troglitazone has been researched along with Injury, Myocardial Reperfusion in 2 studies
Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We previously demonstrated that chronic pretreatment with a thiazolidinedione peroxisome proliferator-activated receptor (PPAR)-gamma activator, troglitazone, improves recovery of left ventricular (LV) function and substrate metabolism after ischemia and reperfusion, without causing arrhythmias." | 3.72 | Deleterious effects of acute treatment with a peroxisome proliferator-activated receptor-gamma activator in myocardial ischemia and reperfusion in pigs. ( Gen, M; Greyson, C; Kinugawa, K; Lee, J; Long, CS; Lu, L; Schwartz, GG; Xu, Y, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, Y | 2 |
| Lu, L | 2 |
| Greyson, C | 2 |
| Lee, J | 1 |
| Gen, M | 2 |
| Kinugawa, K | 1 |
| Long, CS | 2 |
| Schwartz, GG | 2 |
| Fox, J | 1 |
| Weiss, SO | 1 |
| Brown, RD | 1 |
| Perlov, D | 1 |
| Ahmad, H | 1 |
| Zhu, P | 1 |
2 other studies available for troglitazone and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Deleterious effects of acute treatment with a peroxisome proliferator-activated receptor-gamma activator in myocardial ischemia and reperfusion in pigs.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Chromans; Disease Models, Animal; Gene Expression Reg | 2003 |
PPAR-gamma activation fails to provide myocardial protection in ischemia and reperfusion in pigs.
Topics: alpha-Tocopherol; Animals; Antioxidants; Chromans; Coronary Circulation; Cytokines; Energy Metabolis | 2005 |