Page last updated: 2024-11-05

troglitazone and Muscle Relaxation

troglitazone has been researched along with Muscle Relaxation in 4 studies

Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.

Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.

Research Excerpts

ExcerptRelevanceReference
" The aim was to define the insulin-sensitizing effects of S15261, the cleavage products, and troglitazone and metformin in the JCR:LA-cp rat, an animal model of the obesity/insulin resistance syndrome that exhibits an associated vasculopathy and cardiovascular disease."3.70Beneficial insulin-sensitizing and vascular effects of S15261 in the insulin-resistant JCR:LA-cp rat. ( Brindley, DN; Davidge, ST; Delrat, P; Jochemsen, R; Kelly, SE; O'Brien, SF; Pégorier, JP; Ravel, D; Russell, JC, 2000)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's3 (75.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Iida, KT1
Kawakami, Y1
Suzuki, M1
Shimano, H1
Toyoshima, H1
Sone, H1
Shimada, K1
Iwama, Y1
Watanabe, Y1
Mokuno, H1
Kamata, K1
Yamada, N1
Peuler, JD1
Warfield, RK1
Phelps, LE1
Osanai, H1
Toki, Y1
Nakashima, Y1
Okumura, K1
Ito, T1
Hayakawa, T1
Russell, JC1
Ravel, D1
Pégorier, JP1
Delrat, P1
Jochemsen, R1
O'Brien, SF1
Kelly, SE1
Davidge, ST1
Brindley, DN1

Other Studies

4 other studies available for troglitazone and Muscle Relaxation

ArticleYear
Effect of thiazolidinediones and metformin on LDL oxidation and aortic endothelium relaxation in diabetic GK rats.
    American journal of physiology. Endocrinology and metabolism, 2003, Volume: 284, Issue:6

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Arteriosclerosis; Cholesterol, LDL; Chromans; Diabetes Mell

2003
Attenuation by 4-aminopyridine of delayed vasorelaxation by troglitazone.
    Metabolism: clinical and experimental, 2004, Volume: 53, Issue:2

    Topics: 4-Aminopyridine; Animals; Arginine Vasopressin; Arteries; Chromans; Dose-Response Relationship, Drug

2004
Reduction of vascular tone by introduction of troglitazone to the canine coronary artery.
    Arzneimittel-Forschung, 1999, Volume: 49, Issue:1

    Topics: Animals; Chromans; Coronary Vessels; Depression, Chemical; Dinoprost; Dogs; Female; In Vitro Techniq

1999
Beneficial insulin-sensitizing and vascular effects of S15261 in the insulin-resistant JCR:LA-cp rat.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 295, Issue:2

    Topics: Animals; Blood Glucose; Body Weight; Chromans; Eating; Fluorenes; Gene Expression; Glucose Tolerance

2000