troglitazone has been researched along with Idiopathic Inflammatory Myopathies in 1 studies
Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 68-year-old woman, with type 2 diabetes mellitus, hypercholesterolemia, and prior long-term simvastatin therapy, self-resumed troglitazone after running out of metformin." | 7.71 | Myositis, microvesicular hepatitis, and progression to cirrhosis from troglitazone added to simvastatin. ( Caldwell, SH; Hespenheide, EE; von Borstel, RW, 2001) |
| "A 68-year-old woman, with type 2 diabetes mellitus, hypercholesterolemia, and prior long-term simvastatin therapy, self-resumed troglitazone after running out of metformin." | 3.71 | Myositis, microvesicular hepatitis, and progression to cirrhosis from troglitazone added to simvastatin. ( Caldwell, SH; Hespenheide, EE; von Borstel, RW, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Caldwell, SH | 1 |
| Hespenheide, EE | 1 |
| von Borstel, RW | 1 |
1 other study available for troglitazone and Idiopathic Inflammatory Myopathies
| Article | Year |
|---|---|
Myositis, microvesicular hepatitis, and progression to cirrhosis from troglitazone added to simvastatin.
Topics: Aged; Anticholesteremic Agents; Antioxidants; Chemical and Drug Induced Liver Injury; Chromans; Diab | 2001 |