troglitazone has been researched along with Atherosclerosis in 3 studies
Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.
Atherosclerosis: A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Insulin sensitization and reduction in blood pressure may be contributory mechanisms by which troglitazone reduced subclinical atherosclerosis progression in this cohort of well-controlled insulin-dependent patients with clinical characteristics suggesting type 2 diabetes." | 5.12 | Effect of peroxisome proliferator-activated receptor gamma agonist treatment on subclinical atherosclerosis in patients with insulin-requiring type 2 diabetes. ( Alaupovic, P; Buchanan, TA; Garcia, K; Hodis, HN; Hollen, B; Li, Y; Mack, WJ; Sevilla, D; Stewart, Y; Torres, M; Zheng, L, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tsai, JS | 1 |
| Chuang, LM | 1 |
| Chen, CS | 1 |
| Liang, CJ | 1 |
| Chen, YL | 1 |
| Chen, CY | 1 |
| McCarthy, C | 1 |
| O'Gaora, P | 1 |
| James, WG | 1 |
| de Gaetano, M | 1 |
| McClelland, S | 1 |
| Fitzgerald, DJ | 1 |
| Belton, O | 1 |
| Hodis, HN | 1 |
| Mack, WJ | 1 |
| Zheng, L | 1 |
| Li, Y | 1 |
| Torres, M | 1 |
| Sevilla, D | 1 |
| Stewart, Y | 1 |
| Hollen, B | 1 |
| Garcia, K | 1 |
| Alaupovic, P | 1 |
| Buchanan, TA | 1 |
1 trial available for troglitazone and Atherosclerosis
| Article | Year |
|---|---|
Effect of peroxisome proliferator-activated receptor gamma agonist treatment on subclinical atherosclerosis in patients with insulin-requiring type 2 diabetes.
Topics: Adult; Aged; Atherosclerosis; Carotid Artery, Common; Chromans; Diabetes Mellitus, Type 2; Double-Bl | 2006 |
2 other studies available for troglitazone and Atherosclerosis
| Article | Year |
|---|---|
Troglitazone and Δ2Troglitazone enhance adiponectin expression in monocytes/macrophages through the AMP-activated protein kinase pathway.
Topics: Adiponectin; AMP-Activated Protein Kinases; Animals; Atherosclerosis; Cell Adhesion; Cell Line; Chro | 2014 |
SorLA modulates atheroprotective properties of CLA by regulating monocyte migration.
Topics: Animals; Atherosclerosis; Cell Movement; Chemokine CCL2; Chromans; Humans; Linoleic Acids, Conjugate | 2010 |