troglitazone has been researched along with Hypertrophy in 2 studies
Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.
Hypertrophy: General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic administration of troglitazone might predispose to cardiac hypertrophy." | 7.70 | Troglitazone does not initiate hypertrophy but can sensitise cardiomyocytes to growth effects of serum. ( Bell, D; McDermott, BJ, 2000) |
| "Chronic administration of troglitazone might predispose to cardiac hypertrophy." | 3.70 | Troglitazone does not initiate hypertrophy but can sensitise cardiomyocytes to growth effects of serum. ( Bell, D; McDermott, BJ, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boitier, E | 1 |
| Amberg, A | 1 |
| Barbié, V | 1 |
| Blichenberg, A | 1 |
| Brandenburg, A | 1 |
| Gmuender, H | 1 |
| Gruhler, A | 1 |
| McCarthy, D | 1 |
| Meyer, K | 1 |
| Riefke, B | 1 |
| Raschke, M | 1 |
| Schoonen, W | 1 |
| Sieber, M | 1 |
| Suter, L | 1 |
| Thomas, CE | 1 |
| Sajot, N | 1 |
| Bell, D | 1 |
| McDermott, BJ | 1 |
2 other studies available for troglitazone and Hypertrophy
| Article | Year |
|---|---|
A comparative integrated transcript analysis and functional characterization of differential mechanisms for induction of liver hypertrophy in the rat.
Topics: Animals; Chemical and Drug Induced Liver Injury; Chromans; Gene Expression Profiling; Gene Regulator | 2011 |
Troglitazone does not initiate hypertrophy but can sensitise cardiomyocytes to growth effects of serum.
Topics: Animals; Cattle; Cell Differentiation; Cell Survival; Chromans; Culture Media; Dose-Response Relatio | 2000 |