troglitazone has been researched along with Fatigue in 2 studies
Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.
Fatigue: The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The management of Type 2 diabetes mellitus with currently available oral agents may be complicated in the elderly by an increased frequency of side-effects." | 6.69 | Troglitazone, an insulin action enhancer, improves glycaemic control and insulin sensitivity in elderly type 2 diabetic patients. ( Barnett, AH; Kumar, S; Lettis, S; Prange, A; Schulze, J, 1998) |
| "The management of Type 2 diabetes mellitus with currently available oral agents may be complicated in the elderly by an increased frequency of side-effects." | 2.69 | Troglitazone, an insulin action enhancer, improves glycaemic control and insulin sensitivity in elderly type 2 diabetic patients. ( Barnett, AH; Kumar, S; Lettis, S; Prange, A; Schulze, J, 1998) |
| "Troglitazone was effective in 394 (75%) of the 529 patients for whom an opinion was given." | 1.31 | Troglitazone and liver function abnormalities: lessons from a prescription event monitoring study and spontaneous reporting. ( Biswas, P; Shakir, SA; Wilton, LV, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kumar, S | 1 |
| Prange, A | 1 |
| Schulze, J | 1 |
| Lettis, S | 1 |
| Barnett, AH | 1 |
| Biswas, P | 1 |
| Wilton, LV | 1 |
| Shakir, SA | 1 |
1 trial available for troglitazone and Fatigue
| Article | Year |
|---|---|
Troglitazone, an insulin action enhancer, improves glycaemic control and insulin sensitivity in elderly type 2 diabetic patients.
Topics: Aged; Aged, 80 and over; Alanine Transaminase; Aspartate Aminotransferases; Blood Glucose; Chromans; | 1998 |
1 other study available for troglitazone and Fatigue
| Article | Year |
|---|---|
Troglitazone and liver function abnormalities: lessons from a prescription event monitoring study and spontaneous reporting.
Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Chromans; England; Fatigue; Female; Humans; Hyp | 2001 |