troglitazone has been researched along with Follicular Thyroid Carcinoma in 2 studies
Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Troglitazone is a potent agonist for the peroxisome proliferator-activated receptor-gamma (PPARgamma) that is a ligand-activated transcription factor regulating cell differentiation and growth." | 1.33 | Troglitazone, the peroxisome proliferator-activated receptor-gamma agonist, induces antiproliferation and redifferentiation in human thyroid cancer cell lines. ( Clark, OH; Cotter, P; Duh, QY; Ginzinger, DG; Hyun, WC; Kanauchi, H; Lobo, M; Park, JW; Wong, MG; Zarnegar, R, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Park, JW | 1 |
| Zarnegar, R | 1 |
| Kanauchi, H | 1 |
| Wong, MG | 1 |
| Hyun, WC | 1 |
| Ginzinger, DG | 1 |
| Lobo, M | 1 |
| Cotter, P | 1 |
| Duh, QY | 1 |
| Clark, OH | 1 |
| Fröhlich, E | 1 |
| Machicao, F | 1 |
| Wahl, R | 1 |
2 other studies available for troglitazone and Follicular Thyroid Carcinoma
| Article | Year |
|---|---|
Troglitazone, the peroxisome proliferator-activated receptor-gamma agonist, induces antiproliferation and redifferentiation in human thyroid cancer cell lines.
Topics: Adenocarcinoma, Follicular; Cell Cycle; Cell Differentiation; Cell Division; Cell Line, Tumor; Chrom | 2005 |
Action of thiazolidinediones on differentiation, proliferation and apoptosis of normal and transformed thyrocytes in culture.
Topics: Adenocarcinoma, Follicular; Animals; Annexin A5; Apoptosis; Cell Differentiation; Cell Line, Transfo | 2005 |