troglitazone has been researched along with Leukemia, Myeloid, Acute, M4 in 1 studies
Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a human eosinophilic leukemia cell line, EoL-1, cell proliferation was suppressed by 2-day treatment with troglitazone." | 1.30 | Troglitazone suppresses cell growth of myeloid leukemia cell lines by induction of p21WAF1/CIP1 cyclin-dependent kinase inhibitor. ( Kiriyama, Y; Nochi, H; Sakurada, Y; Sugimura, A; Tamoto, K; Tokumitsu, Y; Tsuchiya, H; Ui, M, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sugimura, A | 1 |
| Kiriyama, Y | 1 |
| Nochi, H | 1 |
| Tsuchiya, H | 1 |
| Tamoto, K | 1 |
| Sakurada, Y | 1 |
| Ui, M | 1 |
| Tokumitsu, Y | 1 |
1 other study available for troglitazone and Leukemia, Myeloid, Acute, M4
| Article | Year |
|---|---|
Troglitazone suppresses cell growth of myeloid leukemia cell lines by induction of p21WAF1/CIP1 cyclin-dependent kinase inhibitor.
Topics: Antineoplastic Agents; Cell Cycle; Cell Division; Chromans; Cyclin-Dependent Kinase Inhibitor p21; C | 1999 |