troglitazone has been researched along with Elevated Cholesterol in 3 studies
Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 68-year-old woman, with type 2 diabetes mellitus, hypercholesterolemia, and prior long-term simvastatin therapy, self-resumed troglitazone after running out of metformin." | 7.71 | Myositis, microvesicular hepatitis, and progression to cirrhosis from troglitazone added to simvastatin. ( Caldwell, SH; Hespenheide, EE; von Borstel, RW, 2001) |
| "Troglitazone is a newly developed antidiabetic drug that has been shown to improve insulin resistance and hyperinsulinemia both in diabetic animal models and in patients with non-insulin-dependent diabetes mellitus." | 7.69 | Quantification of the effects of troglitazone on insulin sensitivity and beta-cell function in Watanabe heritable hyperlipidemic rabbits: a minimal model analysis. ( Arakawa, K; Saku, K; Zhang, B, 1997) |
| "A 68-year-old woman, with type 2 diabetes mellitus, hypercholesterolemia, and prior long-term simvastatin therapy, self-resumed troglitazone after running out of metformin." | 3.71 | Myositis, microvesicular hepatitis, and progression to cirrhosis from troglitazone added to simvastatin. ( Caldwell, SH; Hespenheide, EE; von Borstel, RW, 2001) |
| "Troglitazone is a newly developed antidiabetic drug that has been shown to improve insulin resistance and hyperinsulinemia both in diabetic animal models and in patients with non-insulin-dependent diabetes mellitus." | 3.69 | Quantification of the effects of troglitazone on insulin sensitivity and beta-cell function in Watanabe heritable hyperlipidemic rabbits: a minimal model analysis. ( Arakawa, K; Saku, K; Zhang, B, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, B | 1 |
| Saku, K | 1 |
| Arakawa, K | 1 |
| Caldwell, SH | 1 |
| Hespenheide, EE | 1 |
| von Borstel, RW | 1 |
3 other studies available for troglitazone and Elevated Cholesterol
| Article | Year |
|---|---|
Quantification of the effects of troglitazone on insulin sensitivity and beta-cell function in Watanabe heritable hyperlipidemic rabbits: a minimal model analysis.
Topics: Animals; Blood Glucose; Chromans; Disease Models, Animal; Fasting; Female; Glucose Tolerance Test; H | 1997 |
Troglitazone for non-insulin-dependent diabetes mellitus.
Topics: Administration, Oral; Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 2; Dose-Response Relation | 1997 |
Myositis, microvesicular hepatitis, and progression to cirrhosis from troglitazone added to simvastatin.
Topics: Aged; Anticholesteremic Agents; Antioxidants; Chemical and Drug Induced Liver Injury; Chromans; Diab | 2001 |