troglitazone has been researched along with Carcinoma in 3 studies
Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.
Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We previously reported that the PPARgamma agonist troglitazone (TRO) inhibits proliferation and induces apoptosis in human MCF-7 breast carcinoma cells." | 7.72 | Signaling pathways involved in induction of GADD45 gene expression and apoptosis by troglitazone in human MCF-7 breast carcinoma cells. ( Blaschke, F; Bruemmer, D; Herle, AJ; Hsueh, WA; Law, RE; Yin, F, 2004) |
| "Troglitazone and 15dPGJ2 inhibit growth of prostate and bladder carcinoma cell lines through different mechanisms and the effects of both agents are PPARgamma-independent." | 3.73 | PPARgamma-independent induction of growth arrest and apoptosis in prostate and bladder carcinoma. ( Chaffer, CL; Thomas, DM; Thompson, EW; Williams, ED, 2006) |
| "We previously reported that the PPARgamma agonist troglitazone (TRO) inhibits proliferation and induces apoptosis in human MCF-7 breast carcinoma cells." | 3.72 | Signaling pathways involved in induction of GADD45 gene expression and apoptosis by troglitazone in human MCF-7 breast carcinoma cells. ( Blaschke, F; Bruemmer, D; Herle, AJ; Hsueh, WA; Law, RE; Yin, F, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yin, F | 1 |
| Bruemmer, D | 1 |
| Blaschke, F | 1 |
| Hsueh, WA | 1 |
| Law, RE | 1 |
| Herle, AJ | 1 |
| Chaffer, CL | 1 |
| Thomas, DM | 1 |
| Thompson, EW | 1 |
| Williams, ED | 1 |
| Toyota, M | 1 |
| Miyazaki, Y | 1 |
| Kitamura, S | 1 |
| Nagasawa, Y | 1 |
| Kiyohara, T | 1 |
| Shinomura, Y | 1 |
| Matsuzawa, Y | 1 |
3 other studies available for troglitazone and Carcinoma
| Article | Year |
|---|---|
Signaling pathways involved in induction of GADD45 gene expression and apoptosis by troglitazone in human MCF-7 breast carcinoma cells.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Carcinoma; Cell Cycle; Chromans; Enzyme Inhibito | 2004 |
PPARgamma-independent induction of growth arrest and apoptosis in prostate and bladder carcinoma.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma; Carcinoma, Transitional Cell; Caspase 3; Caspase 7; Cas | 2006 |
Peroxisome proliferator-activated receptor gamma reduces the growth rate of pancreatic cancer cells through the reduction of cyclin D1.
Topics: Alitretinoin; Animals; Antineoplastic Agents; Blotting, Northern; Blotting, Western; Carcinoma; Cell | 2002 |