Page last updated: 2024-11-05

troglitazone and Cancer of Ovary

troglitazone has been researched along with Cancer of Ovary in 3 studies

Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.

Research Excerpts

ExcerptRelevanceReference
"CGZ and TGZ cause a decrease in ovarian cancer cell proliferation that is PPARγ independent."1.37Specific thiazolidinediones inhibit ovarian cancer cell line proliferation and cause cell cycle arrest in a PPARγ independent manner. ( Al-Alem, L; Curry, TE; Kilgore, MW; Southard, RC, 2011)
"Troglitazone (TGZ) is a potential anticancer agent."1.34Inhibition of cell motility by troglitazone in human ovarian carcinoma cell line. ( Chen, SL; Ho, TC; Lai, HY; Tsao, YP; Wu, JY; Yang, YC, 2007)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bräutigam, K1
Biernath-Wüpping, J1
Bauerschlag, DO1
von Kaisenberg, CS1
Jonat, W1
Maass, N1
Arnold, N1
Meinhold-Heerlein, I1
Al-Alem, L1
Southard, RC1
Kilgore, MW1
Curry, TE1
Yang, YC1
Ho, TC1
Chen, SL1
Lai, HY1
Wu, JY1
Tsao, YP1

Other Studies

3 other studies available for troglitazone and Cancer of Ovary

ArticleYear
Combined treatment with TRAIL and PPARγ ligands overcomes chemoresistance of ovarian cancer cell lines.
    Journal of cancer research and clinical oncology, 2011, Volume: 137, Issue:5

    Topics: Apoptosis; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspase 8; Cell Line, Tumor; Chromans;

2011
Specific thiazolidinediones inhibit ovarian cancer cell line proliferation and cause cell cycle arrest in a PPARγ independent manner.
    PloS one, 2011, Jan-21, Volume: 6, Issue:1

    Topics: Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chromans; Female; Gene Expression; Humans; Ovarian

2011
Inhibition of cell motility by troglitazone in human ovarian carcinoma cell line.
    BMC cancer, 2007, Nov-20, Volume: 7

    Topics: Cell Line, Tumor; Cell Movement; Chromans; Dose-Response Relationship, Drug; Female; Humans; Ovarian

2007