troglitazone has been researched along with Lipodystrophy in 6 studies
Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.
Lipodystrophy: A collection of heterogenous conditions resulting from defective LIPID METABOLISM and characterized by ADIPOSE TISSUE atrophy. Often there is redistribution of body fat resulting in peripheral fat wasting and central adiposity. They include generalized, localized, congenital, and acquired lipodystrophy.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Troglitazone promotes adipocyte differentiation in vitro and increases insulin sensitivity in vivo." | 9.09 | Efficacy and safety of troglitazone in the treatment of lipodystrophy syndromes. ( Arioglu, E; Duncan-Morin, J; Gottlieb, N; Herion, D; Hoofnagle, J; Kleiner, DE; Lieberman, J; Premkumar, A; Reitman, ML; Reynolds, J; Rother, KI; Sebring, N; Sumner, AE; Taylor, SI, 2000) |
| "Troglitazone promotes adipocyte differentiation in vitro and increases insulin sensitivity in vivo." | 5.09 | Efficacy and safety of troglitazone in the treatment of lipodystrophy syndromes. ( Arioglu, E; Duncan-Morin, J; Gottlieb, N; Herion, D; Hoofnagle, J; Kleiner, DE; Lieberman, J; Premkumar, A; Reitman, ML; Reynolds, J; Rother, KI; Sebring, N; Sumner, AE; Taylor, SI, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gura, T | 1 |
| Arioglu, E | 1 |
| Duncan-Morin, J | 1 |
| Sebring, N | 1 |
| Rother, KI | 1 |
| Gottlieb, N | 1 |
| Lieberman, J | 1 |
| Herion, D | 1 |
| Kleiner, DE | 1 |
| Reynolds, J | 1 |
| Premkumar, A | 1 |
| Sumner, AE | 1 |
| Hoofnagle, J | 1 |
| Reitman, ML | 1 |
| Taylor, SI | 1 |
| Ganda, OP | 1 |
| Harano, Y | 1 |
| Caldwell, SH | 1 |
| Cheng, JS | 1 |
1 review available for troglitazone and Lipodystrophy
| Article | Year |
|---|---|
[Lipodystrophia].
Topics: Animals; Cardiomyopathy, Hypertrophic; Chromans; Diabetes Mellitus; Diagnosis, Differential; Fatty L | 2001 |
1 trial available for troglitazone and Lipodystrophy
| Article | Year |
|---|---|
Efficacy and safety of troglitazone in the treatment of lipodystrophy syndromes.
Topics: Adipose Tissue; Adult; Aged; Body Composition; Chemical and Drug Induced Liver Injury; Child; Chroma | 2000 |
4 other studies available for troglitazone and Lipodystrophy
| Article | Year |
|---|---|
From fat-free mice, the skinny on diabetes.
Topics: Adipose Tissue; Animals; Chromans; Diabetes Mellitus, Type 2; Fatty Acids; Humans; Hypoglycemic Agen | 1998 |
Lipoatrophy, lipodystrophy, and insulin resistance.
Topics: Body Composition; Chromans; Diabetes Mellitus, Lipoatrophic; Humans; Hypoglycemic Agents; Insulin Re | 2000 |
Efficacy and safety of troglitazone for lipodystrophy syndromes.
Topics: Adipocytes; Chemical and Drug Induced Liver Injury; Chromans; Hepatocytes; Humans; Lipodystrophy; Mi | 2001 |
Treatment of lipodystrophy with troglitazone.
Topics: Adipose Tissue; Antioxidants; Chromans; Humans; Lipodystrophy; Respiration; Syndrome; Thiazoles; Thi | 2001 |