Page last updated: 2024-11-05

troglitazone and Left Ventricular Dysfunction

troglitazone has been researched along with Left Ventricular Dysfunction in 1 studies

Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.

Research Excerpts

ExcerptRelevanceReference
" We previously demonstrated that chronic pretreatment with a thiazolidinedione peroxisome proliferator-activated receptor (PPAR)-gamma activator, troglitazone, improves recovery of left ventricular (LV) function and substrate metabolism after ischemia and reperfusion, without causing arrhythmias."3.72Deleterious effects of acute treatment with a peroxisome proliferator-activated receptor-gamma activator in myocardial ischemia and reperfusion in pigs. ( Gen, M; Greyson, C; Kinugawa, K; Lee, J; Long, CS; Lu, L; Schwartz, GG; Xu, Y, 2003)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Xu, Y1
Lu, L1
Greyson, C1
Lee, J1
Gen, M1
Kinugawa, K1
Long, CS1
Schwartz, GG1

Other Studies

1 other study available for troglitazone and Left Ventricular Dysfunction

ArticleYear
Deleterious effects of acute treatment with a peroxisome proliferator-activated receptor-gamma activator in myocardial ischemia and reperfusion in pigs.
    Diabetes, 2003, Volume: 52, Issue:5

    Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Chromans; Disease Models, Animal; Gene Expression Reg

2003