troglitazone has been researched along with Chronic Kidney Failure in 4 studies
Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, there was a significant reduction in insulin dosage with troglitazone treatment (22." | 2.71 | The metabolic effects of troglitazone in patients with diabetes and end-stage renal disease. ( Arakaki, R; Bornemann, M; Genadio, V; Mohideen, P; Sugihara, J; Sugihara, V, 2005) |
| "Thus, diabetic nephropathy is currently the number one cause of end-stage renal disease in the Western world." | 2.43 | Protection of the kidney by thiazolidinediones: an assessment from bench to bedside. ( Bakris, GL; Sarafidis, PA, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Peng, Y | 1 |
| Liu, H | 1 |
| Liu, F | 1 |
| Wang, H | 1 |
| Liu, Y | 1 |
| Duan, S | 1 |
| Mohideen, P | 1 |
| Bornemann, M | 1 |
| Sugihara, J | 1 |
| Genadio, V | 1 |
| Sugihara, V | 1 |
| Arakaki, R | 1 |
| Sarafidis, PA | 1 |
| Bakris, GL | 1 |
| Yoshida, K | 1 |
| Kohzuki, M | 1 |
| Xu, HL | 1 |
| Wu, XM | 1 |
| Kamimoto, M | 1 |
| Sato, T | 1 |
1 review available for troglitazone and Chronic Kidney Failure
| Article | Year |
|---|---|
Protection of the kidney by thiazolidinediones: an assessment from bench to bedside.
Topics: Albuminuria; Animals; Blood Pressure; Chromans; Diabetes Mellitus, Type 2; Diabetic Nephropathies; E | 2006 |
1 trial available for troglitazone and Chronic Kidney Failure
| Article | Year |
|---|---|
The metabolic effects of troglitazone in patients with diabetes and end-stage renal disease.
Topics: Blood Glucose; Chromans; Diabetes Mellitus, Type 2; Female; Hemoglobin A; Humans; Hypoglycemic Agent | 2005 |
2 other studies available for troglitazone and Chronic Kidney Failure
| Article | Year |
|---|---|
Inhibitory effect of PPAR-gamma activator on IL-6 and mPGES protein expression in PBMC induced by homocysteine.
Topics: Cells, Cultured; Chromans; Dose-Response Relationship, Drug; Homocysteine; Humans; Interleukin-6; In | 2005 |
Effects of troglitazone and temocapril in spontaneously hypertensive rats with chronic renal failure.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Chromans; Humans; Hypertension; H | 2001 |