troglitazone has been researched along with Keloid in 1 studies
Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.
Keloid: A sharply elevated, irregularly shaped, progressively enlarging scar resulting from formation of excessive amounts of collagen in the dermis during connective tissue repair. It is differentiated from a hypertrophic scar (CICATRIX, HYPERTROPHIC) in that the former does not spread to surrounding tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the effect of the PPAR-gamma agonist troglitazone on transforming growth factor (TGF)-beta1-induced collagen type I expression in keloid fibroblasts." | 7.75 | Troglitazone suppresses transforming growth factor-beta1-induced collagen type I expression in keloid fibroblasts. ( Chen, XL; Gao, WY; Guo, SZ; Li, X; Li, ZJ; Ma, B; Yi, CG; Zhang, GY, 2009) |
| "To investigate the effect of the PPAR-gamma agonist troglitazone on transforming growth factor (TGF)-beta1-induced collagen type I expression in keloid fibroblasts." | 3.75 | Troglitazone suppresses transforming growth factor-beta1-induced collagen type I expression in keloid fibroblasts. ( Chen, XL; Gao, WY; Guo, SZ; Li, X; Li, ZJ; Ma, B; Yi, CG; Zhang, GY, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, GY | 1 |
| Yi, CG | 1 |
| Li, X | 1 |
| Ma, B | 1 |
| Li, ZJ | 1 |
| Chen, XL | 1 |
| Guo, SZ | 1 |
| Gao, WY | 1 |
1 other study available for troglitazone and Keloid
| Article | Year |
|---|---|
Troglitazone suppresses transforming growth factor-beta1-induced collagen type I expression in keloid fibroblasts.
Topics: Adolescent; Adult; Blotting, Western; Chromans; Collagen Type I; Female; Fibroblasts; Fibrosis; Huma | 2009 |