troglitazone has been researched along with Interstitial Nephritis in 1 studies
Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Therefore, we investigated the anti-fibrotic and anti-inflammatory effects of the TZD troglitazone in the mouse model of unilateral ureteral obstruction (UUO)." | 3.75 | PPAR-gamma agonist attenuates renal interstitial fibrosis and inflammation through reduction of TGF-beta. ( Arakawa, T; Doi, S; Doi, T; Kawai, T; Kohno, N; Masaki, T; Yokoyama, Y; Yorioka, N, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kawai, T | 1 |
| Masaki, T | 1 |
| Doi, S | 1 |
| Arakawa, T | 1 |
| Yokoyama, Y | 1 |
| Doi, T | 1 |
| Kohno, N | 1 |
| Yorioka, N | 1 |
1 other study available for troglitazone and Interstitial Nephritis
| Article | Year |
|---|---|
PPAR-gamma agonist attenuates renal interstitial fibrosis and inflammation through reduction of TGF-beta.
Topics: Actins; Animals; Anti-Inflammatory Agents; Arterioles; Blood Glucose; Cell Proliferation; Chromans; | 2009 |