1 |
| Bergheim, I | 1 |
3 other studies available for troglitazone and Non-alcoholic Fatty Liver Disease
| Article | Year |
|---|---|
Discovery of (
Topics: Acrylates; Animals; Bile Acids and Salts; Esters; Intestines; Liver; Mice; Non-alcoholic Fatty Liver | 2022 |
Synergistic effect of cyanidin and PPAR agonist against nonalcoholic steatohepatitis-mediated oxidative stress-induced cytotoxicity through MAPK and Nrf2 transduction pathways.
Topics: Animals; Anthocyanins; Cell Line, Tumor; Chromans; Drug Synergism; Extracellular Signal-Regulated MA | 2012 |
Lactobacillus casei Shirota protects from fructose-induced liver steatosis: a mouse model.
Topics: Alanine Transaminase; Animals; Butyrates; Cell Line; Cell Proliferation; Chromans; Disease Models, A | 2013 |