troglitazone has been researched along with Myotonic Dystrophy in 2 studies
Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.
Myotonic Dystrophy: Neuromuscular disorder characterized by PROGRESSIVE MUSCULAR ATROPHY; MYOTONIA, and various multisystem atrophies. Mild INTELLECTUAL DISABILITY may also occur. Abnormal TRINUCLEOTIDE REPEAT EXPANSION in the 3' UNTRANSLATED REGIONS of DMPK PROTEIN gene is associated with Myotonic Dystrophy 1. DNA REPEAT EXPANSION of zinc finger protein-9 gene intron is associated with Myotonic Dystrophy 2.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kono, S | 1 |
| Kashiwagi, K | 1 |
| Nagafuchi, S | 1 |
| Sekiguchi, N | 1 |
| Yamagata, A | 1 |
| Iwata, I | 1 |
| Furuya, H | 1 |
| Kato, M | 1 |
| Niho, Y | 1 |
1 review available for troglitazone and Myotonic Dystrophy
| Article | Year |
|---|---|
[Insulin resistance in myotonic dystrophy].
Topics: Chromans; Humans; Hyperinsulinism; Insulin Resistance; Insulin-Like Growth Factor I; Myotonic Dystro | 2002 |
1 other study available for troglitazone and Myotonic Dystrophy
| Article | Year |
|---|---|
Troglitazone not only reduced insulin resistance but also improved myotonia in a patient with myotonic dystrophy.
Topics: Adult; Chromans; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Myotonic Dystrophy; Thiazo | 1999 |