troglitazone has been researched along with Cancer of Ovary in 3 studies
Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.
Excerpt | Relevance | Reference |
---|---|---|
"CGZ and TGZ cause a decrease in ovarian cancer cell proliferation that is PPARγ independent." | 1.37 | Specific thiazolidinediones inhibit ovarian cancer cell line proliferation and cause cell cycle arrest in a PPARγ independent manner. ( Al-Alem, L; Curry, TE; Kilgore, MW; Southard, RC, 2011) |
"Troglitazone (TGZ) is a potential anticancer agent." | 1.34 | Inhibition of cell motility by troglitazone in human ovarian carcinoma cell line. ( Chen, SL; Ho, TC; Lai, HY; Tsao, YP; Wu, JY; Yang, YC, 2007) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (33.33) | 29.6817 |
2010's | 2 (66.67) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Bräutigam, K | 1 |
Biernath-Wüpping, J | 1 |
Bauerschlag, DO | 1 |
von Kaisenberg, CS | 1 |
Jonat, W | 1 |
Maass, N | 1 |
Arnold, N | 1 |
Meinhold-Heerlein, I | 1 |
Al-Alem, L | 1 |
Southard, RC | 1 |
Kilgore, MW | 1 |
Curry, TE | 1 |
Yang, YC | 1 |
Ho, TC | 1 |
Chen, SL | 1 |
Lai, HY | 1 |
Wu, JY | 1 |
Tsao, YP | 1 |
3 other studies available for troglitazone and Cancer of Ovary
Article | Year |
---|---|
Combined treatment with TRAIL and PPARγ ligands overcomes chemoresistance of ovarian cancer cell lines.
Topics: Apoptosis; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspase 8; Cell Line, Tumor; Chromans; | 2011 |
Specific thiazolidinediones inhibit ovarian cancer cell line proliferation and cause cell cycle arrest in a PPARγ independent manner.
Topics: Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chromans; Female; Gene Expression; Humans; Ovarian | 2011 |
Inhibition of cell motility by troglitazone in human ovarian carcinoma cell line.
Topics: Cell Line, Tumor; Cell Movement; Chromans; Dose-Response Relationship, Drug; Female; Humans; Ovarian | 2007 |