troglitazone has been researched along with Cancer of Stomach in 9 studies
Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Among three gastric cancer cell lines, MKN28, MKN45, and MKN74, only the most poorly differentiated MKN45 cells survived >36 h." | 1.31 | Remarkable tolerance of tumor cells to nutrient deprivation: possible new biochemical target for cancer therapy. ( Esumi, H; Izuishi, K; Kato, K; Kinoshita, T; Ogura, T, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 6 (66.67) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, Y | 1 |
| Zhu, ZA | 1 |
| Zhang, SN | 1 |
| Mou, J | 1 |
| Liu, L | 1 |
| Cui, T | 1 |
| Pei, DS | 1 |
| Cheon, CW | 1 |
| Kim, DH | 2 |
| Cho, YH | 1 |
| Kim, JH | 1 |
| Chen, Q | 1 |
| Zhou, J | 1 |
| Jiang, C | 1 |
| Chen, J | 1 |
| Takeuchi, S | 1 |
| Okumura, T | 2 |
| Motomura, W | 2 |
| Nagamine, M | 2 |
| Takahashi, N | 2 |
| Kohgo, Y | 2 |
| Tanno, S | 1 |
| Sawamukai, M | 1 |
| Lu, J | 1 |
| Imamura, K | 1 |
| Nomura, S | 1 |
| Mafune, K | 1 |
| Nakajima, A | 1 |
| Kadowaki, T | 1 |
| Kubota, N | 1 |
| Terauchi, Y | 1 |
| Ishii, G | 1 |
| Ochiai, A | 1 |
| Esumi, H | 2 |
| Kaminishi, M | 1 |
| Kitamura, S | 1 |
| Miyazaki, Y | 1 |
| Hiraoka, S | 1 |
| Toyota, M | 1 |
| Nagasawa, Y | 1 |
| Kondo, S | 1 |
| Kiyohara, T | 1 |
| Shinomura, Y | 1 |
| Matsuzawa, Y | 1 |
| Izuishi, K | 1 |
| Kato, K | 1 |
| Ogura, T | 1 |
| Kinoshita, T | 1 |
| Morita, D | 1 |
| Ichikura, T | 1 |
| Mochizuki, H | 1 |
1 review available for troglitazone and Cancer of Stomach
| Article | Year |
|---|---|
[The expression of PPAR gamma in gastric cancer].
Topics: Animals; Antineoplastic Agents; Cell Division; Chromans; Humans; Ligands; Receptors, Cytoplasmic and | 2001 |
8 other studies available for troglitazone and Cancer of Stomach
| Article | Year |
|---|---|
Combinational effect of PPARĪ³ agonist and RXR agonist on the growth of SGC7901 gastric carcinoma cells in vitro.
Topics: Alitretinoin; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Cell Line, Tumor; Cell P | 2013 |
Effects of ciglitazone and troglitazone on the proliferation of human stomach cancer cells.
Topics: Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Shape; Chromans; Cyclin-Dependent Kinase Inhi | 2009 |
Reversal of P-glycoprotein-mediated multidrug resistance in SGC7901/VCR cells by PPARgamma activation by troglitazone.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transport | 2010 |
Troglitazone induces G1 arrest by p27(Kip1) induction that is mediated by inhibition of proteasome in human gastric cancer cells.
Topics: Antineoplastic Agents; Blotting, Northern; Blotting, Western; Cell Cycle; Cell Cycle Proteins; Cell | 2002 |
PPAR gamma ligand-induced apoptosis through a p53-dependent mechanism in human gastric cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle Proteins; Cell Division; Chromans; Cyclin-Dependent Kin | 2003 |
Chemopreventive effect of peroxisome proliferator-activated receptor gamma on gastric carcinogenesis in mice.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Chromans; Female; Gastric Mucosa; Ligands; Male; Meth | 2005 |
PPARgamma inhibits the expression of c-MET in human gastric cancer cells through the suppression of Ets.
Topics: Cell Division; Chromans; Gene Expression; Humans; Promoter Regions, Genetic; Proto-Oncogene Protein | 1999 |
Remarkable tolerance of tumor cells to nutrient deprivation: possible new biochemical target for cancer therapy.
Topics: Antineoplastic Agents; Cell Survival; Chromans; Chromones; Culture Media, Serum-Free; Enzyme Activat | 2000 |