troglitazone has been researched along with Cell Transformation, Neoplastic in 3 studies
Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, K | 1 |
| Fan, KH | 1 |
| Lamprecht, SA | 1 |
| Edelmann, W | 1 |
| Kopelovich, L | 1 |
| Kucherlapati, R | 1 |
| Lipkin, M | 1 |
| He, G | 1 |
| Muga, S | 1 |
| Thuillier, P | 1 |
| Lubet, RA | 1 |
| Fischer, SM | 1 |
| Turturro, F | 1 |
| Driscoll, M | 1 |
| Friday, E | 1 |
| Welbourne, T | 1 |
3 other studies available for troglitazone and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Peroxisome proliferator-activated receptor gamma agonist troglitazone induces colon tumors in normal C57BL/6J mice and enhances colonic carcinogenesis in Apc1638 N/+ Mlh1+/- double mutant mice.
Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents; Carcinogens; Carrier Proteins; | 2005 |
The effect of PPARgamma ligands on UV- or chemically-induced carcinogenesis in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Proliferation; Cell Transformation, Neo | 2005 |
ALK-mediated Na+/H+ exchanger-dependent intracellular alkalinization: does it matter for oncogenesis?
Topics: Alanine; Ammonia; Animals; Cell Division; Cell Line, Tumor; Cell Transformation, Neoplastic; Chroman | 2007 |